101 research outputs found

    Comparison of Workforce Diversity in Public and Private Business Organizations

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    Potential of human resource has always been considered as at the heart of a business organization. An effective human resource can not only ignite the organizational excellence but it also is a cornerstone for the consistency of optimal level of business performance. This research paper aims at one of the most discussed areas in the literature related to human resource management called “Workforce diversity”. Right from the start of modern business practices public and private business organizations came into existence and so the difference in human resource focus of both of these types of business organizations. Focus of this study is to explore the difference among employees of both types of above mentioned business organizations keeping in view the level of workforce diversity in their respective organizations. Study is unique because it addresses the research gap found after extensive literature review. The said research gap is that no such study has been done before in literature keeping in view Pakistani business environment. Target population comprising of banking sector, health and medical services sector was studied and brought under light by taking a sample of 150 employees. In order to analyze the acquired data statistical tools like independent t test and frequency test were also applied for better results and findings. Findings of the study states that there exists huge difference among employees working in public and private sector organizations due to conception and application of workforce diversity in both of these business organization types. It was also found that middle and operational levels of workforce are more diverse in comparison with top levels of workforce. Workforce diversity is properly planned in most of the private organizations while public sector organizations are still lagging behind. Due to significantly highlighted importance of organizational performance in public sector organizations; public sector is now improving application of workforce diversity in its practices. Keywords: Workforce Diversity, Public & Private Sector, Culture, Organizational Performance

    Conceptual Metaphors in Stock Market Reports in the Malaysian Business Times

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    The purpose of this study is to identify the metaphorical linguistic expressions of conceptual metaphors in the Malaysian Business Times using Charteris-Black and Ennis’ (2001) proposed list of conceptual metaphors. This study is a non-experimental descriptive study, which uses the corpus linguistic approach for data collection and the corpus for analysis of 50 share market news reports that were randomly identified. An expert within the business context was appointed to provide expertise in the interpretation of specific types of data derived from the corpus. The findings demonstrate that the conceptual metaphors: MARKET MOVEMENTS ARE PHYSICAL MOVEMENT and THE ECONOMY IS AN ORGANISM are the most dominant conceptual metaphors found in the corpus collected. In addition, the findings show that the metaphorical linguistic expressions generally concretise the abstract concept of the economy and market movements. Findings from this study suggest that conceptual metaphors could enhance language learners’ creativity in language learning by having a better grasp of the course subjects in terms of underlying concepts of metaphors used, hence developing an understanding of how conceptual metaphors work (Sharifah Hafizah 2004). This study has also developed a step-by-step procedure in identifying metaphorical linguistic expressions. With this newly-developed method, it is hoped to facilitate future studies in identifying metaphorical linguistic expressions

    Getting physical with the market: a study of metaphors in the business times

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    This study investigates the metaphorical linguistic manifestations of the conceptual metaphor, market movements are physical movements, using Charteris-Black and Ennis’s (2001) notion of conceptual metaphors. Following a corpus linguistic approach for data collection purposes, it analysed 50 unique Business Times articles randomly identified from a total of 292 articles. An expert within the business context provided expertise in the interpretation of specific types of data derived from the corpus. The findings show that the metaphorical linguistic expressions generally concretise the abstract concept of the economy and market movements and mainly comprise of verbs and nouns. This paper illustrates some of the examples of the relevant metaphorical expressions and discusses how the domain of physical movements helps to structure the domain of market movements. The findings of this study, however, can only be generalised to the samples involved in this study

    Biosynthesis of lovastatin using agro-industrial wastes as carrier substrates

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    Purpose: To compare fungal strains including Aspergillus flavipes GCBL-72, Aspergillus flavus GCBL-60, and Aspergillus niger GCBL-45 and determine whether solid- or liquid-state fermentation (SSF or LSF) is more appropriate for lovastatin production using various inexpensive raw materials.Methods: LSF and SSF techniques were used to produce the drug lovastatin.  High-performance liquid chromatography was performed out to quantify lovastatin production. A kinetic growth model was applied to estimate product formation at the expense of substrate utilization.Results: Aspergillus flavus GCBL-60 was a superior lovastatin-producing strain consuming wheat bran as the raw material in SSF. The optimum lovastatin production was 28.36 ± 0.76 mg/100mL at 35 °C, pH 5.5, inoculum size 2 mL, 96 h incubation time, and 60 % moisture content. Evaluation of the kinetic growth parameters for lovastatin production confirmed that product formation was improved after fermentation parameter optimization.Conclusion: Our results indicate that Aspergillus flavus GCBL-60 was best  lovastatin-producing strain and that SSF was superior to LSF for maximum  production. Careful optimization can enhance product formation.Keywords: Hypercholesterolemia, Kinetics, Optimization, Lovastatin, Solid-State Fermentation, Raw material

