343 research outputs found
A texture of neutrino mass matrix in view of recent neutrino experimental results
In view of recent neutrino experimental results such as SNO, Super-Kamiokande
(SK), CHOOZ and neutrinoless double beta decay , we
consider a texture of neutrino mass matrix which contains three parameters in
order to explain those neutrino experimental results. We have first fitted
parameters in a model independent way with solar and atmospheric neutrino mass
squared differences and solar neutrino mixing angle which satisfy LMA solution.
The maximal value of atmospheric neutrino mixing angle comes out naturally in
the present texture. Most interestingly, fitted parameters of the neutrino mass
matrix considered here also marginally satisfy recent limit on effective
Majorana neutrino mass obtained from neutrinoless double beta decay experiment.
We further demonstrate an explicit model which gives rise to the texture
investigated by considering an gauge group with two
extra real scalar singlets and discrete symmetry. Majorana
neutrino masses are generated through higher dimensional operators at the scale
. We have estimated the scales at which singlets get VEV's and M by
comparing with the best fitted results obtained in the present work.Comment: Journal Ref.: Phys. Rev. D66, 053004 (2002
Low scale gravity as the source of neutrino masses?
We address the question whether low-scale gravity alone can generate the
neutrino mass matrix needed to accommodate the observed phenomenology. In
low-scale gravity the neutrino mass matrix in the flavor basis is characterized
by one parameter (the gravity scale M_X) and by an exact or approximate flavor
blindness (namely, all elements of the mass matrix are of comparable size).
Neutrino masses and mixings are consistent with the observational data for
certain values of the matrix elements, but only when the spectrum of mass is
inverted or degenerate. For the latter type of spectra the parameter M_{ee}
probed in double beta experiments and the mass parameter probed by cosmology
are close to existing upper limits.Comment: 10 pages, 1 figur
The Problem of Large Leptonic Mixing
Unlike in the quark sector where simple permutation symmetries can
generate the general features of quark masses and mixings, we find it
impossible (under conditions of hierarchy for the charged leptons and without
considering the see-saw mechanism or a more elaborate extension of the SM) to
guarantee large leptonic mixing angles with any general symmetry or
transformation of only known particles. If such symmetries exist, they must be
realized in more extended scenarios.Comment: RevTeX, 4 pages, no figure
Probing the seesaw mechanism with neutrino data and leptogenesis
In the framework of the seesaw mechanism with three heavy right-handed
Majorana neutrinos and no Higgs triplets we carry out a systematic study of the
structure of the right-handed neutrino sector. Using the current low-energy
neutrino data as an input and assuming hierarchical Dirac-type neutrino masses
, we calculate the masses and the mixing of the heavy neutrinos.
We confront the inferred properties of these neutrinos with the constraints
coming from the requirement of a successful baryogenesis via leptogenesis. In
the generic case the masses of the right-handed neutrinos are highly
hierarchical: ; the lightest mass is GeV and the generated baryon-to-photon ratio is
much smaller than the observed value. We find the special cases which
correspond to the level crossing points, with maximal mixing between two
quasi-degenerate right-handed neutrinos. Two level crossing conditions are
obtained: (1-2 crossing) and (2-3
crossing), where and are respectively the 11-entry and the
12-subdeterminant of the light neutrino mass matrix in the basis where the
neutrino Yukawa couplings are diagonal. We show that sufficient lepton
asymmetry can be produced only in the 1-2 crossing where GeV, GeV and .Comment: 30 pages, 2 eps figures, JHEP3.cls, typos corrected, note (and
references) added on non-thermal leptogenesi
LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability
BACKGROUND: Alterations in DNA methylation in cancer include global hypomethylation and gene-specific hypermethylation. It is not clear whether these two epigenetic errors are mechanistically linked or occur independently. This study was performed to determine the relationship between DNA hypomethylation, hypermethylation and microsatellite instability in cancer. METHODOLOGY/PRINCIPAL FINDINGS: We examined 61 cancer cell lines and 60 colorectal carcinomas and their adjacent tissues using LINE-1 bisulfite-PCR as a surrogate for global demethylation. Colorectal carcinomas with sporadic microsatellite instability (MSI), most of which are due to a CpG island methylation phenotype (CIMP) and associated MLH1 promoter methylation, showed in average no difference in LINE-1 methylation between normal adjacent and cancer tissues. Interestingly, some tumor samples in this group showed increase in LINE-1 methylation. In contrast, MSI-showed a significant decrease in LINE-1 methylation between normal adjacent and cancer tissues (P<0.001). Microarray analysis of repetitive element methylation confirmed this observation and showed a high degree of variability in hypomethylation between samples. Additionally, unsupervised hierarchical clustering identified a group of highly hypomethylated tumors, composed mostly of tumors without microsatellite instability. We extended LINE-1 analysis to cancer cell lines from different tissues and found that 50/61 were hypomethylated compared to peripheral blood lymphocytes and normal colon mucosa. Interestingly, these cancer cell lines also exhibited a large variation in demethylation, which was tissue-specific and thus unlikely to be resultant from a stochastic process. CONCLUSION/SIGNIFICANCE: Global hypomethylation is partially reversed in cancers with microsatellite instability and also shows high variability in cancer, which may reflect alternative progression pathways in cancer
