Career Guidance for Unaccompanied Young Migrants. A Report on an Italian Experience

Unaccompanied foreign minors are migrant children without their parents, relatives, or other adults. In Italy, especially in Sicily, an increasing number of young, non-European Union foreigners arrive daily in search of a new life and work opportunities. Despite this increasing phenomenon, interventions to support young migrants in career projects are infrequent and occasional within the host communities. With the aim of developing a career guidance intervention suitable for unaccompanied foreign minors, we propose a case study presenting a career guidance intervention for a group of unaccompanied foreign adolescents. The framework is the life design paradigm. The conductors of the activities were career counsellors, with the support of a cultural mediator and/or an educator. The setting of the interventions was individual and small groups. The instruments and procedures were predominantly qualitative. This paper includes a discussion of the strengths and weakness of this intervention, including the results of the post-intervention evaluation and the follow-up after one year

Ganadería en humedales: Respuestas de la vegetación a la exclusión del pastoreo en tres tipos de ambientes en un paisaje del Delta del Paraná

Los herbívoros pueden influir profundamente sobre la estructura y funcionamiento de los ecosistemas, impactando tanto sobre el ambiente físico como sobre las comunidades vegetales y animales. Se estudió la respuesta de la vegetación luego de la exclusión del pastoreo por ganado doméstico, antes y después de una inundación prolongada, analizando la composición florística, la diversidad y la dinámica de la biomasa aérea verde en tres tipos de ambientes localizadas en distintas porciones de un gradiente topográfico (albardón, media loma alta y media loma baja) de un paisaje de humedales en el Delta del río Paraná. El pastoreo produjo un efecto sobre los parámetros de las comunidades estudiadas mientras que con la exclusión se observó una tendencia a la recuperación de la fisonomía de los ambientes originales. Asimismo los datos del período post inundación muestran que el pastoreo junto a este evento tuvieron un efecto negativo sinérgico que afectó el incremento de la biomasa de la especie dominante (Hymenachne pernambucense) y de alto valor forrajero para la media loma baja y provocó la disminución de la diversidad para las otras coberturas. Las diferencias en la biomasa viva estuvieron influenciadas tanto por la dinámica de las propias comunidades como por la herbivoría de especies palatables. Los datos generados en este trabajo son de gran valor considerando que aún no existen registros para la región y son poco los antecedentes en humedales fluviales. Además, estos resultados conjuntamente con los que se continuaron realizando a partir del año 2011 generarán una importante base de información de utilidad para establecer pautas de manejo que contribuyan al establecimiento de un sistema ganadero sustentable para la región.Herbivores may profoundly influence on structure and functioning of ecosystems impacting on physical environment and plants and animals communities. The effect of livestock grazing, by exclusion, on floristic composition, diversity and aboveground biomass dynamic were studied on three environments located in different portions of topographical gradient (levee, high mid-slope and down mid-slope) in a wetland of the Paraná river Delta. In addition, these systems were analyzed for pre and post flood period. Cattle grazing had an effect on studied communities and biomass, while with exclusion was observed, despite the short period, a tendency to recover the features of the original environments. Also the post flood period data show that grazing next to this event had a negative synergistic effect that influenced on the growth of the dominant specie (Hymenachne pernambucense) with high forage value in down mid-slope and caused the decrease of diversity for the others coverages. The differences in green biomass were influenced by the dynamics of communities than the herbivory of palatable species. The data generated in this work are great value considering that yet there are no records for this region and the background in riverine wetlands are few. In addition along with the work we are performing. Furthermore, these results together with those who continued to perform from the year2011 will generate an important base of information useful for generating management guidelines that contribute to the establishment of a sustainable livestock system for the region.Fil: Magnano, Andrea Laura. Universidad Nacional de San Martín. Instituto de Investigación e Ingeniería Ambiental. Laboratorio de Biodiversidad, Limnología y Conservación; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vicari, Ricardo Luis. Universidad de Buenos Aires. Facultad de Cs.exactas y Naturales. Departamento de Ecología, Genética y Evolución. Laboratorio de Ecología Regional; ArgentinaFil: Astrada, Elizabeth Nora. Universidad Nacional de San Martín. Instituto de Investigación e Ingeniería Ambiental. Laboratorio de Biodiversidad, Limnología y Conservación; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Quintana, Ruben Dario. Universidad Nacional de San Martín. Instituto de Investigación e Ingeniería Ambiental. Laboratorio de Biodiversidad, Limnología y Conservación; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Evaluación de la estabilidad en el tiempo del contenido proteico en variedades de arveja

El objetivo del presente trabajo ha sido evaluar la estabilidad del contenido proteico de las variedades desarrolladas por INTA y la Facultad de Ciencias Agrarias de la Universidad Nacional de Rosario y las disponibles en el mercado, contemplando tanto el comportamiento en la producción primaria como la calidad industrial de los granos producidos a la hora de producir aislados proteicos.EEA OliverosFil: Accoroni, Cecilia. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros. Laboratorio de Agroindustria; ArgentinaFil: Magnano, Luciana. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros; ArgentinaFil: Espósito, María Andrea. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria Oliveros; Argentin

Novel targeted drugs for follicular and marginal zone lymphoma: a comprehensive review

