62 research outputs found
Global long terminal repeat activation participates in establishing the unique gene expression programme of classical Hodgkin lymphoma
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 13/12/2018
- Field of study
Long terminal repeat (LTR) elements are wide-spread in the human genome and have the potential to act as promoters and enhancers. Their expression is therefore under tight epigenetic control. We previously reported in classical Hodgkin Lymphoma (cHL) that a member of the THE1B class of LTR elements acted as a promoter for the proto-oncogene and growth factor receptor gene CSF1R and that expression of this gene is required for cHL tumour survival. However, to which extent and how such elements participate in globally shaping the unique cHL gene expression programme is unknown. To address this question we mapped the genome-wide activation of THE1-LTRs in cHL cells using a targeted next generation sequencing approach (RACE-Seq). Integration of these data with global gene expression data from cHL and control B cell lines showed a unique pattern of LTR activation impacting on gene expression, including genes associated with the cHL phenotype. We also show that global LTR activation is induced by strong inflammatory stimuli. Together these results demonstrate that LTR activation provides an additional layer of gene deregulation in classical Hodgkin lymphoma and highlight the potential impact of genome-wide LTR activation in other inflammatory diseases
Viral, bacterial, and fungal infections of the oral mucosa:Types, incidence, predisposing factors, diagnostic algorithms, and management
- Author
- Abell E
- Abu‐Elteen KH
- Akpan A
- Aldred MJ
- Alliegro MB
- Alyassin MA
- Amir J
- Aral SO
- Arendorf TM
- Armstrong JA
- Atespare A
- Atout RN
- Aubert M
- Avitabile E
- Bakker MI
- Balasubramaniam R
- Balfour HH
- Balfour HH
- Bansal R
- Barrett AW
- Baseman JB
- Baughn RE
- Bekondi C
- Belshe RB
- Bennhoff DF
- Bercovitch RS
- Berdicevsky I
- Bergstrom L
- Bernardis F
- Bissessor M
- Blair JE
- Borghi E
- Bosch FX
- Bradsher RW
- Brown BA
- Brown EL
- Brown GD
- Brown JR
- Bruce AJ
- Bruyn KA
- Buchacz K
- Cafarchia C
- Cairns TM
- Calderone RA
- Cannon RD
- Cardosa MJ
- Carlson JA
- CDC
- Centurion‐Lara A
- Centurion‐Lara A
- Chambers MS
- Chang LY
- Chapel TA
- Chapel TA
- Chapel TA
- Chapman SW
- Chatproedprai S
- Chaudhry SI
- Chen S
- Chinn H
- Clay H
- Cohen PR
- Cohen PR
- Communicable Diseases Section Public Health Group
- Cook TM
- Corey L
- Cowan GM
- Crum NF
- Cumberland MC
- Cumming CG
- Cummings MC
- Cutler SJ
- Dalle F
- Davies JC
- Davis JM
- Davis JM
- Dharmshale SN
- Dhingra KK
- Diamond SE
- Dimitrakopoulos I
- Dixon TC
- Dodd CL
- Dohner K
- Domantay‐Apostol GP
- Doumas S
- Dreizen S
- Dreizen S
- Drusin LM
- Dubinsky RM
- Dupont B
- Dupuy AK
- Durry E
- Dusek JJ
- Economopoulou P
- EC‐Clearinghouse on Oral Problems Related to HIV Infection and WHO Collaborating Centre on Oral Manifestations of the Immunodeficiency Virus
- Einsele H
- Ellepola AN
- Emmanuelli JL
- Eng HL
- Eng RH
- Engelkens HJ
- Epstein JB
- Erickson BK
- Erkan AN
- Erlich KS
- Farah CS
- Farah CS
- Fatahzadeh M
- Fatahzadeh M
- Fazili T
- Ferreira OG
- Ficarra G
- Fitzgerald TJ
- Fitzgerald TJ
- Fiumara NJ
- Flaitz CM
- Fleming DT
- Folayan MO
- Fuqua TH
- Galgiani JN
- Galinska EM
- Gerber P
- Ghannoum MA
- Ghannoum MA
- Giannini PJ
- Gilden D
- Gilfillan GD
