23,589 research outputs found
Low Dose Aspirin: An Effective Chemoprophylaxis for Preventing Venous Thromboembolic Events
The available guidelines, endorsed by Surgical Care Improvement Project (SCIP), have advocated that aspirin (ASA) is a safe and effective strategy for venous thromboembolic events (VTE) prophylaxis following total joint arthroplasty (TJA). The optimal dose of aspirin for this purpose is not known. The first guidelines for prevention of VTE that were issued by the American Academy of Orthopedic Surgeons recommended 325 mg Bis in die (twice a day) (bid) for this purpose with the recommendation having a 1C grade (little evidence to support the recommendation). It is known that platelet aggregation inhibition occurs at lower doses. Traditionally, ASA 81mg has been used as a cardioprotective medication. Additionally, all available randomized studies, including the sentinel study on Pulmonary Embolism Prevention (PEP) trial1-4 have used lower doses of ASA. It was our hypothesis that lower dose aspirin is likely to be as effective as higher dose aspirin while reducing the gastrointestinal side effects associated with the higher dose aspirin
Mapping photonic entanglement into and out of a quantum memory
Recent developments of quantum information science critically rely on
entanglement, an intriguing aspect of quantum mechanics where parts of a
composite system can exhibit correlations stronger than any classical
counterpart. In particular, scalable quantum networks require capabilities to
create, store, and distribute entanglement among distant matter nodes via
photonic channels. Atomic ensembles can play the role of such nodes. So far, in
the photon counting regime, heralded entanglement between atomic ensembles has
been successfully demonstrated via probabilistic protocols. However, an
inherent drawback of this approach is the compromise between the amount of
entanglement and its preparation probability, leading intrinsically to low
count rate for high entanglement. Here we report a protocol where entanglement
between two atomic ensembles is created by coherent mapping of an entangled
state of light. By splitting a single-photon and subsequent state transfer, we
separate the generation of entanglement and its storage. After a programmable
delay, the stored entanglement is mapped back into photonic modes with overall
efficiency of 17 %. Improvements of single-photon sources together with our
protocol will enable "on demand" entanglement of atomic ensembles, a powerful
resource for quantum networking.Comment: 7 pages, and 3 figure
Decoherence-free subspace and disentanglement dynamics for two qubits in a common non-Markovian squeezed reservoir
We study the non-Markovian entanglement dynamics of two qubits in a common
squeezed bath. We see remarkable difference between the non-Markovian
entanglement dynamics with its Markovian counterpart. We show that a
non-Markovian decoherence free state is also decoherence free in the Markovian
regime, but all the Markovian decoherence free states are not necessarily
decoherence free in the non-Markovian domain. We extend our calculation from
squeezed vacuum bath to squeezed thermal bath, where we see the effect of
finite bath temperatures on the entanglement dynamics.Comment: To appear in Phys. Rev. A (8 pages
Comparing generalized and specific problematic smartphone/internet use: longitudinal relationships between smartphone application- based addiction and social media addiction and psychological distress
Background and aims: The literature has proposed two types of problematic smartphone/internet use: generalized problematic use and specific problematic use. However, longitudinal findings on the associations between the two types of problematic use and psychological distress are lacking among East-Asians. The present study examined temporal associations between both generalized and specific problematic use of the smartphone/internet, and psychological distress.
Methods: Hong Kong University students (N 5 308; 100 males; mean age 5 23.75 years; SD ± 5.15) were recruited with follow-ups at three, six, and nine months after baseline assessment. All participants completed the Smartphone Application-Based Addiction Scale (for generalized problematic smartphone/internet use), the Bergen Social Media Addiction Scale (for specific problematic smartphone/internet use), and the Hospital Anxiety and Depression Scale (for psychological distress) in each assessment. Latent growth modeling (LGM) was constructed to understand temporal associations between generalized/specific problematic use and psychological distress.
Results: The LGM suggested that the intercept of generalized problematic use was significantly associated with the intercept of psychological distress (standardized coefficient [b] 5 0.32; P < 0.01). The growth of generalized problematic use was significantly associated with the growth of psychological distress (b 5 0.51; P < 0.01). Moreover, the intercept of specific problematic use was significantly associated with the intercept of psychological distress (b 5 0.28; P < 0.01) and the growth of psychological distress (b 5 0.37; P < 0.01).
