Neighbour coverage: a dynamic probabilistic route discovery for mobile ad hoc networks

Blind flooding is extensively use in ad hoc routing protocols for on-demand route discovery, where a mobile node blindly rebroadcasts received route request (RREQ) packets until a route to a particular destination is established. This can potentially lead to high channel contention, causing redundant retransmissions and thus excessive packet collisions in the network. Such a phenomenon induces what is known as broadcast storm problem, which has been shown to greatly increase the network communication overhead and end-to-end delay. In this paper, we show that the deleterious impact of such a problem can be reduced if measures are taken during the dissemination of RREQ packets. We propose a generic probabilistic method for route discovery, that is simple to implement and can significantly reduce the overhead associated with the dissemination of RREQs. Our analysis reveals that equipping AODV with probabilistic route discovery can result in significant reduction of routing control overhead while achieving good throughput

Nanotoxicity of polyelectrolyte-functionalized titania nanoparticles towards microalgae and yeast: Role of the particle concentration, size and surface charge

We studied the nanotoxicity of titania nanoparticles (TiO₂NPs) of various hydrodynamic diameters and crystallite sizes towards C. reinhardtii microalgae and S. cerevisiae (yeast) upon illumination with UV and visible light. The cell viability was assessed for a range of nanoparticle concentrations and incubation times. We found that bare TiO₂NPs affect the C. reinhardtii cell viability at much lower particle concentrations than for yeast. We observed an increase of the TiO₂NPs toxicity upon illumination with UV light compared with that in dark conditions due to the oxidative stress of the produced reactive oxygen species. We also found an increased TiO₂NPs nanotoxicity upon illumination with visible light which indicates that they may also interfere with the microalgae's photosynthetic system leading to decreased chlorophyll content upon exposure to TiO₂NPs. The results indicate that the larger the hydrodynamic diameter of the TiO₂NPs the lower is their nanotoxicity, with anatase TiO₂NPs generally being more toxic than rutile TiO₂NPs. We also prepared a range of polyelectrolyte-coated TiO₂NPs using a layer by-layer method and studied their nanotoxicity towards yeast and microalgae. We found that the toxicity of the coated TiO₂NPs changes with their surface charge. TiO₂NPs coated with cationic polyelectrolyte as an outer layer exhibit much higher nanotoxicity than the ones with an outer layer of anionic polyelectrolyte. TEM images of sectioned microalgae and yeast cells exposed to different polyelectrolyte-coated TiO₂NPs confirmed the formation of a significant build-up of nanoparticles on the cell surface for bare and cationic polyelectrolyte-coated TiO₂NPs. The effect comes from the increased adhesion of cationic nanoparticles to the cell walls. Significantly, coating the TiO₂NPs with anionic polyelectrolyte as an outer layer led to a reduced adhesion and much lower nanotoxicity due to electrostatic repulsion with the cell walls. This suggest a new way of making cationic TiO₂NPs safer for use in different formulations by pre-coating them with anionic polyelectrolytes. The results of this study give important insights into the various factors controlling the nanotoxicity of TiO₂NPs

Study the Occurrence of Aflatoxins in some Crops and Dry Fruits in Iraqi Markets

This study was conducted to determine the fungal species and aflatoxin contaminations in crops and dried fruits samples from Iraqi markets after collected at one kilogram with 15 replicates from each of wheat, barley, corn, rice, peanut, figs, apricot and raisin in polyethylene packages. Samples were prepared by grinding and cultured on optimum medium for culturing of contamination molds, and extracted the samples to detect the aflatoxins present by used the HPLC system. The results were indicated that’s all collected samples from the crops or dried fruits were contamination with mold species at different levels of counts from log 2.46 to 5.67 CFU/g at each wheat and peanut samples respectively. The results also indicated that Aspergillus niger, A.flavus, A. paraciticus and Fusarium oxysporium. was  a dominant mold when compared with the other molds species. Aflatoxins analysis was showed as aflatoxin B1 only in concentrations ranges between 22.0-93.7ηg/g in dried apricot samples to 161.0-782.0 ng/g in peanut samples, and were not detected the other aflatoxin types in all collected samples. Keywords: Aflatoxins; Crops; Dry Fruits; Iraqi Markets

Towards a Realization of the Condensed-Matter/Gravity Correspondence in String Theory via Consistent Abelian Truncation

