390 research outputs found

    Norway – 2019

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    IMPACT OF WORKPLACE ENVIRONMENT ON PERFORMANCE IN UNIVERSITY LIBRARIES OF LAHORE, PAKISTAN

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    Goals of this study were to know the effect of library’s work environment for job performance of librarians and existence of any relationship between work environment and job performance of librarians. A quantitative study design was carried out to explore phenomenon through the librarian’s perceptions, delights and choices about their administrative center surroundings. Survey method was used in this study. The target population of this study was Librarians of HEC recognized Public and Private Universities of Lahore City. The structured questionnaire was used for data collection from respondents. There had been a hundred and twenty questionnaires dispensed among librarians, the researcher became succeeded in receiving ninety-six questionnaires from members. The reaction rate was 80 percent. Descriptive statistics were utilized for description of information such as frequencies, mean scores and standard deviation. Regression analysis has been performed to measure the impact of workplace environment on the job performance. Findings of the study show that there is the shortage of calm environment to the employees. Job descriptions are not clearly designed. No proper training opportunities are provided to the workers. Employees are not properly motivated. Findings of the study may prove useful in providing a congenial environment to the employees so that performance may be improved

    Role of Media and Judiciary in Public Policy Making in Pakistan: Evidence from Suo Moto Cases based on Media Reports

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    The role of mass media in policy agenda setting has been considered by an array of researchers. The mass media is not sole factor behind the policy agenda, but it is an important factor among several others. The agenda-setting theory assumes that the media possess the capability to relocate their agenda to the public agenda. Judiciary in Pakistan also seem to be influenced by the agenda-setting function of mass media. The study aims to examine the indirect influence of mass media on public policy by critically analysing the influence of judicial interventions in the form of suo motu on policy making in Pakistan. The time period of the study ranges from 2008 to 2013. The unit of analysis is a single case based on sou motu action taken by the Supreme Court of Pakistan (SCP). All the suo motu actions taken by the SCP based on media reports during the time period have been analysed. The data have been collected from the archives of the SCP and by overviewing the original court files of the cases. The contents analysis reveals that the SCP taken total 90 suo motu cases during the period, and out of these cases, 56 cases were based on media reports. The study further analyses the decisions in these cases influencing the policy making in Pakistan. The findings reveal that 19 court cases based on media reports have influenced the public policy making in Pakistan

    ANALYSIS OF URDU LANGUAGE COLLECTION IN UNIVERSITY LIBRARIES OF LAHORE, PAKISTAN

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    Mother language and national language play pivotal role in the educational developments of the nations. Much importance is being awarded for the promotion of these languages all over the world as well as inPakistan. National languages are considered as official languages in many of the countries. In this regard recently the Government of Pakistan and courts ruled out the implementation of Urdu as official language. Quantitative research method followed by survey was opted for the completion of this study. Two separate questionnaires were used to get the relevant data from the respondents (Librarians and Students). This study explored library collection (including Urdu language collection) which is in total 1299384 books, 497 journals, 76 magazines, 89 newspapers, 34504 thesis/ dissertations/ projects, 13211 audio/ video (CDs/DVDs) and 18000 other types of collections available cumulatively in the public sector university libraries of the Lahore and also explored that majority of public sector libraries in Lahore have collection in Urdu language on various subjects but a very little in numbers. Change of curricula in English medium; lack of enough space in libraries and availability of similar information in other languages are pointed out as major hurdle for acquisition of the material in Urdu language. Regarding users’ perception it was revealed that they consider the books in Urdu language as more useful for the better understanding of concepts. Regarding satisfaction the users it is found they are satisfied with the availability of collection in Urdu language in their university libraries. The majority of respondents read books in Urdu language for leisure reading while books in English language for their course work

    Enhanced regeneration in explants of tomato (Lycopersicon esculentum L.) with the treatment of coconut water

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    A standardized protocol was developed to enhance the in vitro regeneration efficiency of five varieties of tomato from hypocotyls and leaf disc with the involvement of coconut water. Different concentrations of IAA and kinetin were used alone and in combination with 12% of coconut water.Significant differences for regeneration, time taken to regenerate and number of leaf primordial were observed for different treatments, type of explant, use of coconut water and also among varieties. Higher regeneration was obtained in Avinash followed by Roma and Rio Grande. Maximum regeneration 95.75% was obtained with 0.5 mgL-1 of IAA, 1.5 mgL-1 Kinetin along with 12% coconut water in Avinash and hypocotyl was proved to be better for regeneration than leaf discs. The inclusionof coconut water in the media significantly reduced the number of days taken for callus induction leading to regeneration, as compared to media without coconut water. Significant increase in number of shoot primordial was observed in hypocotyls as well as in leaf disc derived calli with the addition of coconut water. Plants obtained were transferred to the glass house in small pots of compost and higher frequency of survival was observed from plantlets obtained with the addition of coconut water

    Identification of an N-terminal 27 kDa fragment of Mycoplasma pneumoniae P116 protein as specific immunogen in M. pneumoniae infections

