Five New Species of Guimaraesiella (Phthiraptera: Ischnocera) from Broadbills (Aves: Passeriformes: Calyptomenidae: Eurylaimidae)

Under embargo until: 2020-11-15Five new species of Guimaraesiella Eichler, 1949 are described and illustrated from hosts in the Eurylaimidae and Calyptomenidae. They are Guimaraesiella corydoni n. sp. from Corydon sumatranus laoensisMeyer de Schauensee, 1929; Guimaraesiella latirostris n. sp. from Eurylaimus ochromalusRaffles, 1822; Guimaraesiella cyanophoba n. sp. from Cymbirhynchus macrorhynchus malaccensisSalvadori, 1874 and C. m. siamensisMeyer de Schauensee and Ripley, 1940; Guimaraesiella altunai n. sp. from Calyptomena viridis caudacutaSwainson, 1838; and Guimaraesiella forcipata n. sp. from Eurylaimus steerii steeriiSharpe, 1876. These represent the first species of Guimaraesiella described from the Calyptomenidae and Eurylaimidae, as well as the first species of this genus described from the Old World suboscines.acceptedVersio

Coexistence of multiple sclerosis and brain tumours: Case report and review

In the present report, a review of the literature on the combination of multiple sclerosis and brain tumours is performed. Additionally, the frequency of such combination, possible etiopathogenetic mechanisms, current diagnostic criteria and treatment approaches are reviewed. Furthermore, the case of a 30-year-old man with multiple sclerosis and anaplastic astrocytoma of the right temporal lobe is described in detail. Specifically, the patient underwent a series of tests, including laboratory analyses of blood and cerebrospinal fluid, brain MRI in various modes, MR spectroscopy and excised tumour’s pathohistological and immunohistochemical examination. Results of the tests are reported here. A staged examination and treatment of the patient allowed the researchers to perform a correct diagnosis and obtain a satisfactory functional outcome

Сайты федеральных библиотек: состояние и перспективы развития с точки зрения поисковой оптимизации

The www-sites represent libraries virtually on the Internet and perform many of the functions of these institutions. Currently, library site building is developing intensively. The researchers focus on the organization and content allocation, design concept, services marketing, assessment of information resources quality. One of the most important tasks to be solved by these social institutions is user acquisition. However, the issues of search engine optimization of www-sites are studied insufficiently. The author presents the findings of the study of federal libraries’ www-sites. The comparative analysis of www-sites was carried out by the criteria of www-site quality index, number of external links to the resource, total social activity, as well as the adaptability for mobile devices. The PR-CY.ru service was used as an analysis tool. According to the study, the one third of the federal libraries’ www-sites can be characterized, from the user's point of view, as high-quality information resources. The author also analyzes the information channels through which users get to the federal libraries www-sites. For 80% of www-sites under examination, the largest number of users find them with search engines. Only 40% of the federal libraries’ sites are adapted for mobile devices, which affects the quality of information resources and makes it difficult for users to access information. The author emphasizes the need for optimizing the www-sites of federal libraries, as well as for monitoring their information resources using web-analytics.Сайты являются виртуальными представительствами библиотек и выполняют ряд их функций. В настоящее время библиотечное сайтостроение активно развивается. Внимание исследователей сосредоточено на организации и размещении контента, концепции дизайна, маркетинге предлагаемых сервисов, оценке качества информационных ресурсов. Одна из важнейших задач – привлечение пользователей на свой информационный ресурс. Однако вопросам оптимизации сайтов под поисковые системы в профессиональной литературе уделяется недостаточное внимание. В статье отражены результаты исследования сайтов федеральных библиотек с точки зрения их поисковой оптимизации. Сравнительный анализ проведён по таким критериям, как индекс качества сайта, количество внешних ссылок на ресурс, общая социальная активность, а также адаптивность сайта для мобильных устройств. В качестве инструмента анализа использовался сервис PR-CY.ru. Исследование показало, что треть сайтов федеральных библиотек можно охарактеризовать как качественные информационные ресурсы. Проведён анализ информационных каналов, по которым пользователи попадают на сайты федеральных библиотек: на 80% анализируемых сайтов большинство приходит из поисковых систем. Отмечено, что для мобильных устройств оптимизированы лишь 40% сайтов федеральных библиотек, что сказывается на качестве информационных ресурсов и затрудняет доступ к информации. В статье подчёркнуты необходимость оптимизации сайтов федеральных библиотек и проведения мониторинга их информационных ресурсов средствами веб-аналитики

