Pre-surgical mapping of eloquent cortex for paediatric epilepsy surgery candidates: Evidence from a review of advanced functional neuroimaging

Purpose: A review of all published evidence for mapping eloquent (motor, language and memory) cortex using advanced functional neuroimaging (functional magnetic resonance imaging [fMRI] and magnetoencephalography [MEG]) for paediatric epilepsy surgery candidates has not been conducted previously. Research in this area has predominantly been in adult populations and applicability of these techniques to paediatric populations is less established. Methods: A review was performed using an advanced systematic search and retrieval of all published papers examining the use of functional neuroimaging for paediatric epilepsy surgery candidates. Results: Of the 2,724 papers retrieved, 34 met the inclusion criteria. Total paediatric participants identified were 353 with an age range of 5 months-19 years. Sample sizes and comparisons with alternative investigations to validate techniques are small and variable paradigms are used. Sensitivity 0.72 (95% CI 0.52-0.86) and specificity 0.60 (95% CI 0.35-0.92) values with a Positive Predictive Value of 74% (95% CI 61-87) and a Negative Predictive Value of 65% (95% CI 52-78) for fMRI language lateralisation with validation, were obtained. Retrieved studies indicate evidence that both fMRI and MEG are able to provide information lateralising and localising motor and language functions. Conclusions: A striking finding of the review is the paucity of studies (n = 34) focusing on the paediatric epilepsy surgery population. For children, it remains unclear which language and memory paradigms produce optimal activation and how these should be quantified in a statistically robust manner. Consensus needs to be achieved for statistical analyses and the uniformity and yield of language, motor and memory paradigms. Larger scale studies are required to produce patient series data which clinicians may refer to interpret results objectively. If functional imaging techniques are to be the viable alternative for pre-surgical mapping of eloquent cortex for children, paradigms and analyses demonstrating concordance with independent measures must be developed

Bishops who live like princes: Bishop Tebartz-van Elst and the challenge of defining corruption

This article contributes to the debate on defining corruption. Rather than attempting to provide a definitive definition, it uses the case of Franz-Peter Tebartz-van Elst, a German bishop from the diocese of Limburg who stepped down in 2014, to illustrate that the disciplines of law, political science, economics, and anthropology all make important contributions to understanding what corruption is and how it should be conceptualized. Seen through these different lenses, the article argues, the case of “Bishop Bling” can be understood in strikingly different ways. This has ramifications not just for the case itself but also for how analysts understand corruption more broadly. Adopting an overtly interdisciplinary approach does not represent a way to “solve” the definitional dilemma, but it can help analysts understand more about corruption’s multiplicity

Springfield College Seminar Abroad, 1965-66

This is a copy of a color copy of a manuscript titled, Springfield Seminar Abroad. The manuscript contains articles, photographs and a song about the 1965-66 Springfield College seminar abroad. This included 20 students that participated in a year-long program in Edinburgh Scotland under Springfield College professor Dr. George E. Rich. Articles included are the April 9, 1965 Springfield Student Article and articles written by Springfield College students, Charles MacMullen, Carole Crocker and Joan Rague about various periods of the trip. In addition there is a story called "A Ferry Tale" and a poem or lyrics called "Ferry Roaders Theme Song."Both print versions have a blank, dark blue cover with a sticker with the title on it. May have been put on by the library so it was decided not to digitize them.; All blank pages were not scanned. This included the backs of pages and the blank pages at the end of the manuscript.

Data Curation Education

Data curation is the active and ongoing management of research data through its lifecycle of interest and usefulness to scholarship, science, and education. The Graduate School of Library and Information Science at the University of Illinois, Urbana-Champaign has developed a new Data Curation Education Program, which is a concentration within its MSLIS. These slides describe the goals, priorities, and curriculum of the program.Institute of Museum and Library Services (IMLS)unpublishednot peer reviewe

An introduction to the proceedings and a synthesis of the 2010 ices symposium on fishery-dependent information

Current problems and issues concerning the collection and use of fishery-dependent information are reviewed and selected papers in the pages following highlight emergent findings in the field. Key issues include relationships between stakeholders, especially fishers and scientists, and how to develop these constructively, the increasing demands on the quality and range of data on fishing activities and exploitation rates needed to promote the ecosystem approach to fishery management, and technological advances that have allowed new approaches and insights