Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

[This corrects the article DOI: 10.1186/s13054-016-1208-6.]

VERGLEICH VON PARAMETERN ZUR BEURTEILUNG DES BESAMUNGSERFOLGES

International audienc

Stroke_EIT_Dataset: Publication release

UCLH Stroke EIT DatasetUCLH Stroke EIT Datasetv2.

Multi-frequency electrical impedance tomography and neuroimaging data in stroke patients

Electrical Impedance Tomography (EIT) is a non-invasive imaging technique, which has the potential to expedite the differentiation of ischaemic or haemorrhagic stroke, decreasing the time to treatment. Whilst demonstrated in simulation, there are currently no suitable imaging or classification methods which can be successfully applied to human stroke data. Development of these complex methods is hindered by a lack of quality Multi-Frequency EIT (MFEIT) data. To address this, MFEIT data were collected from 23 stroke patients, and 10 healthy volunteers, as part of a clinical trial in collaboration with the Hyper Acute Stroke Unit (HASU) at University College London Hospital (UCLH). Data were collected at 17 frequencies between 5 Hz and 2 kHz, with 31 current injections, yielding 930 measurements at each frequency. This dataset is the most comprehensive of its kind and enables combined analysis of MFEIT, Electroencephalography (EEG) and Computed Tomography (CT) or Magnetic Resonance Imaging (MRI) data in stroke patients, which can form the basis of future research into stroke classification. Design Type(s) parallel group design • case control design Measurement Type(s) brain activity measurement • nuclear magnetic resonance assay • Computed Tomography of the Brain with Contrast Technology Type(s) electrical impedance tomography • MRI Scanner • computed tomography scanner Factor Type(s) diagnosis Sample Characteristic(s) Homo sapiens • brai

Bacterial cellulose as a potential vascular graft: Mechanical characterization and constitutive model development.

Bacterial cellulose (BC) is a polysaccharide produced by Acetobacter Xylinum bacteria with interesting properties for arterial grafting and vascular tissue engineering including high-burst pressure, high-water content, high crystallinity, and an ultrafine highly pure fibrous structure similar to that of collagen. Given that compliance mismatch is one of the main factors contributing to the development of intimal hyperplasia in vascular replacement conduits, an in depth investigation of support mechanical properties of BC is required to further supporting its use in cardiovascular-grafting applications. The aim of this study was to mechanically characterize BC and also study its potential to accommodate vascular cells. To achieve these aims, inflation tests and uniaxial tensile tests were carried out on BC samples. In addition, dynamic compliance tests were conducted on BC tubes, and the results were compared to that of arteries, saphenous vein, expanded polytetrafluoroethylene, and Dacron grafts. BC tubes exhibited a compliance response similar to human saphenous vein with a mean compliance value of 4.27 × 10(-2) % per millimeter of mercury over the pressure range of 30-120 mmHg. In addition, bovine smooth muscle cells and endothelial cells were cultured on BC samples, and histology and fluorescent imaging analysis were carried out showing good adherence and biocompatibility. Finally, a method to predict the mechanical behavior of BC grafts in situ was established, whereby a constitutive model for BC was determined and used to model the BC tubes under inflation using finite element analysis

Integrated materials science facility on the SRS

The development of a new integrated materials science facility (station 9.3) on the wiggler line of the Daresbury Synchrotron Radiation Source is outlined. The facility combines instrumentation for data acquisition using both spectroscopic (XANES and EXAFS) and diffraction techniques and is optimized towards industrial applications such as catalysis and electrochemistry using in situ techniques