- Granzow H
- Greenberg MS
- Gromeier M
- Halford WP
- Hanto DW
- Hariri S
- Hartwick RW
- Hayes NS
- Hernandez SL
- Hill C
- Hoang MP
- Hofemeister H
- Holbrook WP
- Holland LE
- Holm P
- Hook EW
- Hook EWR
- Hook LM
- Hopkins S
- Hube B
- Hube B
- Hurt C
- Iatta R
- Ikediobi NI
- Ingraham NR
- Ioannou S
- Ito FA
- Jain P
- Jarvis JN
- Jarvis JN
- Jenson HB
- Johnson DC
- Joseph Wheat L
- Joske RA
- Junkins‐Hopkins JM
- Jutte A
- Kalioras V
- Kang PB
- Kaufman RE
- Kent ME
- Kessenich CR
- Kilmarx PH
- King J
- Koppes GM
- Krawiecka E
- Krishnan PA
- Krishnan PA
- Kullar PJ
- Kutty PK
- Lafferty WE
- Landersdorfer CB
- Larsen SA
- Leader BT
- Leao JC
- Lee JH
- Leib DA
- Leitch EC
- Lerner PI
- Lucas VS
- Luzuriaga K
- Lycke E
- Maeda T
- Magnuson HJ
- Magnuson HJ
- Mahoney JF
- Mahoney JF
- Mandell GL
- Manning DJ
- Marshall B
- Maschmeyer G
- Matsubara VH
- Matsubara VH
- Mayer FL
- McDonough KA
- Memon GA
- Meyer RD
- Mignogna MD
- Miller M
- Milne RS
- Mindel A
- Mitsutake K
- Miyazaki T
- Monod M
- Morgan CA
- Muga R
- Mukherjee A
- Munoz N
- Murciano C
- Mushinski M
- Naglik JR
- Naglik JR
- Nakashima AK
- Nelson BL
- Newman CW
- Ng KH
- Nicola AV
- Nicola AV
- Nunez‐Marti JM
- Obayashi T
- Obayashi T
- Oberste MS
- Ochandiano S
- Oda D
- Oddo D
- Ogata Y
- Ooi MH
- Oostman O
- Ostrosky‐Zeichner L
- Osuji OO
- Pao D
- Park H
- Patel P
- Peeling RW
- Peeling RW
- Pekiner FN
- Perfect JR
- Phan QT
- Philips JA
- Philips JA
- Pierce CG
- Porter SR
- Prabhu SR
- Pulverer G
- Rac MW
- Radolf JD
- Raiziss GW
- Rajcani J
- Ramos‐e‐Silva M
- Ratnam S
- Reichart P
- Reichart PA
- Reichart PA
- Retamal‐Diaz AR
- Reynolds DW
- Rickinson AB
- Riviere GR
- Robinson PG
- Rodrigues DC
- Rodu B
- Romanowski B
- Rosenstein NE
- Ruan Y
- Russell DG
- Saccente M
- Saibene AM
- Samaranayake L
- Samaranayake LP
- Samaranayake LP
- Samaranayake LP
- Sanchez Legaza E
- Sarma N
- Sasaki Y
- Sauerbrei A
- Scarborough M
- Schafer G
- Scheepers A
- Scheepers A
- Scheepers A
- Schmader K
- Scott CM
- Sexually transmitted diseases
- Shannon MT
- Shapiro RS
- Sierra C
- Silverman S
- Singh AE
- Sirisanthana T
- Sitheeque MA
- Smego RA
- Smith JB
- Soderberg‐Naucler C
- Sotgiu G
- Souf S
- Soysa NS
- Stamm LV
- Stamm LV
- Stankus SJ
- Stephens DS
- Stoopler ET
- Stoopler ET
- Stoopler ET
- Stoopler ET
- Stoopler ET
- Strick LB
- Strickler HD
- Suazo PA
- Sun JN
- Taiwo JO
- Tanaka‐Bandoh K
- Thomas DD
- Thomas DD
- Thomas DD
- Thwaites CL
- Tichonova L
- Togni G
- Topazian RG
- Tramont EC
- Tryland M
- Tsang PW
- Tsimis ME
- Turcotte S
- Turner A
- Vaccarella S
- Valour F
- Velicko I
- Vilcins I
- Viragh PA
- Vorasubin N
- Vuyst H
- Wachtler B
- Walsh TJ
- Wang YF
- Watson KM
- Watts DH
- Weiss G
- Weiss HA
- Wel N
- Wendel GD
- Wendel GD
- Wheat J
- Wheat LJ
- Wilkieson C
- Wong VK
- Woods CW
- Woods RG
- Workowski KA
- World Health Organization
- Xia T
- Zakikhany K
- Zaugg C
- Zhu W
- Zhu XP
- Publication venue
- 'Wiley'
- Publication date
- 01/06/2019
- Field of study
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
- Author
- Abbott Bp
- Abbott R
- Abbott Td
- Abraham S
- Acernese F
- Ackley K
- Adams C
- Adhikari Rx
- Adya Vb
- Affeldt C
- Agathos M
- Agatsuma K
- Aggarwal N
- Aguiar Od
- Aiello L
- Ain A
- Ajith P
- Allen G
- Allocca A
- Aloy Ma
- Altin Pa
- Amato A
- Anand S
- Ananyeva A
- Anderson Sb
- Anderson Wg
- Angelova Sv
- Antier S
- Appert S
- Arai K
- Araya Mc
