Die Wirkung von MOOCs und iMooX.at aus Sicht von Kursersteller:innen

iMooX.at wird im Rahmen des Projekts „MooX – Die MOOC-Plattform als Service für alle österreichischen Universitäten“ (2020–2023) als nationale Plattform für Hochschulen ausgebaut. Im Beitrag werden bisherige Ergebnisse und Wirkungen des Projekts dargestellt. So wurden bereits 70 MOOCs durchgeführt (geplant waren 33). In problemzentrierten Interviews mit fünf Kursersteller:innen wurden zudem Wirkungen von MOOCs und iMooX.at als Plattform gesammelt. Kursersteller:innen bestätigen in einer Online-Befragung (n=17) im hohen Maße, dass iMooX.at zur Verbreitung von OER beiträgt und positive Wirkungen für unterschiedliche Gruppen hat. Dieses Projekt wurde am 1. Juni 2023 im Rahmen einer Online-Veranstaltung des BMBWF präsentiert. Die Präsentationsunterlagen finden Sie hier

Advocating for implementation of the Global Action Plan on Physical Activity: challenges and support requirements

Background: There is limited understanding of the challenges experienced and supports required to aid effective advocacy of the Global Action Plan on Physical Activity (GAPPA). The purpose of this study was to assess the challenges experienced and supports needed to advocate for the GAPPA across countries of different income levels. Methods: Stakeholders working in an area related to the promotion of physical activity were invited to complete an online survey. The survey assessed current awareness and engagement with the GAPPA, factors related to advocacy, and the perceived challenges and supports related to advocacy for implementation of the GAPPA. Closed questions were analyzed in SPSS, with a Pearson’s chi-square test used to assess differences between country income level. Open questions were analyzed using inductive thematic analysis. Results: Participants (n = 518) from 81 countries completed the survey. Significant differences were observed between country income level for awareness of the GAPPA and perceived country engagement with the GAPPA. Challenges related to advocacy included a lack of support and engagement, resources, priority, awareness, advocacy education and training, accessibility, and local application. Supports needed for future advocacy included guidance and support, cooperation and alliance, advocacy education and training, and advocacy resources. Conclusions: Although stakeholders from different country income levels experience similar advocacy challenges and required supports, how countries experience these can be distinct. This research has highlighted some specific ways in which those involved in the promotion of physical activity can be supported to scale up advocacy for the GAPPA. When implementing such supports, consideration of regional, geographic, and cultural barriers and opportunities is important to ensure they are effective and equitable

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when performing flow cytometry experiments and includes comprehensive sections describing phenotypes and functional assays of all major human and murine immune cell subsets. Notably, the Guidelines contain helpful tables highlighting phenotypes and key differences between human and murine cells. Another useful feature of this edition is the flow cytometry analysis of clinical samples with examples of flow cytometry applications in the context of autoimmune diseases, cancers as well as acute and chronic infectious diseases. Furthermore, there are sections detailing tips, tricks and pitfalls to avoid. All sections are written and peer‐reviewed by leading flow cytometry experts and immunologists, making this edition an essential and state‐of‐the‐art handbook for basic and clinical researchers.DFG, 389687267, Kompartimentalisierung, Aufrechterhaltung und Reaktivierung humaner Gedächtnis-T-Lymphozyten aus Knochenmark und peripherem BlutDFG, 80750187, SFB 841: Leberentzündungen: Infektion, Immunregulation und KonsequenzenEC/H2020/800924/EU/International Cancer Research Fellowships - 2/iCARE-2DFG, 252623821, Die Rolle von follikulären T-Helferzellen in T-Helferzell-Differenzierung, Funktion und PlastizitätDFG, 390873048, EXC 2151: ImmunoSensation2 - the immune sensory syste

