Effect of Moringa oleifera soup on primary dysmenorrhea in adolescent girls

Background: Dysmenorrhea causes a substantial burden on the quality of life of female adolescents. The prevalence estimates range from 25 to 90%. Hence this study aimed to evaluate the effect of Moringa oleifera (MO) soup on primary dysmenorrhea in adolescent girls.Methods: This interventional clinical study was conducted on 111 adolescent college-going girls. Age, anthropometric data (height, weight), age of menarche, presence and absence of primary dysmenorrhea (PD), menses irregularities and other associated symptoms were collected primarily through the prepared standard questioners. Based on the collected data, 40 primary dysmenorrheal participants were selected and further, the information was collected regarding primary dysmenorrhea associated symptoms like back pain, abdominal pain, headaches, leg cramps, painful/tender breasts, acne, tiredness, anger, mood swing, insomnia, altered appetite, nausea/vomiting or diarrhea. The hemoglobin and red blood count were evaluated in the PD participants. Both the hematological and dysmenorrhea-associated parameters were assessed before and after treatment of MO leaf soup.Results: Our study results showed that the prevalence of dysmenorrhea is 36%. Dysmenorrhea participants had the most frequent (every month), painful, irregular and longer length of the menstrual cycle. The dysmenorrheal pain was most frequent, shorten, moderately intense and the higher percentage in the lower abdomen, lower side and pain at a different locations. Dysmenorrhea-associated illnesses like tiredness, abdominal pain, back pain, anger and irritability, leg cramps, and mood swings were higher in participants with dysmenorrhea. After administration of MO leaf soup significantly improves the hemoglobin and RBC levels in PD participants. Also, improve the menstrual as well as pain-associated symptoms of PD.Conclusions: In conclusion intake of MO soup effectively improves the primary dysmenorrhea associated menstrual as well pain as symptoms and corrects the anemia condition by increasing the hemoglobin and RBC levels in adolescent girls with dysmenorrhea.

Harbingers of Hope: Scientists and the Pursuit of World Peace

The ongoing wars in many regions-such as the conflict between Israel and Hamas-as well as the effects of war on communities, social services, and mental health are covered in this special editorial. This article emphasizes the need for international efforts to promote peace, offer humanitarian aid, and address the mental health challenges faced by individuals and communities affected by war and violence

Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs

: AIMS/HYPOTHESIS: Evaluation of the association of 31 common single nucleotide polymorphisms (SNPs) with fasting glucose, fasting insulin, HOMA-beta cell function (HOMA-?), HOMA-insulin resistance (HOMA-IR) and type 2 diabetes in the Indian population. METHODS: We genotyped 3,089 sib pairs recruited in the Indian Migration Study from four cities in India (Lucknow, Nagpur, Hyderabad and Bangalore) for 31 SNPs in 24 genes previously associated with type 2 diabetes in European populations. We conducted within-sib-pair analysis for type 2 diabetes and its related quantitative traits. RESULTS: The risk-allele frequencies of all the SNPs were comparable with those reported in western populations. We demonstrated significant associations of CXCR4 (rs932206), CDKAL1 (rs7756992) and TCF7L2 (rs7903146, rs12255372) with fasting glucose, with ? values of 0.007 (p?=?0.05), 0.01 (p?=?0.01), 0.007 (p?=?0.05), 0.01 (p?=?0.003) and 0.08 (p?=?0.01), respectively. Variants in NOTCH2 (rs10923931), TCF-2 (also known as HNF1B) (rs757210), ADAM30 (rs2641348) and CDKN2A/B (rs10811661) significantly predicted fasting insulin, with ? values of -0.06 (p?=?0.04), 0.05 (p?=?0.05), -0.08 (p?=?0.01) and -0.08 (p?=?0.02), respectively. For HOMA-IR, we detected associations with TCF-2, ADAM30 and CDKN2A/B, with ? values of 0.05 (p?=?0.04), -0.07 (p?=?0.03) and -0.08 (p?=?0.02), respectively. We also found significant associations of ADAM30 (??=?-0.05; p?=?0.01) and CDKN2A/B (??=?-0.05; p?=?0.03) with HOMA-?. THADA variant (rs7578597) was associated with type 2 diabetes (OR 1.5; 95% CI 1.04, 2.22; p?=?0.03). CONCLUSIONS/INTERPRETATION: We validated the association of seven established loci with intermediate traits related to type 2 diabetes in an Indian population using a design resistant to population stratification

