Bronchogenic cyst and pharyngeal fistula in an 81 year old female: a case report

A CAJM article on Bronchogenic cyst and pharyngeal fistular in an 81 year old female.Bronchogenic cyst is a rare clinical; entity that occurs due to an anomalous development of the ventral foregut; they are usually single but may be multiple and can be filled with fluid or mucus. They have been found all along the transoesophageal course, in perihilar or intraparenchymal sites, with predilection for the area around the carina. The location of the cyst depends on the embryonic stage of development at which the anomaly occurs. When the abnormal budding occurs during the early development, the cyst tends to be located along the tracheobronchial tree. The cysts that develop later during the late development are more peripheral and may be located within the lung parenchyma. Bronchogenic cysts have also been described in more remote locations, including neck, interatrial septum, abdomen, and retroperitoneal space. Past reports emphasised that a bronchogenic cyst is usually asymptomatic and presents as an incidental finding, but more recent reports suggest that the majority of adults with bronchogenic cysts ultimately become symptomatic. The actual natural history and percentage of asymptomatic bronchogenic cyst in adults are not known because of the absence of long term follow up of a large group of patients with asymptomatic cyst. Symptomatic patients usually present with symptomatic related to cyst infection or compression of adjacent structures. Presentation in the elderly population is quite rare. It has been reported that approximately 0,6% of such cyst are noted in patients above the age of 60 years. Total documented cases of patients presenting after the age of 70 years have been noted to be only 8 in 2002

Numerical studies of nanofluid boundary layer flows using spectral methods.

Doctoral Degree. University of KwaZulu-Natal, PietermaritzburgThis thesis is focused on numerical studies of heat and mass transport processes that occur in nanofluid boundary layer flows. We investigate heat and mass transfer mechanisms in the flow of a micropolar nanofluid above a stretching sheet, the squeezed nanofluid flow between two parallel plates and the impact of activation energy and binary chemical reaction on nanofluid flow past a rotating disk. We present an analysis of entropy generation in nanofluid flow past a rotating disk and nanofluid flow past a stretching surface under the influence of an inclined magnetic field. This study aims to numerically determine to a high degree of accuracy, how nanoparticles can be utilized to alter heat and transport properties of base fluids in order to enhance or achieve desirable properties for thermal systems. The heat and mass transfer processes that feature in nanofluid boundary layer flow are described by complex nonlinear transport equations which are difficult to solve. Because of the complex nature of the constitutive equations describing the flow of nanofluids, finding analytic solutions has often proved intractable. In this study, the model equations are solved using the spectral quasilinearization method. This method is relatively recent and has not been adequately utilized by researchers in solving related problems. The accuracy and reliability of the method are tested through convergence error and residual error analyses. The accuracy is further tested through a comparison of results for limiting cases with those in the literature. The results confirm the spectral quasilinearization method as being accurate, efficient, rapidly convergent and suited for solving boundary value problems. In addition, among other findings, we show that nanofluid concentration enhances heat and mass transfer rates while the magnetic field reduces the velocity distribution. The fluid flows considered in this study have significant applications in science, engineering and technology. The findings will contribute to expanding the existing knowledge on nanofluid flow

Diversion Programmes and Empowerment: A Case Study of Young Offenders’ Experiences in the Buffalo City Metropolitan and Amathole District Municipalities in the Eastern Cape Province of South Africa

