372 research outputs found

    Method And System For Automatically Generating Artificial Intelligence Powered Prototypes

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    The present disclosure relates to a method and a system for automatically generating Artificial Intelligence (AI) powered prototypes. Here, a plurality of AI models is provided in a user interface of the system. Further, a selection of a set of the AI models is received via the user interface. For each of the set of the AI models, identification of input features and data sources is received via the user interface for training each of the plurality of AI models. Further, a selection of one or more rules for aggregating model inputs and model outputs is received via the user interface to form one or more searchable tables of sample data for at least one of the artificial intelligence models. The one or more rules include one or more categories of filtering criteria for populating the one or more searchable tables. In response to the user input, the model inputs in the data sources as defined by the input features are identified and a link between the model inputs and the artificial intelligence model is defined. Further, the one or more searchable tables having one or more columns corresponding to the one or more categories are created. Further, an order of operation of the set of artificial intelligence models is received via the user interface. In the order of operation, an output of one or more first AI models is used as an input for one or more second AI models. Thereafter, an AI ensemble that comprises the set of AI models is generated

    Non-Fermi-liquid d-wave metal phase of strongly interacting electrons

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    Developing a theoretical framework for conducting electronic fluids qualitatively distinct from those described by Landau's Fermi-liquid theory is of central importance to many outstanding problems in condensed matter physics. One such problem is that, above the transition temperature and near optimal doping, high-transition-temperature copper-oxide superconductors exhibit `strange metal' behaviour that is inconsistent with being a traditional Landau Fermi liquid. Indeed, a microscopic theory of a strange-metal quantum phase could shed new light on the interesting low-temperature behaviour in the pseudogap regime and on the d-wave superconductor itself. Here we present a theory for a specific example of a strange metal---the 'd-wave metal'. Using variational wavefunctions, gauge theoretic arguments, and ultimately large-scale density matrix renormalization group calculations, we show that this remarkable quantum phase is the ground state of a reasonable microscopic Hamiltonian---the usual t-J model with electron kinetic energy tt and two-spin exchange JJ supplemented with a frustrated electron `ring-exchange' term, which we here examine extensively on the square lattice two-leg ladder. These findings constitute an explicit theoretical example of a genuine non-Fermi-liquid metal existing as the ground state of a realistic model.Comment: 22 pages, 12 figures: 6 pages, 7 figures of main text + 16 pages, 5 figures of Supplementary Information; this is approximately the version published in Nature, minus various subedits in the main tex

    Diabetes Prevention: Your Role as a Healthcare Professional (July 15, 2020)

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    The Philadelphia Diabetes Prevention Collaborative invites you to learn about the latest in screening, testing and how to easily refer your patients to a National Diabetes Prevention (DPP) lifestyle change program within the greater Philadelphia five-county area. Featuring Health Promotion Council of Southeastern Pennsylvania, the American Medical Association, and the Center for Urban Health and College of Population Health at Jefferso

    Strong-coupling expansion and effective hamiltonians

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    When looking for analytical approaches to treat frustrated quantum magnets, it is often very useful to start from a limit where the ground state is highly degenerate. This chapter discusses several ways of deriving {effective Hamiltonians} around such limits, starting from standard {degenerate perturbation theory} and proceeding to modern approaches more appropriate for the derivation of high-order effective Hamiltonians, such as the perturbative continuous unitary transformations or contractor renormalization. In the course of this exposition, a number of examples taken from the recent literature are discussed, including frustrated ladders and other dimer-based Heisenberg models in a field, as well as the mapping between frustrated Ising models in a transverse field and quantum dimer models.Comment: To appear as a chapter in "Highly Frustrated Magnetism", Eds. C. Lacroix, P. Mendels, F. Mil

    Echocardiography in patients with hypertrophic cardiomyopathy: usefulness of old and new techniques in the diagnosis and pathophysiological assessment

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    Hypertrophic cardiomyopathy (HCM) is one of the most common inherited cardiomyopathy. The identification of patients with HCM is sometimes still a challenge. Moreover, the pathophysiology of the disease is complex because of left ventricular hyper-contractile state, diastolic dysfunction, ischemia and obstruction which can be coexistent in the same patient. In this review, we discuss the current and emerging echocardiographic methodology that can help physicians in the correct diagnostic and pathophysiological assessment of patients with HCM

