RCD: Rapid Close to Deadline Scheduling for Datacenter Networks

Datacenter-based Cloud Computing services provide a flexible, scalable and yet economical infrastructure to host online services such as multimedia streaming, email and bulk storage. Many such services perform geo-replication to provide necessary quality of service and reliability to users resulting in frequent large inter- datacenter transfers. In order to meet tenant service level agreements (SLAs), these transfers have to be completed prior to a deadline. In addition, WAN resources are quite scarce and costly, meaning they should be fully utilized. Several recently proposed schemes, such as B4, TEMPUS, and SWAN have focused on improving the utilization of inter-datacenter transfers through centralized scheduling, however, they fail to provide a mechanism to guarantee that admitted requests meet their deadlines. Also, in a recent study, authors propose Amoeba, a system that allows tenants to define deadlines and guarantees that the specified deadlines are met, however, to admit new traffic, the proposed system has to modify the allocation of already admitted transfers. In this paper, we propose Rapid Close to Deadline Scheduling (RCD), a close to deadline traffic allocation technique that is fast and efficient. Through simulations, we show that RCD is up to 15 times faster than Amoeba, provides high link utilization along with deadline guarantees, and is able to make quick decisions on whether a new request can be fully satisfied before its deadline.Comment: World Automation Congress (WAC), IEEE, 201

A Design Support System for Crew System Automation

[[abstract]]The authors present a structured design methodology for automation requirements analysis, specification, prototype design, and product development, and describe the design and software implementation of a design support system for crew system automation that incorporates multidisciplinary computer-aided design and engineering procedures, tools, databases, and models. Future enhancements that impact the effectiveness and efficiency of designs produced using such a computer-aided engineering tool are discussed and contrasted with the labor-intensive manual methods of today. The major benefits of the design process and design support tools are summarized. Particular attention is given to the use of the modified Petri-net formalism. The capability of the expert model-based design methodology and the prototype design support systems to produce a superior crew system design are currently being demonstrated and evaluated in conjunction with a full-mission manned system simulation[[fileno]]2020419030008[[department]]工工

Intelligent interface for remote supervision and control of underwater manipulation

[[abstract]]An intelligent human-machine interface is presented for effective management and control of underwater manipulator tasks. It is suggested as a means of both enhancing the operator-manipulator performance and reducing the overall workload and effort required by the operator. An illustrative example is presented in the form of a high-level operator-oriented command language[[fileno]]2020419030006[[department]]工工

Performance comparison of heuristic algorithms for task scheduling in IaaS cloud computing environment

Cloud computing infrastructure is suitable for meeting computational needs of large task sizes. Optimal scheduling of tasks in cloud computing environment has been proved to be an NP-complete problem, hence the need for the application of heuristic methods. Several heuristic algorithms have been developed and used in addressing this problem, but choosing the appropriate algorithm for solving task assignment problem of a particular nature is difficult since the methods are developed under different assumptions. Therefore, six rule based heuristic algorithms are implemented and used to schedule autonomous tasks in homogeneous and heterogeneous environments with the aim of comparing their performance in terms of cost, degree of imbalance, makespan and throughput. First Come First Serve (FCFS), Minimum Completion Time (MCT), Minimum Execution Time (MET), Maxmin, Min-min and Sufferage are the heuristic algorithms considered for the performance comparison and analysis of task scheduling in cloud computing