Crime amongst the young in South Africa has been high since the attainment of democracy in 1994. Diversion programmes were established through the National Framework Chid Justice Act of 2008, as part of a plethora of measures to curb the ever spiralling problem of crime amongst the youth. The purpose of this thesis was to investigate the experiences of young offenders regarding their empowerment vis-à-vis diversion programmes in the Buffalo City Metropolitan and Amathole District Municipalities in the Eastern Cape Province. Underpinned by the Empowerment and Social Control Theories, the study adopted a qualitative research paradigm and used focus group discussions and in-depth interviews amongst thirty-five young offenders and five social workers, who work as probation officers at NICRO, to collect data, which was analysed using thematic analysis. The major findings indicated that diversion programmes are effective in reducing the number of children who commit crimes in these two municipalities and in influencing their behavioural change, resulting in fewer chances of re-offending. The Life Skills Programme was identified as the most effective programme, in comparison to the other programmes, such as the Community pre-trial Service Programme, in changing the behaviour of the young offenders, as it helps them to discover themselves; learn respect for the self and others in the community; help with family and community reintegration; and helps them focus on who they want to be in the future. In spite of such positive attributes for the diversion programmes, the study observed that there are challenges being faced by the implementing organisation, NICRO. These include high caseloads; lack of support from the probation officers who refer young offenders; limited support from parents; paucity of financial resources; lack of transport; poor v coordination from the courts; and delays in the implementation of some accredited but not credited programmes. Overall, the study concluded that diversion programmes in the Buffalo city Metropolitan and Amathole district municipalities in the Eastern Cape suffer due to weak partnerships between different organisations and stakeholders that are supposed to complement the efforts of the judiciary. From the research findings above, it is recommended that the Child Justice System should promote a multi-sectored approach in order to restore and reunify all the stakeholders, working with children in conflict with the law. This adds more roles and responsibilities for the various stakeholders, such as the Department of Justice and Department of Social development. Furthermore, there is a need to increase the monitoring and evaluation of diversion programmes to advance accountability and improve effectiveness; and there is a need to enhance the efficiency of accrediting authorities to timeously accredit other diversion programmes that, so far, have not yet been accredited, but may be useful in empowering young offenders. Therefore, the study proposes an extension of the framework with additions of strategies to support diversion programmes at NICRO, through a stakeholder extension to the model allocating more roles and responsibilities for stakeholders in the Child Justice system, in order for diversion programmes to effectively achieve desired goals

A critical investigation of the relevance of theories of feminist jurisprudence to African women in South Africa

Feminist theories emerged out of the revolutionary enthusiasm that swept the Western world during the late eighteenth and nineteenth century Europe. Based on the assumption that all persons have "inalienable or natural" rights upon which governments may not intrude, feminists in Europe and America advocated that equal rights should be extended to women who up to this point were not considered legal beings separate and deserving of these rights. Most African writers and feminists have argued that since most of the theories of feminist jurisprudence have their roots in this Euro-centric context, they cannot be applicable to African women and should therefore be discarded. The thesis acknowledges that to a certain extent their assertions are true. For years feminist jurisprudence has been restricted to an academic engagement with the law failing to take into account the practices and customs of different communities. It has largely been the realm of the middle class bourgeois white female and therefore has been inaccessible to the African woman. The thesis aims, however, to prove that these theories of feminist jurisprudence although Euro-centric have a place in the understanding and advancement of African women's rights in South Africa. In Chapter One the writer traces the history of South African women's rights and the laws that affect African women. Chapter Two presents the emergence of feminist theories and categories of feminism. The writer then seeks to identify the misunderstandings and tensions that exist between the two. The narrow conception of Euro-centric feminism has been that its sole purpose has been the eradication of gender discrimination, however, for African women in South Africa they have had to deal with a multiplicity of oppressions that include but are not restricted to gender, race, economic and social disempowerment. This is dealt with in Chapter Three. It is the opinion of the writer that despite these differences feminism does play a critical role in the advancement of women's rights in South Africa. Taking the South African governments commitment to the advancement of universal rights, the writer is of the opinion that African women can look to the example set by Western feminists, and broaden these theories to suit and be adaptable to the South African context. The answer is not to totally discard feminist theories but to extract commonalities that exist between African and European women, by so doing acknowledging that women's oppression is a global phenomenon. This is the focus of Chapter Four. To avoid making this work a mere academic endeavour, the writer in Chapter Five also aims, through interviews, to include the voices of African women and to indicate areas that still need attention from both the lawmakers and women's rights movements (Feminists). Finally, the writer aims to present a way forward, one that is not merely formal but also substantively attainable

Diversion Programmes and Empowerment: A Case Study of Young Offenders’ Experiences in the Buffalo City Metropolitan and Amathole District Municipalities in the Eastern Cape Province of South Africa