- Areeda Js
- Arene M
- Arnaud N
- Aronson Sm
- Ascenzi S
- Ashton G
- Aston Sm
- Astone P
- Aubin F
- Aufmuth P
- AultONeal K
- Austin C
- Avendano V
- Avila-Alvarez A
- Babak S
- Bacon P
- Badaracco F
- Bader Mkm
- Bae S
- Baird J
- Baker Pt
- Baldaccini F
- Ballardin G
- Ballmer Sw
- Bals A
- Banagiri S
- Barayoga Jc
- Barbieri C
- Barclay Se
- Barish Bc
- Barker D
- Barkett K
- Barnum S
- Barone F
- Barr B
- Barsotti L
- Barsuglia M
- Barta D
- Bartlett J
- Bartos I
- Bassiri R
- Basti A
- Bawaj M
- Bayley Jc
- Bazzan M
- Becsy B
- Bejger M
- Belahcene I
- Bell As
- Beniwal D
- Benjamin Mg
- Berger Bk
- Bergmann G
- Bernuzzi S
- Berry Cpl
- Bersanetti D
- Bertolini A
- Betzwieser J
- Bhandare R
- Bidler J
- Biggs E
- Bilenko Ia
- Bilgili Sa
- Billingsley G
- Birney R
- Birnholtz O
- Biscans S
- Bischi M
- Biscoveanu S
- Bisht A
- Bitossi M
- Bizouard Ma
- Blackburn Jk
- Blackman J
- Blair Cd
- Blair Dg
- Blair Rm
- Bloemen S
- Bobba F
- Bode N
- Boer M
- Boetzel Y
- Bogaert G
- Bondu F
- Bonnand R
- Booker P
- Boom Ba
- Bork R
- Boschi V
- Bose S
- Bossilkov V
- Bosveld J
- Bouffanais Y
- Bozzi A
- Bradaschia C
- Brady Pr
- Bramley A
- Branchesi M
- Brau Je
- Breschi M
- Briant T
- Briggs Jh
- Brighenti F
- Brillet A
- Brinkmann M
- Brockill P
- Brooks Af
- Brooks J
- Brown Dd
- Brunett S
- Buikema A
- Bulik T
- Bulten Hj
- Buonanno A
- Buskulic D
- Bustillo Jc
- Buy C
- Byer Rl
- Cabero M
- Cadonati L
- Cagnoli G
- Cahillane C
- Callister Ta
- Calloni E
- Camp Jb
- Campbell Wa
- Cannon Kc
- Cao H
- Cao J
- Carapella G
- Carbognani F
- Caride S
- Carney Mf
- Carullo G
- Casentini C
- Castro Jmg
- Caudill S
- Cavaglia M
- Cavalier F
- Cavalieri R
- Cella G
- Cerda-Duran P
- Cesarini E
- Chaibi O
- Chakravarti K
- Chamberlin Sj
- Chan M
- Chao S
- Charlton P
- Chase Ea
- Chassande-Mottin E
- Chatterjee D
- Chaturvedi M
- Cheeseboro Bd
- Chen Hy
- Chen X
- Chen Y
- Cheng Hp
- Cheong Ck
- Chia Hy
- Chiadini F
- Chincarini A
- Chiummo A
- Cho G
- Cho Hs
- Cho M
- Christensen N
- Chu Q
- Chua S
- Chung Kw
- Chung S
- Ciani G
- Cieslar M
- Ciobanu Aa
- Ciolfi R
- Cipriano F
- Cirone A
- Clara F
- Clark Ja
- Clearwater P
- Cleva F
- Coccia E
- Cohadon Pf
- Cohen D
- Colleoni M
- Collette Cg
- Collins C
- Colpi M
- Cominsky Lr
- Constancio M
- Conti L
- Cooper Sj
- Corban P
- Corbitt Tr
- Cordero-Carrion I
- Corezzi S
- Corley Kr
- Cornish N
- Corre D
- Corsi A
- Cortese S
- Costa Ca
- Costa Cfd
- Cotesta R
- Coughlin Mw
- Coughlin Sb
- Coulon Jp
- Countryman St
- Couvares P
- Covas Pb
- Cowan Ee
- Coward Dm
- Cowart Mj
- Coyne Dc
- Coyne R
- Creighton Jde
- Creighton Td
- Cripe J
- Croquette M
- Crowder Sg
- Cullen Tj
- Cumming A
- Cunningham L
- Cuoco E
- D'Angelo B
- D'Antonio S
- Dal Canton T
- Dalya G
- Danilishin Sl
- Danzmann K
- Dasgupta A
- Datrier Leh
- Dattilo V
- Dave I
- Davier M
- Davis D
- Daw Ej
- De Laurentis M
- De Pietri R
- De Rosa R
- De Rossi C
- de Varona O
- DeBra D
- Deenadayalan M
- Degallaix J
- Del Pozzo W
- Deleglise S
- DeMarchi Lm
- Demos N
- Dent T
- DeSalvo R
- Dhurandhar S
- Di Fiore L
- Di Giorgio C
- Di Giovanni F
- Di Giovanni M
- Di Girolamo T
- Di Lieto A
- Di Pace S
- Di Palma I
- Di Renzo F
- Diaz Jc
- Diaz Mc
- Dietrich T
- DiFronzo C
- Ding B
- Divakarla Ak
- Dmitriev A
- Doctor Z
- Donovan F
- Dooley Kl
- Doravari S
- Dorrington I
- Downes Tp
- Drago M
- Driggers Jc
- Du Z
- Ducoin Jg
- Dupej P
- Durante O
- Dwyer Se
- Easter Pj
- Eddolls G
