Personality traits distinguishing dementia with Lewy bodies from Alzheimer disease

This is the publisher's version, also available electronically from http://www.neurology.org/content/68/22/1895.Objective: To identify personality traits that distinguish dementia with Lewy bodies (DLB) from Alzheimer disease (AD). Methods: We examined 290 participants enrolled in a longitudinal study (nondemented control = 34, DLB = 128, AD = 128) followed to autopsy. As part of the annual interview with the collateral source, the clinician asked about specific changes in personality, interests, and drives based on items from the Blessed Dementia Scale (BDS). Statistical analysis was performed using χ2 and Fisher exact tests. Factor analysis was performed to determine underlying structure and receiver operating characteristic curves assessed the ability for each of three derived factors to discriminate DLB from AD. Results: The sample was evaluated for a mean of 4.8 visits (range 1 to 14) with a mean age of 77.6 ± 9.9 years. The participants' cognitive status ranged from nondemented (Clinical Dementia Rating [CDR] 0) through all stages of dementia (CDR ≥ 0.5). Personality traits that distinguished DLB included diminished emotional responsiveness (p = 0.004), relinquishing hobbies (p = 0.01), growing apathy (p = 0.03), and purposeless hyperactivity (p = 0.003). Factor analyses of the BDS revealed a PASSIVE factor (diminished emotional responsiveness, relinquished hobbies, growing apathy, and purposeless hyperactivity) explaining 10.4% of variance and that DLB was more likely to manifest these personality traits than AD (p = 0.001). The PASSIVE factor discriminated DLB from AD (area under the curve = 0.61, 95% CI: 0.54 to 0.68, p = 0.006). Any change in personality is associated with the presence of visual hallucinations. Conclusions: Our results suggest that incorporating a brief, simple inventory of personality traits may improve the identification of individuals with dementia with Lewy bodies

The Golden Age of European Cabaret

Program for the second annual RISD Cabaret held in the Cellar in the Pit. Design and layout by Anne Johnson, Susan Sellers and Georgie Stout.https://digitalcommons.risd.edu/liberalarts_cabaret_programs/1001/thumbnail.jp

From St. Petersburg to Krushchev\u27s Boot

Program for the first annual RISD Cabaret held in Memorial Hall. Design and layout by Justin Kerr.https://digitalcommons.risd.edu/liberalarts_cabaret_programs/1000/thumbnail.jp

Biomedical colonialism or local autonomy?: local healers in the fight against tuberculosis

Analiza el papel de los agentes médicos autóctonos y sus conocimientos en las campañas antituberculosas contemporáneas en el África subsahariana. Sitúa la medicina contemporánea, llevada a cabo en África en la herencia cultural de la medicina colonial, para comprender el marco histórico en el que se desarrollaron, a partir de los años setenta del siglo XX, las estrategias de la Organización Mundial de la Salud de promoción y desarrollo de las medicinas 'tradicionales'. En los proyectos sanitarios analizados, se evalúan las prácticas médicas locales y se entrenan a los agentes autóctonos para integrarlos en actividades estrictamente biomédicas: identificación de síntomas, remisión a hospitales o supervisión de tratamientos farmacológicos.The article explores the role played by indigenous medical agents, and their knowledge, within contemporary tuberculosis campaigns in sub-Saharan Africa. To understand the historical framework within which the World Health Organization devised its strategies to promote and develop traditional medicine as of the 1970s, the article contextualizes contemporary medicine as a cultural legacy of colonial medicine. Under the public healthcare projects analyzed in the article, local medical practices were assessed and indigenous agents trained so they could take part in strictly biomedical activities, like symptom identification, referrals to hospitals, or supervision of drug treatments.Trabajo realizado para la obtención del Diploma de Estudios Avanzados (DEA) en el programa de doctorado Salud: Antropología e Historia, bajo la dirección de la profesora Rosa María Medina Doménech

Are substrate choices by minnows within a glide determined by food availability?

Data collected shows that food availability does not provide a reason for minnow microdistribution. However, the microhabitat distribution of minnows in the glide is associated with the presence of structural refuges attributed to the risk of predation. Schlosser's macrohabitat observations of predators in the pool forcing minnows into the glide can also be applied to the microhabitat scale.http://deepblue.lib.umich.edu/bitstream/2027.42/54681/1/3121.pdfDescription of 3121.pdf : Access restricted to on-site users at the U-M Biological Station

Status of the recovery mandate under section 7(a)(1) of the U.S. Endangered Species Act

