Aplicação localizada de herbicidas para controle de alecrim-do-campo (Vernonia nudiflora) em pastagem natural.

Resumo: Para avaliar o controle de alecrim-do-campo (Vernonia nudiflora) com aplicação de herbicidas de contato, foi conduzido durante 353 dias, um experimento com delineamento de parcelas subdivididas, dispostas em blocos ao acaso, com três repetições em um arranjo fatorial (5x3)+1, sendo cinco herbicidas em três doses mais a testemunha. As parcelas corresponderam aos herbicidas, com doses de 1,5; 3,0 e 4,5 L ha-1 de Tordon, Aminol 806, Garlon, Grazon e Plenum. A abundância de V. nudiflora foi avaliada antes da aplicação e 60 e 353 dias após. A aplicação foi feita com ?roçadeira química? tratorizada, consistindo em uma plataforma com bandejas com altura regulável, que entra em contato somente com as plantas alvo. Os herbicidas não diferiram quanto à redução na abundância do alecrim e todos reduziram significativamente mais que a testemunha. Os tratamentos não interferiram na frequência na composição de espécies desejáveis no campo nativo. O uso do aplicador químico é eficaz para o controle, mesmo com baixas concentrações de herbicidas, tendo eficácia na redução do alecrim-do-campo e preservando as espécies desejáveis para a produção animal. [Located herbicide application to control alecrim-do-campo (Vernonia nudiflora) in natural grassland]. Abstract: To evaluate the control of alecrim-do-campo (Vernonia nudiflora) with contact herbicides, an experiment was conducted during 353 days, following a split plot block design, with three replicates in a (5x3)+1 factorial arrangement, being five herbicides in three doses and the control. The plots corresponded to the herbicides, with doses of 1.5, 3.0 and 4.5 L ha-1 of Tordon, Aminol 806, Garlon, Grazon e Plenum. The presence of V. nudiflora was evaluated prior to application and 60 and 353 days after. The application was made using a chemical applicator, which consists of a platform of adjustable height that contacts only the target plant. The herbicides did not differ in reducing the abundance of V. nudiflora and all of them reduced significantly more than the control. The chemical applicator was effective to control alecrim-do-campo, even with low herbicide concentrations, reducing the Vernonia abundance and not being harmful to the native desirable species

Controle de espécies indesejáveis e preservação de leguminosas de campo nativo com aplicação localizada de herbicidas.

Resumo: Para avaliar o efeito da aplicação localizada de herbicidas por contato, em Desmodium incanum, foi conduzido este estudo pelo período de 353 dias. O delineamento experimental foi de parcelas subdivididas, dispostas em blocos ao acaso, com três repetições em um arranjo fatorial [(5x3)+1], sendo cinco herbicidas mais a testemunha e três épocas de avaliação. As parcelas corresponderam aos herbicidas, locados na dose de 1,5 L ha-1 de Tordon, Aminol 806, Garlon, Grazon e Plenum, sendo compostas por oito quadros dispostos sobre uma transecta fixa. Realizou-se um levantamento prévio ao experimento, e dois levantamentos subseqüentes aos 60 e 365 dias apos a aplicação. A planta indesejável mais frequente era Vernonia nudiflora. Para aplicação dos herbicidas utilizou-se uma 'roçadeira química' tratorizada, consistindo em uma plataforma com bandejas com altura regulável, que entra em contato somente com as plantas alvo. O uso do aplicador químico foi eficaz para o controle de espécies indesejáveis além de não interferir na frequência do Desmodium incanum, sendo interessante a limpeza seletiva e preservação da flora nativa. [Weed control and preservation of native legumes species in natural grassland by herbicide localized application] Abstract: To evaluate the effect of localized application of herbicides by contact, in Desmodium incanum, this trial was conducted during a period of 353 days. The experimental design was a split plot arranged in a randomized block design with three replications in a factorial arrangement [(5x3) +1], five herbicides plus the control and three evaluation periods. The plots corresponded to herbicides, doses were locate: 1.5, 3.0 and 4.5 L ha -1 of Tordon, Aminol 806, Garlon, Grazon e Plenum, being composed by 8 tables arranged on a fixed line. Prior to application, was made a survey, another in 60 and 353 days after application. For the herbicides application, was used a chemical applicator, which consists in an adjustable height platform, and it is contact is only with the target plant. The use of chemical applicator was effective for controlling undesirable species besides not interfere on Desmodium incanum frequency besides being interesting for selective cleaning and preservation of the native vegetation

