Technology development of obtaining essential fatty acids from hydrobionts hydrolyzates

Articleɷ-3, 6-fatty acids from hydrobiontsare a minor component in the nutrition of European countries population. This causes a number of diseases, such as cardiovascular ones, cancer etc. There is a task of concentrating these acids in oil due to the fact that to meet their daily needs it is problematic to use large quantities of fish oil-from 15 to 20 g. Particularly rich in ɷ-3, 6-acids are wastes from the cutting of hydrobionts, containing muscle tissue and skin. Protein hydrolysates were obtained from rainbow trout (Oncorhynchusmykiss) and Atlantic herring (Clupeaharengus) wastes by the electrochemical method using electrolyzers of the original design which are allowed to be used in food industry. A technological scheme of separating of lipids from protein hydrolyzates has been developed and experimental batches of oil samples have been developed. To concentrate the fatty acids the cryoconcentration method was used. The phase transitions of the obtained lipids were studied after their cryoconcentration in the temperature range from + 15 °C to minus 40 °C in the environment of calcium chloride using a low-temperature refrigeration unit. To analyze phase transitions the plant was used, which is a container with a solution of calcium chloride cooled by a low-temperature refrigeration machine. The properties of 5 fractions of lipids formed at the time of lipid phase transitions have been identified and studied (the fractional composition, acid, iodine numbers, the content of polyunsaturated fatty acids (PUFAs), vitamin D3 and A). It was established that as cryoconcentration increases the concentration of PUFAs, reaching values close to 90%, which allows the resulting product to be attributed to biologically active food additives (BAA). By calculation, it was shown that to create functional food products on fish base from fish of the Gadidae family it is enough to inject 4 grams of BAA to 100 grams of the product. Organoleptic properties of food products from low-fat fish species were improved

Acceleration and transport of ions in turbulent current sheets: formation of non-maxwelian energy distribution

The paper is devoted to particle acceleration in turbulent current sheet (CS). Our results show that the mechanism of CS particle interaction with electromagnetic turbulence can explain the formation of power law energy distributions. We study the ratio between adiabatic acceleration of particles in electric field in the presence of stationary turbulence and acceleration due to electric field in the case of dynamic turbulence. The correlation between average energy gained by particles and average particle residence time in the vicinity of the neutral sheet is discussed. It is also demonstrated that particle velocity distributions formed by particle-turbulence interaction are similar in essence to the ones observed near the far reconnection region in the Earth's magnetotail

La detección de las diferencias psicológicas individuales de los españoles nativos y los inmigrantes de Marruecos, basándose las pruebas de control propioceptivo en el rendimiento motor fino

Background: Russian physiologists and psychologists posed the questions of the levels of psychic regulation of the temperament, character and personality (Anan’ev, 1980; Nebylitsin, 1966; Pavlov, 1951; Teplov, 1963). The aim of our study was to observe the differences due to both --- cultural nature and individual changes in personality --- relevant to adjustment mechanisms in Arabic migrants in Spain. Method: Proprioceptive Diagnostics of Temperament and Character (DP-TC, Tous Ral et al., 2012) was used to obtain observations in fine motor performance in two groups: immigrants from Morocco to Spain and Spaniards. The DP-TC of individual and personality differences is based on fine motor precision tasks and allows comparing performances of participants from different cultures with no bias of linguistic interpretation. Results: The significant differences in fine motor performance (proprioceptive condition) were found in average group’s results. The consequent interpretation of their personality and indi-vidual behavioural differences was realised as per the DP-TC test dimensions. The results are discussed in terms of the interplay between possible cultural and individual differences concerning changes, related to the adjustment in migration processes. Antecedentes: Los fisiólogos y psicólogos rusos plantearon las cuestiones de los niveles de regu-lación psíquica del temperamento, el carácter y la personalidad (Pavlov, 1951; Anan’ev, 1980;Teplov, 1966; Nebylitsin, 1966). El objetivo de nuestro estudio fue observar las diferenciasdebidas tanto a la naturaleza cultural como a los cambios individuales en la personalidad,relevantes en los mecanismos de ajuste en los migrantes.Método: Se utilizó el Diagnóstico Propioceptivo del Temperamento y del Carácter (DP-TC, Touset al., 2012) para obtener observaciones en el rendimiento motor fino en 2 grupos: inmigrantesde Marruecos a Espa˜na y espa˜noles. El DP-TC se basa en tareas de precisión motora fina y permitecomparar las actuaciones de participantes de diferentes culturas sin sesgo de interpretaciónlingüística.Resultados: Se encontraron las diferencias significativas en el rendimiento (condición pro-pioceptiva) según los resultados promedios de los grupos. Se realizó la correspondienteinterpretación de las diferencias en personalidad. Los resultados se discuten en términos de lainteracción entre las posibles diferencias culturales e individuales relacionadas con el ajusteen los procesos migratorios.Conclusión: Los rasgos de temperamento relacionados con la asertividad en los migrantes seencontraron bajos junto con diferencias culturales en variabilidad de comportamiento y estilode atención

