1,430 research outputs found

    Effect of influenza-induced fever on human bioimpedance values

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    BACKGROUND AND AIMS: Bioelectrical impedance analysis (BIA) is a widely used technique to assess body composition and nutritional status. While bioelectrical values are affected by diverse variables, there has been little research on validation of BIA in acute illness, especially to understand prognostic significance. Here we report the use of BIA in acute febrile states induced by influenza. METHODS: Bioimpedance studies were conducted during an H1N1 influenza A outbreak in Venezuelan Amerindian villages from the Amazonas. Measurements were performed on 52 subjects between 1 and 40 years of age, and 7 children were re-examined after starting Oseltamivir treatment. Bioelectrical Impedance Vector Analysis (BIVA) and permutation tests were applied. RESULTS: For the entire sample, febrile individuals showed a tendency toward greater reactance (p=0.058) and phase angle (p=0.037) than afebrile individuals, while resistance and impedance were similar in the two groups. Individuals with repeated measurements showed significant differences in bioimpedance values associated with fever, including increased reactance (p<0.001) and phase angle (p=0.007), and decreased resistance (p=0.007) and impedance (p<0.001). CONCLUSIONS: There are bioelectrical variations induced by influenza that can be related to dehydration, with lower extracellular to intracellular water ratio in febrile individuals, or a direct thermal effect. Caution is recommended when interpreting bioimpedance results in febrile states

    Influencia de la evaluación del desempeño directivo y su efectividad en la gestión pública de la educación escolar

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    The current challenges in a globalized society imply that schools provide quality education, with efficient and effective services, establishing performance policies that contribute to the effectiveness of educational management. This article analyzes said management performance policies and their influence on the effectiveness of public management of school education. For this, the analytical-synthetic method was applied, in order to analyze and synthesize the relevance of the written theory regarding managerial performance and the effectiveness of public management. The results were identified that the effectiveness of school management is achieved with the interaction of factors that allow raising educational quality, likewise the evaluation of managerial performance, is another component that contributes to this effectiveness. It is concluded that the evaluation directly influences the effectiveness of school management, therefore, it is necessary for managers to permanently submit to evaluations, through performance indicators, as this allows to measure the entire process, and show whether the manager fulfilled the competencies inherent to the position he holds.Los retos actuales en una sociedad globalizada, implican que las escuelas brinden una educación de calidad, con servicios de eficiencia y eficacia, estableciendo políticas de desempeño que aporten a la efectividad de la gestión educativa. Este artículo analiza dichas políticas de desempeño directivo y su influencia en la efectividad de la gestión pública de la educación escolar. Para ello, se aplicó el método analítico-sintético, a fin de analizar y sintetizar lo relevante de la teoría escrita respecto al desempeño directivo y la efectividad de la gestión pública. Se identificaron como resultados que la efectividad de la gestión escolar se logra con la interacción de la eficacia y la eficiencia, por lo tanto, permite elevar la calidad educativa; así mismo la evaluación de desempeño directivo, es otro componente que contribuye a esta efectividad. Se concluye, que la evaluación influye directamente en la efectividad de la gestión escolar, por lo que, es necesario que los directivos se sometan permanentemente a las evaluaciones, a través de indicadores de desempeño, pues esto permite medir todo el proceso, y evidenciar si el directivo cumplió con las competencias inherentes al cargo que desempeña

    Trypanosoma rangeli is phylogenetically closer to Old World trypanosomes than to Trypanosoma cruzi.

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    This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Trypanosoma rangeli and Trypanosoma cruzi are generalist trypanosomes sharing a wide range of mammalian hosts; they are transmitted by triatomine bugs, and are the only trypanosomes infecting humans in the Neotropics. Their origins, phylogenetic relationships, and emergence as human parasites have long been subjects of interest. In the present study, taxon-rich analyses (20 trypanosome species from bats and terrestrial mammals) using ssrRNA, glycosomal glyceraldehyde-3-phosphate dehydrogenase (gGAPDH), heat shock protein-70 (HSP70) and Spliced Leader RNA sequences, and multilocus phylogenetic analyses using 11 single copy genes from 15 selected trypanosomes, provide increased resolution of relationships between species and clades, strongly supporting two main sister lineages: lineage Schizotrypanum, comprising T. cruzi and bat-restricted trypanosomes, and Tra[Tve-Tco] formed by T. rangeli, Trypanosoma vespertilionis and Trypanosoma conorhini clades. Tve comprises European T. vespertilionis and African T. vespertilionis-like of bats and bat cimicids characterised in the present study and Trypanosoma sp. Hoch reported in monkeys and herein detected in bats. Tco included the triatomine-transmitted tropicopolitan T. conorhini from rats and the African NanDoum1 trypanosome of civet (carnivore). Consistent with their very close relationships, Tra[Tve-Tco] species shared highly similar Spliced Leader RNA structures that were highly divergent from those of Schizotrypanum. In a plausible evolutionary scenario, a bat trypanosome transmitted by cimicids gave origin to the deeply rooted Tra[Tve-Tco] and Schizotrypanum lineages, and bat trypanosomes of diverse genetic backgrounds jumped to new hosts. A long and independent evolutionary history of T. rangeli more related to Old World trypanosomes from bats, rats, monkeys and civets than to Schizotrypanum spp., and the adaptation of these distantly related trypanosomes to different niches of shared mammals and vectors, is consistent with the marked differences in transmission routes, life-cycles and host-parasite interactions, resulting in T. cruzi (but not T. rangeli) being pathogenic to humans.This study was supported by grants awarded to MMGT and EPC from CNPq (National Council for Scientific and Technological Development) PROAFRICA, PROSUL and UNIVERSAL programs, CAPES (Coordination for the Improvement of Higher Education Personnel) PNIPB, PNPD and PROTAX programs, and FAPESP (São Paulo Research Foundation; process 2016/07487-0). Genome sequencing was supported by the Assembling the Tree of Life (ATOL) Project of the National Science Foundation, USA (NSF DEB-0830056), and TCC-USP (Trypanosomatid Culture Collection of the University of São Paulo) projects. OEA received PhD fellowships from CNPq (PROTAX) and COLCIENCIAS (Administrative Department of Science, Technology and Innovation, Colombia); PAO is a postdoctoral fellow of CAPES (PNPD); LL and AGCM are supported by a postdoctoral fellowship from CAPES (PROTAX)