When Time Is Critical, Is Informed Consent Less So? A Discussion of Patient Autonomy in Emergency Neurosurgery

Neurosurgical interventions frequently occur in an emergency setting. In this setting, patients often have impaired consciousness and are unable to directly express their values and wishes regarding their treatment. The limited time available for clinical decision making has great ethical implications, as the informed consent procedure may become compromised. The ethical situation may be further challenged by different views between the patient, family members, and the neurosurgeon; the presence of advance directives; the use of an innovative procedure; or if the procedure is part of a research project. This moral opinion piece presents the implications of time constraints and a lack of patient capacity for autonomous decision making in emergency neurosurgical situations. Potential solutions to these challenges are presented that may help to improve ethical patient management in emergency settings. Emergency neurosurgery challenges the respect of autonomy of the patient. The outcome in most scenarios will rely on the neurosurgeon acting in a professional way to manage each unique situation in an ethically sound manner.Scientific Assessment and Innovation in Neurosurgical Treatment Strategie

Controle de espécies indesejáveis e preservação de leguminosas de campo nativo com aplicação localizada de herbicidas

To evaluate the effect of localized application of herbicides by contact, in Desmodium incanum, this trial was conducted during a period of 353 days. The experimental design was a split plot arranged in a randomized block design with three replications in a factorial arrangement [(5x3) +1], five herbicides plus the control and three evaluation periods. The plots corresponded to herbicides, doses were locate: 1.5, 3.0 and 4.5 L ha -1 of Tordon, Aminol 806, Garlon, Grazon e Plenum, being composed by 8 tables arranged on a fixed line. Prior to application, was made a survey, another in 60 and 353 days after application. For the herbicides application, was used a chemical applicator, which consists in an adjustable height platform, and it is contact is only with the target plant. The use of chemical applicator was effective for controlling undesirable species besides not interfere on Desmodium incanum frequency besides being interesting for selective cleaning and preservation of the native vegetation.Para avaliar o efeito da aplicação localizada de herbicidas por contato, em Desmodium incanum, foi conduzido este estudo pelo período de 353 dias. O delineamento experimental foi de parcelas subdivididas, dispostas em blocos ao acaso, com três repetições em um arranjo fatorial [(5x3)+1], sendo cinco herbicidas mais a testemunha e três épocas de avaliação. As parcelas corresponderam aos herbicidas, locados na dose de 1,5 L ha-1 de Tordon, Aminol 806, Garlon, Grazon e Plenum, sendo compostas por oito quadros dispostos sobre uma transecta fixa. Realizou-se um levantamento prévio ao experimento, e dois levantamentos subseqüentes aos 60 e 365 dias apos a aplicação. A planta indesejável mais frequente era Vernonia nudiflora. Para aplicação dos herbicidas utilizou-se uma “roçadeira química” tratorizada, consistindo em uma plataforma com bandejas com altura regulável, que entra em contato somente com as plantas alvo. O uso do aplicador químico foi eficaz para o controle de espécies indesejáveis além de não interferir na frequência do Desmodium incanum, sendo interessante a limpeza seletiva e preservação da flora nativa

Aplicação localizada de herbicidas para controle de alecrim-do-campo (vernonia nudiflora) em pastagem natural