We present an embedding of the 3-dimensional relativistic Landau-Ginzburg model for condensed matter systems in an $\mathcal{N}=6$, $U(N)\times U(N)$ Chern-Simons-matter theory (the ABJM model) by consistently truncating the latter to an abelian effective field theory encoding the collective dynamics of ${\cal O}(N)$ of the ${\cal O}(N^2)$ modes. In fact, depending on the VEV on one of the ABJM scalars, a mass deformation parameter $\mu$ and the Chern-Simons level number $k$, our abelianization prescription allows us to interpolate between the abelian Higgs model with its usual multi-vortex solutions and a $\phi^4$ theory. We sketch a simple condensed matter model that reproduces all the salient features of the abelianization. In this context, the abelianization can be interpreted as giving a dimensional reduction from four dimensions.Comment: 4 pages, revtex; reference added, typo corrected; added clarifying paragraphs at end of introduction and on pages 3-4. Version accepted to PR

A Survey on the Project in title

In this paper we present a survey of work that has been done in the project ldquo;Unsupervised Adaptive P300 BCI in the framework of chaotic theory and stochastic theoryrdquo;we summarised the following papers, (Mohammed J Alhaddad amp; 2011), (Mohammed J. Alhaddad amp; Kamel M, 2012), (Mohammed J Alhaddad, Kamel, amp; Al-Otaibi, 2013), (Mohammed J Alhaddad, Kamel, amp; Bakheet, 2013), (Mohammed J Alhaddad, Kamel, amp; Al-Otaibi, 2014), (Mohammed J Alhaddad, Kamel, amp; Bakheet, 2014), (Mohammed J Alhaddad, Kamel, amp; Kadah, 2014), (Mohammed J Alhaddad, Kamel, Makary, Hargas, amp; Kadah, 2014), (Mohammed J Alhaddad, Mohammed, Kamel, amp; Hagras, 2015).We developed a new pre-processing method for denoising P300-based brain-computer interface data that allows better performance with lower number of channels and blocks. The new denoising technique is based on a modified version of the spectral subtraction denoising and works on each temporal signal channel independently thus offering seamless integration with existing pre-processing and allowing low channel counts to be used. We also developed a novel approach for brain-computer interface data that requires no prior training. The proposed approach is based on interval type-2 fuzzy logic based classifier which is able to handle the usersrsquo; uncertainties to produce better prediction accuracies than other competing classifiers such as BLDA or RFLDA. In addition, the generated type-2 fuzzy classifier is learnt from data via genetic algorithms to produce a small number of rules with a rule length of only one antecedent to maximize the transparency and interpretability for the normal clinician. We also employ a feature selection system based on an ensemble neural networks recursive feature selection which is able to find the effective time instances within the effective sensors in relation to given P300 event. The basic principle of this new class of techniques is that the trial with true activation signal within each block has to be different from the rest of the trials within that block. Hence, a measure that is sensitive to this dissimilarity can be used to make a decision based on a single block without any prior training. The new methods were verified using various experiments which were performed on standard data sets and using real-data sets obtained from real subjects experiments performed in the BCI lab in King Abdulaziz University. The results were compared to the classification results of the same data using previous methods. Enhanced performance in different experiments as quantitatively assessed using classification block accuracy as well as bit rate estimates was confirmed. It will be shown that the produced type-2 fuzzy logic based classifier will learn simple rules which are easy to understand explaining the events in question. In addition, the produced type-2 fuzzy logic classifier will be able to give better accuracies when compared to BLDA or RFLDA on various human subjects on the standard and real-world data sets

Predicting the minimum liquid surface tension activity of pseudomonads expressing biosurfactants

Bacteria produce a variety of biosurfactants capable of significantly reducing liquid (aqueous) surface tension (γ) with a range of biological roles and biotechnological uses. In order to determine the lowest achievable surface tension (γMin), we tested a diverse collection of Pseudomonas-like isolates from contaminated soil and activated sludge, and identified those expressing biosurfactants by drop-collapse assay. Liquid surface tension reducing ability was quantitatively determined by tensiometry, with 57 isolates found to significantly lower culture supernatant surface tensions to 24.5 – 49.1 mN m−1. Differences in biosurfactant behaviour determined by foaming, emulsion and oil-displacement assays, was also observed amongst isolates producing surface tensions of 25 – 27 mN m−1, suggesting that a range of structurally-diverse biosurfactants were being expressed. Individual distribution identification (IDI) analysis was used to identify the theoretical probability distribution that best fitted the surface tension data, which predicted a γMin of 24.24 mN m−1. This was in agreement with predictions based on earlier work of published mixed–bacterial spp. data, suggesting a fundamental limit to the ability of bacterial biosurfactants to reduce surface tensions in aqueous systems. This implies a biological restriction on the synthesis and export of these agents or a physical-chemical restriction on their functioning once produced

Direct to consumer advertising via the Internet, a study of hip resurfacing

With increased use of the internet for health information and direct to consumer advertising from medical companies, there is a concern about the quality of the information available for patients. The aim of this study was to examine the quality of health information on the internet for hip resurfacing. An assessment tool was designed to measure quality of information. Websites were measured on credibility of source; usability; currentness of the information; content relevance; content accuracy/completeness and disclosure/bias. Each website assessed was given a total score, based on number of scores achieved from the above categories websites were further analysed on author, geographical origin and possession of an independent credibility check. There was positive correlation between the overall score for the website and the score of each website in each assessment category. Websites by implant companies, doctors and hospitals scored poorly. Websites with an independent credibility check such as Health on the Net (HoN) scored twice the total scores of websites without. Like other internet health websites, the quality of information on hip resurfacing websites is variable. This study highlights methods by which to assess the quality of health information on the internet and advocates that patients should look for a statement of an "independent credibility check" when searching for information on hip resurfacing

Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V).