In-vivo Kinetics of Silymarin (Milk Thistle) on Healthy Male Volunteers

Purpose: The study was aimed at evaluating the in vivo kinetics of silymarin tablets, a product with antihepatotoxic and free radical scavenging activities.Methods: Silimarin® (Amson Vaccines & Pharma Pvt Ltd) was used as the test product while another silymarin tablet brand, Silliver® (Abbott Laboratories Pak Ltd) was the reference product. The tablets were administered to healthy male volunteers orally at a dose of 200 mg following an overnight fast according to a randomized cross-over design. Scheduled blood samples were collected, centrifuged and the plasma assayed using a sensitive and validated reversed phase high performance liquid chromatographic (RP-HPLC) method. Various pharmacokinetic parameters were calculated based on the non-compartmental model.Results: Non-significant difference (p < 0.05) was observed in the area under the curve (AUC) of the two brands with values of 10.8 ± 0.4 μg h/ml and 11.2 ± 0.7 μg h/ml, respectively. There was, however, a significant difference (p < 0.05) in the Cmax of the two brands. Other pharmacokinetic parameters evaluated did not show any statistical difference (p < 0.05) between the two products except for meanresidence time Conclusion: The test product can be used as an alternative to the brand, Silliver®-Abbot (reference), only in conditions where maximum plasma concentration (Cmax) is not an important consideration

Management of oesophageal foreign bodies

AbstractObjectiveThe aim of the study was to evaluate the management of foreign bodies in the oesophagus and to determine the association with socioeconomic status.MethodsThis cross-sectional analytical study was carried out in the Department of Ear, Nose and Throat and head and neck surgery of Bahawal Victoria Hospital affiliated with Quaid-i-Azam Medical College, Bahawalpur, Pakistan, between December 2012 and May 2013. The medical records of 34 consecutive cases of foreign body ingestion were searched, and the data were recorded on a questionnaire prepared for this purpose.ResultsThe average age of the patients was 10.38 years; 29 cases (85.2%) were in children under 12 years. There were 18 females (52.9%) and 16 males (47.1%). Thirty patients (88%) presented with a history of dysphagia, and 25 (73.6%) had vomiting. The site of impaction was the post-cricoid region in 22 patients (66%), the lower oesophagus in 5 (15%), the mid-oesophagus in 4 (13%), the posterior pharyngeal wall in 1 (3%) and the pyriform fossa in 1 patient (3%). Coins were the most common foreign body (61.8%). Socioeconomic analysis showed that 18 patients (52.9%) were in the low socioeconomic class, 12 (35.3%) in the middle class and 4 (11.8%) in the upper class.ConclusionThe presence of a foreign body in the oesophagus is a serious condition, and early removal is recommended. Foreign body lodgement is commoner among poor families

Development of a single combined microencapsulated formulation of allopurinol and nimesulide and investigation of their release behaviours

The aim of this study was to develop a single combined once-daily sustained release microencapsulated dosage form of Allopurinol and Nimesulide using Ethyl cellulose as release controlling factor and to evaluate drug release parameters as per various release kinetic models. In order to achieve required sustained release profile, microparticles were prepared using coacervation thermal change technique. The formulated microparticles were also characterized by physical and chemical parameters and results were found in acceptable limits. Different dissolution models were applied to drug release data in order to evaluate release mechanisms and kinetics. The drug release data fit well to the Higuchi expression. Drug release mechanism was found as a complex anomalous one

A comparison of fluoroquinolones versus other antibiotics for treating enteric fever: meta-analysis

Objectives To review evidence supporting use of fluoroquinolones as first line agents over other antibiotics for treating typhoid and paratyphoid fever (enteric fever)

A simplified model for calculating atmospheric radionuclide transport and early health effects from nuclear reactor accidents

During certain hypothetical severe accidents in a nuclear power plant, radionuclides could be released to the environment as a plume. Prediction of the atmospheric dispersion and transport of these radionuclides is important for assessment of the risk to the public from such accidents. A simplified PC-based model was developed that predicts time-integrated air concentration of each radionuclide at any location from release as a function of time integrated source strength using the Gaussian plume model. The solution procedure involves direct analytic integration of air concentration equations over time and position, using simplified meteorology. The formulation allows for dry and wet deposition, radioactive decay and daughter buildup, reactor building wake effects, the inversion lid effect, plume rise due to buoyancy or momentum, release duration, and grass height. Based on air and ground concentrations of the radionuclides, the early dose to an individual is calculated via cloudshine, groundshine, and inhalation. The model also calculates early health effects based on the doses. This paper presents aspects of the model that would be of interest to the prediction of environmental flows and their public consequences