Crime amongst the young in South Africa has been high since the attainment of democracy in 1994. Diversion programmes were established through the National Framework Chid Justice Act of 2008, as part of a plethora of measures to curb the ever spiralling problem of crime amongst the youth. The purpose of this thesis was to investigate the experiences of young offenders regarding their empowerment vis-à-vis diversion programmes in the Buffalo City Metropolitan and Amathole District Municipalities in the Eastern Cape Province. Underpinned by the Empowerment and Social Control Theories, the study adopted a qualitative research paradigm and used focus group discussions and in-depth interviews amongst thirty-five young offenders and five social workers, who work as probation officers at NICRO, to collect data, which was analysed using thematic analysis. The major findings indicated that diversion programmes are effective in reducing the number of children who commit crimes in these two municipalities and in influencing their behavioural change, resulting in fewer chances of re-offending. The Life Skills Programme was identified as the most effective programme, in comparison to the other programmes, such as the Community pre-trial Service Programme, in changing the behaviour of the young offenders, as it helps them to discover themselves; learn respect for the self and others in the community; help with family and community reintegration; and helps them focus on who they want to be in the future. In spite of such positive attributes for the diversion programmes, the study observed that there are challenges being faced by the implementing organisation, NICRO. These include high caseloads; lack of support from the probation officers who refer young offenders; limited support from parents; paucity of financial resources; lack of transport; poor v coordination from the courts; and delays in the implementation of some accredited but not credited programmes. Overall, the study concluded that diversion programmes in the Buffalo city Metropolitan and Amathole district municipalities in the Eastern Cape suffer due to weak partnerships between different organisations and stakeholders that are supposed to complement the efforts of the judiciary. From the research findings above, it is recommended that the Child Justice System should promote a multi-sectored approach in order to restore and reunify all the stakeholders, working with children in conflict with the law. This adds more roles and responsibilities for the various stakeholders, such as the Department of Justice and Department of Social development. Furthermore, there is a need to increase the monitoring and evaluation of diversion programmes to advance accountability and improve effectiveness; and there is a need to enhance the efficiency of accrediting authorities to timeously accredit other diversion programmes that, so far, have not yet been accredited, but may be useful in empowering young offenders. Therefore, the study proposes an extension of the framework with additions of strategies to support diversion programmes at NICRO, through a stakeholder extension to the model allocating more roles and responsibilities for stakeholders in the Child Justice system, in order for diversion programmes to effectively achieve desired goals

DESCRIPTION OF MENINGITIS EPIDEMIC IN HAIKOCH NA BUTAJIRA DISTRICT

ABSTRACT: A retrospective review of a recent meningitis epidemic in Haikoch na Butajira District for the months of February and March 1989 was conducted. The epidemic is described in terms of person, place and time. The relationship of the epidemic with weather changes (rainfall and temperature) is assessed. There were a total of 6968 reported cases of meningitis with 203 deaths. The case fatality rate was 2.9%. The male to female ratio was 1.05 to 1. The peak of the epidemic was found to be during the second half of the month of February. There were 864 cases from urban, 3321 from villagized and 2783 from non villagized areas giving period prevalence rates of 6%, 8% and 2%, respectively, during the two months. Based on this study, surveillance and control recommendations are made

Determining the adrenocortical activity as a measure of stress in domestic pigs (Sus scrofa domesticus) based on salivary and faecal analysis

Domestic pigs are subjected to farm management procedures, some of which might be perceived as causing stress and therefore may have welfare concerns. When confronted with a stressor, animals display a response that consists of a suite of physiological and behavioural alterations to restore homeostasis. Physiologically, the response is usually determined using glucocorticoid concentrations (GC) albeit invasively, with the disadvantage of a possible handling-induced stress response. To date, no non-invasive method exists for determining stress-related responses in pigs. This study aimed to examine the suitability of enzyme-immunoassays (EIAs) for determining GC concentrations in saliva and faeces of domestic pigs by performing an ACTH challenge. A total of 6 animals were studied with 4 receiving 10µg/kg of Synacthen® (Novartis, South Africa Pty Ltd) and the remaining 2 receiving 0.5 ml physiologic saline. Baseline salivary glucocorticoid (sGC) concentrations of 2.38±1.83ng/ml (mean±SEM) increased by six-fold (14.03±6.83 ng/ml) within 40-90 minutes after administration of ACTH (P < 0.0001) and the elevated salivary cortisol levels were maintained for up to nine hours. Administration of saline caused no significant differences in sGC concentrations (P = 0.82). Similarly, baseline faecal glucocorticoid metabolite (fGCM) level of 235±46μg/g rose significantly up to 393±164μg/g within 36 hours post ACTH administration (P < 0.0001). No significant difference was found between baseline and post saline administration (P = 0.57). Significantly higher sGC concentrations were found in samples collected in the morning compared to those collected in the afternoon, indicating a circadian rhythm. In terms of stability of fGCMs, post-defecation levels only changed by 4% over the course of 50h (P = 0.76). In conclusion, EIAs can be used to determine sGC and fGCM concentrations to assess adrenocortical function in pigs. FGCM levels are relatively stable for at least two days post-defecation, which facilitates field sample submissions.Poster presented at the University of Pretoria, Faculty of Veterinary Science Faculty Day, August 25, 2016, Pretoria, South Africa.ab201