To evaluate the control of alecrim-do-campo (Vernonia nudiflora) with contact herbicides, an experiment was conducted during 353 days, following a split plot block design, with three replicates in a (5x3)+1 factorial arrangement, being five herbicides in three doses and the control. The plots corresponded to the herbicides, with doses of 1.5, 3.0 and 4.5 L ha-1 of Tordon, Aminol 806, Garlon, Grazon e Plenum. The presence of V. nudiflora was evaluated prior to application and 60 and 353 days after. The application was made using a chemical applicator, which consists of a platform of adjustable height that contacts only the target plant. The herbicides did not differ in reducing the abundance of V. nudiflora and all of them reduced significantly more than the control. The chemical applicator was effective to control alecrim-do-campo, even with low herbicide concentrations, reducing the Vernonia abundance and not being harmful to the native desirable species.Para avaliar o controle de alecrim-do-campo (Vernonia nudiflora) com aplicação de herbicidas de contato, foi conduzido durante 353 dias, um experimento com delineamento de parcelas subdivididas, dispostas em blocos ao acaso, com três repetições em um arranjo fatorial (5x3)+1, sendo cinco herbicidas em três doses mais a testemunha. As parcelas corresponderam aos herbicidas, com doses de 1,5; 3,0 e 4,5 L.ha-1 de Tordon, Aminol 806, Garlon, Grazon e Plenum. A abundância de V. nudiflora foi avaliada antes da aplicação e 60 e 353 dias após. A aplicação foi feita com “roçadeira química” tratorizada, consistindo em uma plataforma com bandejas com altura regulável, que entra em contato somente com as plantas alvo. Os herbicidas não diferiram quanto à redução na abundância do alecrim e todos reduziram significativamente mais que a testemunha. Os tratamentos não interferiram na frequência na composição de espécies desejáveis no campo nativo. O uso do aplicador químico é eficaz para o controle, mesmo com baixas concentrações de herbicidas, tendo eficácia na redução do alecrim-do-campo e preservando as espécies desejáveis para a produção animal

A Mouse Model of Post-Arthroplasty Staphylococcus aureus Joint Infection to Evaluate In Vivo the Efficacy of Antimicrobial Implant Coatings

Post-arthroplasty infections represent a devastating complication of total joint replacement surgery, resulting in multiple reoperations, prolonged antibiotic use, extended disability and worse clinical outcomes. As the number of arthroplasties in the U.S. will exceed 3.8 million surgeries per year by 2030, the number of post-arthroplasty infections is projected to increase to over 266,000 infections annually. The treatment of these infections will exhaust healthcare resources and dramatically increase medical costs.To evaluate novel preventative therapeutic strategies against post-arthroplasty infections, a mouse model was developed in which a bioluminescent Staphylococcus aureus strain was inoculated into a knee joint containing an orthopaedic implant and advanced in vivo imaging was used to measure the bacterial burden in real-time. Mice inoculated with 5x10(3) and 5x10(4) CFUs developed increased bacterial counts with marked swelling of the affected leg, consistent with an acute joint infection. In contrast, mice inoculated with 5x10(2) CFUs developed a low-grade infection, resembling a more chronic infection. Ex vivo bacterial counts highly correlated with in vivo bioluminescence signals and EGFP-neutrophil fluorescence of LysEGFP mice was used to measure the infection-induced inflammation. Furthermore, biofilm formation on the implants was visualized at 7 and 14 postoperative days by variable-pressure scanning electron microscopy (VP-SEM). Using this model, a minocycline/rifampin-impregnated bioresorbable polymer implant coating was effective in reducing the infection, decreasing inflammation and preventing biofilm formation.Taken together, this mouse model may represent an alternative pre-clinical screening tool to evaluate novel in vivo therapeutic strategies before studies in larger animals and in human subjects. Furthermore, the antibiotic-polymer implant coating evaluated in this study was clinically effective, suggesting the potential for this strategy as a therapeutic intervention to combat post-arthroplasty infections

Increasing risk of revision due to deep infection after hip arthroplasty: A study on 97,344 primary total hip replacements in the Norwegian Arthroplasty Register from 1987 to 2007

Background and purpose Over the decades, improvements in surgery and perioperative routines have reduced the incidence of deep infections after total hip arthroplasty (THA). There is, however, some evidence to suggest that the incidence of infection is increasing again. We assessed the risk of revision due to deep infection for primary THAs reported to the Norwegian Arthroplasty Register (NAR) over the period 1987–2007