120 research outputs found
Spectroscopic signature of phosphate crystallization in Erbium-doped optical fibre preforms
In rare-earth-doped silica optical fibres, the homogeneous distribution of
amplifying ions and part of their spectroscopic properties are usually improved
by adding selected elements, such as phosphorus or aluminum, as structural
modifier. In erbium ion (Er3+) doped fibres, phosphorus preferentially
coordinates to Er3+ ions to form regular cages around it. However, the
crystalline structures described in literature never gave particular
spectroscopic signature. In this article, we report emission and excitation
spectra of Er3+ in a transparent phosphorus-doped silica fibre preform. The
observed line features observed at room and low temperature are attributed to
ErPO4 crystallites
The Unfulfilled Potential of Data-Driven Decision Making in Agile Software Development
With the general trend towards data-driven decision making (DDDM),
organizations are looking for ways to use DDDM to improve their decisions.
However, few studies have looked into the practitioners view of DDDM, in
particular for agile organizations. In this paper we investigated the
experiences of using DDDM, and how data can improve decision making. An emailed
questionnaire was sent out to 124 industry practitioners in agile software
developing companies, of which 84 answered. The results show that few
practitioners indicated a widespread use of DDDM in their current decision
making practices. The practitioners were more positive to its future use for
higher-level and more general decision making, fairly positive to its use for
requirements elicitation and prioritization decisions, while being less
positive to its future use at the team level. The practitioners do see a lot of
potential for DDDM in an agile context; however, currently unfulfilled
Data-driven elicitation of quality requirements in agile companies
Quality Requirements (QRs) are a key artifact to ensure the quality and success of a software system. Despite its importance, QRs have not reached the same degree of attention as its functional counterparts, especially in the context of trending software development methodologies like Agile Software Development (ASD). Moreover, crucial information that can be obtained from data sources of a project under development (e.g. JIRA, github,…) are not fully exploited, or even neglected, in QR elicitation activities. In this work, we present a data-driven approach to semi-automatically generate and document QRs in the context of ASD. We define an architecture focusing on the process and the artefacts involved. We validate and iterate on such architecture by conducting workshops in four companies of different size and profile. Finally, we present the implementation of such architecture, considering the feedback and outcomes of the conducted workshops.Peer ReviewedPostprint (author's final draft
The unfulfilled potential of data-driven decision making in agile software development
With the general trend towards data-driven decision making (DDDM), organizations are looking for ways to use DDDM to improve their decisions. However, few studies have looked into the practitioners view of DDDM, in particular for agile organizations. In this paper we investigated the experiences of using DDDM, and how data can improve decision making. An emailed questionnaire was sent out to 124 industry practitioners in agile software developing companies, of which 84 answered. The results show that few practitioners indicated a wide-spread use of DDDM in their current decision making practices. The practitioners were more positive to its future use for higher-level and more general decision making, fairly positive to its use for requirements elicitation and prioritization decisions, while being less positive to its future use at the team level. The practitioners do see a lot of potential for DDDM in an agile context; however, currently unfulfilled
Crowd Intelligence in Requirements Engineering: Current Status and Future Directions
Software systems are the joint creative products of multiple stakeholders, including both designers and users, based on their perception, knowledge and personal preferences of the application context. The rapid rise in the use of Internet, mobile and social media applications make it even more possible to provide channels to link a large pool of highly diversified and physically distributed designers and end users, the crowd. Converging the knowledge of designers and end users in requirements engineering process is essential for the success of software systems. In this paper, we report the findings of a survey of the literature on crowd-based requirements engineering research. It helps us understand the current research achievements, the areas of concentration, and how requirements related activities can be enhanced by crowd intelligence. Based on the survey, we propose a general research map and suggest the possible future roles of crowd intelligence in requirements engineering
