Chapter 15- Things are Different Now A Student, Staff, and Faculty Course Design Institute Collaboration

Like other institutions across the world, Georgetown University in Washington, DC switched to remote learning in March 2020 as the COVID-19 pandemic hit the United States. Our Center for New Designs in Learning and Scholarship (CNDLS), which serves as both a center for teaching and learning as well as a center for technology innovation, responded quickly with a series of offerings to prepare and support faculty to teach remotely. Options included a virtual conference on digital pedagogy, a series of cohort-based Course Design Institutes (CDI) throughout the summer where faculty engaged with intertwined principles and best practices from inclusive pedagogy and online course design; and a series of workshops on select teaching topics. As with so many other centers for teaching and learning, we saw a rapid increase in faculty participation as instructors planned for fall 2020 remote courses. We worked with over 1,800 unique faculty through our summer conference, CDIs, and other engagements

An interprofessional nurse-led mental health promotion intervention for older home care clients with depressive symptoms.

BackgroundDepressive symptoms in older home care clients are common but poorly recognized and treated, resulting in adverse health outcomes, premature institutionalization, and costly use of health services. The objectives of this study were to examine the feasibility and acceptability of a new six-month interprofessional (IP) nurse-led mental health promotion intervention, and to explore its effects on reducing depressive symptoms in older home care clients (≥ 70 years) using personal support services.MethodsA prospective one-group pre-test/post-test study design was used. The intervention was a six-month evidence-based depression care management strategy led by a registered nurse that used an IP approach. Of 142 eligible consenting participants, 98 (69%) completed the six-month and 87 (61%) completed the one-year follow-up. Outcomes included depressive symptoms, anxiety, health-related quality of life (HRQoL), and the costs of use of all types of health services at baseline and six-month and one-year follow-up. An interpretive descriptive design was used to explore clients', nurses', and personal support workers' perceptions about the intervention's appropriateness, benefits, and barriers and facilitators to implementation.ResultsOf the 142 participants, 56% had clinically significant depressive symptoms, with 38% having moderate to severe symptoms. The intervention was feasible and acceptable to older home care clients with depressive symptoms. It was effective in reducing depressive symptoms and improving HRQoL at six-month follow-up, with small additional improvements six months after the intervention. The intervention also reduced anxiety at one year follow-up. Significant reductions were observed in the use of hospitalization, ambulance services, and emergency room visits over the study period.ConclusionsOur findings provide initial evidence for the feasibility, acceptability, and sustained effects of the nurse-led mental health promotion intervention in improving client outcomes, reducing use of expensive health services, and improving clinical practice behaviours of home care providers. Future research should evaluate its efficacy using a randomized clinical trial design, in different settings, with an adequate sample of older home care recipients with depressive symptoms.Trial registrationClinicaltrials.gov identifier: NCT01407926

The uncharacteristic occurrence of the June 2013 biomass-burning haze event in Southeast Asia: effects of the Madden-Julian oscillation and tropical cyclone activity.

One of the worst haze events to ever hit Peninsular Malaysia occurred in June 2013 due to smoke from Riau, Central Sumatra. While biomass-burning in the region is common, the early occurrence of a haze episode of this magnitude was uncharacteristic of the seasonality of extreme fire events, which usually occur between August and October in the Maritime Continent (MC). This study aims to investigate the phenomenology of the June 2013 haze event and its underlying meteorological forcing agents. The aerosol and meteorological environment during the event is examined using the Moderate Resolution Imaging Spectroradiometer (MODIS) active fire hotspot detections and aerosol optical thickness retrievals, satellite-based precipitation retrievals, and meteorological indices. These datasets are then supported by a WRF-Chem simulation to provide a comprehensive picture of the event's meteorology and aerosol transport phenomenology. While extreme fire events are more characteristic of El Nino years, the MODIS fire count over the MC in June for the years 2001–2015 was highest in 2013 when neutral El Nino/Southern Oscillation (ENSO) conditions prevailed. Although, the mean daily precipitation for June 2013 was below average for June 2003–2015. An early active tropical cyclone (TC) season occurred in 2013, and results show that the combined induced subsidence and flow enhancement due to TC Bebinca and the dry phases of a strong Madden–Julian Oscillation (MJO) event contributed to the event intensification. Results also show that Bebinca induced a decrease in surface relative humidity of at least 10% over Riau, where fire hotspots were concentrated

Preparation of highly and generally enriched mammalian tissues for solid state NMR.