Although mostly incurable, indolent non-Hodgkin lymphomas (iNHL) are chronic diseases with a median overall survival approaching 20 years. In recent years, important advances in the knowledge of the biology of these lymphomas have led to the development of new drugs, mostly chemotherapy-free, with promising outcomes. With a median age of around 70 years at diagnosis, many patients with iNHL suffer from comorbid conditions that may limit treatment options. Therefore, nowadays, in the transition towards personalized medicine, several challenges lie ahead, such as identifying predictive markers for the selection of treatment, the adequate sequencing of available therapies, and the management of new and accumulated toxicities. In this review, we include a perspective on recent therapeutic advances in follicular and marginal zone lymphoma. We describe emerging data on approved and emerging novel therapies, such as targeted therapies (PI3K inhibitors, BTK inhibitors, EZH2 inhibitors), monoclonal antibodies and antibody-drug conjugates. Finally, we describe immune-directed approaches such as combinations with lenalidomide or the even more innovative bispecific T-cell engagers and chimeric antigen receptor T-cell therapy, which can achieve a high rate of durable responses with manageable toxicities, further obviating the need for chemotherapy

UHV Deposition and Characterization of a Mononuclear Iron(III) \u3b2-diketonate Complex on Au(111)

The adsorption of the sterically hindered \u3b2-diketonate complex Fe(dpm)3, where Hdpm = dipivaloylmethane, on Au(111) was investigated by ultraviolet photoelectron spectroscopy (UPS) and scanning tunnelling microscopy (STM). The high volatility of the molecule limited the growth of the film to a few monolayers. While UPS evidenced the presence of the \u3b2-diketonate ligands on the surface, the integrity of the molecule on the surface could not be assessed. The low temperature STM images were more informative and at submonolayer coverage they showed the presence of regular domains characterized by a flat morphology and height of 480.3 nm. Along with these domains, tetra-lobed features adsorbed on the kinks of the herringbone were also observed. DFT-simulated images of the pristine molecule and its possible decomposition products allowed to assess the partial fragmentation of Fe(dpm)3 upon adsorption on the Au(111) surface. Structural features with intact molecules were only observed for the saturation coverage. An ex situ prepared thick film of the complex was also investigated by X-ray magnetic circular dichroism (XMCD) and features typical of high-spin iron(III) in octahedral environment were observed

Anti-vascular endothelial growth factor monotherapy or combined with verteporfin photodynamic therapy for retinal angiomatous proliferation: a systematic review with meta-analysis

: Purpose: To assess functional and anatomical outcomes of intravitreal anti-Vascular Endothelial Growth Factor (anti-VEGF) monotherapy versus combined with verteporfin Photodynamic Therapy (PDT) for Retinal Angiomatous Proliferation (RAP). Methods: Studies reporting outcomes of intravitreal anti-VEGF monotherapy and/or in combination with verteporfin PDT in RAP eyes with a follow-up ≥ 12 months were searched. The primary outcome was the mean change in best corrected visual acuity (BCVA) at 12 months. Mean change in central macular thickness (CMT) and mean number of injections were considered as secondary outcomes. The mean difference (MD) between pre- and post-treatment values was calculated along with 95% Confidence Interval (95% CI). Meta-regressions were performed to assess the influence of anti-VEGF number of injections on BCVA and CMT outcomes. Results: Thirty-four studies were included. A mean gain of 5.16 letters (95% CI = 3.30-7.01) and 10.38 letters (95% CI = 8.02-12.75) was shown in the anti-VEGF group and combined group, respectively (anti-VEGF group vs. combined group, p < 0.01). A mean CMT reduction of 132.45 µm (95% CI = from -154.99 to -109.90) and 213.93 µm (95% CI = from -280.04 to -147.83) was shown in the anti-VEGF group and combined group, respectively (anti-VEGF group vs. combined group, p < 0.02). A mean of 4.9 injections (95% CI = 4.2-5.6) and 2.8 injections (95% CI = 1.3-4.4) were administered over a 12-month period in the anti-VEGF group and combined group, respectively. Meta-regression analyses showed no influence of injection number on visual and CMT outcomes. High heterogeneity was found across studies for both functional and anatomical outcomes. Conclusion: A combined approach with anti-VEGF and PDT could provide better functional and anatomical outcomes in RAP eyes compared with anti-VEGF monotherapy

Role of Management Strategies in Reducing Mortality From Invasive Fungal Disease in Children With Cancer or Receiving Hemopoietic Stem Cell Transplant

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The relationship between subjective risk intelligence and courage with working performance : the potential mediating effect of workplace social courage

Background: There is a growing attention toward the construct of courage from a psychological point of view; recently, courage has been related with numerous positive individual behaviors and outcomes, such as coping strategies and subjective wellbeing, and an increasing number of studies explore the role of courage in the working and organizational environments. The present study is aimed to analyze the effect that individual courage—together with risk intelligence—and workplace social courage have on working performance; Methods: The participants are 961 Italian workers, balanced by gender; the measures used are: Courage, Subjective Risk Intelligence Scale, Workplace Social Courage Scale, and Performance Scale. Data were analyzed using Structural Equation Models; Results: The results show the effect of subjective risk intelligence and courage on working performance, both directly and through the mediation of workplace social courage; Conclusions: Suggestions for further research and practical implications are discussed