Gel with Ectoine improves wound healing on a thermal burn model in rats

Due to the ability to create complexes of water molecules on the surface of the mucous membrane, ectoine is a promising compound for the treatment of burns. Evaluate the reparative activity of Ectoine using the thermal burn model in rats. In male rats (n=30), 2 thermal burns were counteracted under counter-anesthesia, one of which was treated by topical application of the test drugs for 7 days, and the other served as a contro

Effects of bischofite gel on reparative processes in wound healing

The study showed that the best results were obtained with external use of the gel with bischofite. Actovegin has a less significant but pronounced reparative effect on this model. The least satisfactory results were obtained when applying Contractube

RATAN-600 7.6-cm Deep Sky Strip Surveys at the Declination of the SS433 Source During the 1980-1999 Period. Data Reduction and the Catalog of Radio Sources in the Right-Ascension Interval 7h < R.A. < 17h

We use two independent methods to reduce the data of the surveys made with RATAN-600 radio telescope at 7.6 cm in 1988-1999 at the declination of the SS433 source. We also reprocess the data of the "Cold" survey (1980-1981). The resulting RCR (RATAN COLD REFINED) catalog contains the right ascensions and fluxes of objects identified with those of the NVSS catalog in the right-ascension interval 7h < R.A. < 17h. We obtain the spectra of the radio sources and determine their spectral indices at 3.94 and 0.5 GHz. The spectra are based on the data from all known catalogs available from the CATS, Vizier, and NED databases, and the flux estimates inferred from the maps of the VLSS and GB6 surveys. For 245 of the 550 objects of the RCR catalog the fluxes are known at two frequencies only: 3.94 GHz (RCR) and 1.4 GHz (NVSS). These are mostly sources with fluxes smaller than 30 mJy. About 65% of these sources have flat or inverse spectra (alpha > -0.5). We analyze the reliability of the results obtained for the entire list of objects and construct the histograms of the spectral indices and fluxes of the sources. Our main conclusion is that all 10-15 mJy objects found in the considered right-ascension interval were already included in the decimeter-wave catalogs.Comment: 26 pages, 18 figure

Study of the Power Beam Pattern of RATAN-600 During the Deep RZF Survey (1998-2003)

This paper proposes a method for constructing an experimental power beam pattern (PB) of RATAN-600 based on the sample of NVSS sources observed in the process of a deep sky survey near local zenith. The data obtained from observations of radio sources at wave 7.6 cm in nine bands of the survey (the 2002 and 2003 sets) are used to construct vertical PB of the telescope at rather large offsets from the central horizontal section of the PB (+/-36'). The experimental PBs obtained using different methods are compared and the root-mean-square deviations of the experimental PB from the corresponding computed PB are determined. The stability of the power beam pattern in its central part (+/-6') during the RATAN-600 Zenith Field (RZF) survey (1998-2003) and the accuracies of the fluxes of the sources observed within the framework of this survey and included into the RZF catalog are estimated.Comment: 15 pages, 17 figure

Investigação do efeito reparador do gel de ectoína em modelo de queima térmica

Due to the ability to create complexes of water molecules on the surface of the mucous membrane, ectoine is a promising compound for the treatment of burns. In male rats (n=30), 2 thermal burns were counteracted under counter-anesthesia, one of which was treated by topical application of the test drugs for 7 days, and the other served as a control. On the 8th day, skin samples in the area of the burn were taken for morphological examination. Histological sections were then scored by independent experts. The best histological picture of thermally damaged tissues was demonstrated by animals receiving ectoine. A less significant, but pronounced reparative effect was observed in histological samples of the actovegin group. The least significant reparative effect was demonstrated by contractubex. Ectoine improved the histological picture, improved repair and reduced the inflammatory response of the tissues and can be recommended for further preclinical studies as a treatment for burns.Debido a la capacidad de crear complejos de moléculas de agua en la superficie de la membrana mucosa, la ectoina es un compuesto prometedor para el tratamiento de las quemaduras. En ratas macho (n = 30), 2 quemaduras térmicas se contrarrestaron con contraestesia, una de las cuales se trató mediante la aplicación tópica de los fármacos de prueba durante 7 días, y la otra sirvió como control. En el octavo día, se tomaron muestras de piel en el área de la quemadura para un examen morfológico. Las secciones histológicas fueron calificadas por expertos independientes. El mejor cuadro histológico de los tejidos dañados térmicamente fue demostrado por los animales que recibieron ectoína. Se observó un efecto reparador menos significativo, pero pronunciado en muestras histológicas del grupo actovegin. El efecto reparador menos significativo fue demostrado por contractubex. Ectoine mejoró el cuadro histológico, mejoró la reparación y redujo la respuesta inflamatoria de los tejidos y puede recomendarse para estudios preclínicos adicionales como tratamiento para las quemaduras.Devido à capacidade de criar complexos de moléculas de água na superfície da membrana mucosa, a ectoína é um composto promissor para o tratamento de queimaduras. Em ratos machos (n = 30), duas queimaduras térmicas foram combatidas sob anestesia, uma das quais foi tratada por aplicação tópica das drogas de teste por 7 dias, e a outra serviu como controle. No oitavo dia, amostras de pele na área da queimadura foram retiradas para exame morfológico. As secções histológicas foram então classificadas por especialistas independentes. O melhor quadro histológico dos tecidos termicamente lesados foi demonstrado pelos animais que receberam ectoína. Um efeito reparador menos significativo, mas pronunciado, foi observado em amostras histológicas do grupo da actovegina. O efeito reparador menos significativo foi demonstrado pelo contratoubex. Ectoine melhorou o quadro histológico, melhorou o reparo e reduziu a resposta inflamatória dos tecidos e pode ser recomendado para estudos pré-clínicos adicionais como tratamento para queimaduras

