9 research outputs found
Relación entre calidad y coste de la prescripción farmacológica en atención primaria
ObjetivoAnalizar la prescripcion farmaceutica de los medicos generales (MG) segun un sistema de indicadores cualitativos y evaluar la relacion de estos con el gasto global de prescripcion farmaceutica por habitante.DisenoEstudio descriptivo, retrospectivo.EmplazamientoAtencion primaria.Mediciones y resultados principalesSe evalua la prescripcion farmaceutica de 285 MG de 32 equipos de atencion primaria, siendo la prescripcion individual de cada medico la unidad de analisis. La prescripcion se clasifico en 3 categorias segun su valor intrinseco (%VIF): bajo (. 75%), medio (76–79%) y alto (. 80%). Como trazadores de hiperprescripcion fueron seleccionados: DHD antibioticos (AB), DHD antiinflamatorios no esteroides (AINE) y DHD antiulcerosos (ULC), y como trazadores de seleccion: %DHD cefalosporinas tercera generacion/DHD cefalosporinas totales (CEF3.aG), %DHD quinolonas amplio espectro/DHD quinolonas totales (QAP), %DHD AINE/DHD (AINE + analgesicos) (ANAL). Los indicadores cuantitativos estudiados fueron: gasto total/poblacion asignada (GPA), coste/receta farmacos de eficacia dudosa y coste/DDD de AB, AINE y ULC. Se aplico el analisis de variancia, incluyendo la prueba de Scheffe para comparaciones multiples y la correlacion lineal de Pearson. Un 26% de las prescripciones tenia un %VIF < 75%, mientras que el 34% lo tenia > 80%. Las medias de DHD AB entre las categorias de VIF eran diferentes (p < 0,0001), al igual que las de DHD de AINE (p < 0,0001) y ULC (p = 0,007), observandose un menor consumo de AB, AINE y ULC en las prescripciones con VIF mas alto. Las CEF3aG, asi como ANAL presentan diferencias significativas con las 3 categorias de VIF (p < 0,0001 y p = 0,041) a diferencia del QAP (p = 0,18). El GPA es menor entre los MG cuyas prescripciones tenian el %VIF mas alto; en cambio, el coste/receta y el coste DDD no presentaron diferencias significativas segun categorias de %VIF.ConclusionesLos medicos con mejor perfil cualitativo segun estos indicadores presentan un menor gasto por habitante. En cambio, no se observan diferencias en el coste por receta ni en el coste/tratamiento entre los distintos medicos. Por tanto, las intervenciones deben priorizar la mejora de la calidad de la prescripcion farmaceutica antes que promover unicamente el cambio al farmaco de menor coste.ObjectivesWith a system of qualitative indicators, to analyse the pharmaceutical prescription of general practitioners (GPs), and to evaluate the relationship of these indicators to the overall pharmaceutical prescription expenditure per inhabitant.DesignRetrospective descriptive study.SettingPrimary care.Measurements and main resultsThe drugs prescription of 285 GPs from 32 primary care teams was evaluated, with the individual prescription of each doctor as the unit of analysis. The prescription was classified in 3 categories according to its intrinsic value (IV): low (. 75%), medium (76–79%) and high (. 80%). Selected as tracers of over-prescription were: daily dose per inhabitant (DDI) of antibiotics (AB), DDI of non-steroid anti-inflammatory drugs (NSAID), and DDI of ulcer drugs (ULC). Selected as tracers of selection were: % DDI third-generation cephalosporins/DDI total cephalosporins; % DDI broad-spectre quinolones/DDI total quinolones; and % DDI NSAID/DDI NSAID plus analgesics. Quantitative indicators studied were: total expenditure per allocated population, cost per drugs prescription of doubtful efficacy, and cost per daily dose of AB, NSAID and ULC. Variance analysis, including the Scheffe test for multiple comparisons and Pearson's linear correlation, was applied. 26% of the prescriptions had an IV below 75%, and 34% had an IV above 80%. The means of DDI of AB among the categories of IV were different (p < 0.0001), as were those of DDI of NSAID (p < 0.0001) and of ULC (p = 0.007). Lower consumption of AB, NSAID and ULC was found in prescriptions with the highest IV %. The third-generation cephalosporins and the NSAID + analgesics showed significant differences in the three IV categories (p < 0.0001 and p = 0.041), unlike broad-spectrum quinolones (p = 0.18). The total expenditure per allocated population was less for GPs whose prescriptions had the highest IV %; whereas the cost per prescription and cost per daily dose showed no significant differences for IV categories.ConclusionsThe doctors with the best qualitative profile on these indicators had less expenditure per inhabitant. However, no differences were found in the cost per prescription or cost per treatment between doctors. Therefore, interventions must prioritise improving drug prescription quality rather than just promoting changes to lower-cost drugs
