Serum Irisin Levels in Patients with Acute Atrial Fibrillation

Objective: The purpose of this research was to investigate whether changes in serum irisin levels can represent a marker of altered energy requirements in patients with acute atrial fibrillation (AF) undergoing cardioversion (CV). Methods: The research was planned as a randomized, prospective case-control study. Patients presenting to the emergency medicine and cardiology departments of a university hospital due to acute AF were included in the study. Irisin levels were measured from serum specimens collected 24 and 72 hours (h) following restoration of sinus rhythm with CV in patients in AF rhythm. The values obtained were then compared using statistical analysis. Results: Thirty-one patients undergoing CV due to acute AF were enrolled. Mean irisin levels were studied from serum specimens collected 24 and 72 h following restoration of sinus rhythm with CV, and were then compared. No statistically significant difference was determined at comparison of patients’ basal to 24 h, basal to 72 h, and 24 to 72 h mean irisin values (p0.734, p0.958, and p0.643, respectively). Negative correlation was determined between basal serum irisin levels and LDL (r= -0.519, p= 0.002), but no significant correlation was observed with epicardial adipose tissue (EAT) thickness. Conclusion: We determined no change in serum irisin levels studied 24 h and 72 h following return of normal sinus rhythm after CV from basal serum irisin levels in patients with acute AF. No correlation also was determined between serum irisin levels and EAT thickness

User facilitated congestion and attack mitigation

The IEEE Wireless LAN standard has been a true success story by enabling convenient, efficient and low-cost access to broadband networks for both private and professional use. However, the increasing density and uncoordinated operation of wireless access points, combined with constantly growing traffic demands have started hurting the users' quality of experience. On the other hand, the emerging ubiquity of wireless access has placed it at the center of attention for network attacks, which not only raises users' concerns on security but also indirectly affects connection quality due to proactive measures against security attacks. In this work, we introduce an integrated solution to congestion avoidance and attack mitigation problems through cooperation among wireless access points. The proposed solution implements a Partially Observable Markov Decision Process (POMDP) as an intelligent distributed control system. By successfully differentiating resource hampering attacks from overload cases, the control system takes an appropriate action in each detected anomaly case without disturbing the quality of service for end users. The proposed solution is fully implemented on a small-scale testbed, on which we present our observations and demonstrate the effectiveness of the system to detect and alleviate both attack and congestion situations

A RECOVERED PATIENT AFTER MYOCARDIAL INJURY RELATED TO COVID-19; A CASE REPORT

Anjiyotensin dönüştürücü enzim 2 reseptörleri Covid-19'a bağlı miyokard hasarında önemli bir role sahiptir. SARS-CoV-2 virüsünün miyokarda direk toksik etkisi ve enfeksiyona bağlı gelişen miyokardit, sitokin hasarı, mikroanjiyopatik hasar neticesinde miyokard hasarı gelişir ve neticede troponin seviyeleri yükselir. Miyokard hasarına neden olan mekanizmalar; miyokardda hipoksiye neden olan anstabil koroner arter plakları, kalp dokusunda ve koroner arterlerde Anjiyotensin dönüştürücü enzim 2 reseptör upregülasyonu, virüsün miyokard hücrelerine direk toksik etkisi, sistemik inflamasyona bağlı doku hasarı, miyokarda interstisyel fibroz, interferon etkisine bağlı abartılı immün cevap, helper T lenfositlerinden sitokin salınmında artış olarak belirtilebilir. Bu bildirilen vaka, Covid-19 hastalığına bağlı gelişen miyokard hasarını iyileşerek atlatmış, klinik seyri ve gidişatı iyi seyretmiş 47 yaşında erkek bir hastadır. Hasta serviste yatırılarak izlemiştir ve takipte yoğun bakım ihtiyacı gelişmemiştir

Relationship between epicardial fat tissue and left ventricular synchronicity: An observational study

Objective: Left ventricular (LV) systolic synchrony is defined as simultaneous activation of corresponding cardiac segments. Impaired synchrony has some adverse cardiovascular effects, such as LV dysfunction and impaired prognosis. Epicardial fat tissue (EFT) is visceral fat around the heart. Increased EFT thickness is associated with some disorders, such as LV dysfunction and hypertrophy, which play a role in the impairment of LV synchrony. However, the relationship between EFT and LV systolic synchrony has never been assessed. Thus, we aimed to evaluate the possible relationship between EFT and LV synchrony in this study

Relationship between epicardial fat tissue and left ventricular synchronicity: An observational study

Objective: Left ventricular (LV) systolic synchrony is defined as simultaneous activation of corresponding cardiac segments. Impaired synchrony has some adverse cardiovascular effects, such as LV dysfunction and impaired prognosis. Epicardial fat tissue (EFT) is visceral fat around the heart. Increased EFT thickness is associated with some disorders, such as LV dysfunction and hypertrophy, which play a role in the impairment of LV synchrony. However, the relationship between EFT and LV systolic synchrony has never been assessed. Thus, we aimed to evaluate the possible relationship between EFT and LV synchrony in this study

Relationship between epicardial fat tissue and left ventricular synchronicity: An observational study

WOS: 000366597000006PubMed: 25880051Objective: Left ventricular (LV) systolic synchrony is defined as simultaneous activation of corresponding cardiac segments. Impaired synchrony has some adverse cardiovascular effects, such as LV dysfunction and impaired prognosis. Epicardial fat tissue (EFT) is visceral fat around the heart. Increased EFT thickness is associated with some disorders, such as LV dysfunction and hypertrophy, which play a role in the impairment of LV synchrony. However, the relationship between EFT and LV systolic synchrony has never been assessed. Thus, we aimed to evaluate the possible relationship between EFT and LV synchrony in this study. Methods: The study population consisted of 55 consecutive patients (mean age 46.4 +/- 13.4 years, 32 female) without bundle branch block (BBB). EFT and LV systolic synchrony were evaluated by transthoracic echocardiography using 2D and tissue Doppler imaging. Maximal difference (Ts-6) and standard deviation (Ts-SD-6) of time to peak systolic (Ts) myocardial tissue velocity obtained from 6 LV basal segments were used to assess LV synchrony. Multiple regression analysis was used to detect the independently related factors to LV synchrony. Results: The mean values of EFT thickness, Ts-6, and Ts-SD-6 were found to be 2.7 +/- 1.6 mm (ranging from 1-7 mm), 20.1 +/- 14.2 msec, and 7.7 +/- 5.6, respectively. EFT thickness also was independently associated with Ts-6 (beta=0.332, p=0.01) and Ts-SD-6 (beta=0.286, p=0.04). Conclusion: EFT thickness is associated with LV systolic synchrony in patients without BBB