Factors Affecting the Propensity of Tsetse Flies to Enter Houses and Attack Humans Inside: Increased Risk of Sleeping Sickness in Warmer Climates

Background Sleeping sickness, or human African trypanosomiasis, is caused by two species of Trypanosoma brucei that are transmitted to humans by tsetse flies (Glossina spp.) when these insects take a bloodmeal. It is commonly assumed that humans must enter the normal woodland habitat of the flies to become infected, but recent studies found that tsetse frequently attack humans inside buildings. Factors affecting human/tsetse contact in buildings need identification. Methodology/Principal Findings In Zimbabwe, tsetse were allowed access to a house via an open door. Those in the house at sunset, and those alighting on humans in the house during the day, were caught using hand-nets. Total catches were unaffected by: (i) the presence of humans in the house and at the door, (ii) wood smoke from a fire inside the house or just outside, (iii) open windows, and (iv) chemicals simulating the odor of cattle or of humans. Catches increased about 10-fold with rising ambient temperatures, and during the hottest months the proportion of the total catch that was taken from the humans increased from 5% to 13%. Of the tsetse caught from humans, 62% consisted of female G. morsitans morstans and both sexes of G. pallidipes, i.e., the group of tsetse that normally alight little on humans. Some of the tsetse caught were old enough to be effective vectors. Conclusion/Significance Present results confirm previous suggestions that buildings provide a distinctive and important venue for transmission of sleeping sickness, especially since the normal repellence of humans and smoke seems poorly effective in such places. The importance of the venue would be increased in warmer climates

Costs Of Using “Tiny Targets” to Control Glossina fuscipes fuscipes, a Vector of Gambiense Sleeping Sickness in Arua District of Uganda

Introduction To evaluate the relative effectiveness of tsetse control methods, their costs need to be analysed alongside their impact on tsetse populations. Very little has been published on the costs of methods specifically targeting human African trypanosomiasis. Methodology/Principal Findings In northern Uganda, a 250 km2 field trial was undertaken using small (0.5 X 0.25 m) insecticide-treated targets (“tiny targets”). Detailed cost recording accompanied every phase of the work. Costs were calculated for this operation as if managed by the Ugandan vector control services: removing purely research components of the work and applying local salaries. This calculation assumed that all resources are fully used, with no spare capacity. The full cost of the operation was assessed at USD 85.4 per km2, of which USD 55.7 or 65.2% were field costs, made up of three component activities (target deployment: 34.5%, trap monitoring: 10.6% and target maintenance: 20.1%). The remaining USD 29.7 or 34.8% of the costs were for preliminary studies and administration (tsetse surveys: 6.0%, sensitisation of local populations: 18.6% and office support: 10.2%). Targets accounted for only 12.9% of the total cost, other important cost components were labour (24.1%) and transport (34.6%). Discussion Comparison with the updated cost of historical HAT vector control projects and recent estimates indicates that this work represents a major reduction in cost levels. This is attributed not just to the low unit cost of tiny targets but also to the organisation of delivery, using local labour with bicycles or motorcycles. Sensitivity analyses were undertaken, investigating key prices and assumptions. It is believed that these costs are generalizable to other HAT foci, although in more remote areas, with denser vegetation and fewer people, costs would increase, as would be the case for other tsetse control techniques