8,540 research outputs found
Long and short paths in uniform random recursive dags
In a uniform random recursive k-dag, there is a root, 0, and each node in
turn, from 1 to n, chooses k uniform random parents from among the nodes of
smaller index. If S_n is the shortest path distance from node n to the root,
then we determine the constant \sigma such that S_n/log(n) tends to \sigma in
probability as n tends to infinity. We also show that max_{1 \le i \le n}
S_i/log(n) tends to \sigma in probability.Comment: 16 page
Search for the production of dark fermion candidates in association with heavy neutral gauge boson decaying to dimuon in proton-proton collisions at TeV using the CMS open data
This analysis shows a search for dark fermion particles produced in
association with a heavy neutral gauge boson (Z). The studied events
topology are dimuon and a large missing transverse momentum. %We considered the
muonic decay of Z. The analyzed data were the Open Data collected by
the CMS detector in proton-proton collisions at the LHC in 2012 and correspond
to an integrated luminosity of 11.6 fb at 8 TeV. One
benchmark scenario the light vector was used for interpreting the data, based
on a simplified model so called the mono-Z model. No evidence of
dark fermion candidates was found, 95 confidence level limits have been set
on both Z and dark fermion masses.Comment: 10 pages. arXiv admin note: substantial text overlap with
arXiv:2103.04326, arXiv:2109.1127
Implementing Good Practices Programs to Encourage Production of High-Quality, Safer Produce in Mississippi
Fifty-four growers/producers attended four 1-day good agricultural practices (GAP) and good handling practices (GHP) workshops at four locations in Mississippi. Pre- and postworkshop survey data indicated that the participants\u27 food safety knowledge increased by 15%. Furthermore, the workshops helped producers develop their own food safety plans. The workshops also trained the producers to be prepared for U.S. Department of Agriculture (USDA) GAP and GHP audits. To assist producers in preparing for these audits, two mock audits were conducted after the workshops. As a result of the program, several producers became ready to be audited, and at least one producer became USDA GAP certified
High-pressure behavior of superconducting boron-doped diamond
This work investigates the high-pressure structure of freestanding
superconducting ( = 4.3\,K) boron doped diamond (BDD) and how it affects
the electronic and vibrational properties using Raman spectroscopy and x-ray
diffraction in the 0-30\,GPa range. High-pressure Raman scattering experiments
revealed an abrupt change in the linear pressure coefficients and the grain
boundary components undergo an irreversible phase change at 14\,GPa. We show
that the blue shift in the pressure-dependent vibrational modes correlates with
the negative pressure coefficient of in BDD. The analysis of x-ray
diffraction data determines the equation of state of the BDD film, revealing a
high bulk modulus of =51028\,GPa. The comparative analysis of
high-pressure data clarified that the sp carbons in the grain boundaries
transform into hexagonal diamond.Comment: 7 pages, 4 figure
Low Dimensional Description of Pedestrian-Induced Oscillation of the Millennium Bridge
When it opened to pedestrian traffic in the year 2000, London's Millennium
Bridge exhibited an unwanted, large, side-to-side oscillation which was
apparently due to a resonance between the stepping frequency of walkers and one
of the bridge modes. Models for this event, and similar events on other
bridges, have been proposed. The model most directly addressing the
synchronization mechanism of individual walkers and the resulting global
response of the bridge-pedestrian system is one developed by Eckhardt et al.
This model treats individual walkers with a phase oscillator description and is
inherently high dimensional with system dimensionality (N+2), where N is the
number of walkers. In the present work we use a method proposed by Ott and
Antonsen to reduce the model of Eckhardt et al. to a low dimensional dynamical
system, and we employ this reduced description to study the global dynamics of
the bridge/pedestrian interaction. More generally, this treatment serves as an
interesting example of the possibility of low dimensional macroscopic behavior
in large systems of coupled oscillators.Comment: Submitted to Chaos Journa
Prototype tests for the ALICE TRD
A Transition Radiation Detector (TRD) has been designed to improve the
electron identification and trigger capability of the ALICE experiment at the
Large Hadron Collider (LHC) at CERN. We present results from tests of a
prototype of the TRD concerning pion rejection for different methods of
analysis over a momentum range from 0.7 to 2 GeV/c. We investigate the
performance of different radiator types, composed of foils, fibres and foams.Comment: Presented at the IEEE Nuclear Science Symposium and Medical Imaging
Conference, Lyon, October 15-20, 2000 (accepted for publication in IEEE TNS),
Latex (IEEEtran.cls), 7 pages, 11 eps figure
Design, synthesis, antitumor activity and molecular docking study of novel 5-deazaalloxazine analogs
open access articleProtein tyrosine kinases (PTKs) are the most potential therapeutic targets for cancer. Herein, we present a sound rationale for synthesis of a series of novel 2-(methylthio), 2-(substituted alkylamino), 2-(heterocyclic substituted), 2-amino, 2,4-dioxo and 2-deoxo-5-deazaalloxazine derivatives by applying structure-based drug design (SBDD) using AutoDock 4.2. Their antitumor activities against human CCRF-HSB-2, KB, MCF-7 and HeLa have been investigated in vitro. Many 5-deazaalloxazine analogs revealed high selective activities against MCF-7 tumor cell lines (IC50: 0.17–2.17 µM) over HeLa tumor cell lines (IC50 > 100 µM). Protein kinase profiling revealed that compound 3h induced multi- targets kinase inhibition including −43% against (FAK), −40% against (CDKI) and −36% against (SCR). Moreover, the Annexin-V/PI apoptotic assay elucidate that compound 3h showed 33% and potentially 140% increase in early and late apoptosis to MCF-7 cells respectively, compared to the control. The structure-activity relationship (SAR) and molecular docking study using PTK as a target enzyme for the synthesized 7-deazaalloaxazine derivatives were investigated as potential antitumor agents. The AutoDock binding affinities of the 5deazaalloxazine analogs into c-kit PTK (PDB code: 1t46) revealed reasonable correlations between their AutoDock binding free energy and IC50
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