Attitude angle effects on Nimbus-7 Scanning Multichannel Microwave Radiometer radiances and geophysical parameter retrievals

The attitude of the Nimbus-7 spacecraft has varied significantly over its lifetime. A summary of the orbital and long-term behavior of the attitude angles and the effects of attitude variations on Scanning Multichannel Microwave Radiometer (SMMR) brightness temperatures is presented. One of the principal effects of these variations is to change the incident angle at which the SMMR views the Earth's surface. The brightness temperatures depend upon the incident angle sensitivities of both the ocean surface emissivity and the atmospheric path length. Ocean surface emissivity is quite sensitive to incident angle variation near the SMMR incident angle, which is about 50 degrees. This sensitivity was estimated theoretically for a smooth ocean surface and no atmosphere. A 1-degree increase in the angle of incidence produces a 2.9 C increase in the retrieved sea surface temperature and a 5.7 m/sec decrease in retrieved sea surface wind speed. An incident angle correction is applied to the SMMR radiances before using them in the geophysical parameter retrieval algorithms. The corrected retrieval data is compared with data obtained without applying the correction

The Composition of the Master Schedule

Over a period of about four months, the IVS Coordinating Center (IVSCC) each year composes the Master Schedule for the IVS observing program of the next calendar year. The process begins in early July when the IVSCC contacts the IVS Network Stations to request information about available station time as well as holiday and maintenance schedules for the upcoming year. Going through various planning stages and a review process with the IVS Observing Program Committee (OPC), the final version of the Master Schedule is posted by early November. We describe the general steps of the composition and illustrate them with the example of the planning for the Master Schedule of the 2010 observing year

Effects of Corn Oil and Benzyl Acetate on Number and Size of Azaserine-Induced Foci in the Pancreas of LEW and F344 Rats

The response of LEW and F344 strain rats to the pancreatic carcinogen azaserine was compared using the size and number of azaserine-induced acidophilic acinar cell foci and nodules as parameters in a 4-month experiment. A second experiment compared the effect of corn oil intake by gavage and dietary routes on the growth of azaserine-induced pancreatic lesions in LEW rats. A third experiment tested the activity of benzyl acetate in regard to its ability to induce acinar cell foci or to promote the growth of such foci in azaserine-treated rats. The results showed that equivalent doses of azaserine induce two to seven times more foci in LEW than in F344 rats, and that LEW rats have a higher incidence of spontaneous foci than F344 rats. Azaserine-treated LEW rats that were given 5 mL corn oil/kg body weight 5 days per week by gavage developed more acinar cell foci than rats fed a basal diet (chow). Addition of an equivalent amount of corn oil to chow had a similar effect of enhancing the development of foci. Rats of neither strain developed acinar cell foci when benzyl acetate was given by gavage or in the diet nor was there evidence that benzyl acetate has a significant effect on the development of foci in azaserine-treated rats. These studies also demonstrate that the azaserine/rat model of pancreatic carcinogenesis which was developed in LEW rats can be adapted for use with F344 rats

Effects of Corn Oil and Benzyl Acetate on Number and Size of Azaserine-Induced Foci in the Pancreas of LEW and F344 Rats

The response of LEW and F344 strain rats to the pancreatic carcinogen azaserine was compared using the size and number of azaserine-induced acidophilic acinar cell foci and nodules as parameters in a 4-month experiment. A second experiment compared the effect of corn oil intake by gavage and dietary routes on the growth of azaserine-induced pancreatic lesions in LEW rats. A third experiment tested the activity of benzyl acetate in regard to its ability to induce acinar cell foci or to promote the growth of such foci in azaserine-treated rats. The results showed that equivalent doses of azaserine induce two to seven times more foci in LEW than in F344 rats, and that LEW rats have a higher incidence of spontaneous foci than F344 rats. Azaserine-treated LEW rats that were given 5 mL corn oil/kg body weight 5 days per week by gavage developed more acinar cell foci than rats fed a basal diet (chow). Addition of an equivalent amount of corn oil to chow had a similar effect of enhancing the development of foci. Rats of neither strain developed acinar cell foci when benzyl acetate was given by gavage or in the diet nor was there evidence that benzyl acetate has a significant effect on the development of foci in azaserine-treated rats. These studies also demonstrate that the azaserine/rat model of pancreatic carcinogenesis which was developed in LEW rats can be adapted for use with F344 rats

A Geophysical Interpretation of the Secular Displacement and Gravity Rates Observed at Ny-Ålesund, Svalbard in the Arctic— Effects of Post-Glacial Rebound and Present-Day Ice Melting