Performance validation of the ATLAS muon spectrometer

Das Prinzip der Impulsmessung im ATLAS Muonspektrometer basiert auf der Rekonstruktion von Myonspuren in einem Magnetfeld von durchschnittlich 0.5T mithilfe von Präzisionsdriftrohren mit einer mittleren Ortsauflösung von weniger als 80 Mikrometer. Um eine Impulsauflösung von 10% für Myonen mit einem Transversalimpuls von annähernd 1 TeV zu erreichen, muss die Position der Detektoren über ein Messvolumen von annähernd 16000 m3 auf Mikrometer genau bekannt sein.Ein optisches Vermessungssystem, bestehend aus raffiniert verteilten Lichtquellen-Kamera-Paaren überwacht kontinuierlich Bewegung und Verformung der Driftkammern.Ein Teil des ATLAS Myonspektrometers wurde am CERN entlang eines Myonenstrahls in Originalgröße aufgebaut. Der Aufbau umfasst sowohl Präzisionskammern als auch Triggerkammern. Alle Kammern sind vollständig mit ihren optischen Vermessungsgeräten ausgestattet. Die gewählte Anordnung der Detektorkammern entlang des Teststrahls ermöglicht eine erste Erprobung des gesamten Systems. Ein wichtiger Bestandteil dieses Systemtests sind die Überprüfung des Spurrekonstruktionsalgorithmus an echten Detektordaten, sowie die Validierung der geforderten Präzision des optischen Vermessungssystems. Die Ergebnisse dieser Tests werden hier präsentiert.The ATLAS Muon Spectrometer aims at a momentum resolution better than 10% for transverse momentum values ranging from 6 GeV to 1 TeV.Precision tracking will be performed by Ar-CO2 filled Monitored Drift Tube chambers (MDTs) with a single wire resolution of less than 100 micrometer. In total, about 1200 chambers, arranged in a large structure, will allow muon track measurements over distances up to 15 m in a magnetic field of about 0.5 T. Given the large size of the spectrometer, it is impossible to keep the shape of the muon chambers and their positions stable within the requested accuracy of 50 micrometer. Therefore the concept of an optical alignment system was chosen. An alignment accuracy of 30 to 40 micrometer must be achieved to meet the design resolution.This work is dedicated to the validation of the required precision of the optical alignment system with straight muon tracks in a test beam environment. The outcome of the first test on the track fit performance of the ATLAS reconstruction software with real detector data is presented, followed by detailed studies of MDT chamber performance in the test beam, involving analysis of data taken at different beam energies and with different amount of material placed along the beam. A detailed comparison of chamber position obtained by tracking and obtained by the optical alignment system allows the validation of the general performance of the alignment system of the ATLAS muon spectrometer.10

Performance Validation of the ATLAS Muon Spectrometer

ATLAS (A Toroidal LHC ApparatuS) is a general-purpose experiment for the future Large Hadron Collider (LHC) at CERN, which is scheduled to begin operation in the year 2007, providing experiments with proton-proton collisions. The center-of-mass energy of 14TeV and the design luminosity of 1034 cm−2s−1 will allow to explore many new aspects of fundamental physics. The ATLAS Muon Spectrometer aims at a momentum resolution better than 10% for transverse momentum values ranging from pT = 6 GeV to pT = 1TeV. Precision tracking will be performed by Ar-CO2-gas filled Monitored Drift Tube chambers (MDTs), with a single wire resolution of < 100 μm. In total, about 1 200 chambers, arranged in a large structure, will allow muon track measurements over distances up to 15m in a magnetic field of 0.5 T. Given the large size of the spectrometer it is impossible to keep the shape of the muon chambers and their positions stable within the requested tracking accuracy of 50 μm. Therefore the concept of an optical alignment system was chosen. An alignment accuracy of 30–40 μm must be achieved in order to meet the design resolution. This work is dedicated to the validation of the required precision of the optical alignment system with straight muon tracks in a test beam environment. A 1:1 test stand of the ATLAS muon spectrometer has been setup in the CERN north area on the H8 beam line. The setup consists of two stands, including both tracking and trigger chambers, which emulate in detail projective towers of the barrel and of the end-cap spectrometers, allowing an overall system test. An important aspect of the system test is the study of the offline reconstruction software, and the development of the code necessary for the application of the ATLAS software framework to real detector data. A C++ package, developed to fulfill this task, is described. The outcome of the first test on the track fit performance of the ATLAS reconstruction software with real detector data is presented, followed by detailed studies of MDT chamber performance in the test beam, involving analysis of data taken at different beam energies and with different amount of material placed along the beam. A detailed comparison of chamber position obtained by tracking and obtained by the optical alignment system allows the validation of the general performance of the alignment system of the ATLAS muon spectrometer. Additionally, the concept of a final test on the overall performance of MDT chambers, coupled with RPC chambers, before their final installation in ATLAS is demonstrated on a cosmic ray test stand

