53 research outputs found

    CREATION OF A DIGITAL AFRICAN ARCHIVE

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    Sabinet Gateway, a non-profit organization that promotes and supports library and information services in Africa, has been awarded a $1,8 million grant from the Carnegie Corporation New York to create an African Online Journal Archive. This archive, the first of its kind to contain purely African content, will make academic inputs from all over Africa available for research purposes to local and international organisations and academic institutions. The aim is to create for the first time a central full-text repository of retrospective journal content that contains important African research across a number of fields, including the medical, social sciences and environmental arenas. These materials have unique value, providing not only the vital groundwork for further or related research but assisting to preserve the heritage of the African continent. Stretching over four years, this project includes the sourcing of African journal content, the negotiation of publisher agreements, digitization and indexing of the journal content and the creation of a front end that will make the journal content easily accessible to end users online. As a result the project aims for the archive to contain approximately 90 000 articles

    A National Union Catalog for Shared Cataloging and Resource Sharing by Southern African Libraries

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    The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants.The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants

    CREATION OF A DIGITAL AFRICAN ARCHIVE THROUGH COLLABORATION

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    Sabinet facilitates collaboration between various role players in the African region in an effort to create the most comprehensive collection of African research content in the world. By collaborating with publishers, libraries and faculty at institutions, Sabinet is bringing together full-text content published in journals and institutional repositories, on a single and easily accessible platform. The initiative was started in 1998 with a project to collect and make available African journal content online. The aim was, for the first time, to create a central full-text collection of journal content containing important African research across a number of fields, including medical, social sciences and environmental. In 2007, the project was boosted further when Sabinet was awarded a grant from the Carnegie Corporation of New York to retrospectively digitize and make available an archive of the content of journals that was published prior to the start of the initiative. There are now more than 340 journals available online, containing more than 200 000 articles. Recently, Sabinet has extended collaboration with academic institutions by harvesting and incorporating content published in institutional repositories into the central platform. This collection of unique African research content is now available to local and international organisations. The result of this collaboration has a unique value, providing not only the vital groundwork for further or related research but assisting to preserve the heritage of the African continent whilst at the same time providing valuable world-wide exposure to African publishers

    Innovation management : from a conceptual framework to the design and development of an idea management tool

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    Thesis (MEng)--Stellenbosch University, 2022.ENGLISH SUMMARY: Large corporations are often disrupted by innovative organisations and then they lose their competitive advantage. For organisations to survive today’s competitive marketplace, it is crucial for them to be innovative. Therefore, it is important for organisations to manage their innovations effectively to ensure that their business grows and remains relevant. Managing innovation is not an easy task and requires that many different components of an organisation and its market should be in place and are managed well. Organisations should not take innovation lightly, but they should ensure that it is managed with care, just as they manage any other resource. Many times, organisations do not know where to start managing their ideas and innovations so that they can increase their competitive advantage. The research seeks to find all the different factors within the organisational and external domains that need to be taken into consideration when dealing with innovation. The different factors are used to develop a conceptual framework that describes the different concepts and their relationships with one another. The concepts are obtained from literature and then categorised and synthesised to form the conceptual framework. The conceptual framework does not aim to be an improvement of existing innovation models, but rather to give an understanding of the factors that need to be taken into consideration when organisations want to start the journey of managing their innovations. In order to validate the conceptual framework, an idea management tool is developed that assists with the implementation of an innovation strategy and framework at an organisation that wants a more defined and official innovation management process. The result of the research is a conceptual framework that can be used by organisations to assist with the development and implementation of an innovation strategy. It could also give a better understanding of the innovation management sphere and where to start, in order to implement it. The framework also highlights where idea management tools can be useful within the process to assist organisations with managing innovations effectively.AFRIKAANS OPSOMMING: Groot besighede verloor dikwels hul mededingende voordeel teenoor ander innoverende organisasies wat binne dieselfde mark as hulle funksioneer. Om in vandag se kompeterende mark te kan oorleef, is dit noodsaaklik vir organisasies om innoverend te wees. Dit is dus belangrik vir organisasies om innoverende idees op ‘n effektiewe manier te bestuur en sodoende te verseker dat hul besigheid groei en relevant bly. Dis nie ‘n maklike taak om innovasie te bestuur nie, en dit vereis dat sekere belangrike aspekte in plek moet wees vir innovasie om in die mark en besigheidsplek te kan floreer. Innovasie is nie ‘n kwessie wat besighede ligtelik moet opneem nie, maar dis iets wat bestuur moet word met dieselfde sorg wat enige ander hulpbronne bestuur sou word. Organisasies weet egter nie altyd waar of hoe om hul idees en innovasies te bestuur om hul mededingende voordeel te kan bevorder nie. Die navorsingstuk ondersoek verskeie faktore binne die besigheidsomgewing en eksterne omgewing wat in ag geneem moet word wanneer innovasie ter sprake is. Die verskillende faktore word later gebruik om ‘n konsepsuele raamwerk te skep om die verskillende konsepte asook hul verwantskappe met mekaar te verduidelik. Die konsepte word deur die beskikbare literatuur oor die onderwerp geidentifiseer en gekategoriseer om die raamwerk te skep. Die doel van die raamwerk is nie om bestaande innovasie modelle te verbeter nie, maar eerder om die verskillende faktore uiteen te sit wat oorweeg moet word wanneer ‘n organisasie beoog om hul innovasies beter te bestuur. ‘n Innovasie-bestuur sagteware stelsel is geskep om die validasie van die konsepsuele raamwerk meer prakties te kon doen. Die raamwerk en stelsel is getoets by ‘n organisasie wat die behoefte het om hul innovasie-bestuur proses te verbeter, en dit het die organisasie gehelp om die waarde van ‘n innovasie strategie en stelsel te kon raaksien. Die navorsing het bewys dat ‘n konsepsuele raamwerk organisasies kan help om ‘n innovasie-strategie te formuleer en te implementeer, asook om innovasie bestuur en die implementering daarvan beter te verduidelik. Die raamwerk lig ook uit hoe innovasie-bestuur hulpbronne organisasies kan help om hul innovasies beter en meer effektief te kan bestuur.Master

