Horocyclic harmonic Bergman spaces on homogeneous trees

The main focus of this contribution is on the harmonic Bergman spaces $\mathcal{B}_{\alpha}^{p}$ on the $q$-homogeneous tree $\mathfrak{X}_q$ endowed with a family of measures $\sigma_\alpha$ that are constant on the horocycles tangent to a fixed boundary point and turn out to be doubling with respect to the corresponding horocyclic Gromov distance. A central role is played by the reproducing kernel Hilbert space $\mathcal{B}_{\alpha}^{2}$ for which we find a natural orthonormal basis and formulae for the kernel. We also consider the atomic Hardy space and the bounded mean oscillation space. Appealing to an adaptation of Calder\'on-Zygmund theory and to standard boundedness results for integral operators on $L^p_\alpha$ spaces with H\"ormander-type kernels, we determine the boundedness properties of the Bergman projection

Introducing Life Cycle Assessment in costs and benefits analysis of vegetation management in drainage canals of lowland agricultural landscapes

Nitrogen overload could provoke several effects on water quality in freshwater and coastal environment, in terms of eutrophication and groundwater nitrate contamination. Those effects can have a severe impact on ecosystem function and human health. In order to reduce nitrogen excess, constructed wetlands are usually recognized as a solution, but in recent years interest has been raised on the role of ditches and canals network in efficient nitrogen abatement. In this study, we investigated the environmental and economical sustainability of natural nitrogen removal capacity of both canals vegetation and microbial communities in the Burana-Volano-Navigabile (BVN) basin, located in the Po valley, the largest Italian hydrographic system. Based on life cycle assessment (LCA) approach and cost-benefits analysis, the effectiveness of two different vegetation management scenarios, which differ for the mowing management, on N abatement in the canal network of the case-study area has been compared. The results highlighted that postponing the mowing of aquatic vegetation to the end of vegetative season would contribute to buffer about 90% of the N load conveyed by the canal network during the irrigation period and would reduce of an order of magnitude the potential costs due to environmental damages

Changes in hippocampal Arc protein expression and synaptic plasticity by the presentation of contextual cues linked to drug experience

Contextual cues linked to drug experience have been frequently associated to craving and relapse, with this phenomenon being described in human and experimental animals. Hippocampal synaptic plasticity has been related to learning, memory, and adaptive processes developed during chronic administration of drug abuse. In this study, we investigated if the environmental context associated with withdrawal experience was able to evoke the same behavioral alteration observed after chronic benzodiazepine administration. Furthermore, we studied the hippocampal synaptic plasticity and anatomical expression of Arc protein during withdrawal and the re-exposure to the context associated with anxiety expression (characteristic sign of benzodiazepines withdrawal). It was demonstrated that re-exposure evoked on days 15 and 25 after the first exposure the same behavior. An increased hippocampal synaptic plasticity, expressed as a lower threshold to induce long-term potentiation on dentate gyrus, was observed in animals dependent on diazepam and during retrieval, in the same group, until day 15. This plastic change disappeared 25 days after the first exposure. An overexpression of Arc protein in the dorsal dentate gyrus and CA1 on the first day of withdrawal in the dependent animals was observed.Fil: Monti, María Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Farmacología Experimental de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Farmacología Experimental de Córdoba; ArgentinaFil: Almiron, Romina Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Farmacología Experimental de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Farmacología Experimental de Córdoba; ArgentinaFil: Bignante, Elena Anahi. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Ramirez, Oscar Angel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Farmacología Experimental de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Farmacología Experimental de Córdoba; Argentin

Phase Transformation Modeling of Medium-Carbon Forging Steel

THERMEC 2006The kinetics of phase transformations in medium-carbon forging steels (MCFS) have been modeled based on CALPHAD multicomponent thermodynamics and the classical nucleation-growth theory. New treatments include the time dependency of parabolic growth rate of proeutectoid ferrite (α) , which account for the soft impingement effect by carbon enrichment in austenite (γ). And a potential transition of γ/α interface equilibrium has also been considered depending on temperatures and velocity of the moving interface. To make a realistic prediction of the onset of pearlite (P) transformation, a normal distribution of γ grain size has been assumed and successive α→P transformation kinetics in each grain size have been summated. The developed program coupled with thermodynamic solver, 'ThermoCalc', calculated the isothermal kinetics of MCFS and has been found to predict well the effect of minor difference of chemical composition / holding temperaturesPeer reviewe

Biological activity of enantiomeric complexes [PtCl2L2](L2 is aromatic bisphosphanes and aromatic diamines)

Enantiomeric complexes of formula [PtCl(2)L(2)] [L(2) is (R)-(+)-BINAP and (S)-(-)-BINAP, where BINAP is 2,2'-bis(diphenylphosphane)-1,1'-binaphthyl, and (R)-(+)-DABN and (S)-(-)-DABN, where DABN is 1,1'-binaphthyl-2,2'-diamine], were tested for their cytotoxic activity against three cancer cell lines and for their ability to bind to the human telomeric sequence folded in the G-quadruplex structure. Similar experiments were carried out on prototypal complexes cisplatin and cis-[PtCl(2)(PPh(3))(2)] for comparison. Platinum complexes containing phosphanes proved less cytotoxic to cancer cell lines and less likely to interact with the nucleobases of the G-quadruplex than those containing amines; in both cases the S-(-) isomer was more active than the R-(+) counterpart. More specifically, whereas all the platinum complexes were able to platinate the G-quadruplex structure from the human telomeric repeat, the extent and sites of platination depended on the nature of the ligands. Complexes containing (bulky) phosphanes interacted only with the adenines of the loops, whereas those containing the less sterically demanding amines interacted with adenines and some guanines of the G-quartet