Arginine vasopressin (AVP) is released from the posterior pituitary and controls water homeostasis. AVP binding to vasopressin V2 receptors (V2Rs) located on kidney collecting duct epithelial cells triggers activation of Gs proteins, leading to increased cAMP levels, trafficking of aquaporin-2 water channels, and consequent increased water permeability and antidiuresis. Typically, loss-of-function V2R mutations cause nephrogenic diabetes insipidus (NDI), whereas gain-of-function mutations cause nephrogenic syndrome of inappropriate antidiuresis (NSIAD). Here we provide further characterization of two mutant V2Rs, R181C and M311V, reported to cause complete and partial NDI respectively, together with a V266A variant, in a patient diagnosed with NSIAD. Our data in HEK293FT cells revealed that for cAMP accumulation, AVP was about 500- or 30-fold less potent at the R181C and M311V mutants than at the wild-type receptor respectively (and about 4000- and 60-fold in COS7 cells respectively). However, in contrast to wild type V2R, the R181C mutant failed to increase inositol phosphate production, while with the M311V mutant, AVP exhibited only partial agonism in addition to a 37-fold potency decrease. Similar responses were detected in a BRET assay for β-arrestin recruitment, with the R181C receptor unresponsive to AVP, and partial agonism with a 23-fold decrease in potency observed with M311V in both HEK293FT and COS7 cells. Notably, the V266A V2R appeared functionally identical to the wild-type receptor in all assays tested, including cAMP and inositol phosphate accumulation, β-arrestin interaction, and in a BRET assay of receptor ubiquitination. Each receptor was expressed at comparable levels. Hence, the M311V V2R retains greater activity than the R181C mutant, consistent with the milder phenotype of NDI associated with this mutant. Notably, the R181C mutant appears to be a Gs protein-biased receptor incapable of signaling to inositol phosphate or recruiting β-arrestin. The etiology of NSIAD in the patient with V266A V2R remains unknown

Complete Sequences of Organelle Genomes from the Medicinal Plant Rhazya Stricta (Apocynaceae) and Contrasting Patterns of Mitochondrial Genome Evolution Across Asterids

Rhazya stricta is native to arid regions in South Asia and the Middle East and is used extensively in folk medicine to treat a wide range of diseases. In addition to generating genomic resources for this medicinally important plant, analyses of the complete plastid and mitochondrial genomes and a nuclear transcriptome from Rhazya provide insights into inter-compartmental transfers between genomes and the patterns of evolution among eight asterid mitochondrial genomes. Results: The 154,841 bp plastid genome is highly conserved with gene content and order identical to the ancestral organization of angiosperms. The 548,608 bp mitochondrial genome exhibits a number of phenomena including the presence of recombinogenic repeats that generate a multipartite organization, transferred DNA from the plastid and nuclear genomes, and bidirectional DNA transfers between the mitochondrion and the nucleus. The mitochondrial genes sdh3 and rps14 have been transferred to the nucleus and have acquired targeting presequences. In the case of rps14, two copies are present in the nucleus; only one has a mitochondrial targeting presequence and may be functional. Phylogenetic analyses of both nuclear and mitochondrial copies of rps14 across angiosperms suggests Rhazya has experienced a single transfer of this gene to the nucleus, followed by a duplication event. Furthermore, the phylogenetic distribution of gene losses and the high level of sequence divergence in targeting presequences suggest multiple, independent transfers of both sdh3 and rps14 across asterids. Comparative analyses of mitochondrial genomes of eight sequenced asterids indicates a complicated evolutionary history in this large angiosperm clade with considerable diversity in genome organization and size, repeat, gene and intron content, and amount of foreign DNA from the plastid and nuclear genomes. Conclusions: Organelle genomes of Rhazya stricta provide valuable information for improving the understanding of mitochondrial genome evolution among angiosperms. The genomic data have enabled a rigorous examination of the gene transfer events. Rhazya is unique among the eight sequenced asterids in the types of events that have shaped the evolution of its mitochondrial genome. Furthermore, the organelle genomes of R. stricta provide valuable genomic resources for utilizing this important medicinal plant in biotechnology applications.King Abdulaziz UniversityIntegrative Biolog