Variability of Cerebral Deep Venous System in Preterm and Term Neonates Evaluated on MR SWI Venography

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Oxidative stress as a primary risk factor for brain damage in preterm newborns

The risk of oxidative stress is high in preterm newborns. Room air exposure of an organism primed to develop in a hypoxic environment, lacking antioxidant defenses, and subjected to hyperoxia, hypoxia, and ischemia challenges the newborn with oxidative stress production. Free radicals can be generated by a multitude of other mechanisms, such as glutamate excitotoxicity, excess free iron, inflammation, and immune reactions. Free radical-induced damage caused by oxidative stress appears to be the major candidate for the pathogenesis of most of the complications of prematurity, brain being especially at risk, with short to long-term consequences. We review the role of free radical oxidative damage to the newborn brain and propose a mechanism of oxidative injury, taking into consideration the particular maturation-dependent vulnerability of the oligodendrocyte precursors. Prompted by our observation of an increase in plasma Adenosine concentrations significantly associated with brain white matter lesions in some premature infants, we discuss a possible bioenergetics hypothesis, correlated to the oxidative challenge of the premature infant. We aim at explaining both the oxidative stress generation and the mechanism promoting the myelination disturbances. Being white matter abnormalities among the most common lesions of prematurity, the use of Adenosine as a biomarker of brain damage appears promising in order to design neuroprotective strategies

Magnetic configurations of the tilted current sheets in magnetotail

In this research, the geometrical structures of tilted current sheet and tail flapping waves have been analysed based on multiple spacecraft measurements and some features of the tilted current sheets have been made clear for the first time. The geometrical features of the tilted current sheet revealed in this investigation are as follows: (1) The magnetic field lines (MFLs) in the tilted current sheet are generally plane curves and the osculating planes in which the MFLs lie are about vertical to the equatorial plane, while the normal of the tilted current sheet leans severely to the dawn or dusk side. (2) The tilted current sheet may become very thin, the half thickness of its neutral sheet is generally much less than the minimum radius of the curvature of the MFLs. (3) In the neutral sheet, the field-aligned current density becomes very large and has a maximum value at the center of the current sheet. (4) In some cases, the current density is a bifurcated one, and the two humps of the current density often superpose two peaks in the gradient of magnetic strength, indicating that the magnetic gradient drift current is possibly responsible for the formation of the two humps of the current density in some tilted current sheets. Tilted current sheets often appear along with tail current sheet flapping waves. It is found that, in the tail flapping current sheets, the minimum curvature radius of the MFLs in the current sheet is rather large with values around 1 <I>R<sub>E</sub></I>, while the neutral sheet may be very thin, with its half thickness being several tenths of <I>R<sub>E</sub></I>. During the flapping waves, the current sheet is tilted substantially, and the maximum tilt angle is generally larger than 45°. The phase velocities of these flapping waves are several tens km/s, while their periods and wavelengths are several tens of minutes, and several earth radii, respectively. These tail flapping events generally last several hours and occur during quiet periods or periods of weak magnetospheric activity

Early Pain Exposure Influences Functional Brain Connectivity in Very Preterm Neonates

Background: Early exposure to nociceptive events may cause brain structural alterations in preterm neonates, with long-lasting consequences on neurodevelopmental outcome. Little is known on the extent to which early pain may affect brain connectivity. We aim to evaluate brain functional connectivity changes in preterm neonate that underwent multiple invasive procedures during the postnatal period, and to correlate them with the neurodevelopmental outcome at 24 months. Methods: In this prospective case-control study, we collected information about exposure to painful events during the early postnatal period and resting-state BOLD-fMRI data at term equivalent age from two groups of preterm neonate: 33 subjected to painful procedures during the neonatal intensive care (mean gestational age 27.9 \ub1 1.8 weeks) and 13 who did not require invasive procedures (average gestational age 31.2 \ub1 2.1 weeks). A data-driven principal-component-based multivariate pattern analysis (MVPA) was used to investigate the effect of early pain exposure on brain functional connectivity, and the relationship between connectivity changes and neurodevelopmental outcome at 24 months, assessed with Griffiths, Developmental Scale-Revised: 0\u20132. Results: Early pain was associated with decreased functional connectivity between thalami and bilateral somatosensory cortex, and between the right insular cortex and ipsilateral amygdala and hippocampal regions, with a more evident effect in preterm neonate undergoing more invasive procedures. Functional connectivity of the right thalamocortical pathway was related to neuromotor outcome at 24 months (P = 0.003). Conclusion: Early exposure to pain is associated with abnormal functional connectivity of developing networks involved in the modulation of noxious stimuli in preterm neonate, contributing to the neurodevelopmental consequence of preterm birth