Caracterización de la estructura fina de las fibras de poliamida 6 mediante la técnica de solubilidad diferencial

Se describe la puesta a punto de la técnica de solubilidad diferencial en mezclas fenol/isopropanol como parámetro de la estructura fina de las fibras de poliamida 6.Este parámetro ha permitido detectar diferencias entre sustratos de poliamida 6 del mismo tipo producidos por diferentes compañías. También se han apreciado diferencias de solubilidad diferencial en sustratos de poliamida 6 fabricados con diferentes relaciones de estirado. Los diferentes sustratos se han caracterizado tambiénprocediendo a medidas de cristalinidad (densidad) y orientación(módulo sónico)

Evolutionary undersampling for extremely imbalanced big data classification under apache spark

The classification of datasets with a skewed class distribution is an important problem in data mining. Evolutionary undersampling of the majority class has proved to be a successful approach to tackle this issue. Such a challenging task may become even more difficult when the number of the majority class examples is very big. In this scenario, the use of the evolutionary model becomes unpractical due to the memory and time constrictions. Divide-and-conquer approaches based on the MapReduce paradigm have already been proposed to handle this type of problems by dividing data into multiple subsets. However, in extremely imbalanced cases, these models may suffer from a lack of density from the minority class in the subsets considered. Aiming at addressing this problem, in this contribution we provide a new big data scheme based on the new emerging technology Apache Spark to tackle highly imbalanced datasets. We take advantage of its in-memory operations to diminish the effect of the small sample size. The key point of this proposal lies in the independent management of majority and minority class examples, allowing us to keep a higher number of minority class examples in each subset. In our experiments, we analyze the proposed model with several data sets with up to 17 million instances. The results show the goodness of this evolutionary undersampling model for extremely imbalanced big data classification

El ensayo de solubilidad diferencial como método de caracterización de la estructura fina de las fibras químicas

La solubilidad diferencial es un ensayo físico-químico para la caracterización de la estructura fina de las fibras de poliéster, poliamida, acrílicas y fibras químicas de celulosa. En esta publicación se describe esta técnica, así como la influencia de las variables del ensayo. También se interpreta la curva de solubilidad diferencial vs. temperatura del ensayo. Por último, se citan ejemplos de campos de aplicación de este ensayo a diferentes grupos de sustratos de las mencionadas fibras

Onomatopoeia, gestures, actions and words: How do caregivers use multimodal cues to communicate with their children

Most research on how children learn the mapping between words and world has assumed that language is arbitrary, and has investigated language learning in contexts in which objects referred to are present in the environment. Here, we report analyses of a semi-naturalistic corpus of caregivers talking to their 2-3 year-old. We focus on caregivers’ use of non-arbitrary cues across different expressive channels: both iconic (onomatopoeia and representational gestures) and indexical (points and actions with objects). We ask if these cues are used differently when talking about objects known or unknown to the child, and when the referred objects are present or absent. We hypothesize that caregivers would use these cues more often with objects novel to the child. Moreover, they would use the iconic cues especially when objects are absent because iconic cues bring to the mind’s eye properties of referents. We find that cue distribution differs: all cues except points are more common for unknown objects indicating their potential role in learning; onomatopoeia and representational gestures are more common for displaced contexts whereas indexical cues are more common when objects are present. Thus, caregivers provide multimodal non-arbitrary cues to support children’s vocabulary learning and iconicity – specifically – can support linking mental representations for objects and labels

Étude de l'interaction de la polyamide 6 avec l'iode à l'aide d'une spectrométrie FT-IR

Se estudian los espectros IR de varias muestras de poliamida 6 tratadas con soluciones de yodo y yoduro potásico de diferentes concentraciones, y los de sus respectivas desorciones de yodo por tratamiento con tiosulfato sódico. Los cambios espectrales observados se han relacionado con las variaciones en las formas polimórficas cristalinas y de la poliamida, que ponen de manifiesto la formación de un complejo entre el ión tri-yoduro y el polímero durante el proceso de sorción de yodo y un cambio de estructura durante la desorción.The IR spectra of several samples of polyamide 6 treated with iodine and potassium iodide solutions of different concentrations were studied, along with their respective desorption of iodine under treatment with sodium thiosulphate. The spectral changes observed were related to variations in the and polymorphic crystalline shapes of the polyamide, which reveal the formation of a complex between the triiodide ion and the polymer during the process of iodine sorption and a change in structure during desorption.L’étude porte sur les spectres IR de plusieurs échantillons de polyamide 6, traités avec des solutions d’iode et d’iodure de potassium à différentes concentrations, et sur les spectres de leurs respectives désorptions d’iode après un traitement au thiosulfate de sodium. Les changements spectraux observés ont été associés aux variations dans les formes polymorphiques cristallines et de la polyamide, qui mettent en évidence la formation d’un complexe entre l’ion tri-iodure et le polymère pendant le processus de sorption de l’iode et un changement de structure pendant la désorption

Onomatopoeia, gestures, actions and words: how do caregivers use multimodal cues in their communication to children?