    Corporate Governance and Prospect Theory: A Case Study of Pakistan

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    Risk averse and risk seeking attitude of individuals is advocated by the Prospect Theory. Its application has also been examined at the organizational level. This study grants extension to the work already conducted by researchers in which application of prospect theory has been examined in the contextual framework of corporate sector of Pakistan, by evaluating whether irrational behavior of the prospect theory is applicable in capital investment decisions of companies in Pakistan. Previous results have been used in the present study in order to examine the implications of corporate governance for controlling these risk-averse and risk-seeking attitudes. Data set of this study, consist of 139 non-financial companies listed with the Karachi Stock Exchange (KSE), during the period of 2006 to 2011. It has been found that risk- averse attitude of companies is controlled by good corporate governance when Return on Assets (ROA) was used as a measure of companies’ financial performance; whereas, it has helped in controlling such behavior partly when Return on Equity (ROE) was used as a measure of financial performance. However, it has all together no effect on risk seeking attitude of companies. Findings of this study are similar in both measures of financial performance, i.e., ROA and ROE. Thus, this study creates a nexus between behavioral finance and corporate governance

    Salivary microRNA 155, 146a/b and 203: A pilot study for potentially non-invasive diagnostic biomarkers of periodontitis and diabetes mellitus

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    Dysregulated expression of MicroRNAs (miRNAs) plays substantial role in the initiation and progression of both diabetes and periodontitis. The aim of the present study was to validate four miRNAs in saliva as potential predictive biomarkers of periodontal disease among patients with and without diabetes mellitus (DM). MiRNAs were extracted from the saliva of 24 adult subjects with DM and 29 healthy controls. Each group was subdivided into periodontally healthy or having periodontitis. In silico analysis identified 4 miRNAs (miRNA 155, 146 a/b and 203) as immune modulators. The expression of miRNAs-146a/b, 155, and 203 was tested using quantitative PCR. The expression levels in the study groups were compared to explore the effect of diabetes on periodontal status and vice versa. In our cohort, the four miRNAs expression were higher in patients with periodontitis and/or diabetes. miRNA-155 was the most reliable predictors of periodontitis among non-diabetics with an optimum cut-off value of < 8.97 with accuracy = 82.6%. MiRNA 146a, on the other hand, was the only reliable predictor of periodontitis among subjects with diabetes with optimum cut-off value of ≥11.04 with accuracy = 86.1%. The results of the present study concluded that MiRNA-146a and miRNA155 in saliva provide reliable, non-invasive, diagnostic and prognostic biomarkers that can be used to monitor periodontal health status among diabetic and non-diabetic patients

    Effect of visible range electromagnetic radiations on Escherichia coli

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    Background: Escherichia coli is the agent responsible for a range of clinical diseases. With emerging antimicrobial resistance, other treatment options including solar/photo-therapy are becoming increasingly common. Visible Range Radiation Therapy/Colour Therapy is an emerging technique in the field of energy/vibrational medicine that uses visible spectrum of Electromagnetic Radiations to cure different diseases. In this study, our goal was to understand the effect of Visible Range Electromagnetic Radiations on E. coli (in vitro) and therefore find out the most appropriate visible range radiation for the treatment of diseases caused by E. coli.Materials and Methods: A total of 6 non-repetitive E. coli isolates were obtained from urine samples obtained from hospitalized patients with UTI. Single colony of E. coli was inoculated in 3 ml of Lysogeny Broth (LB) and 40 μl of this E. coli suspension was poured into each of the plastic tubes which were then irradiated with six different wavelengths in the visible region (Table. 1) after 18 hours with one acting as a control. The Optical Densities of these irradiated samples were then measured. Furthermore, scanning electron microscopy (TEFCAN ZEGA3) was carried out.Results: The analysis of the microscopic and SEM images of irradiated E. coli samples with six different visible range radiations is representative of The fact that E. coli responded differently to every applied radiation in the visible region and the most profound inhibitory effects were that of 538nm Visible Range Radiation (Green) which proved to be bactericidal and 590nm Visible Range Radiation (yellow) which was bacteriostatic. The enhanced growth of E. coli with varying degrees was clearly observed in 610nm (orange), 644nm (red), 464nm (Purple) and 453nm (blue).Conclusion: It can be concluded that 538nm (Green) and 590nm (Yellow) can effectively be used for treating E. coli borne diseases.Keywords: Visible Range Radiation Therapy, E. coli, UTI, Alternative Treatment, Colour Therap

    Role of Lysyl oxidase-like 1 gene polymorphisms in Pakistani patients with pseudoexfoliative glaucoma