Thermal bath Altprags

Abweichender Titel laut Übersetzung der Verfasserin/des VerfassersZsfassung in engl. SpracheInhalt dieser Diplomarbeit ist die Auseinandersetzung mit der Badekultur im alpinen Raum und der Versuch einer zeitgemäßen architektonischen Interpretation dieser Tradition im Sinne eines sanften Tourismus. Fokus und Ausgangspunkt der Recherchen ist die lange Badegeschichte in Südtirol, das ein reiches Vorkommen an Quellen mit mineralhaltigen Gewässern hat. Gebadet wurde vor allem in sogenannten Bauernbädern, von denen einige im Laufe der Zeit aufgrund ihrer großen Beliebtheit zu prächtigen Kur- und Sommerfrischeorten ausgebaut wurden. So entstand ein eigenes gesellschaftlich-kulturelles Phänomen, das einen wichtigen Meilenstein darstellt in der Entwicklung des Fremdenverkehrs in dieser Region. Seine Blütezeit erlebte es um die Jahrhundertwende, auf die in der ersten Hälfte des 20. Jahrhunderts ein langsamer Verfall folgte. Erst im Zuge des wachsenden Interesses nach Erholung und Entspannung in alpiner Landschaft wurden in den letzten Jahrzehnten vermehrt Themen und Elemente aus diesem Brauchtum aufgegriffen. Sie bilden die Grundlage für das Konzept und den Entwurf eines Kurhauses, das an den Mineralquellen des ehemaligen und verlassenen Bades Altprags in den Pragser Dolomiten in Südtirol verortet ist.The content of this thesis is the examination of bathing culture in the alpine region of South Tyrol and the attempt to design a contemporary architectural interpretation of this tradition following the idea of a sustainable tourism. Focus and origin of the research is the long history of bathing culture in South Tyrol, which is rich of sources of mineral springs. People mainly took their baths in bathhouses, which were usually part of farmsteads located close to the springs. Based on their popularity some of them enlarged to stately health resorts. It originated a particular social-cultural phenomenon, which describes an important milestone in the development of tourism in this region. It had it`s florescence around the turn of the century, before a slow decadence followed in the first half of the 20th century. In the course of increasing interests in recreation and relaxation in alpine landscape subjects and elements of this tradition were emerged in the last decades. They build the basis of the concept and design of a health resort house, which is located close to the mineral springs of the former and abandoned bath of Altprags in the dolomites of South Tyrol.9

Conditioning of MWPCs for the LHCb Muon System

We report on the conditioning of the Multi-Wire Proportional Chambers (MWPC) for the LHCb muon system. The MWPCs destined for the inner regions of the muon stations have demanding requirements in terms of rate capability (&gt;100kHz/cm$^2$) and ageing properties. Conditioning of the chambers is therefore of utmost importance. After construction, all chambers undergo a conditioning procedure in two steps, resulting in successful cleaning of anode and cathode surfaces. Conditioned chambers show excellent behaviour under working conditions

Elucidating the Role of Honey Bees as Biomonitors in Environmental Health Research

Recently, the One Health concept, which recognizes the interconnectedness of environmental, animal, and human health, has gained popularity. To collect data on environmental pollutants potentially harmful to human health over time, researchers often turn to natural organisms known as biomonitors. Honey bees, in particular, prove to be exceptionally valuable biomonitors due to their capacity to accumulate pollutants from the air, soil, and water within a specific radius during their foraging trips. This systematic literature review summarizes the previous application of the bee species Apis mellifera in pollutant monitoring in articles published during the period of 2010–2020. Nineteen studies were included in this systematic literature review. Of these studies, the majority (n = 15) focused on the detection of heavy metals in honey bees and beehive products, while 4 studies focused on air pollution by polycyclic aromatic hydrocarbons or particulate matter. The matrix most often applied was the whole honey bee. The included studies demonstrated that honey bees and hive products deliver quantitative and qualitative information about specific pollutants. In this regard, the whole honey bee was found to be the most reliable biomonitor. We found that the included studies differed in design and the methods used. Standardized studies could foster a more consistent interpretation of the levels detected in beehive matrices from an environmental health perspective