257 research outputs found

    The Suaineadh Project : a stepping stone towards the deployment of large flexible structures in space

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    The Suaineadh project aims at testing the controlled deployment and stabilization of space web. The deployment system is based on a simple yet ingenious control of the centrifugal force that will pull each of the four daughters sections apart. The four daughters are attached onto the four corners of a square web, and will be released from their initial stowed configuration attached to a central hub. Enclosed in the central hub is a specifically designed spinning reaction wheel that controls the rotational speed with a closed loop control fed by measurements from an onboard inertial measurement sensor. Five other such sensors located within the web and central hub provide information on the surface curvature of the web, and progression of the deployment. Suaineadh is currently at an advanced stage of development: all the components are manufactured with the subsystems integrated and are presently awaiting full integration and testing. This paper will present the current status of the Suaineadh project and the results of the most recent set of tests. In particular, the paper will cover the overall mechanical design of the system, the electrical and sensor assemblies, the communication and power systems and the spinning wheel with its control system

    Polarografía oscilográfica de la sal sódica del 1,2-benzisoziatol-3-(2H)-ona 1,1 dióxido

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    Se ha estudiado la reducción electroquímica del 1,2-Bencisotiazol-3-(2H)-ona 1,1 dióxido sobre electrodo de gota de mercurio. Los datos oscilopolarográficos ponen de manifiesto que el producto de la reacción catódica se adsorbe intensamente sobre la superficie del electrodo indicador.The electrochemical reduction of 1,2,-Benzisothiazol-3-(2H)-one 1,1 dioxide in the dropping Hg electrode is studied. Oscillopolarographic data reveal that the products of the catodics reaction is strongly adsorbed at the mercury drop

    Polarografía convencional de la sal sódica del 1,2-bencisotiazol-3-(2H)-Ona 1,1 Dioxo

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    lt has been s tudied electrochemi cal reduction of 1,2-Benzisothiazol-3-(2H)one 1,1 dioxide in aqueous medium on the dropping mercury electrode. Polarographic data show one well defined reduction step.Se ha estudiado la reducción eletroquímica del 1,2 Bencisotiazol-3-(2H)-ona 1,1 dióxido en medio acuoso sobre el electrodo de gota de mercurio. Los datos polarográficos ponen de manifiesto un paso de reducción bien definido

    Determinación cuantitativa de la sal sódica del 1,2-bencisotiazol-3-(2H)-ona dióxido en muestras comerciales

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    It has been studied the quantitative determination of 1,2-bencisotiazol-3-(2H)-one 1,1 dioxide in commercial products, by conventional polarography using the addition method.Se ha estudiado la determinación cuantitativa del 1,2-bencisotiazol-3-(2H)-ona 1, 1 dióxido en formas comerciales por polarografía convencional aplicando el método de adición

    Polarografía convencional de la sal sódica del 1,2-bencisotiazol-3-(2H)-Ona 1,1 Dioxo

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    Se ha estudiado la reducción eletroquímica del 1,2 Bencisotiazol-3-(2H)-ona 1,1 dióxido en medio acuoso sobre el electrodo de gota de mercurio. Los datos polarográficos ponen de manifiesto un paso de reducción bien definido.lt has been studied electrochemical reduction of 1,2-Benzisothiazol-3-(2H)one 1,1 dioxide in aqueous medium on the dropping mercury electrode. Polarographic data show one well defined reduction step

    Determinación cuantitativa de la sal sódica del 1,2-bencisotiazol-3-(2H)-ona dióxido en muestras comerciales

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    Se ha estudiado la determinación cuantitativa del 1,2-bencisotiazol-3-(2H)-ona 1, 1 dióxido en formas comerciales por polarografía convencional aplicando el método de adición.It has been studied the quantitative determination of 1,2-bencisotiazol-3-(2H)-one 1,1 dioxide in commercial products, by conventional polarography using the addition method

    Ambient particulate pollution and the world-wide prevalence of asthma, rhinoconjunctivitis and eczema in children: Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC)

