Material Properties Measurements for Selected Materials

Hugoniot equation of state measurements were made on Coconino sandstone, Vacaville basalt, Kaibab limestone, Mono Crater, pumice and Zelux (a polycarbonate resin) for pressures to 2 Mb. A single data point was obtained for fused quartz at 1.6 Mb. In addition to the hugoniot studies, the uniaxial compressive stress behavior of Vacaville basalt and Zelux was investigated at strain rates from about 10(exp -5)/sec to 10(exp 3)/second. The data presented include the stress - strain relations as a function of strain rate for these two materials

Statistics of selectively neutral genetic variation

Random models of evolution are instrumental in extracting rates of microscopic evolutionary mechanisms from empirical observations on genetic variation in genome sequences. In this context it is necessary to know the statistical properties of empirical observables (such as the local homozygosity for instance). Previous work relies on numerical results or assumes Gaussian approximations for the corresponding distributions. In this paper we give an analytical derivation of the statistical properties of the local homozygosity and other empirical observables assuming selective neutrality. We find that such distributions can be very non-Gaussian.Comment: 4 pages, 4 figure

Intersecting D-Branes on Shift Z2 x Z2 Orientifolds

We investigate Z2 x Z2 orientifolds with group actions involving shifts. A complete classification of possible geometries is presented where also previous work by other authors is included in a unified framework from an intersecting D-brane perspective. In particular, we show that the additional shifts not only determine the topology of the orbifold but also independently the presence of orientifold planes. In the second part, we work out in detail a basis of homological three cycles on shift Z2 x Z2 orientifolds and construct all possible fractional D-branes including rigid ones. A Pati-Salam type model with no open-string moduli in the visible sector is presented.Comment: 36 pages, 4 figures, refs. adde

Quantitative electron phase imaging with high sensitivity and an unlimited field of view

As it passes through a sample, an electron beam scatters, producing an exit wavefront rich in information. A range of material properties, from electric and magnetic field strengths to specimen thickness, strain maps and mean inner potentials, can be extrapolated from its phase and mapped at the nanoscale. Unfortunately, the phase signal is not straightforward to obtain. It is most commonly measured using off-axis electron holography, but this is experimentally challenging, places constraints on the sample and has a limited field of view. Here we report an alternative method that avoids these limitations and is easily implemented on an unmodified transmission electron microscope (TEM) operating in the familiar selected area diffraction mode. We use ptychography, an imaging technique popular amongst the X-ray microscopy community; recent advances in reconstruction algorithms now reveal its potential as a tool for highly sensitive, quantitative electron phase imaging

Coisotropic D8-branes and Model-building

Up to now chiral type IIA vacua have been mostly based on intersecting D6-branes wrapping special Lagrangian 3-cycles on a CY three-fold. We argue that there are additional BPS D-branes which have so far been neglected, and which seem to have interesting model-building features. They are coisotropic D8-branes, in the sense of Kapustin and Orlov. The D8-branes wrap 5-dimensional submanifolds of the CY which are trivial in homology, but contain a worldvolume flux that induces D6-brane charge on them. This induced D6-brane charge not only renders the D8-brane BPS, but also creates D=4 chirality when two D8-branes intersect. We discuss in detail the case of a type IIA Z2 x Z2 orientifold, where we provide explicit examples of coisotropic D8-branes. We study the chiral spectrum, SUSY conditions, and effective field theory of different systems of D8-branes in this orientifold, and show how the magnetic fluxes generate a superpotential for untwisted Kahler moduli. Finally, using both D6-branes and coisotropic D8-branes we construct new examples of MSSM-like type IIA vacua.Comment: 63 pages, 11 figures. Typos corrected and comments adde

Evolution of an Agriculture-Associated Disease Causing Campylobacter coli Clade: Evidence from National Surveillance Data in Scotland

The common zoonotic pathogen Campylobacter coli is an important cause of bacterial gastroenteritis worldwide but its evolution is incompletely understood. Using multilocus sequence type (MLST) data of 7 housekeeping genes from a national survey of Campylobacter in Scotland (2005/6), and a combined population genetic-phylogenetics approach, we investigated the evolutionary history of C. coli. Genealogical reconstruction of isolates from clinical infection, farm animals and the environment, revealed a three-clade genetic structure. The majority of farm animal, and all disease causing genotypes belonged to a single clade (clade 1) which had comparatively low synonymous sequence diversity, little deep branching genetic structure, and a higher number of shared alleles providing evidence of recent clonal decent. Calibration of the rate of molecular evolution, based on within-species genetic variation, estimated a more rapid rate of evolution than in traditional estimates. This placed the divergence of the clades at less than 2500 years ago, consistent with the introduction of an agricultural niche having had an effect upon the evolution of the C. coli clades. Attribution of clinical isolate genotypes to source, using an asymmetric island model, confirmed that strains from chicken and ruminants, and not pigs or turkeys, are the principal source of human C. coli infection. Taken together these analyses are consistent with an evolutionary scenario describing the emergence of agriculture-associated C. coli lineage that is an important human pathogen

D-brane Spectrum and K-theory Constraints of D=4, N=1 Orientifolds

We study the spectrum of stable BPS and non-BPS D-branes in Z_2 x Z_2 orientifolds for all choices of discrete torsion between the orbifold and orientifold generators. We compute the torsion K-theory charges in these D=4, N=1 orientifold models directly from worldsheet conformal field theory, and compare with the K-theory constraints obtained indirectly using D-brane probes. The K-theory torsion charges derived here provide non-trivial constraints on string model building. We also discuss regions of stability for non-BPS D-branes in these examples.Comment: 40 pages, 5 table

D-brane Deconstructions in IIB Orientifolds

With model building applications in mind, we collect and develop basic techniques to analyze the landscape of D7-branes in type IIB compact Calabi-Yau orientifolds, in three different pictures: F-theory, the D7 worldvolume theory and D9-anti-D9 tachyon condensation. A significant complication is that consistent D7-branes in the presence of O7^- planes are generically singular, with singularities locally modeled by the Whitney Umbrella. This invalidates the standard formulae for charges, moduli space and flux lattice dimensions. We infer the correct formulae by comparison to F-theory and derive them independently and more generally from the tachyon picture, and relate these numbers to the closed string massless spectrum of the orientifold compactification in an interesting way. We furthermore give concrete recipes to explicitly and systematically construct nontrivial D-brane worldvolume flux vacua in arbitrary Calabi-Yau orientifolds, illustrate how to read off D-brane flux content, enhanced gauge groups and charged matter spectra from tachyon matrices, and demonstrate how brane recombination in general leads to flux creation, as required by charge conservation and by equivalence of geometric and gauge theory moduli spaces.Comment: 49 pages, v2: two references adde

Observational Signatures and Non-Gaussianities of General Single Field Inflation

We perform a general study of primordial scalar non-Gaussianities in single field inflationary models in Einstein gravity. We consider models where the inflaton Lagrangian is an arbitrary function of the scalar field and its first derivative, and the sound speed is arbitrary. We find that under reasonable assumptions, the non-Gaussianity is completely determined by 5 parameters. In special limits of the parameter space, one finds distinctive ``shapes'' of the non-Gaussianity. In models with a small sound speed, several of these shapes would become potentially observable in the near future. Different limits of our formulae recover various previously known results.Comment: 53 pages, 5 figures; v3, minor revision, JCAP version; v4, numerical coefficients corrected in Appendix B, discussion on consistency condition revise