    HIV Transmission Potential Among Local and Migrant Factory Workers in Kolkata, India

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    Migrant workers in India play a key role in the spread of HIV. Kolkata is a common destination for workers, who may acquire infection and transmit it to their wives and/or other sexual partners. We investigated sexual relations and condom use by factory workers. Migrant and local factory workers were randomly selected from five wards of Kolkata. Information was collected about demographic and socio-economic characteristics, sexual relationships, condom usage, and perceptions and intent to use condoms. Condom use was very low in both groups of workers, particularly among migrants. Many married workers visited female sex workers but never used condoms. Few intended to use condoms, and if they did, it did not always translate into actual usage. There is great potential for transmission of HIV/sexually transmitted infections by these workers. Carefully designed intervention and education programs in the context of low literacy and cultural norms are urgently needed

    Hidden magnetic excitation in the pseudogap phase of a model cuprate superconductor

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    The elucidation of the pseudogap phenomenon of the cuprates, a set of anomalous physical properties below the characteristic temperature T* and above the superconducting transition temperature Tc, has been a major challenge in condensed matter physics for the past two decades. Following initial indications of broken time-reversal symmetry in photoemission experiments, recent polarized neutron diffraction work demonstrated the universal existence of an unusual magnetic order below T*. These findings have the profound implication that the pseudogap regime constitutes a genuine new phase of matter rather than a mere crossover phenomenon. They are furthermore consistent with a particular type of order involving circulating orbital currents, and with the notion that the phase diagram is controlled by a quantum critical point. Here we report inelastic neutron scattering results for HgBa2CuO4+x (Hg1201) that reveal a fundamental collective magnetic mode associated with the unusual order, and that further support this picture. The mode's intensity rises below the same temperature T* and its dispersion is weak, as expected for an Ising-like order parameter. Its energy of 52-56 meV and its enormous integrated spectral weight render it a new candidate for the hitherto unexplained ubiquitous electron-boson coupling features observed in spectroscopic studies.Comment: 8 pages, 3 figures, with supplementary information and figure

    Functional Reconstitution of a Tunable E3-Dependent Sumoylation Pathway in Escherichia coli

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    SUMO (small ubiquitin-related modifier) is a reversible post-translational protein modifier that alters the localization, activity, or stability of proteins to which it is attached. Many enzymes participate in regulated SUMO-conjugation and SUMO-deconjugation pathways. Hundreds of SUMO targets are currently known, with the majority being nuclear proteins. However, the dynamic and reversible nature of this modification and the large number of natively sumoylated proteins in eukaryotic proteomes makes molecular dissection of sumoylation in eukaryotic cells challenging. Here, we have reconstituted a complete mammalian SUMO-conjugation cascade in Escherichia coli cells that involves a functional SUMO E3 ligase, which effectively biases the sumoylation of both native and engineered substrate proteins. Our sumo-engineered E. coli cells have several advantages including efficient protein conjugation and physiologically relevant sumoylation patterns. Overall, this system provides a rapid and controllable platform for studying the enzymology of the entire sumoylation cascade directly in living cells

    A Gapless Hard Wall: Magnetic Catalysis in Bulk and Boundary

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    We study various aspects of fermions and their chiral condensates, both in the bulk of AdS4 spacetime and in the dual boundary theory. For the most part, we focus on a geometry with an infra-red hard wall. We show that, contrary to common lore, there exist boundary conditions in which the hard wall gives rise to a discrete, but gapless, fermionic spectrum. In such a setting, the presence of a magnetic field induces a bulk fermion condensate which spontaneously breaks CP invariance. We develop the holographic dictionary between composite operators and show that this bulk condensate has the interpretation of boundary magnetic catalysis involving a double-trace operator. Finally, we explain how one can replace the hard wall with bulk magnetic monopoles. In such a framework, magnetic catalysis can be viewed as a consequence of the Callan-Rubakov effect.Comment: 43 pages. v2: reference adde
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