Application of ERTS-1 data to the protection and management of New Jersey's coastal environment

The author has identified the following significant results. A Coastal Zone Surveillance Program has been developed in which systematic comparisons of early ERTS-1 images and recently acquired images are regularly made to identify areas where changes have occurred. A methodology for assessing and documenting benefits has been established. Quantification of benefits has been directed toward four candidate areas: shore protection, ocean outfalls, coastal land resources, and offshore waste disposal. A refinement in the change detection analysis procedure has led to greater accuracy in spotting developmental changes in the Coastal Zone. Preliminary conclusions drawn from the Shore Erosion case study indicate that in the northern test area (developed beach) erosion has occurred more often, is generally more severe, and the beach is slower to recover than in the southern test area (natural beach). From these data it appears that it may be possible to define areas most likely to experience further erosion. The assumption of continued erosion in areas that have at one time experienced severe erosion is supported by the simple fact that as a beach narrows wave energy is concentrated on a narrower beach surface. The higher energy condition subsequently results in accelerated erosion

Application of ERTS-1 data to the protection and management of New Jersey's coastal environment

The author has identified the following significant results. Rapid access to ERTS data was provided by NASA GSFC for the February 26, 1974 overpass of the New Jersey test site. Forty-seven hours following the overpass computer-compatible tapes were ready for processing at EarthSat. The finished product was ready just 60 hours following the overpass and delivered to the New Jersey Department of Environmental Protection. This operational demonstration has been successful in convincing NJDEP as to the worth of ERTS as an operational monitoring and enforcement tool of significant value to the State. An erosion/ accretion severity index has been developed for the New Jersey shore case study area. Computerized analysis techniques have been used for monitoring offshore waste disposal dumping locations, drift vectors, and dispersion rates in the New York Bight area. A computer shade print of the area was used to identify intensity levels of acid waste. A Litton intensity slice print was made to provide graphic presentation of dispersion characteristics and the dump extent. Continued monitoring will lead to the recommendation and justification of permanent dumping sites which pose no threat to water quality in nearshore environments

MRI radiomic features are independently associated with overall survival in soft tissue sarcoma

Purpose: Soft tissue sarcomas (STS) represent a heterogeneous group of diseases, and selection of individualized treatments remains a challenge. The goal of this study was to determine whether radiomic features extracted from magnetic resonance (MR) images are independently associated with overall survival (OS) in STS. Methods and Materials: This study analyzed 2 independent cohorts of adult patients with stage II-III STS treated at center 1 (N = 165) and center 2 (N = 61). Thirty radiomic features were extracted from pretreatment T1-weighted contrast-enhanced MR images. Prognostic models for OS were derived on the center 1 cohort and validated on the center 2 cohort. Clinical-only (C), radiomics-only (R), and clinical and radiomics (C+R) penalized Cox models were constructed. Model performance was assessed using Harrell\u27s concordance index. Results: In the R model, tumor volume (hazard ratio [HR], 1.5) and 4 texture features (HR, 1.1-1.5) were selected. In the C+R model, both age (HR, 1.4) and grade (HR, 1.7) were selected along with 5 radiomic features. The adjusted c-indices of the 3 models ranged from 0.68 (C) to 0.74 (C+R) in the derivation cohort and 0.68 (R) to 0.78 (C+R) in the validation cohort. The radiomic features were independently associated with OS in the validation cohort after accounting for age and grade (HR, 2.4; Conclusions: This study found that radiomic features extracted from MR images are independently associated with OS when accounting for age and tumor grade. The overall predictive performance of 3-year OS using a model based on clinical and radiomic features was replicated in an independent cohort. Optimal models using clinical and radiomic features could improve personalized selection of therapy in patients with STS

Application of ERTS-1 data to the protection and management of New Jersey's coastal environment

The author has identified the following significant results. The principal thrust of this ERTS-1 experiment is to develop quasi-operational information products from analysis of ERTS-1 imagery and collateral aerial photography and to apply these products to the practical regulation, protection, and management of New Jersey's coastal environment. Incorporated into this goal is the development of procedures for the operational use of ERTS-1 data products within New Jersey's Department of Environmental Protection. Analysis and product preparation for operational needs has centered on four major coastal resource problem areas: detection of land use changes in the coastal zone; siting of ocean outfalls; monitoring of offshore waste disposal; and calculation of recession rates along the Atlantic Shore. The relative utility and estimated monetary benefits derived from ERTS and aircraft imagery for each problem area have been determined. Of equal importance is the development to a capability within the State to use and understand remote sensor-derived information, and the application of this information to meet the requirements of current and anticipated coastal zone legislation

Application of ERTS-1 data to the protection and management of New Jersey's coastal environment

The author has identified the following significant results. Quasi-operational information products for coastal zone management have been prepared using ERTS-1 imagery and collateral aerial photography. These products were applied to the practical regulation, protection, and management of New Jersey's coastal environment. Procedures were developed for the operational use of ERTS-1 data products within New Jersey's Department of Environmental Protection. Successful analysis and product preparation for operational needs centered on four major coastal resource problem areas: (1) detection of environmental changes in coastal areas, (2) siting of ocean outfalls, (3) monitoring of offshore waste disposal, and (4) calculation of recession rates along the Atlantic Shore. The utility and monetary benefits derived from ERTS and aircraft imagery for each problem area have been determined. The NJDEP estimates the possibility of $620,000 yearly savings through the use of an operational ERTS system and a one-time savings of$2.8 million on current or planned projects if a truly operational ERTS type satellite were available