Федеральные библиотеки в виртуальном пространстве: анализ состояния и перспективы деятельности

Abstract: The findings of monitoring virtual space of federal libraries: their websites and social media, are interpreted. The author analyzes search optimization indicators, i. e. website quality factor, website adaptiveness for mobile systems, as well as behavior indicators, e.g. average visit time, number of viewed pages per visit, etc. The comparison of these findings with prior research evidences on increasing quality of information resources under investigation. The efficiencyоf the federal libraries’ activity in VKontakte (VK), one of the most popular mass media and digital platforms, was analyzed with Socstat.ru web-analytics. The federal libraries’ VK communities are characterized by: number of subscribers, total number of posts, number of posts for a time period, average post length, and the average number of posts per day. Federal library user activity factors areal so analyzed; number of responses, average number of responses, average community engagement, and average post engagement. The author insists on the necessity of monitoring of library presence in the digital environment through web-analytics for libraries efficient integration into the single cultural information space.Аннотация: Представлены результаты мониторинга виртуального пространства федеральных библиотек: сайтов и социальных сетей. Проанализированы такие показатели поисковой оптимизации, как индекс качества сайтов, их адаптивность под мобильные системы, а также поведенческие показатели: среднее время пребывания на сайте, количество просмотренных страниц за визит и др. Сравнение результатов исследования поисковой оптимизации с проведёнными ранее свидетельствует о повышении качества рассматриваемых информационных ресурсов. Проведён анализ эффективности работы федеральных библиотек в социальной сети «ВКонтакте» как одной из наиболее популярных цифровых платформ. В качестве средства веб-аналитики использовался сервис Socstat.ru. Дана общая характеристика сообществ «ВКонтакте» для федеральных библиотек, включающая такие показатели, как число подписчиков, общее число постов; количество постов, добавленных за определённый период; средний охват поста, а также среднее количество добавленных постов в день. Проанализированы показатели активности пользователей федеральных библиотечных учреждений «ВКонтакте»: количество реакций, среднее количество реакций, средняя вовлечённость по сообществу и по посту. Автор отмечает необходимость мониторинга представительств библиотек в цифровой среде средствами веб-аналитики для их эффективной интеграции в единое культурное информационное пространство

The main issues of quality assurance of radiopharmaceuticals

One of the prerequisites for successful application of nuclear medicine technologies is the production and clinical use of radiopharmaceuticals (RPs) of a reliably high quality. The aim of the review is to discuss specific properties of RPs, which stipulate specific approaches to their production (or preparation) and quality control. The decisive requirement for the management of RPs at all stages of their life cycle is the observance of the radiation safety rules and regulations. The paper considers the main approaches to assessing the risks of medical radiation exposure to patients and radiation protection of nuclear medicine staff. The choice of a particular quality parameter and the corresponding analytical procedure should be made taking into account the duration of the test, which, like the production time, should be comparable with the radionuclide half-life. The feasibility of the analytical procedure should also be taken into account, given the high radioactivity of the samples tested. Now that theranostics has caught on, new approaches are being developed all over the world concerning regulatory aspects of transition from preclinical studies of RPs to clinical trials, because, according to experts, this is becoming a key condition for rapid implementation of nuclear medicine achievements. The results and conclusions of the present study can be used in the development and expert review of monographs and other specifications required for RP marketing and use. The results of the analysis suggest that it is necessary to develop specific requirements and guidelines for RP testing and evaluation for their successful promotion on the EAEU market