The Functional Renormalization Group and O(4) scaling
The critical behavior of the chiral quark-meson model is studied within the
Functional Renormalization Group (FRG). We derive the flow equation for the
scale dependent thermodynamic potential at finite temperature and density in
the presence of a symmetry-breaking external field. Within this scheme, the
critical scaling behavior of the order parameter, its transverse and
longitudinal susceptibilities as well as the correlation lengths near the
chiral phase transition are computed. We focus on the scaling properties of
these observables at non-vanishing external field when approaching the critical
point from the symmetric as well as from the broken phase. We confront our
numerical results with the Widom-Griffiths form of the magnetic equation of
state, obtained by a systematic epsilon-expansion of the scaling function. Our
results for the critical exponents are consistent with those recently computed
within Lattice Monte-Carlo studies of the O(4) spin system.Comment: 14 pages, 11 figure
Astronomical Distance Determination in the Space Age: Secondary Distance Indicators
The formal division of the distance indicators into primary and secondary leads to difficulties in description of methods which can actually be used in two ways: with, and without the support of the other methods for scaling. Thus instead of concentrating on the scaling requirement we concentrate on all methods of distance determination to extragalactic sources which are designated, at least formally, to use for individual sources. Among those, the Supernovae Ia is clearly the leader due to its enormous success in determination of the expansion rate of the Universe. However, new methods are rapidly developing, and there is also a progress in more traditional methods. We give a general overview of the methods but we mostly concentrate on the most recent developments in each field, and future expectations. © 2018, The Author(s)
Feasibility studies for the measurement of time-like proton electromagnetic form factors from p¯ p→ μ+μ- at P ¯ ANDA at FAIR
This paper reports on Monte Carlo simulation results for future measurements of the moduli of time-like proton electromagnetic form factors, | GE| and | GM| , using the p¯ p→ μ+μ- reaction at P ¯ ANDA (FAIR). The electromagnetic form factors are fundamental quantities parameterizing the electric and magnetic structure of hadrons. This work estimates the statistical and total accuracy with which the form factors can be measured at P ¯ ANDA , using an analysis of simulated data within the PandaRoot software framework. The most crucial background channel is p¯ p→ π+π-, due to the very similar behavior of muons and pions in the detector. The suppression factors are evaluated for this and all other relevant background channels at different values of antiproton beam momentum. The signal/background separation is based on a multivariate analysis, using the Boosted Decision Trees method. An expected background subtraction is included in this study, based on realistic angular distributions of the background contribution. Systematic uncertainties are considered and the relative total uncertainties of the form factor measurements are presented
Search for Tensor, Vector, and Scalar Polarizations in the Stochastic Gravitational-Wave Background
The detection of gravitational waves with Advanced LIGO and Advanced Virgo has enabled novel tests of general relativity, including direct study of the polarization of gravitational waves. While general relativity allows for only two tensor gravitational-wave polarizations, general metric theories can additionally predict two vector and two scalar polarizations. The polarization of gravitational waves is encoded in the spectral shape of the stochastic gravitational-wave background, formed by the superposition of cosmological and individually unresolved astrophysical sources. Using data recorded by Advanced LIGO during its first observing run, we search for a stochastic background of generically polarized gravitational waves. We find no evidence for a background of any polarization, and place the first direct bounds on the contributions of vector and scalar polarizations to the stochastic background. Under log-uniform priors for the energy in each polarization, we limit the energy densities of tensor, vector, and scalar modes at 95% credibility to Ω0T<5.58×10-8, Ω0V<6.35×10-8, and Ω0S<1.08×10-7 at a reference frequency f0=25 Hz. © 2018 American Physical Society
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society
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