We have analysed the Ny-Ålesund very long baseline interferometry (VLBI) data over the period 1994 August to 2004 May, and we obtain secular displacement rates relative to a NNR-NUVEL-1A reference frame of and for the north, east and vertical directions, respectively. The corresponding global positioning system (GPS) station displacement rates relative to the same reference frame for the north, east, and vertical directions are at NYA1 and at NALL, where these GPS rates were derived from the ITRF2000 velocity solution of Heflin. From the comparison at 25 globally distributed collocated sites, we found that the difference in uplift rate between VLBI and GPS at Ny-Ålesund is mainly due to a GPS reference frame scale rate error corresponding to 1.6 mm yr−1 in the GPS vertical rates. The uplift rate was estimated to be 5.2 ± 0.3 mm yr−1 from the analysis of the tide gauge data at Ny-Ålesund. Hence the uplift rates obtained from three different kinds of data are very consistent each other. The absolute gravity (AG) measurements at Ny-Ålesund, which were carried out four times (period: 1998–2002) by three different FG5 absolute gravimeters, lead to a decreasing secular rate of . In this analysis, the actual data obtained from a superconducting gravimeter at Ny-Ålesund were used in the corrections for the gravity tide (including the ocean tide effect) and for the air pressure effect. We have estimated three geophysical contributions to examine the observed rates: (1) the effect of the sea-level (SL) change on a timescale of a few decades, (2) the effect of the present-day ice melting (PDIM) in Svalbard and (3) the sensitivity of the computed post-glacial rebound (PGR) effects to different choices of the models of past ice history and Earth\u27s viscosity parameters. Our analysis indicates that the effect of SL change can be neglected as the main source of the discrepancy. On the other hand, the effect of PDIM cannot be ignored in explaining the mutual relation between the observed horizontal and vertical rates and the predicted ones. A large melting rate of the order of −75 cm yr11 (i.e. roughly 1.6 times larger than the mean rate derived from glaciology over Svalbard) would explain the observed uplift but only half of the gravity changes. Our comparison results clearly point out the importance of both the estimation accuracy of the elastic deformations and better observation accuracy to constrain the size of PGR effects in the northwestern Svalbard more tightly

Understanding Urban Demand for Wild Meat in Vietnam: Implications for Conservation Actions

Vietnam is a significant consumer of wildlife, particularly wild meat, in urban restaurant settings. To meet this demand, poaching of wildlife is widespread, threatening regional and international biodiversity. Previous interventions to tackle illegal and potentially unsustainable consumption of wild meat in Vietnam have generally focused on limiting supply. While critical, they have been impeded by a lack of resources, the presence of increasingly organised criminal networks and corruption. Attention is, therefore, turning to the consumer, but a paucity of research investigating consumer demand for wild meat will impede the creation of effective consumer-centred interventions. Here we used a mixed-methods research approach comprising a hypothetical choice modelling survey and qualitative interviews to explore the drivers of wild meat consumption and consumer preferences among residents of Ho Chi Minh City, Vietnam. Our findings indicate that demand for wild meat is heterogeneous and highly context specific. Wild-sourced, rare, and expensive wild meat-types are eaten by those situated towards the top of the societal hierarchy to convey wealth and status and are commonly consumed in lucrative business contexts. Cheaper, legal and farmed substitutes for wild-sourced meats are also consumed, but typically in more casual consumption or social drinking settings. We explore the implications of our results for current conservation interventions in Vietnam that attempt to tackle illegal and potentially unsustainable trade in and consumption of wild meat and detail how our research informs future consumer-centric conservation actions

GRFS and CRFS in alternative donor hematopoietic cell transplantation for pediatric patients with acute leukemia.

We report graft-versus-host disease (GVHD)-free relapse-free survival (GRFS) (a composite end point of survival without grade III-IV acute GVHD [aGVHD], systemic therapy-requiring chronic GVHD [cGVHD], or relapse) and cGVHD-free relapse-free survival (CRFS) among pediatric patients with acute leukemia (n = 1613) who underwent transplantation with 1 antigen-mismatched (7/8) bone marrow (BM; n = 172) or umbilical cord blood (UCB; n = 1441). Multivariate analysis was performed using Cox proportional hazards models. To account for multiple testing, P \u3c .01 for the donor/graft variable was considered statistically significant. Clinical characteristics were similar between UCB and 7/8 BM recipients, because most had acute lymphoblastic leukemia (62%), 64% received total body irradiation-based conditioning, and 60% received anti-thymocyte globulin or alemtuzumab. Methotrexate-based GVHD prophylaxis was more common with 7/8 BM (79%) than with UCB (15%), in which mycophenolate mofetil was commonly used. The univariate estimates of GRFS and CRFS were 22% (95% confidence interval [CI], 16-29) and 27% (95% CI, 20-34), respectively, with 7/8 BM and 33% (95% CI, 31-36) and 38% (95% CI, 35-40), respectively, with UCB (P \u3c .001). In multivariate analysis, 7/8 BM vs UCB had similar GRFS (hazard ratio [HR], 1.12; 95% CI, 0.87-1.45; P = .39), CRFS (HR, 1.06; 95% CI, 0.82-1.38; P = .66), overall survival (HR, 1.07; 95% CI, 0.80-1.44; P = .66), and relapse (HR, 1.44; 95% CI, 1.03-2.02; P = .03). However, the 7/8 BM group had a significantly higher risk for grade III-IV aGVHD (HR, 1.70; 95% CI, 1.16-2.48; P = .006) compared with the UCB group. UCB and 7/8 BM groups had similar outcomes, as measured by GRFS and CRFS. However, given the higher risk for grade III-IV aGVHD, UCB might be preferred for patients lacking matched donors. © 2019 American Society of Hematology. All rights reserved

Communications Biophysics

Contains reports on seven research projects split into three sections.National Institutes of Health (Grant 5 PO1 NS13126)National Institutes of Health (Grant 1 RO1 NS18682)National Institutes of Health (Training Grant 5 T32 NS07047)National Science Foundation (Grant BNS77-16861)National Institutes of Health (Grant 1 F33 NS07202-01)National Institutes of Health (Grant 5 RO1 NS10916)National Institutes of Health (Grant 5 RO1 NS12846)National Institutes of Health (Grant 1 RO1 NS16917)National Institutes of Health (Grant 1 RO1 NS14092-05)National Science Foundation (Grant BNS 77 21751)National Institutes of Health (Grant 5 R01 NS11080)National Institutes of Health (Grant GM-21189