- Edo Tb
- Effler A
- Ehrens P
- Eichholz J
- Eikenberry Ss
- Eisenmann M
- Eisenstein Ra
- Errico L
- Essick Rc
- Estelles H
- Estevez D
- Etienne Zb
- Etzel T
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- Evans Tm
- Fafone V
- Fairhurst S
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- Fauchon-Jones Ej
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- Fazio M
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- Ferrante I
- Ferreira Ec
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- Fidecaro F
- Fiori I
- Fiorucci D
- Fishbach M
- Fisher Rp
- Fishner Jm
- Fittipaldi R
- Fitz-Axen M
- Fiumara V
- Flaminio R
- Fletcher M
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- Flynn E
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- Font Ja
- Forsyth Pwf
- Fournier Jd
- Frasca S
- Frasconi F
- Frei Z
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- Frolov Vv
- Fronze G
- Fulda P
- Fyffe M
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- Gadre Bu
- Gaebel Sm
- Gair Jr
- Gammaitoni L
- Gaonkar Sg
- Garcia-Quiros C
- Garufi F
- Gateley B
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- Gennai A
- George D
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- Giacomazzo B
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- Gniesmer J
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- Grote H
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- Gruning P
- Guidi Gm
- Gulati Hk
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- Hannuksela Oa
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- Heitmann H
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- Hinderer T
- Hochheim S
- Hofman D
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- Huynh-Dinh T
- Idzkowski B
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- Littenberg Tb
- Liu J
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- Llorens-Monteagudo M
- Lo Rkl
- London Lt
- Longo A
- Lorenzini M
- Loriette V
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- Lousto Co
- Lovelace G
- Lower Me
- Luck H
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- Lundgren Ap
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- Mansell Gl
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- Markosyan As
- Markowitz A
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- Marsat S
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- Mohapatra Srp
- Molina-Ruiz M
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- Morawski F
- Moreno G
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- Mow-Lowry M
- Muciaccia F
- Mukherjee A
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- Mukherjee S
- Mukund N
- Mullavey A
- Munch J
- Muniz Ea
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- Nagar A
- Nardecchia I
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- Neilson J
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- Nery M
- Neunzert A
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- Ng Ky
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- Nguyen P
- Nichols D
- Nichols Sa
- Nissanke S
- Nocera F
- North C
- Nuttall Lk
- O'Brien Bd
- O'Reilly B
- O'Shaughnessy R
- Obergaulinger M
- Oberling J
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- Ogin Gh
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- Ohme F
- Ohta H
- Okada Ma
- Oliver M
- Oppermann P
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- Ormiston Rg