Most research on how children learn the mapping between words and world has assumed that language is arbitrary, and has investigated language learning in contexts in which objects referred to are present in the environment. Here, we report analyses of a semi-naturalistic corpus of caregivers talking to their 2-3 year-old. We focus on caregivers’ use of non-arbitrary cues across different expressive channels: both iconic (onomatopoeia and representational gestures) and indexical (points and actions with objects). We ask if these cues are used differently when talking about objects known or unknown to the child, and when the referred objects are present or absent. We hypothesize that caregivers would use these cues more often with objects novel to the child. Moreover, they would use the iconic cues especially when objects are absent because iconic cues bring to the mind’s eye properties of referents. We find that cue distribution differs: all cues except points are more common for unknown objects indicating their potential role in learning; onomatopoeia and representational gestures are more common for displaced contexts whereas indexical cues are more common when objects are present. Thus, caregivers provide multimodal non-arbitrary cues to support children’s vocabulary learning and iconicity – specifically – can support linking mental representations for objects and labels

Chagas disease in Latin American migrants: a Spanish challenge

AbstractChagas’ disease affects millions in Latin America and is the leading cause of cardiomyopathy and death due to cardiovascular disease in patients aged 30–50 years. As a consequence of immigration it has settled in several European countries, where besides imported cases, autochthonous infections arise through vertical transmission and blood/organ donation. All Latin American immigrants who attended our Unit were screened for T. cruzi infection (ELISA and IFAT ± PCR). An ECG and echocardiogram were requested for all positive patients, and oesophageal manometry, barium swallow and barium enema were requested according to patient symptoms. All patients under 50 years without severe cardiac involvement and who had not received correct treatment previously were treated with benznidazole 5 mg/kg/day for 60 days. Patients were followed-up with serology and PCR 1 month after treatment ended and every 6 months thereafter. A total of 1146 Latin Americans were screened for T. cruzi (357 positive serology results). The typical patient profile was a Bolivian female, of rural origin, in her fourth decade of life, without evidence of visceral involvement. Treatment tolerance was poor, with 29.7% discontinuing treatment due to adverse reactions. Among those with adverse reactions (52%), the most frequent were cutaneous hypersensitivity (68.7%), gastrointestinal upset (20%) and nervous system disturbances (16.2%). T. cruzi infection is no longer limited to Latin America. Poor treatment tolerance can limit current treatment options. More epidemiological data are necessary to estimate the magnitude of a problem of great relevance for public health and health resource planning

Maternal metabolic stress may affect oviduct gatekeeper function

We hypothesized that elevated non-esterified fatty acids (NEFA) modify in vitro bovine oviduct epithelial cell (BOEC) metabolism and barrier function. Hereto, BOECs were studied in a polarized system with 24h-treatments at day 9: 1) CONTROL (0µM NEFA + 0%EtOH), 2) SOLVENT CONTROL (0µM NEFA + 0.45%EtOH), 3) BASAL NEFA (720µM NEFA + 0.45%EtOH in the basal compartment), 4) APICAL NEFA (720µM NEFA + 0.45%EtOH in the apical compartment). FITC-albumin was used for monolayer permeability assessment, and related to Transepithelial Electric Resistance (TER). Fatty acid (FA), glucose, lactate and pyruvate concentrations were measured in spent medium. Intracellular lipid droplets (LD) and FA-uptake were studied using Bodipy 493/503 and immunolabelling of FA-transporters (FAT/CD36, FABP3 and caveolin1). BOEC-mRNA was retrieved for qRT-PCR. Results revealed that APICAL NEFA reduced relative TER-increase (46.85%) during treatment, and increased FITC-albumin flux (27.59%) compared to other treatments. In BASAL NEFA, FAs were transferred to the apical compartment as free FAs: mostly palmitic and oleic acid increased, respectively 56.0 % and 33.5% of initial FA-concentrations. APICAL NEFA allowed no FA-transfer, but induced LD-accumulation and upregulated FA-transporter expression (↑CD36, ↑FABP3, ↑CAV1-protein-expression). Gene expression in APICAL NEFA indicated increased anti-apoptotic (↑BCL2) and anti-oxidative (↑SOD1) capacity, upregulated lipid metabolism (↑CPT1, ↑ACSL1 and ↓ACACA), and FA-uptake (↑CAV1). All treatments had similar carbohydrate metabolism and oviduct function specific gene expression (=OVGP1, ESR1, FOXJ1). Overall, elevated NEFAs affected BOEC-metabolism and barrier function differently depending on NEFA-exposure side. Data substantiate the concept of the oviduct as a gatekeeper that may actively alter early embryonic developmental conditions