    Effects of husbandry parameters on the life-history traits of the apple snail, Marisa cornuarietis: effects of temperature, photoperiod, and population density

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    These experiments are part of a larger study designed to investigate the influence of husbandry parameters on the life history of the apple snail, Marisa cornuarietis. The overall objective of the program is to identify suitable husbandry conditions for maintaining multi-generation populations of this species in the laboratory for use in ecotoxicological testing. In this article, we focus on the effects of photoperiod, temperature, and population density on adult fecundity and juvenile growth. Increasing photoperiod from 12 to 16 h of light per day had no effect on adult fecundity or egg hatching and relatively minor effects on juvenile growth and development. Rearing snails at temperatures between 22°C and 28°C did not influence the rates of egg production or egg clutch size. However, the rates of growth and development (of eggs and juveniles) increased with increasing temperature in this range, and when temperatures were reduced to 22°C egg-hatching success was impaired. Juvenile growth and development were more sensitive to rearing density than adult fecundity traits. On the basis of the present results, we conclude that rearing individuals of M. cornuarietis at a temperature of 25°C, a photoperiod of 12L:12D, and a density of <0.8 snails L−1 (with lower densities for juvenile snails) should provide favorable husbandry conditions for maintaining multi-generation populations of this species

    Evolution of Th2 responses : Characterization of IL-4/13 in sea bass (Dicentrarchus labrax L.) and studies of expression and biological activity

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    Acknowledgements This research was funded by the European Commission under the 7th Framework Programme for Research and Technological Development (FP7) of the European Union (Grant Agreement 311993 TARGETFISH). T.W. received funding from the MASTS pooling initiative (The Marine Alliance for Science and Technology for Scotland). MASTS is funded by the Scottish Funding Council (grant reference number HR09011) and contributing institutions.Peer reviewedPublisher PD

    A large-scale study of a poultry trading network in Bangladesh: implications for control and surveillance of avian influenza viruses

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    Since its first report in 2007, avian influenza (AI) has been endemic in Bangladesh. While live poultry marketing is widespread throughout the country and known to influence AI dissemination and persistence, trading patterns have not been described. The aim of this study is to assess poultry trading practices and features of the poultry trading networks which could promote AI spread, and their potential implications for disease control and surveillance. Data on poultry trading practices was collected from 849 poultry traders during a cross-sectional survey in 138 live bird markets (LBMs) across 17 different districts of Bangladesh. The quantity and origins of traded poultry were assessed for each poultry type in surveyed LBMs. The network of contacts between farms and LBMs resulting from commercial movements of live poultry was constructed to assess its connectivity and to identify the key premises influencing it

    New perspectives for sustainable resource and energy use, management and transformation: approaches from green and sustainable chemistry and engineering

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    The special volume on green and sustainable chemistry and engineering has fourteen papers that were considered relevant to the present day issues and discussion, such as adequate use of raw materials and efficient energy, besides considering renewable sources for materials and energy; and changing economical canons towards circular economy. Businesses, governments and Society are facing a number of challenges to tread the sustainability path and provide wellbeing for future generations. This special volume relevance provides discussions and contributions to foster that desirable future. Chemicals are ubiquitous in everyday activities. Their widespread presence provides benefits to societies’ wellbeing, but can have some deleterious effects. To counteract such effect, green engineering and sustainable assessment in industrial processes have been gathering momentum in the last thirty years. Green chemistry, green engineering, eco-efficiency, and sustainability are becoming a necessity for assessing and managing products and processes in the chemical industry. This special volume presents fourteen articles related to sustainable resource and energy use (five articles), circular economy (one article), cleaner production and sustainable process assessment (five article), and innovation in chemical products (three articles). Green and sustainable chemistry, as well as sustainable chemical engineering and renewable energy sources are required to foster and consolidate a transition towards more sustainable societies. This special volume present current trends in chemistry and chemical engineering, such as sustainable resource and energy use, circular economy, cleaner production and sustainable process assessment, and innovation in chemical products. This special volume provides insights in this direction and complementing other efforts towards such transition
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