Human protein C concentrate in pediatric septic patients

Severe sepsis and septic shock are leading causes of morbidity and mortality in the pediatric population. Unlike what is suggested for the adult population, recombinant human activated protein C (rhAPC) is contraindicated in children. Long before rhAPC was considered for use in pediatric patients, case reports appeared on the safe administration of protein C zymogen. Therefore, we conducted a systemic review of currently available data on protein C zymogen (PC) use among children affected by severe sepsis or septic shock. A total number of 13 case series or case reports and a dose-finding study were found on the use of PC in the pediatric intensive care unit, reporting on 118 treated children, with an overall survival of 84%. There was no bleeding complication, the only reported complication being a single mild allergic reaction. These studies show that PC is safe, not associated with bleeding and possibly useful for improving coagulation abnormalities of sepsis

Human protein C concentrate in pediatric septic patients

Severe sepsis and septic shock are leading causes of morbidity and mortality in the pediatric population. Unlike what is suggested for the adult population, recombinant human activated protein C (rhAPC) is contraindicated in children. Long before rhAPC was considered for use in pediatric patients, case reports appeared on the safe administration of protein C zymogen. Therefore, we conducted a systemic review of currently available data on protein C zymogen (PC) use among children affected by severe sepsis or septic shock. A total number of 13 case series or case reports and a dose-finding study were found on the use of PC in the pediatric intensive care unit, reporting on 118 treated children, with an overall survival of 84%. There was no bleeding complication, the only reported complication being a single mild allergic reaction. These studies show that PC is safe, not associated with bleeding and possibly useful for improving coagulation abnormalities of sepsis

An ensemble approach of recurrent neural networks using pre-trained embeddings for playlist completion

This paper describes the approach of the D2KLab team to the RecSys Challenge 2018 that focuses on the task of playlist completion. We propose an ensemble strategy of different recurrent neural networks leveraging pre-trained embeddings representing tracks, artists, albums, and titles as inputs. We also use lyrics from which we extract semantic and stylistic features that we fed into the network for the creative track. The RNN learns a probabilistic model from the sequences of items in the playlist, which is then used to predict the most likely tracks to be added to the playlist. Concerning the playlists without tracks, we implemented a fall-back strategy called Title2Rec that generates recommendations using only the playlist title. We optimized the RNN, Title2Rec, and the ensemble approach on a validation set, tuning hyper-parameters such as the optimizer algorithm, the learning rate, and the generation strategy. This approach is effective in predicting tracks for a playlist and flexible to include diverse types of inputs, but it is also computationally demanding in the training phase

Foxa4 favours notochord formation by inhibiting contiguous mesodermal fates and restricts anterior neural development in Xenopus embryos

In vertebrates, the embryonic dorsal midline is a crucial signalling centre that patterns the surrounding tissues during development. Members of the FoxA subfamily of transcription factors are expressed in the structures that compose this centre. Foxa2 is essential for dorsal midline development in mammals, since knock-out mouse embryos lack a definitive node, notochord and floor plate. The related gene foxA4 is only present in amphibians. Expression begins in the blastula –chordin and –noggin expressing centre (BCNE) and is later restricted to the dorsal midline derivatives of the Spemann's organiser. It was suggested that the early functions of mammalian foxa2 are carried out by foxA4 in frogs, but functional experiments were needed to test this hypothesis. Here, we show that some important dorsal midline functions of mammalian foxa2 are exerted by foxA4 in Xenopus. We provide new evidence that the latter prevents the respecification of dorsal midline precursors towards contiguous fates, inhibiting prechordal and paraxial mesoderm development in favour of the notochord. In addition, we show that foxA4 is required for the correct regionalisation and maintenance of the central nervous system. FoxA4 participates in constraining the prospective rostral forebrain territory during neural specification and is necessary for the correct segregation of the most anterior ectodermal derivatives, such as the cement gland and the pituitary anlagen. Moreover, the early expression of foxA4 in the BCNE (which contains precursors of the whole forebrain and most of the midbrain and hindbrain) is directly required to restrict anterior neural development.Fil: Murgan, Sabrina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Castro Colabianchi, Aitana Manuela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Monti, Renato José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Boyadjián López, Laura Elena. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencias; ArgentinaFil: Aguirre, Cecilia Elena. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Gonzalez Stivala, Ernesto. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Carrasco, Andres Eduardo. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; ArgentinaFil: Lopez, Silvia Liliana. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay. Instituto de Biología Celular y Neurociencia "Prof. Eduardo de Robertis". Universidad de Buenos Aires. Facultad de Medicina. Instituto de Biología Celular y Neurociencia; Argentin

Camelina and Pea Intercropping For Weed Control In Organic Farming

A weed management strategy in the organic farming consists in increasing the competitiveness of the cultivated system. Intercropping can improve competitiveness thanks of the better use of resources by reducing their availability for weeds. Camelina (Camelina Sativa L. Crantz) is a promising oilseed crop with low input requirements. Its early vigorous growth could compensate for the low vegetative growth of peas, thus reducing weed emergence. A preliminary study was carried to assess the effect of camelina intercropped with pea on soil coverage and weed incidence in organic farming compared with pea sole-cropping. After 98 days after sowing (DAS), soil coverage significantly differed among treatments, showing the highest values in the intercropping and in sole camelina. The lowest weed density was in the intercropping. The weed control efficiency of intercrops increased by 56% and 23% compared to sole pea and sole camelina, respectively. In conclusio,n camelina-pea intercropping resulted in an interesting herbicide-free alternative crop management enabling to increase soil coverage while reducing weeds