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    <p>Abstract</p> <p>Background</p> <p><it>Mycoplasma pneumoniae </it>is an important cause of respiratory tract infection and is increasingly being associated with other diseases such as asthma and extra-pulmonary complications. Considerable cross-reactivity is known to exist between the whole cell antigens used in the commercial serological testing assays. Identification of specific antigens is important to eliminate the risk of cross-reactions among different related organisms. Adherence of <it>M. pneumoniae </it>to human epithelial cells is mediated through a well defined apical organelle to which a number of proteins such as P1, P30, P116 and HMW1-3 have been localized, and are being investigated for adhesion, gliding and immunodiagnostic purposes.</p> <p>Methods</p> <p>A 609 bp fragment P116<sub>(N-27), </sub>corresponding to the N-terminal region of <it>M. pneumoniae </it>P116 gene was cloned and expressed. A C-terminal fragment P1<sub>(C-40), </sub>of P1 protein of <it>M. pneumoniae </it>was also expressed. Three IgM ELISA assays based on P116<sub>(N-27), </sub>P1<sub>(C-40) </sub>and (P116 <sub>(N-27) </sub>+ P1<sub>(C-40)</sub>) proteins were optimized and a detailed analysis comparing the reactivity of these proteins with a commercial kit was carried out. Comparative statistical analysis of these assays was performed with the SPSS version 15.0.</p> <p>Results</p> <p>The expressed P116<sub>(N-27) </sub>protein was well recognized by the patient sera and was immunogenic in rabbit. P1<sub>(C-40) </sub>of <it>M. pneumoniae </it>was also immunogenic in rabbit. In comparison to the reference kit, which is reported to be 100% sensitive and 75% specific, ELISA assay based on purified P116<sub>(N-27), </sub>P1<sub>(C-40) </sub>and (P116<sub>(N-27) </sub>+ P1<sub>(C-40)</sub>) proteins showed 90.3%, 87.1% and 96.8% sensitivity and 87.0%, 87.1% and 90.3% specificity respectively. The p value for all the three assays was found to be < 0.001, and there was a good correlation and association between them.</p> <p>Conclusion</p> <p>This study shows that an N-terminal fragment of P116 protein holds a promise for serodiagnosis of <it>M. pneumoniae </it>infection. The IgM ELISA assays based on the recombinant proteins seem to be suitable for the use in serodiagnosis of acute <it>M. pneumoniae </it>infections. The use of short recombinant fragments of P116 and P1 proteins as specific antigens may eliminate the risk of cross-reactions and help to develop a specific and sensitive immunodiagnostic assay for <it>M. pneumoniae </it>detection.</p

    β-Amyloid 25-35 Peptide Reduces the Expression of Glutamine Transporter SAT1 in Cultured Cortical Neurons

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    β-Amyloid (Aβ) peptides may cause malfunction and death of neurons in Alzheimer’s disease. We investigated the effect of Aβ on key transporters of amino acid neurotransmission in cells cultured from rat cerebral cortex. The cultures were treated with Aβ(25-35) at 3 and 10 μM for 12 and 24 h followed by quantitative analysis of immunofluorescence intensity. In mixed neuronal–glial cell cultures (from P1 rats), Aβ reduced the concentration of system A glutamine transporter 1 (SAT1), by up to 50% expressed relative to the neuronal marker microtubule-associated protein 2 (MAP2) in the same cell. No significant effects were detected on vesicular glutamate transporters VGLUT1 or VGLUT2 in neurons, or on glial system N glutamine transporter 1 (SN1). In neuronal cell cultures (from E18 rats), Aβ(25-35) did not reduce SAT1 immunoreactivity, suggesting that the observed effect depends on the presence of astroglia. The results indicate that Aβ may impair neuronal function and transmitter synthesis, and perhaps reduce excitotoxicity, through a reduction in neuronal glutamine uptake

    Mobile health in adults with congenital heart disease: Current use and future needs

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    Objective Many adults with congenital heart disease (CHD) are affected lifelong by cardiac events, particularly arrhythmias and heart failure. Despite the care provided, the cardiac event rate remains high. Mobile health (mHealth) brings opportunities to enhance daily monitoring and hence timely response in an attempt to improve outcome. However, it is not known if adults with CHD are currently using mHealth and what type of mHealth they may need in the near future. Methods Consecutive adult patients with CHD who visited the outpatient clinic at the Academic Medical Center in Amsterdam were asked to fill out questionnaires. Exclusion criteria for this study were mental impairment or inability to read and write Dutch. Results All 118 patients participated (median age 40 (range 18–78) years, 40 % male, 49 % symptomatic) and 92 % owned a smartphone. Whereas only a small minority (14 %) of patients used mHealth, the large majority (75 %) were willing to start. Most patients wanted to use mHealth in order to receive more information on physical health, and advice on progression of symptoms or signs of deterioration. Analyses on age, gender and complexity of defect showed significantly less current smartphone usage at older age, but no difference in interest or preferences in type of mHealth application for the near future. Conclusion The relatively young adult CHD population only rarely uses mHealth, but the majority are motivated to start using mHealth. New mHealth initiatives are required in these patients with a chronic condition who need lifelong surveillance in order to reveal if a reduction in morbidity and mortality and improvement in quality of life can be achieved