Flexural Performance of Steel Reinforced ECC-Concrete Composite Beams Subjected to Freeze–Thaw Cycles
YesExperimental and theoretical investigations on the flexural performance of steel reinforced ECC-concrete composite beams subjected to freeze–thaw cycles are presented in this paper. Four groups of reinforced composite beams with different ECC height replacement ratios subject to 0, 50, 100 and 150 cycles of freeze–thaw were physically tested to failure. Experimental results show that the bending capacity decreases with the increase of freeze–thaw cycles regardless of ECC height replacement ratios. However, the ultimate moment, stiffness and durability of ECC specimens and ECC-concrete composite specimens are greater than those of traditional concrete specimens, owing to the excellent tensile performance of ECC materials. With the increase of ECC height, the crack width and average crack spacing gradually decrease. According to materials’ constitutive models, compatibility and equilibrium conditions, three failure modes with two boundary failure conditions are proposed. Simplified formulas for the moment capacity are also developed. The results predicted by the simplified formulas show good agreement with the experimental moment capacity and failure modes. A parametric analysis is conducted to study the influence of strength and height of ECC, amount of reinforcement, concrete strength and cycles of freeze–thaw on moment capacity and curvature ductility of ECC-concrete composite beams
Hereditary breast cancer in Middle Eastern and North African (MENA) populations: identification of novel, recurrent and founder BRCA1 mutations in the Tunisian population
Germ-line mutations in BRCA1 breast cancer susceptibility gene account for a large proportion of hereditary breast cancer families and show considerable ethnic and geographical variations. The contribution of BRCA1 mutations to hereditary breast cancer has not yet been thoroughly investigated in Middle Eastern and North African populations. In this study, 16 Tunisian high-risk breast cancer families were screened for germline mutations in the entire BRCA1 coding region and exon–intron boundaries using direct sequencing. Six families were found to carry BRCA1 mutations with a prevalence of 37.5%. Four different deleterious mutations were detected. Three truncating mutations were previously described: c.798_799delTT (916 delTT), c.3331_3334delCAAG (3450 delCAAG), c.5266dupC (5382 insC) and one splice site mutation which seems to be specific to the Tunisian population: c.212 + 2insG (IVS5 + 2insG). We also identified 15 variants of unknown clinical significance. The c.798_799delTT mutation occurred at an 18% frequency and was shared by three apparently unrelated families. Analyzing five microsatellite markers in and flanking the BRCA1 locus showed a common haplotype associated with this mutation. This suggests that the c.798_799delTT mutation is a Tunisian founder mutation. Our findings indicate that the Tunisian population has a spectrum of prevalent BRCA1 mutations, some of which appear as recurrent and founding mutations
Comparative Study of rK39 Leishmania Antigen for Serodiagnosis of Visceral Leishmaniasis: Systematic Review with Meta-Analysis
Visceral Leishmaniasis (VL) is a neglected tropical disease for which serodiagnostic tests are available, but not yet widely implemented in rural areas. The rK39 recombinant protein is derived from a kinesin-like protein of parasites belonging to the Leishmania donovani complex, and has been used in the last two decades for the serodiagnosis of VL. We present here a systematic review and meta-analysis of studies evaluating serologic assays (rK39 strip-test, rK39 ELISA, Direct Agglutination Test [DAT], Indirect Immunofluorescence test [IFAT] and ELISA with a promastigote antigen preparation [p-ELISA]) to diagnose VL to determine the accuracy of rK39 antigen in comparison to the use of other antigen preparations. Fourteen papers fulfilled the inclusion and exclusion selection criteria. The summarized sensitivity for the rK39-ELISA was 92% followed by IFAT 88% and p-ELISA 87%. The summarized specificity for the three diagnostic tests was 81%, 90%, and 77%. Studies comparing the rK39 strip test with DAT found a similar sensitivity (94%) and specificity (89%). However, the rK39 strip test was more specific than the IFAT and p-ELISA. In conclusion, we found the rK39 protein used either in a strip test or in an ELISA is a good choice for the serodiagnosis of VL
Influence of bloom number and plastifiers on gelatin matrices produced for enzyme immobilization
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