Magnetic Resonance

Contains research objectives and reports on three research projects

Analysis of the rotation period of asteroids (1865) Cerberus, (2100) Ra-Shalom, and (3103) Eger - search for the YORP effect

The spin state of small asteroids can change on a long timescale by the Yarkovsky-O'Keefe-Radzievskii-Paddack (YORP) effect, the net torque that arises from anisotropically scattered sunlight and proper thermal radiation from an irregularly-shaped asteroid. The secular change in the rotation period caused by the YORP effect can be detected by analysis of asteroid photometric lightcurves. We analyzed photometric lightcurves of near-Earth asteroids (1865) Cerberus, (2100) Ra-Shalom, and (3103) Eger with the aim to detect possible deviations from the constant rotation caused by the YORP effect. We carried out new photometric observations of the three asteroids, combined the new lightcurves with archived data, and used the lightcurve inversion method to model the asteroid shape, pole direction, and rotation rate. The YORP effect was modeled as a linear change in the rotation rate in time d\omega /dt. Values of d\omega/ dt derived from observations were compared with the values predicted by theory. We derived physical models for all three asteroids. We had to model Eger as a nonconvex body because the convex model failed to fit the lightcurves observed at high phase angles. We probably detected the acceleration of the rotation rate of Eger d\omega / dt = (1.4 +/- 0.6) x 10^{-8} rad/d (3\sigma error), which corresponds to a decrease in the rotation period by 4.2 ms/yr. The photometry of Cerberus and Ra-Shalom was consistent with a constant-period model, and no secular change in the spin rate was detected. We could only constrain maximum values of |d\omega / dt| < 8 x 10^{-9} rad/d for Cerberus, and |d\omega / dt| < 3 x 10^{-8} rad/d for Ra-Shalom

Number-phase-squeezed few-photon state generated from squeezed atoms

This paper develops a method of manipulating the squeezed atom state to generate a few-photon state whose phase or photon-number fluctuations are prescribed at our disposal. The squeezed atom state is a collective atomic state whose quantum fluctuations in population difference or collective dipole are smaller than those of the coherent atom state. It is shown that the squeezed atom state can be generated by the interaction of atoms with a coherent state of the electromagnetic field, and that it can be used as a tunable source of squeezed radiation. A variety of squeezed states, including the photon-number squeezed state and the phase squeezed state, can be produced by manipulating the atomic state. This is owing to the fact that quantum-statistical information of the atomic state is faithfully transferred to that of the photon state. Possible experimental situations to implement our theory are discussed.Comment: 17 pages, RevTex, 14 figures, using epsf.sty, title is changed, discussion about dissipation is added, accepted for publication in Physical Review

Validation of a chloroquine-induced cell death mechanism for clinical use against malaria

An alternative antimalarial pathway of an ‘outdated’ drug, chloroquine (CQ), may facilitate its return to the shrinking list of effective antimalarials. Conventionally, CQ is believed to interfere with hemozoin formation at nanomolar concentrations, but resistant parasites are able to efflux this drug from the digestive vacuole (DV). However, we show that the DV membrane of both resistant and sensitive laboratory and field parasites is compromised after exposure to micromolar concentrations of CQ, leading to an extrusion of DV proteases. Furthermore, only a short period of exposure is required to compromise the viability of late-stage parasites. To study the feasibility of this strategy, mice malaria models were used to demonstrate that high doses of CQ also triggered DV permeabilization in vivo and reduced reinvasion efficiency. We suggest that a time-release oral formulation of CQ may sustain elevated blood CQ levels sufficiently to clear even CQ-resistant parasites

IMPROVED DISTANCES TO TYPE Ia SUPERNOVAE WITH TWO SPECTROSCOPIC SUBCLASSES

We study the observables of 158 relatively normal Type Ia supernovae (SNe Ia) by dividing them into two groups in terms of the expansion velocity inferred from the absorption minimum of the Si II 6355 line in their spectra near B-band maximum brightness. One group ("Normal") consists of normal SNe Ia populating a narrow strip in the Si II velocity distribution, with an average expansion velocity v=10,600+/-400 km/s near B maximum; the other group ("HV") consists of objects with higher velocities, v > 11,800 km/s. Compared with the Normal group, the HV one shows a narrower distribution in both the peak luminosity and the luminosity decline rate dm_{15}. In particular, their B-V colors at maximum brightness are found to be on average redder by ~0.1, suggesting that they either are associated with dusty environments or have intrinsically red B-V colors. The HV SNe Ia are also found to prefer a lower extinction ratio Rv~1.6 (versus ~2.4 for the Normal ones). Applying such an absorption-correction dichotomy to SNe Ia of these two groups remarkably reduces the dispersion in their peak luminosity from 0.178 mag to only 0.125 mag.Comment: Accepted for publication in ApJ Letters, 8 pages, 4 figures, 1 tabl