    Changes in Seizure Frequency and Test-Retest Scores on the Wechsler Adult Intelligence Scale

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    Test-retest performance on the Wechsler Adult Intelligence Scale (WAIS) of two groups of adult epilepsy patients are presented and compared. In one group, Seizures Improved (SI) group, seizure frequency had decreased during the test-retest interval, and in the other group, Seizures Unimproved (SU) group, the number of seizures had either increased or stayed the same over the test-retest interval. The SI group showed a significant test-retest improvement on WAIS Verbal IQ, Performance 1Q, and Full Scale IQ, as well as on eight of 11 WAIS subtests. In comparison, the SU group showed significant increases only on the Performance IQ and Object Assembly subtest. Furthermore, differences between the two groups were observed in the pattern of test-retest changes seen on the Performance measures relative to the Verbal measures. The results suggest that change in seizure frequency is one of the factors associated with test-retest changes in the intellectual functioning of epilepsy patients. RÉSUMÉ Les rÉsultats obtenus À I‘Échelle de WAIS (Wechsler Adults Intelligence Scale) a partir d'une passation I (test) et d'une passation II (retest) chez deux groupes d'Épileptiques adultes sont prÉsentÉs et compares: (a) Dans un groupe la frequence des crises a diminue dur-ant I'intervalle “test-retest” (c'est a dire dans I'inter-valle separant la passation I (test) de la passation II (retest): Groupe des crises ameliorees (SI: seizures improved), (b) Dans l'autre groupe le nombre des crises au contraire a augmente ou bien est reste iden-tique au cours de I'intervalle “test-retest”: Groupe des crises non ameliorees (SU: seizures unimproved). Le groupe des “crises ameliorees” montre une amelioration significative tant sur le plan du QIV (quotient de I'echelle verbale), que du QIP (quotient de I'echelle performance) et du QIG (quotient global), ainsi que de 8 des subtests parmi les onze que contien I'echelle. En comparaison le groupe des “crises non ameliorees” ne montre une amelioration significative qu'au niveau du QIP et en particulier sur le subtest d'assemblage d'ob-jets (celui-ci faisant partie de I'echelle performance). De plus, on observe entre les deux groupes des differences du “type” des modifications entrainees par la situation “test-retest”, sur les rÉsultats obtenus a I'echelle performance et ceux obtensus a I'echelle verbale. Ces rÉsultats permettent de suggerer que, dans le fonctionnement intellectuel des sujets epileptiques, les changements dans la frequence des crises sont un des facteurs a mettre en correlation avec les changements observes a partir de la situation “test-retest”. RESUMEN Se compararon dos grupos de adultos con epilepsia por medio del rendimiento en dos tests de WAIS. En un grupo, la frecuencia de los ataques habia disminuido en el intervalo entre el primer test y el segundo [grupo con mejoria (SI)], mientras que en el otro el mimero de crisis no habia variado o habia au-mentado [grupo sin mejoria (SU)]. El grupo SI mostro una mejoria en laescala verbal CI, en la realizacion CI, en la escala total de CI y en los subtests WAIS. En comparacion, el grupo SU solo mostro un aumento significativo en la realizacion CI y en el subtest de Reunion de Objetos. Ademas, se observaron diferen-cias entre los dos grupos en lo que respecta a la prim-era y a la segunda prueba en la realizacion de las medidas verbales. Los resultados sugieren que los cambios en la frecuencia de los ataques juegan un papel en lo que respecta a funciÓn intelectual cuando se compara el primer WAIS con el segundo. ZUSAMMENFASSUNG Test und Retest Ergebnisse im WAIS von 2 Gruppen erwachsener Epileptiker werden dargestellt und ver-glichen. In einer Gruppe hatte die Anfallshaufigkeit wahrend des Test-Retest-Intervalls abgenommen– verbesserte Gruppe (SI)–und in einer anderen Gruppe war die Anfallshaufigkeit entweder gestiegen oder gleich geblieben wahrend des Test-Retest-Intervalls– unveranderte Gruppe (SU). Die SI-Gruppe zeigte signifikante Verbesserung zwischen Test und Retest im Verbal-IQ des WAIS, im Handlungsteil und im Gesamt-IQ ebenso wie in 8 von 11 WAIS Subtests. Im Vergleich hierzu zeigte die SU-Gruppe signifikante Verbesserung nur im Handlungs-IQ und im Objekte-zuordnungs-Subtest. Weiterhin wurden Unterschiede zwischen den beiden Gruppen im Muster der Test-Retest-Veranderungen im Verhaltnis des Handlung-steils zum Verbalteil bemerkt. Die Ergebnisse lassen vermuten, dalJ die Veranderung der Anfallshaufigkeit einer der Faktoren ist, der hinsichtlich der in-tellektuellen Funktion anfallskranker Patienten Bezie-hungen zu den Veranderungen des Test-Retest-Ergeb-nis aufweist.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65457/1/j.1528-1157.1981.tb04334.x.pd
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