The U.S. Endangered Species Act (ESA) is widely considered to be one of the strongest laws for 10 protecting imperiled wildlife, with nearly all species protected under the law still existing today. 11 Among the ESA’s strongest provisions, at least as written, is the requirement under section 7(a)(1) 12 that federal agencies use their authorities to help recover imperiled species. New initiatives like 13 30x30, the campaign to conserve at least thirty percent of U.S. lands and waters by 2030, offer 14 opportunities to reinvigorate and expand 7(a)(1) programs to play a significant role in biodiversity 15 conservation. To gauge the current status of 7(a)(1) plans and assess their effectiveness, we collected 16 all section 7(a)(1) materials available to the public through internet searches and direct requests to 17 agencies. We evaluated the scope of existing 7(a)(1) programs and found that despite the clear 18 potential benefits of strong programs, the section has been significantly underused by federal 19 agencies. Further, we show that existing plans are highly inconsistent in content and style, and we 20 trace that inconsistency to the lack of policy guidance for their creation and implementation. Based 21 on these findings, we recommend five strategies for improving 7(a)(1) implementation: establishment 22 of formal guidance from the federal wildlife agencies, tailored guidance from other federal agencies 23 to help them meet their 7(a)(1) obligation, dedicated funding, integration of 7(a)(1) into existing 24 initiatives and opportunities, and top-level executive branch coordination and cooperation

Long‐term increases in shell thickness in Elliptio complanata (Bivalvia: Unionidae) in the freshwater tidal Hudson River

The shells of freshwater molluscs are highly plastic in response to environmental and ecological conditions, which can affect ecological interactions and ecosystem functioning.We tested for changes in relative shell thickness in the unionid bivalve Elliptio complanata in the freshwater tidal Hudson River over 1991–2017, a period of changing water chemistry and predation pressure.Shells of both juveniles (shells <20 mm long) and larger animals became substantially (c. 10%–25%) and significantly heavier (for a given shell length) over the study period. This parallels previously published results for the non‐native zebra mussel Dreissena polymorpha in the Hudson.Increased shell thickness during the study period could be explained by rising pH, alkalinity, and temperature, which increased calcite saturation and favoured the precipitation of calcium carbonate shells, as well as a response to greater predation by shell‐crushing predators.Because the factors that affect shell thickness (e.g. calcium carbonate saturation and presence and abundance of predators) are changing rapidly in many lakes and rivers, similar large changes in shell thickness may be occurring in fresh waters around the world, affecting ecological interactions and ecosystem functioning.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/168269/1/fwb13723_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/168269/2/fwb13723.pd

Appendix A. Detailed information about the study sites (locations, crayfish densities, environmental conditions, and interannual variability).

Detailed information about the study sites (locations, crayfish densities, environmental conditions, and interannual variability)

Flutter and vibration analysis by a modal method : analytical development and computational procedure /

A modal solution of the flutter and vibration problems for a multiple component system is presented. The formulation requires the aerodynamic characteristics in the form of aerodynamic influence coefficients, and the structural and inertial characteristics in the form of free vibration modes and frequencies and a mass matrix for each component. The use of a rigid-body modal matrix permits a general analysis for a system free in space with up to six rigid-body degrees of freedom. The solution also utilized a newly developed subroutine for finding the eigenvalues and eigenvectors of a non-Hermitian matrix having close roots, and obtains the corresponding values of frequency, required structural damping, and velocity of the flutter system. The Aerospace IBM 7090 Computer Program No. LD014A provides the flutter or vibration solution for a system composed of as many as 20 flexible components, each of which may have up to 50 control points. The solution is carried out by a modal (series) method choosing a series of up to 40 cantilever and/or free-free vibration modes to approximate and control point deflections. The program may be used to find the vibration characteristics of a composite system if the cantilever vibration characteristics of the components are known. (Author)."31 July 1963."Includes bibliographic references (page 17).A modal solution of the flutter and vibration problems for a multiple component system is presented. The formulation requires the aerodynamic characteristics in the form of aerodynamic influence coefficients, and the structural and inertial characteristics in the form of free vibration modes and frequencies and a mass matrix for each component. The use of a rigid-body modal matrix permits a general analysis for a system free in space with up to six rigid-body degrees of freedom. The solution also utilized a newly developed subroutine for finding the eigenvalues and eigenvectors of a non-Hermitian matrix having close roots, and obtains the corresponding values of frequency, required structural damping, and velocity of the flutter system. The Aerospace IBM 7090 Computer Program No. LD014A provides the flutter or vibration solution for a system composed of as many as 20 flexible components, each of which may have up to 50 control points. The solution is carried out by a modal (series) method choosing a series of up to 40 cantilever and/or free-free vibration modes to approximate and control point deflections. The program may be used to find the vibration characteristics of a composite system if the cantilever vibration characteristics of the components are known. (Author).Report prepared by Aerospace Corporation, Laboratories Division, El Segundo, California, for Commander Space Systems Division, United States Air Force, under contract No.Mode of access: Internet