Application of Data Mining and Process Mining approaches for improving e-Learning Processes

The paper describes the basic principles of Data mining and Process mining methods, their similarities and differences. Some examples of special software for Data mining and Process mining are presented. The authors examine the research in Educational Data Mining field, associated with the use of Data mining techniques in education, give examples of problems to be solved with the use of Data mining and Process mining techniques in the area of traditional and e-learning, describe the possibilities and limitations of different methods. A review of major scientific conferences and journals devoted to the research in Educational Data Mining is made.This work is supported by the Bulgarian National Scientific Research Fund under the contract DFNI - I02/13

The role of subprocess-connector in business process modeling

The paper presents several aspects of Petri Nets as a tool for surmounting the deadlocks in a system. Emphasis is placed on the importance of the correct and consistent business process planning. The most important objective in business process generation is the proper execution of the activities in a business organization and studying the links between them. To visualize all business processes in a system a subprocess – connector has been created that helps to detect: the deadlock markings in a system. It is impossible to change a component without interfering the operation with the others.This work is supported by the Bulgarian National Scientific Research Fund under the contract DFNI - I02/13

Applying process mining techniques and neural networks to creating and assessment of business process models

The article presents an approach for automated generation of business process models by applying process mining techniques to event logs created during the operation of information systems used in an organization. Existing algorithms for process mining are discussed. Criteria for performing a comparative analysis of these algorithms are specified. А framework is proposed in which to build and analyze business process models. The framework includes tools for initial analysis of the event log file, extracting elements of a business process model, and composing a new model by applying a trained neural network

Association between Arg753Gln (rs574308) polymorphism of the Toll-like receptor 2 (TLR2) gene and the risk of pulmonary sarcoidosis among the residents of Karelia”

Genetic factors play an important role in the development and progression of many disorders including lung sarcoidosis which is a systemic inflammatory granulomatous disease of unknown etiology, characterized by the formation of epithelioid cell granules in affected tissues. Intensity of the developing inflammation may partially depend on genetic factors which may influence both susceptibility to lung sarcoidosis, and also clinical course of the disease and the degree of inflammatory response from the immune system. Allelic polymorphism of distinct genes is therefore worth of study. In the carriers of certain allele variants, one may observe either increase, or a decreased production of pro-inflammatory factors. Among the candidate factors involved in higher susceptibility of humans, one may consider Toll-like receptors (TLRS) which may contribute to formation of granulomas. Relevant data concerning association between the allele variants of these genes and susceptibility to lung sarcoidosis, and its clinical course are still quite limited and contradictory. The aim of the present study was to analyze the association between the Arg753Gln (rs574308) polymorphism of the Toll-like receptor 2 (TLR2) gene and the risk of developing pulmonary sarcoidosis.A total of 253 persons were under study including 122 patients diagnosed with morphologically verified sarcoidosis with lung involvement (average age, 41.00±12.56 years), and 131 healthy donors comprising a control group (average age, 44.00±14.23 years). The distribution of alleles and genotypes for the Arg753Gln (rs574308) polymorphic TLR2 gene marker was studied in the groups of patients with pulmonary sarcoidosis and healthy donors. The test alleles of this polymorphic marker were typed by means of PCR technique followed by length analysis restriction fragments (PCR-RFLP method).There were no statistically significant differences in the distribution of allele and genotype frequencies for the polymorphic marker Arg753Gln (rs574308) of the TLR2 gene between the control group and the group of patients with pulmonary sarcoidosis: χ2 = 2.0, df = 1, p = 0.158 and χ2 = 2.19, df = 2, p = 0.140, respectively.The polymorphic marker Arg753Gln (rs574308) of Toll-like receptor 2 gene is not associated with the risk of developing pulmonary sarcoidosis among ethnic Russians of the Republic of Karelia