Conclusion: The initial level of problematic use of the smartphone/internet may prevent psychological distress
Memory-built-in quantum teleportation with photonic and atomic qubits
The combination of quantum teleportation and quantum memory of photonic
qubits is essential for future implementations of large-scale quantum
communication and measurement-based quantum computation. Both steps have been
achieved separately in many proof-of-principle experiments, but the
demonstration of memory-built-in teleportation of photonic qubits remains an
experimental challenge. Here, we demonstrate teleportation between photonic
(flying) and atomic (stationary) qubits. In our experiment, an unknown
polarization state of a single photon is teleported over 7 m onto a remote
atomic qubit that also serves as a quantum memory. The teleported state can be
stored and successfully read out for up to 8 micro-second. Besides being of
fundamental interest, teleportation between photonic and atomic qubits with the
direct inclusion of a readable quantum memory represents a step towards an
efficient and scalable quantum network.Comment: 19 pages 3 figures 1 tabl
A genetic contribution from the Far East into Ashkenazi Jews via the ancient Silk Road
Contemporary Jews retain a genetic imprint from their Near Eastern ancestry, but obtained substantial genetic components from their neighboring populations during their history. Whether they received any genetic contribution from the Far East remains unknown, but frequent communication with the Chinese has been observed since the Silk Road period. To address this issue, mitochondrial DNA (mtDNA) variation from 55,595 Eurasians are analyzed. The existence of some eastern Eurasian haplotypes in eastern Ashkenazi Jews supports an East Asian genetic contribution, likely from Chinese. Further evidence indicates that this connection can be attributed to a gene flow event that occurred less than 1.4 kilo-years ago (kya), which falls within the time frame of the Silk Road scenario and fits well with historical records and archaeological discoveries. This observed genetic contribution from Chinese to Ashkenazi Jews demonstrates that the historical exchange between Ashkenazim and the Far East was not confined to the cultural sphere but also extended to an exchange of genes
Polypyrrole-Fe2O3 nanohybrid materials for electrochemical storage
We report on the synthesis and electrochemical characterization of nanohybrid polypyrrole (PPy) (PPy/Fe2O3) materials for electrochemical storage applications. We have shown that the incorporation of nanoparticles inside the PPy notably increases the charge storage capability in comparison to the “pure” conducting polymer. Incorporation of large anions, i.e., paratoluenesulfonate, allows a further improvement in the capacity. These charge storage modifications have been attributed to the morphology of the composite in which the particle sizes and the specific surface area are modified with the incorporation of nanoparticles. High capacity and stability have been obtained in PC/NEt4BF4 (at 20 mV/s), i.e., 47 mAh/g, with only a 3% charge loss after one thousand cyles. The kinetics of charge–discharge is also improved by the hybrid nanocomposite morphology modifications, which increase the rate of insertion–expulsion of counter anions in the bulk of the film. A room temperature ionic liquid such as imidazolium trifluoromethanesulfonimide seems to be a promising electrolyte because it further increases the capacity up to 53 mAh/g with a high stability during charge–discharge processes
Solving Quantum Ground-State Problems with Nuclear Magnetic Resonance
Quantum ground-state problems are computationally hard problems; for general
many-body Hamiltonians, there is no classical or quantum algorithm known to be
able to solve them efficiently. Nevertheless, if a trial wavefunction
approximating the ground state is available, as often happens for many problems
in physics and chemistry, a quantum computer could employ this trial
wavefunction to project the ground state by means of the phase estimation
algorithm (PEA). We performed an experimental realization of this idea by
implementing a variational-wavefunction approach to solve the ground-state
problem of the Heisenberg spin model with an NMR quantum simulator. Our
iterative phase estimation procedure yields a high accuracy for the
eigenenergies (to the 10^-5 decimal digit). The ground-state fidelity was
distilled to be more than 80%, and the singlet-to-triplet switching near the
critical field is reliably captured. This result shows that quantum simulators
can better leverage classical trial wavefunctions than classical computers.Comment: 11 pages, 13 figure
Experimental Quantum Teleportation of a Two-Qubit Composite System
Quantum teleportation, a way to transfer the state of a quantum system from
one location to another, is central to quantum communication and plays an
important role in a number of quantum computation protocols. Previous
experimental demonstrations have been implemented with photonic or ionic
qubits. Very recently long-distance teleportation and open-destination
teleportation have also been realized. Until now, previous experiments have
only been able to teleport single qubits. However, since teleportation of
single qubits is insufficient for a large-scale realization of quantum
communication and computation2-5, teleportation of a composite system
containing two or more qubits has been seen as a long-standing goal in quantum
information science. Here, we present the experimental realization of quantum
teleportation of a two-qubit composite system. In the experiment, we develop
and exploit a six-photon interferometer to teleport an arbitrary polarization
state of two photons. The observed teleportation fidelities for different
initial states are all well beyond the state estimation limit of 0.40 for a
two-qubit system. Not only does our six-photon interferometer provide an
important step towards teleportation of a complex system, it will also enable
future experimental investigations on a number of fundamental quantum
communication and computation protocols such as multi-stage realization of
quantum-relay, fault-tolerant quantum computation, universal quantum
error-correction and one-way quantum computation.Comment: 16pages, 4 figure
The Quantum Internet
Quantum networks offer a unifying set of opportunities and challenges across
exciting intellectual and technical frontiers, including for quantum
computation, communication, and metrology. The realization of quantum networks
composed of many nodes and channels requires new scientific capabilities for
the generation and characterization of quantum coherence and entanglement.
Fundamental to this endeavor are quantum interconnects that convert quantum
states from one physical system to those of another in a reversible fashion.
Such quantum connectivity for networks can be achieved by optical interactions
of single photons and atoms, thereby enabling entanglement distribution and
quantum teleportation between nodes.Comment: 15 pages, 6 figures Higher resolution versions of the figures can be
downloaded from the following link:
http://www.its.caltech.edu/~hjkimble/QNet-figures-high-resolutio
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