- Ortega Lf
- Ossokine S
- Ottaway Dj
- Overmier H
- Owen Bj
- Pace Ae
- Pagano G
- Page Ma
- Pagliaroli G
- Pai A
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- Palamos Jr
- Palashov O
- Palomba C
- Pan H
- Panda Pk
- Pang Pth
- Pankow C
- Pannarale F
- Pant Bc
- Paoletti F
- Paoli A
- Parida A
- Parker W
- Pascucci D
- Pasqualetti A
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- Passuello D
- Patil M
- Patricelli B
- Payne E
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- Zimmerman Ab
- Zucker Me
- Zweizig J
- Publication venue
- College Park, MD : American Physical Society
- Publication date
- 01/01/2019
- Field of study
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society
Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model
- Author
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- Zimmerman Ab
- Zucker Me
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2019
- Field of study
We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO’s second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h95%0=3.47×10−25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering
GWTC-2.1: Deep extended catalog of compact binary coalescences observed by LIGO and Virgo during the first half of the third observing run
- Author
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- Zucker ME
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 15/01/2024
- Field of study
The second Gravitational-Wave Transient Catalog, GWTC-2, reported on 39 compact binary coalescences observed by the Advanced LIGO and Advanced Virgo detectors between 1 April 2019 15 ∶ 00 UTC and 1 October 2019 15 ∶ 00 UTC. Here, we present GWTC-2.1, which reports on a deeper list of candidate events observed over the same period. We analyze the final version of the strain data over this period with improved calibration and better subtraction of excess noise, which has been publicly released. We employ three matched-filter search pipelines for candidate identification, and estimate the probability of astrophysical origin for each candidate event. While GWTC-2 used a false alarm rate threshold of 2 per year, we include in GWTC-2.1, 1201 candidates that pass a false alarm rate threshold of 2 per day. We calculate the source properties of a subset of 44 high-significance candidates that have a probability of astrophysical origin greater than 0.5. Of these candidates, 36 have been reported in GWTC-2. We also calculate updated source properties for all binary black hole events previously reported in GWTC-1. If the eight additional high-significance candidates presented here are astrophysical, the mass range of events that are unambiguously identified as binary black holes (both objects ≥ 3 M⊙ ) is increased compared to GWTC-2, with total masses from ∼ 14 M ⊙ for GW190924_021846 to ∼ 182 M⊙ for GW190426_190642. Source properties calculated using our default prior suggest that the primary components of two new candidate events (GW190403_051519 and GW190426_190642) fall in the mass gap predicted by pair-instability supernova theory. We also expand the population of binaries with significantly asymmetric mass ratios reported in GWTC-2 by an additional two events (the mass ratio is less than 0.65 and 0.44 at 90% probability for GW190403_051519 and GW190917_114630 respectively), and find that two of the eight new events have effective inspiral spins χeff > 0 (at 90% credibility), while no binary is consistent with χeff < 0 at the same significance. We provide updated estimates for rates of binary black hole and binary neutron star coalescence in the local Universe