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    Contains fulltext : 109429.pdf (publisher's version ) (Open Access)PURPOSE: Single nucleotide polymorphisms (SNPs) rs1048661 (p.R141L) and rs3825942 (p.G153D) in the lysyl oxidase-like 1 (LOXL1) gene have been previously reported to be associated with pseudoexfoliation glaucoma (PEXG) in various Asian and European populations, but these SNPs have not yet been studied in the Pakistani population. Therefore the aim of the present study was to investigate the association of these two coding LOXL1 SNPs in Pakistani PEXG patients. METHODS: One hundred twenty-eight Pakistani patients diagnosed with PEXG and 180 healthy controls were recruited for the study. Genomic DNA was extracted and both SNPs were genotyped by direct sequencing. Association of genotype and allele frequencies with PEXG were analyzed using the Chi-square (chi(2)) test. RESULTS: Genotype and allele frequencies of both rs1048661 and rs3825942 were found to be significantly associated with PEXG. The GG genotypes of both LOXL1 SNPs were associated with an increased risk of developing PEXG. In addition the G alleles of rs1048661 and rs3825942 confer an increased risk for PEXG with an odds ratio (OR) of 2.98 (95% CI 1.94-4.57) and OR 6.83 (95% CI 2.94-16.67), respectively. CONCLUSIONS: A significant association was found for the G allele of rs1048661 and rs3825942 in PEXG patients of Pakistani origin

    Investigation of blaIMP-1, blaVIM-1, blaOXA-48 and blaNDM-1 carbapenemase encoding genes among MBL-producing Pseudomonas aeruginosa

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    Pseudomonas aeruginosa (P. aeruginosa) places among major opportunistic nosocomial pathogen which has developed extensive drug resistance. Due to uncontrolled consumption of antibiotics, multidrug-resistant (MDR) P. aeruginosa species are increasingly isolated from various settings of hospitals globally. This research aimed to determine the genes reproducing blaOXA-48, blaIMP-1, blaVIM-1 and blaNDM-1 metallo beta lactamase (MBL) genes from MDR P. aeruginosa isolates. Herein, the isolates of 200 P. aeruginosa have been obtained from microbiology laboratory of burn ward. The antibiotic susceptibility profile was using Disc Diffusion Method (DDM and in compliance with CLSI (Clinical and Laboratory Standards Institute) advice. Study of MBL-bearing strains and the existence of encoding genes was specified by means of polymerase chain reaction. In addition, pulsed field gel electrophoresis (PFGE) is performed for typing. In this study, 124 (62%) were extended spectrum β-lactamase producer and 51 (25.5%) were MBL producers. Moreover, 148 (74%) isolates were MDR-P. aeruginosa. Additionally, 42 (21%), 21 (10%), 10 (5%) and 2 (1%) isolates carried the blaIMP-1, blaOXA-48, blaVIM-1 and blaNDM-1 genes, respectively. The PFGE showed no genetic relationships among isolates. The study observed high rate of MDR P. aeruginosa in hospital settings, though not being outbreak, which nearly half of them carried carbapenemase enzymes. Therefore, the proper control of related infections and appropriate prescription and consumption of antibiotics is essential

    Amelioration of paracetamol-induced hepatotoxicity in rat by the administration of methanol extract of Muntingia calabura L. leaves

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    Muntingia calabura L. is a tropical plant species that belongs to the Elaeocarpaceae family. The present study is aimed at determining the hepatoprotective activity of methanol extract of M. calabura leaves (MEMC) using two models of liver injury in rats. Rats were divided into five groups (n = 6) and received 10% DMSO (negative control), 50 mg/kg N-acetylcysteine (NAC; positive control), or MEMC (50, 250, and 500 mg/kg) orally once daily for 7 days and on the 8th day were subjected to the hepatotoxic induction using paracetamol (PCM). The blood and liver tissues were collected and subjected to biochemical and microscopical analysis. The extract was also subjected to antioxidant study using the 2,2-diphenyl-1-picrylhydrazyl-(DPPH) and superoxide anion-radical scavenging assays. At the same time, oxygen radical antioxidant capacity (ORAC) and total phenolic content were also determined. From the histological observation, lymphocyte infiltration and marked necrosis were observed in PCM-treated groups (negative control), whereas maintenance of hepatic structure was observed in group pretreated with N-acetylcysteine and MEMC. Hepatotoxic rats pretreated with NAC or MEMC exhibited significant decrease (P < 0.05) in ALT and AST enzymes level. Moreover, the extract also exhibited good antioxidant activity. In conclusion, MEMC exerts potential hepatoprotective activity that could be partly attributed to its antioxidant activity and, thus warrants further investigations
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