Catalog of Radio Galaxies with z>0.3. I:Construction of the Sample

The procedure of the construction of a sample of distant ($z>0.3$) radio galaxies using NED, SDSS, and CATS databases for further application in statistical tests is described. The sample is assumed to be cleaned from objects with quasar properties. Primary statistical analysis of the list is performed and the regression dependence of the spectral index on redshift is found.Comment: 9 pages, 6 figures, 2 table

Correlation properties of the maps of the NVSS survey and WMAP ILC

In this paper we study one-dimensional sections of the maps of WMAP ILC and of the NVSS survey on scale lengths of 0.75, 3, 4.5, and 6.75 degrees and analyze the correlation properties of the sections. On these maps we identify the domains where the absolute value of the correlation coefficient exceeds 0.5. The catalog of such domains is presented. It is shown that the number of the domains agrees with the number of such domains on simulated maps and this fact may be indicative of just statistical agreement of the arrangement of the domains considered.Comment: 8 pages, 2 figure

ЛАБОРАТОРНАЯ ДИАГНОСТИКА ОСТРЫХ РЕСПИРАТОРНЫХ ВИРУСНЫХ ИНФЕКЦИЙ В УСЛОВИЯХ ЭВОЛЮЦИОННОЙ ИЗМЕНЧИВОСТИ ВИРУСОВ ГРИППА

As a result of laboratory investigation 1651 patients at the age from 0 months till 18 years, hospitalized with ARI from 2008 to 2011, in ¾ cases the virus etiology of disease was found. At the same time in 2009-2011 was marked significant prevalence of pandemic influenza virus infection A(Н1N1)v in a kind mono- and mikst-infections (in 18,8 and 10,2 % of cases accordingly), and adenoviruses, espiratory sincitial viruses and parainfluenza were the most frequent concomitants (in 4,8, 3,2 and 2,4 % of cases). In a clinical picture of disease acute nasopharynx lesion (67,8 %) was predominated, complicating by croup in 12,2 % of cases, by acute bronchitis in 12,1 % of cases, and more rare by pneumonia (in 8,2 % of cases). The analysis of results of immunofluorescence test in comparison with the cumulative data of other laboratory methods (polymerase chain reaction, immuneenzyme analysis, virus isolation, serological examination) has shown possibility of discovery with its help the valuable information on etiology ARI, including influenza, at early stages of disease and in short terms.В результате лабораторного обследования 1651 пациента в возрасте от 0 мес. до 18 лет, госпитализированных с ОРВИ-инфекцией в период с 2008 по 2011 г., в 67,2–77,8% случаев выявлена вирусная этиология заболевания. При этом в 2009–2011 гг. отмечалось преобладание пандемического вируса гриппа А(Н1N1)v в виде моно- и микст-инфекций (в 18,8 и 10,2% случаев соответственно), а наиболее частыми ассоциантами были аденовирусы, РС-вирусы и вирусы парагриппа (в 4,8, 3,2 и 2,4% случаев). В клинической картине заболевания преобладал острый ринофарингит (67,8%), осложняющийся в 12,2% случаев острым стенозирующим ларинготрахеитом, в 12,1% случаев – острым бронхитом, реже – пневмонией (в 8,2% случаев). Анализ результатов иммунофлуоресцентного метода в сравнении с совокупными данными других лабораторных тестов (полимеразная цепная реакция, иммуноферментный анализ, вирусовыделение, серология) показал возможность получения с его помощью ценной информации об этиологии ОРВИ, включая грипп, на ранних стадиях заболевания и в короткие сроки