    Contributors

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    The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants.The Andrew W. Mellon Foundation and the National Library of Estonia organized a Conference on Union Catalogs which took place in Tallinn, in the National Library of Estonia on October 17–19, 2002. The Conference presented and discussed analytical papers dealing with various aspects of designing and implementing union catalogs and shared cataloging systems as revealed through the experiences of Eastern European, Baltic and South African research libraries. Here you can find the texts of the conference papers and the list of contributors and participants

    Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia.

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    Histone lysine methylation, mediated by mixed-lineage leukemia (MLL) proteins, is now known to be critical in the regulation of gene expression, genomic stability, cell cycle and nuclear architecture. Despite MLL proteins being postulated as essential for normal development, little is known about the specific functions of the different MLL lysine methyltransferases. Here we report heterozygous variants in the gene KMT2B (also known as MLL4) in 27 unrelated individuals with a complex progressive childhood-onset dystonia, often associated with a typical facial appearance and characteristic brain magnetic resonance imaging findings. Over time, the majority of affected individuals developed prominent cervical, cranial and laryngeal dystonia. Marked clinical benefit, including the restoration of independent ambulation in some cases, was observed following deep brain stimulation (DBS). These findings highlight a clinically recognizable and potentially treatable form of genetic dystonia, demonstrating the crucial role of KMT2B in the physiological control of voluntary movement.Funding for the project was provided by the Wellcome Trust for UK10K (WT091310) and DDD Study. The DDD study presents independent research commissioned by the Health Innovation Challenge Fund [grant number HICF-1009-003] - see www.ddduk.org/access.html for full acknowledgement. This work was supported in part by the Intramural Research Program of the National Human Genome Research Institute and the Common Fund, NIH Office of the Director. This work was supported in part by the German Ministry of Research and Education (grant nos. 01GS08160 and 01GS08167; German Mental Retardation Network) as part of the National Genome Research Network to A.R. and D.W. and by the Deutsche Forschungsgemeinschaft (AB393/2-2) to A.R. Brain expression data was provided by the UK Human Brain Expression Consortium (UKBEC), which comprises John A. Hardy, Mina Ryten, Michael Weale, Daniah Trabzuni, Adaikalavan Ramasamy, Colin Smith and Robert Walker, affiliated with UCL Institute of Neurology (J.H., M.R., D.T.), King’s College London (M.R., M.W., A.R.) and the University of Edinburgh (C.S., R.W.)

    Riding the Technology Wave

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    E resources : discovery opportunities from OCLC

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    Paper presented at the 2 day Seminar, 8-9 June 2011 "The e-Learning environment: future trends and impact on library services", Sanlam Auditorium, Conference Centre, Hatfield Campus, Pretoria, South Africa.SWET

    Anisotropy in strong ground motion in the 1994 Arthur's Pass earthquake

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    Directivity effects are assessed by examining strong ground motion records from the 1994 Arthur's Pass earthquake in light of evidence presented by past researchers. This thesis focusses primarily on intra site differences in anisotropic ground motion, achieved by analysing different components of ground motion. Problems are encountered in the selection of a fault plane. It is most likely that the fault plane assumed for analysis is not consistent with the actual fault plane. Despite these problems, some observations of anisotropic behaviour are made at the Arthur's Pass, Flock Hill and Lake Coleridge sites that are consistent with rupture on the assumed fault plane. The determination of directivity effects is based on analysis of fault normal and fault parallel components of acceleration, velocity and displacement records, in addition to Fourier and response spectra derived from the ground motion acceleration records. A further study is carried out on peak ground accelerations. Existing directivity research deals primarily with fault normal amplification in forward rupture directivity regions; that is, at sites located in the path of the moving rupture front. The results of a simple model application suggest that in some cases, fault parallel amplification may be significant next to fault planes. This is highlighted in far field Fourier amplitude predictions for the Arthur's Pass Police Station
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