Performance characteristics of SLI batteries assembled according to process

A process know - how for commercial production of lead - acid batteries of SLI type has been developed in this Institute. The batteries ranging in capacity from 60Ah to 135Ah were tested according to 1337372 - 1974 and found to pass all the tests successfully. In this paper the performance characteristics are reported and discusse

An attempt to understand the behavior of dissolved organic carbon in coastal aquifers of Pondicherry region, South India

Groundwaters of the coastal region are significant and serve as a fragile ecosystem in the sedimentary terrain. The Pondicherry region is characterized by different geological formations of distinct geological epochs Cretaceous, Tertiary and Quaternary. Ninety-three samples were collected from specific aquifers with respect to spatial distribution [Alluvium (31), Upper Cuddalore (13), Lower Cuddalore (13), Other Tertiary (7), Cretaceous (24) and Mixed—multiple completion aquifer (5)]. The collected samples were analyzed for major ions Ca2+, Mg2+, Na+, K+, HCO3−, Cl−, PO42−, SO42−, F and DOC. Stables isotopes of δ18O, δD and δ 13C were also analyzed along with heavy metals like Al, Ba, Fe, Sr, Cd and Zn. The δ18O ranges between −6.85 and −2.15 ‰, and δD ranges between −43.94 and −19.41 ‰. The distribution of these environmental isotopes in groundwater of this layered aquifer sequence was also attempted. A comparison of the isotopic data with the rainfall, Local Meteoric Water Line with a equation of δD = 7.398 * δ18O + 5.067, Indian Meteoric Water Line and Global Meteoric Water Line was performed. The δ13C values for groundwater ranges from −5.3 to −18.1 ‰. The result indicates that the groundwater in the study area is mainly meteoric in origin, and few samples show evidence of evaporation. The dissolved organic carbon (DOC) is a very important component in biogeochemical cycling of elements characterized by high susceptibility to leaching. The range of the DOC in the study area is 0–16 mg/L. Factor analysis was applied to classify the groundwater samples and to identify geochemical processes controlling groundwater geochemistry. The Alluvium aquifers show a complex hydrogeochemistry than the older aquifers. The major factor influencing the hydrogeochemistry of the region is rock–water interaction and anthropogenic processes. Hence, metal mobility of the groundwater shows the correlation of metal bonding and DOC. The relation between the DOC and heavy metal concentration in the aquifers was also identified

Dissolved Organic Carbon in Multilayered Aquifers of Pondicherry Region (India): Spatial and Temporal Variability and Relationships to Major Ion Chemistry

Carbon, which is an essential element found in rocks and minerals, is used by biologically diverse life forms as a source of energy. Natural organic carbon is mainly derived from decomposing vegetation and other organic matter in the soil zone. Dissolved organic carbon (DOC) is an important component in biogeochemical cycling of elements characterized by high susceptibility to leaching. The significance of DOC was studied in layered coastal aquifers of the Pondicherry region during four different seasons. Pondicherry region has varied geological setup ranging from Cretaceous to Recent formations. A total of 324 groundwater samples were collected from various aquifers, namely Alluvium, Tertiary, Cretaceous, and Mixed formations, during different seasons of pre-monsoon, southwest monsoon, northeast monsoon, and post-monsoon. The samples were analyzed for major ions and DOC. The range of DOC in the study area is 0–10 mg/l. Very high DOC concentrations were measured in most of the samples from Alluvium and Upper Cuddalore Formation and in few samples from the Lower Cuddalore Formation. The relationships of DOC with other ions in this study indicate that the hydrochemistry of groundwater was controlled by both aerobic and anaerobic environments in the different formations of the study area