Networked knowledge: challenges for teacher education [Editorial]

Since 1990, the World Wide Web has caused an inversion in the information economy of education. Where a traditional view of education characterized teachers as dispensers of knowledge, the second half of the twentieth century witnessed a shift towards an alternative paradigm in which knowledge is viewed as constructed by the learner from personal and shared experience. In an information-rich environment, education is likely to be less about accumulating information and more about transforming it in ways that make it more useful. Although the evolution of a networked knowledge economy may eventually require responses in many aspects of education, at least three areas are already evident. These are questions of knowledge as property attaching to concepts such as copyright and plagiarism, development of processes and skills for effective collaboration, and the problem of assessment of student learning if it is accepted that knowledge may exist in the network rather than the individual

Relation algebras from cylindric algebras, II

Accepted versio

There is no finite-variable equational axiomatization of representable relation algebras over weakly representable relation algebras

We prove that any equational basis that defines RRA over wRRA must contain infinitely many variables. The proof uses a construction of arbitrarily large finite weakly representable but not representable relation algebras whose "small" subalgebras are representable.Comment: To appear in Review of Symbolic Logi

Publishing data evidence to support educational technology claims [Editorial]

As is evident by this issue, JTATE publishes works that include rich data evidence, regardless of the method used in the research design. Detailed and careful research analyses, as well as purposeful design and construction of the write-up are critical to building a strong foundation of educational technology literature. Researchers in educational technology and technology and teacher education more specifically, who decide to follow a platinum standard for research publication, are strengthening and broadening the credibility of a relatively young field. The JTATE editors promote this line of thinking, encouraging editorial board members, reviewers, and authors to assist with this important goal

CANNABINOIDS DELTA-9-TETRAHYDROCANNABINOL (THC) AND CP55,940 ABLATE SPECIFIC CHEMOKINE AND CYTOKINE INFLAMMATORY RESPONSE IN BV-2 MOUSE MICROGLIAL CELLS ACTIVATED WITH HIV-1 PRO-INFLAMMATORY PROTEIN TAT

Despite the widespread use of Highly Active Anti-retroviral Therapy (HAART) to combat Human Immunodeficiency Virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS), HIV-Associated Neurocognitive Disorders (HANDs) still remain a dire issue. HIV can enter the brain through infected monocytes and infect microglia, the resident macrophages within that compartment. Due to its pro-inflammatory properties, HIV regulatory protein Tat (Transactivating protein) may play a role in the progression of neurocognitive disorders. The aim of this project was to determine whether the select cannabinoids THC and CP55,940 could ablate the inflammatory response on BV-2 mouse microglia cells caused by Tat. Within the constraints of the experiment, no major effects of cannabinoid treatment were observed at the level of the proteome as tested by two-dimensional gel electrophoresis . In contrast, these cannabinoids ablated the inflammatory response caused by the HIV protein Tat at the level of the secretome and at the level of gene expression. These collective observations suggest that select cannabinoids have the potential to down-regulate the elicitation of proinflammatory gene products that are engendered by the HIV protein Tat. Furthermore, the results suggest a potential for cannabinoid agonists at cannabinoid receptors to serve as adjunct ablative agents in the treatment of HIV-associated neuropathological processes