Spectral variability in Swift and Chandra observations of the Ultraluminous source NGC 55 ULX1

NGC 55 ULX1 is a bright Ultraluminous X-ray source located 1.78 Mpc away. We analysed a sample of 20 Swift observations, taken between 2013 April and August, and two Chandra observations taken in 2001 September and 2004 June. We found only marginal hints of a limited number of dips in the light curve, previously reported to occur in this source, although the uncertainties due to the low counting statistics of the data are large. The Chandra and Swift spectra showed clearly spectral variability which resembles those observed in other ULXs. We can account for this spectral variability in terms of changes in both the normalization and intrinsic column density of a two-components model consisting of a blackbody (for the soft component) and a multicolour accretion disc (for the hard component). We discuss the possibility that strong outflows ejected by the disc are in part responsible for such spectral changes.Comment: 9 pages, 6 figure; accepted to be published on MNRA

Discovery of a 6.4 h black hole binary in NGC 4490

We report on the discovery with Chandra of a strong modulation (~90% pulsed fraction) at ~6.4 h from the source CXOU J123030.3+413853 in the star-forming, low-metallicity spiral galaxy NGC 4490, which is interacting with the irregular companion NGC 4485. This modulation, confirmed also by XMM-Newton observations, is interpreted as the orbital period of a binary system. The spectra from the Chandra and XMM-Newton observations can be described by a power-law model with photon index ~1.5. During these observations, which span from 2000 November to 2008 May, the source showed a long-term luminosity variability by a factor of ~5, between ~2E+38 and 1.1E+39 erg/s (for a distance of 8 Mpc). The maximum X-ray luminosity, exceeding by far the Eddington limit of a neutron star, indicates that the accretor is a black hole. Given the high X-ray luminosity, the short orbital period and the morphology of the orbital light curve, we favour an interpretation of CXOU J123030.3+413853 as a rare high-mass X-ray binary system with a Wolf-Rayet star as a donor, similar to Cyg X-3. This would be the fourth system of this kind known in the local Universe. CXOU J123030.3+413853 can also be considered as a transitional object between high mass X-ray binaries and ultraluminous X-ray sources (ULXs), the study of which may reveal how the properties of persistent black-hole binaries evolve entering the ULX regime.Comment: Fig. 1 in reduced quality; minor changes to match the MNRAS versio

Modeling and simulation of cancer immunoprevention vaccine

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The hydrophobicity modulation of glass and marble materials by different Si-based coatings

Hydrophobic polymers applied on hydroxylated surfaces increase their durability against undesired weathering processes. The achievement of a certain degree of surface hydrophobicity (reducing the water permeation) constitutes one of the main research focuses. Herein, two commercial Si-based resins (e.g. Alpha\uaeSI30 and Bluesil\uaeBP9710), directly applied on both glass and Carrara marble substrates, and a silanization process by using trichloromethylsilane (TCMS) were adopted. Contact angle measurements together with hysteresis determination and Surface Free Energy (SFE) were carried out to evaluate the hydrophobic features. Hence, since only in the case of TCMS a good hydrophobicity was achieved (\uf071 around 150\ub0), two commercial polysiloxane-based additives (e.g. TegoPhobe 1500N and TegoPhobe 1650) were added respectively to Alpha\uaeSI30 and Bluesil\uaeBP9710, according to their chemical compatibility. These auxiliary substances allowed to decrease the wettability features of either glass or marble. Furthermore, since all the investigated coatings could be used as stone materials protective agents, water capillary absorption and vapor permeability tests were performed. Also in this case, TCMS revealed to be the most performing one among the adopted silane-based resins, thanks to the drastic reduction of absorbed water and the decrease of vapor permeability within the threshold value of 50%. Finally, the coatings stability was evaluated by accelerated ageing tests

Cellulose production is coupled to sensing of the pyrimidine biosynthetic pathway via c-di-GMP production by the DgcQ protein of Escherichia coli

Production of cellulose, a stress response-mediated process in enterobacteria, is modulated in Escherichia coli by the activity of the two pyrimidine nucleotide biosynthetic pathways, namely, the de novo biosynthetic pathway and the salvage pathway, which relies on the environmental availability of pyrimidine nitrogenous bases. We had previously reported that prevalence of the salvage over the de novo pathway triggers cellulose production via synthesis of the second messenger c-di-GMP by the DgcQ (YedQ) diguanylate cyclase. In this work, we show that DgcQ enzymatic activity is enhanced by UTP, whilst being inhibited by N-carbamoyl-aspartate, an intermediate of the de novo pathway. Thus, direct allosteric control by these ligands allows full DgcQ activity exclusively in cells actively synthesizing pyrimidine nucleotides via the salvage pathway. Inhibition of DgcQ activity by N-carbamoyl-aspartate appears to be favoured by protein-protein interaction between DgcQ and PyrB, a subunit of aspartate transcarbamylase, which synthesizes N-carbamoyl-aspartate. Our results suggest that availability of pyrimidine bases might be sensed, somehow paradoxically, as an environmental stress by E. coli. We hypothesize that this link might have evolved since stress events, leading to extensive DNA/RNA degradation or lysis of neighbouring cells, can result in increased pyrimidine concentrations and activation of the salvage pathway

Consorciação de feijão-caupi e milho em um agroecossistema manejado sob bases ecológicas na Região de Dourados, Mato Grosso do Sul.

bitstream/item/68469/1/034-Consorciacao.-shaline.pdfPublicado também no Cadernos de Agroecologia, v. 7, n. 2, 2012