Impact of pharmaceutical promotion on prescribing decisions of general practitioners in Eastern Turkey
<p>Abstract</p> <p>Background</p> <p>Commercial sources of information are known to have greater influence than scientific sources on general practitioners' (GPs) prescribing behavior in under developed and developing countries. The study aimed to determine the self-reported impact of pharmaceutical promotion on the decision-making process of prescription of GPs in Eastern Turkey.</p> <p>Methods</p> <p>A cross-sectional, exploratory survey was performed among 152 GPs working in the primary health centers and hospitals in Erzurum province of Eastern Turkey in 2006. A self-administered structured questionnaire was used. The questionnaire included questions regarding sociodemographics, number of patients per day, time per patient, frequency of sales representative visits to GPs, participation of GPs in training courses on prescribing (in-service training, drug companies), factors affecting prescribing decision, reference sources concerning prescribing and self-reported and self-rated effect of the activities of sales representatives on GPs prescribing decisions.</p> <p>Results</p> <p>Of 152 subjects, 53.3% were male and 65.8% were working at primary health care centers, respectively. Mean patient per day was 58.3 ± 28.8 patients per GP. For majority of the GPs (73.7%), the most frequent resource used in case of any problems in prescribing process was drug guides of pharmaceutical companies. According to self-report of the GPs, their prescribing decisions were affected by participation in any training activity of drug companies, frequent visits by sales representatives, high number of patient examinations per day and low year of practice (p < 0.05 for all).</p> <p>Conclusion</p> <p>The results of this study suggest that for the majority of the GPs, primary reference sources concerning prescribing was commercial information provided by sales representatives of pharmaceutical companies, which were reported to be highly influential on their decision-making process of prescribing by GPs. Since this study was based on self-report, the influence reported by the GPs may have been underestimated.</p
Assessing the effectiveness and cost-effectiveness of audit and feedback on physician’s prescribing indicators: study protocol of a randomized controlled trial with economic evaluation
The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry
Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes
The management of patients with venous thromboembolism in Italy: insights from the PREFER in VTE registry
Venous thromboembolism (VTE) is the third most common cardiovascular disease. Real-life data on the clinical presentation, risk factors, diagnosis, and treatment of VTE in Italy and Europe are required to optimize the management of this disease. The PREFER in VTE registry, a prospective non-interventional real-life study, was designed to assess clinical characteristics and management of patients with VTE, use of health care resources, and on-treatment patient quality of life. Eligible consecutive patients with objectively diagnosed VTE were enrolled in the registry and followed up for 12 months. Between January and December 2013, 816 Italian and 1027 patients from 6 European countries other than Italy (European patients) were enrolled in the registry, and followed up until December 2014. Italian patients were the oldest (mean age 65.7 years) among the European patients. The Italian patients with a history of cancer were 24.6 % of whom 63.2 % had an active cancer (18.2 and 57.0 %, respectively, in Europe). Parenteral heparin was given, as initial treatment, in 73.8 % of Italian patients (66.4 % in Europe); VKA in combination with other treatments in 45.8 % (34.7 % in Europe); and VKA as the only anticoagulant treatment in 24.4 % (17.2 % in Europe). Of the Italian patients, 43.2 and 90.6 % of patients were hospitalized for deep vein thrombosis and pulmonary embolism, respectively; 65.4 % were admitted to the hospital through the emergency department. Following a real world approach, PREFER in VTE shows that the Italian patients, among and compared to the European patients, are the oldest, have a history of cancer more commonly, receive an initial treatment with heparin more commonly, and are more commonly hospitalized, particularly if affected by PE