All-sky, all-frequency directional search for persistent gravitational waves from Advanced LIGO’s and Advanced Virgo’s first three observing runs
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- Zucker ME
- Zweizig J
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 03/06/2022
- Field of study
We present the first results from an all-sky all-frequency (ASAF) search for
an anisotropic stochastic gravitational-wave background using the data from the
first three observing runs of the Advanced LIGO and Advanced Virgo detectors.
Upper limit maps on broadband anisotropies of a persistent stochastic
background were published for all observing runs of the LIGO-Virgo detectors.
However, a broadband analysis is likely to miss narrowband signals as the
signal-to-noise ratio of a narrowband signal can be significantly reduced when
combined with detector output from other frequencies. Data folding and the
computationally efficient analysis pipeline, {\tt PyStoch}, enable us to
perform the radiometer map-making at every frequency bin. We perform the search
at 3072 {\tt{HEALPix}} equal area pixels uniformly tiling the sky and in every
frequency bin of width 1/32~Hz in the range 20−1726~Hz, except for bins
that are likely to contain instrumental artefacts and hence are notched. We do
not find any statistically significant evidence for the existence of narrowband
gravitational-wave signals in the analyzed frequency bins. Therefore, we place
95% confidence upper limits on the gravitational-wave strain for each
pixel-frequency pair, the limits are in the range (0.030−9.6)×10−24. In addition, we outline a method to identify candidate
pixel-frequency pairs that could be followed up by a more sensitive (and
potentially computationally expensive) search, e.g., a matched-filtering-based
analysis, to look for fainter nearly monochromatic coherent signals. The ASAF
analysis is inherently independent of models describing any spectral or spatial
distribution of power. We demonstrate that the ASAF results can be
appropriately combined over frequencies and sky directions to successfully
recover the broadband directional and isotropic results
All-sky search for continuous gravitational waves from isolated neutron stars in the early O3 LIGO data
- Author
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- Abbott TD
- Abraham S
- Acernese F
- Ackley K
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- Adya VB
- Affeldt C
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- Aleman KM
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- Amato A
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- Arnaud N
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- Xu W-R
- Yamada T
- Yamamoto H
- Yamamoto Kazuhiro
- Yamamoto Kohei
- Yamamoto T
- Yamashita K
- Yamazaki R
- Yang FW
- Yang L
- Yang Yang
- Yang Yi
- Yang Z
- Yap MJ
- Yeeles DW
- Yelikar AB
- Ying M
- Yokogawa K
- Yokoyama J
- Yokozawa T
- Yoon A
- Yoshioka T
- Yu Hang
- Yu Haocun
- Yuzurihara H
- Zanolin M
- Zeidler S
- Zelenova T
- Zendri J-P
- Zevin M
- Zhan M
- Zhang H
- Zhang J
- Zhang L
- Zhang R
- Zhang T
- Zhao C
- Zhao G
- Zhao Yue
- Zhao Yuhang
- Zhou Z
- Zhu XJ
- Zhu Z-H
- Zucker ME
- Zweizig J
- Publication venue