An appreciable level of isotope labelling is essential for future NMR structure elucidation of mammalian biomaterials, which are either poorly expressed, or unexpressable, using micro-organisms. We present a detailed protocol for high level (13)C enrichment even in slow turnover murine biomaterials (fur keratin), using a customized diet supplemented with commercial labelled algal hydrolysate and formulated as a gel to minimize wastage, which female mice consumed during pregnancy and lactation. This procedure produced approximately eightfold higher fur keratin labelling in pups, exposed in utero and throughout life to label, than in adults exposed for the same period, showing both the effectiveness, and necessity, of this approach.The authors would like to acknowledge funding from the Biotechnology and Biological Sciences Research Council for DGR and RR; Engineering and Physical Sciences Research Council for WYC and VWCW; National Institute of Health Research for RAB.This is the final version of the article. It first appeared from Springer via http://dx.doi.org/10.1007/s10858-015-9977-

Biological and economic consequences of alternative SP-ALB stock recovery trajectories

South Pacific albacore is a species of primary importance in the longline fishery of a number of Small Island Developing States in the Western and Central Pacific Ocean. Despite the fact that the stock is assessed as not being subject to overfishing, nor overfished, economic returns have declined significantly over the past decade. This has led to calls for management intervention. Given stated biological and economic objectives for the fishery, members of the Pacific Islands Forum Fisheries Agency proposed an interim stock target reference point (TRP) to the Western and Central Pacific Fisheries Commission that imply a larger stock size, higher catch rates and a more profitable fishery. The purpose of this study is to examine the biological and economic consequences along the trajectories of two distinct longline effort reduction regimes that achieve the proposed TRP within 20 years. These are a one-off effort reduction implemented immediately, and a phased reduction under which effort is reduced by a fixed percent each year. The results will be discussed in the light of wider Pacific Island objectives for fishery production and fleet profitability

What is the 'problem' that outreach work seeks to address and how might it be tackled? Seeking theory in a primary health prevention programme

<b>Background</b> Preventive approaches to health are disproportionately accessed by the more affluent and recent health improvement policy advocates the use of targeted preventive primary care to reduce risk factors in poorer individuals and communities. Outreach has become part of the health service response. Outreach has a long history of engaging those who do not otherwise access services. It has, however, been described as eclectic in its purpose, clientele and mode of practice; its effectiveness is unproven. Using a primary prevention programme in the UK as a case, this paper addresses two research questions: what are the perceived problems of non-engagement that outreach aims to address; and, what specific mechanisms of outreach are hypothesised to tackle these.<p></p> <b>Methods</b> Drawing on a wider programme evaluation, the study undertook qualitative interviews with strategically selected health-care professionals. The analysis was thematically guided by the concept of 'candidacy' which theorises the dynamic process through which services and individuals negotiate appropriate service use.<p></p> <b>Results</b> The study identified seven types of engagement 'problem' and corresponding solutions. These 'problems' lie on a continuum of complexity in terms of the challenges they present to primary care. Reasons for non-engagement are congruent with the concept of 'candidacy' but point to ways in which it can be expanded.<p></p> <b>Conclusions</b> The paper draws conclusions about the role of outreach in contributing to the implementation of inequalities focused primary prevention and identifies further research needed in the theoretical development of both outreach as an approach and candidacy as a conceptual framework

The Grizzly, September 23, 2010

Biology Department Receives $1.3 Million Grant • Shorter Rush Period Impacts Thoughts Surrounding Greeks • Students Continue the Growth of the UC Organic Garden • Lecture on Protecting Manatees Highlights Human Interference • How to Become a Deep Learner • Project Pericles to Sponsor Debating for Democracy in the Berman Museum Tomorrow • Bed Bug Epidemic Hits College Campuses Across Nation • Professor Seeking Tenure: Dr. Rebecca Jaroff • Opinions: Catholic Church Taking the Next Step Towards Healing; Never-Ending Ordeal of Crossing Main Street • UC Alum Honored with Prestigious Gymnastics Accolade • UC Field Hockey: In it to Win it for \u2710 Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1818/thumbnail.jp

NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization.

Nuclear magnetic resonance (NMR) spectroscopy is useful to determine molecular structure in tissues grown in vitro only if their fidelity, relative to native tissue, can be established. Here, we use multidimensional NMR spectra of animal and in vitro model tissues as fingerprints of their respective molecular structures, allowing us to compare the intact tissues at atomic length scales. To obtain spectra from animal tissues, we developed a heavy mouse enriched by about 20% in the NMR-active isotopes carbon-13 and nitrogen-15. The resulting spectra allowed us to refine an in vitro model of developing bone and to probe its detailed structure. The identification of an unexpected molecule, poly(adenosine diphosphate ribose), that may be implicated in calcification of the bone matrix, illustrates the analytical power of this approach

Mechanical adaptation of brachiopod shells via hydration-induced structural changes.

The function-optimized properties of biominerals arise from the hierarchical organization of primary building blocks. Alteration of properties in response to environmental stresses generally involves time-intensive processes of resorption and reprecipitation of mineral in the underlying organic scaffold. Here, we report that the load-bearing shells of the brachiopod Discinisca tenuis are an exception to this process. These shells can dynamically modulate their mechanical properties in response to a change in environment, switching from hard and stiff when dry to malleable when hydrated within minutes. Using ptychographic X-ray tomography, electron microscopy and spectroscopy, we describe their hierarchical structure and composition as a function of hydration to understand the structural motifs that generate this adaptability. Key is a complementary set of structural modifications, starting with the swelling of an organic matrix on the micron level via nanocrystal reorganization and ending in an intercalation process on the molecular level in response to hydration