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    Objectives: To investigate the effect of ambient particulate matter on variation in childhood prevalence of asthma, rhinoconjunctivitis and eczema. Methods: Prevalences of asthma, rhinoconjunctivitis and eczema obtained in Phase One of the International Study of Asthma and Allergies in Childhood (ISAAC) were matched with city-level estimates of residential PM10 obtained from a World Bank model. Associations were investigated using binomial regression adjusting for GNP per capita and for clustering within country. For countries with more than one centre, a two stage meta-analysis was carried out. The results were compared with a meta-analysis of published multi-centre studies. Results: Annual concentrations of PM₁₀ at city level were obtained for 105 ISAAC centres in 51 countries. After controlling for GNP per capita, there was a weak negative association between PM₁₀ and various outcomes. For severe wheeze in 13-14-year-olds, the OR for a 10 μg/m³ increase in PM₁₀ was 0.92 (95 CI 0.84 to 1.00). In 24 countries with more than one centre, most summary estimates for within-country associations were weakly positive. For severe wheeze in 13-14-year-olds, the summary OR for a 10 μg/m³ increase in PM₁₀ was 1.01 (0.92 to 1.10). This result was close to a summary OR of 0.99 (0.91 to 1.06) obtained from published multi-centre studies. Conclusions: Modelled estimates of particulate matter at city level are imprecise and incomplete estimates of personal exposure to ambient air pollutants. Nevertheless, our results together with those of previous multi-centre studies, suggest that urban background PM₁₀ has little or no association with the prevalence of childhood asthma, rhinoconjunctivitis or eczema either within or between countries

    The Global Asthma Network rationale and methods for Phase I global surveillance: prevalence, severity, management and risk factors.

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    The Global Asthma Network (GAN), established in 2012, followed the International Study of Asthma and Allergies in Childhood (ISAAC). ISAAC Phase One involved over 700 000 adolescents and children from 156 centres in 56 countries; it found marked worldwide variation in symptom prevalence of asthma, rhinitis and eczema that was not explained by the current understanding of these diseases; ISAAC Phase Three involved over 1 187 496 adolescents and children (237 centres in 98 countries). It found that asthma symptom prevalence was increasing in many locations especially in low- and middle-income countries where severity was also high, and identified several environmental factors that required further investigation.GAN Phase I, described in this article, builds on the ISAAC findings by collecting further information on asthma, rhinitis and eczema prevalence, severity, diagnoses, asthma emergency room visits, hospital admissions, management and use of asthma essential medicines. The subjects will be the same age groups as ISAAC, and their parents. In this first global monitoring of asthma in children and adults since 2003, further evidence will be obtained to understand asthma, management practices and risk factors, leading to further recognition that asthma is an important non-communicable disease and to reduce its global burden

    Asthma in changing environments - chances and challenges of international research collaborations between South America and Europe - study protocol and description of the data acquisition of a case-control-study

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    <p>Abstract</p> <p>Background</p> <p>Asthma in children is an emerging public health problem in South America. So far, research in this part of the world is limited. This paper presents the methodology and description of the data acquisition of an asthma case-control study conducted in the Central South of Chile.</p> <p>Methods/Design</p> <p>A hospital-based case-control study about asthma (188 cases, 294 controls) in children (6-15 years) was carried out in Valdivia, Chile between November 2008 and December 2009. Data on asthma risk factors were collected by computer-assisted personal interview using validated questions from e.g. ISAAC phase II. Data on household dust exposure (endotoxin, allergen analyses), skin prick tests to most common allergens, stool examinations for parasitic infection, and blood samples (total IgE, genetics) were collected. Additionally, 492 randomly chosen blood donors were recruited in order to assess allele frequencies in the population of Valdivia.</p> <p>Discussion</p> <p>Overall 1,173 participants were contacted. Response was 82% among cases and 65% among controls. Atopic sensitization was high (78% among cases, 47% among controls). Cases had a statistically significantly (p < .0001) increased self-reported 12-month prevalence of symptoms of rhinitis (82% vs. 51%) and wheeze (68% vs. 16%). The study is well placed to address current hypotheses about asthma and its correlates in the South American context. Results of this study might help develop novel, innovative and individualized prevention strategies in countries in transition with respect to the South American context.</p

    Components of a Neanderthal gut microbiome recovered from fecal sediments from El Salt

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    A comprehensive view of our evolutionary history cannot ignore the ancestral features of our gut microbiota. To provide some glimpse into the past, we searched for human gut microbiome components in ancient DNA from 14 archeological sediments spanning four stratigraphic units of El Salt Middle Paleolithic site (Spain), including layers of unit X, which has yielded well-preserved Neanderthal occupation deposits dating around 50 kya. According to our findings, bacterial genera belonging to families known to be part of the modern human gut microbiome are abundantly represented only across unit X samples, showing that well-known beneficial gut commensals, such as Blautia, Dorea, Roseburia, Ruminococcus, Faecalibacterium and Bifidobacterium already populated the intestinal microbiome of Homo since as far back as the last common ancestor between humans and Neanderthals.Results and discussion - Ancient DNA sequencing and damage assessment. - Detection of ancient human mitochondrial DNA. - Profiling of ancient prokaryotic DNA. - Putative components of the Neanderthal gut microbiome. Methods - Site and sampling. - Ancient DNA extraction. - Library preparation and sequencing. - Bioinformatics analysis. - Independent validation of taxonomic assignments. - mtDNA analysis and contamination estimate. - Statistics and reproducibility
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