- AMER PHYSICAL SOC
- Publication date
- 15/10/2021
- Field of study
We report on an all-sky search for continuous gravitational waves in the frequency band 20-2000 Hz and with a frequency time derivative in the range of [-1.0,+0.1]×10-8 Hz/s. Such a signal could be produced by a nearby, spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the LIGO data from the first six months of Advanced LIGO's and Advanced Virgo's third observational run, O3. No periodic gravitational wave signals are observed, and 95% confidence-level (C.L.) frequentist upper limits are placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are ∼1.7×10-25 near 200 Hz. For a circularly polarized source (most favorable orientation), the lowest upper limits are ∼6.3×10-26. These strict frequentist upper limits refer to all sky locations and the entire range of frequency derivative values. For a population-averaged ensemble of sky locations and stellar orientations, the lowest 95% C.L. upper limits on the strain amplitude are ∼1.4×10-25. These upper limits improve upon our previously published all-sky results, with the greatest improvement (factor of ∼2) seen at higher frequencies, in part because quantum squeezing has dramatically improved the detector noise level relative to the second observational run, O2. These limits are the most constraining to date over most of the parameter space searched
Search for gravitational waves associated with gamma-ray bursts detected by Fermi and Swift during the LIGO–Virgo run O3b
- Author
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- Zhu Z-H
- Zimmerman AB
- Zucker ME
- Zweizig J
- Publication venue
- 'American Astronomical Society'
- Publication date
- 01/01/2022
- Field of study
We search for gravitational-wave signals associated with gamma-ray bursts (GRBs) detected by the Fermi and Swift satellites during the second half of the third observing run of Advanced LIGO and Advanced Virgo (2019 November 1 15:00 UTC–2020 March 27 17:00 UTC). We conduct two independent searches: a generic gravitational-wave transients search to analyze 86 GRBs and an analysis to target binary mergers with at least one neutron star as short GRB progenitors for 17 events. We find no significant evidence for gravitational-wave signals associated with any of these GRBs. A weighted binomial test of the combined results finds no evidence for subthreshold gravitational-wave signals associated with this GRB ensemble either. We use several source types and signal morphologies during the searches, resulting in lower bounds on the estimated distance to each GRB. Finally, we constrain the population of low-luminosity short GRBs using results from the first to the third observing runs of Advanced LIGO and Advanced Virgo. The resulting population is in accordance with the local binary neutron star merger rate
Mucopolysaccharidoses: early diagnostic signs in infants and children
- Author
- A Caciotti
- A Fiumara
- A Tylki-Szymańska
- Agata Fiumara
- AM Montano
- AM Montaño
- Annalisa Madeo
- BT Kiely
- Bénédicte Héron
- Cinzia Galimberti
- CJ Hendriksz
- CJ Hendriksz
- EF Neufeld
- F Bertola
- F Lonardo
- FA Wijburg
- FD Nidiffer
- ID Young
- JE Wraith
- JM Trowbridge
- M Beck
- M Scarpa
- Maja Di Rocco
- MC Bax
- MJ Valstar
- NJ Mendelsohn
- R Martin
- R Parini
- RA Pfeiffer
- RW Peake
- SA Khan
- TA Dam
- V Valayannopoulos
- WS Sly
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
- …