4,042 research outputs found

    Notions of symmetry in human movement for recognition

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    Notions of symmetry are powerful for understanding as they explore relationships in nature for analysis. We describe how symmetry analysis can be used to recognize people by their gait. This approachis reinforced by the view from psychology that human gait is a symmetrical pattern of motion and that symmetrical properties of human movement can indeed be used for human gait analysis.Here, we use gait as a vehicle to investigate both the symmetry of moving objects as provided in our new spatial and spatio-temporal symmetry analyses. We apply these symmetry extractions to a numberof databases to demonstrate their potency. A performance analysis shows that using symmetry for gait recognition enjoys practical advantages such as relative immunity to noise, ability to handlemissing information and the capability to handle occlusion. The results show that the symmetrical properties of human gait appear to be unique and can indeed be used for analysis and for recognition with recognition rates exceeding 90%. Best performance is achieved by a spatio-temporal operator, reflecting the view that recognition by gait is not just from body shape, but also by the way the body moves

    Splicing-dependent NMD does not require the EJC in Schizosaccharomyces pombe

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    Nonsense-mediated mRNA decay (NMD) is a translation-linked process that destroys mRNAs with premature translation termination codons (PTCs). In mammalian cells, NMD is also linked to pre-mRNA splicing, usually PTCs trigger strong NMD only when positioned upstream of at least one intron. The exon junction complex (EJC) is believed to mediate the link between splicing and NMD in these systems. Here, we report that in Schizosaccharomyces pombe splicing also enhances NMD, but against the EJC model prediction, an intron stimulated NMD regardless of whether it is positioned upstream or downstream of the PTC and EJC components are not required. Still the effect of splicing seems to be direct—we have found that the important NMD determinant is the proximity of an intron to the PTC, not just the occurrence of splicing. On the basis of these results, we propose a new model to explain how splicing could affect NMD

    Biodiversity in a changing climate: a synthesis of current and projected trends in the US

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    This paper provides a synthesis of the recent literature describing how global biodiversity is being affected by climate change and is projected to respond in the future. Current studies reinforce earlier findings of major climate-change-related impacts on biological systems and document new, more subtle after-effects. For example, many species are shifting their distributions and phenologies at faster rates than were recorded just a few years ago; however, responses are not uniform across species. Shifts have been idiosyncratic and in some cases counterintuitive, promoting new community compositions and altering biotic interactions. Although genetic diversity enhances species\u27 potential to respond to variable conditions, climate change may outpace intrinsic adaptive capacities and increase the relative vulnerabilities of many organisms. Developing effective adaptation strategies for biodiversity conservation will not only require flexible decision-making and management approaches that account for uncertainties in climate projections and ecological responses but will also necessitate coordinated monitoring efforts

    Black Holes in Modified Gravity (MOG)

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    The field equations for Scalar-Tensor-Vector-Gravity (STVG) or modified gravity (MOG) have a static, spherically symmetric black hole solution determined by the mass MM with two horizons. The strength of the gravitational constant is G=GN(1+α)G=G_N(1+\alpha) where α\alpha is a parameter. A regular singularity-free MOG solution is derived using a nonlinear field dynamics for the repulsive gravitational field component and a reasonable physical energy-momentum tensor. The Kruskal-Szekeres completion of the MOG black hole solution is obtained. The Kerr-MOG black hole solution is determined by the mass MM, the parameter α\alpha and the spin angular momentum J=MaJ=Ma. The equations of motion and the stability condition of a test particle orbiting the MOG black hole are derived, and the radius of the black hole photosphere and the shadows cast by the Schwarzschild-MOG and Kerr-MOG black holes are calculated. A traversable wormhole solution is constructed with a throat stabilized by the repulsive component of the gravitational field.Comment: 14 pages, 3 figures. Upgraded version of paper to match published version in European Physics Journal

    PLK4 as a Novel Therapeutic Target in TP53-mutant Acute Myeloid Leukemia

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    https://openworks.mdanderson.org/sumexp23/1059/thumbnail.jp

    Jol-m M . VeiJ..l.cu A

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    I-OSAlamos Abstract RF plasma glow discharges are being investigated for removing and recovering radioactive elements from contaminated objects, especially those contaminated with transuranic (TRU) materials. These plasmas, using nitrogen trifluoride as the working gas, have been successful at removing uranium and plutonium contaminants from test coupons of stainless steel and aluminum surfaces, including small cracks and crevices, and the interior surfaces of relatively hard to reach aluminum pipes. Contaminant removal exceeded 99.9% from simple surfaces and contaminant recovery using cryogenic traps has exceeded 50$Z0. Work continues with the objective of demonstrating that transuranic contaminated waste can be transformed to low level waste (LLW) and to better understand the physics of the interactions between plasma and surface contaminants. This work summarizes the preliminary results from plasma decontamination from the interior of aluminum objects-the nooks and crannies experiments

    Stationary Black Holes: Uniqueness and Beyond

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    The spectrum of known black-hole solutions to the stationary Einstein equations has been steadily increasing, sometimes in unexpected ways. In particular, it has turned out that not all black-hole-equilibrium configurations are characterized by their mass, angular momentum and global charges. Moreover, the high degree of symmetry displayed by vacuum and electro-vacuum black-hole spacetimes ceases to exist in self-gravitating non-linear field theories. This text aims to review some developments in the subject and to discuss them in light of the uniqueness theorem for the Einstein-Maxwell system.Comment: Major update of the original version by Markus Heusler from 1998. Piotr T. Chru\'sciel and Jo\~ao Lopes Costa succeeded to this review's authorship. Significantly restructured and updated all sections; changes are too numerous to be usefully described here. The number of references increased from 186 to 32
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