77 research outputs found
The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers.
- Author
- A Liberzon
- A SabĂČ
- A Schaub
- AD Gitlin
- AD Gitlin
- AM Bolger
- BD Berkovits
- C Chou
- C Gooding
- C Trapnell
- Christopher W. J. Smith
- CJ David
- CR Jung
- CY Huang
- D Anastasiou
- D Dominguez-Sola
- D Dominguez-Sola
- D Kim
- D Kim
- DP Calado
- E Eden
- E Hobeika
- Elisa MonzĂłn-Casanova
- FE Baralle
- FJ Dufort
- GD Victora
- Greta Lamers
- J Ersching
- J König
- J Porta La
- J Suckale
- JF Porter
- JK Vuong
- K Kwon
- K Sawicka
- K Suzuki
- KP Knoch
- KP Knoch
- L Mesin
- L Quéméneur
- LN Chan
- LY Tan
- M Boothby
- M Cortés
- M Shibayama
- MA Hogenbirk
- Manuel D. DĂaz-Muñoz
- Martin Turner
- MD Diaz-Muñoz
- MI Love
- Michael Screen
- Michele Solimena
- MK Zeman
- N Keppetipola
- NM Martinez
- O Bannard
- PD Pioli
- PL Boutz
- Q Li
- R Spellman
- Richard M. R. Coulson
- S Anders
- S Sander
- S Shen
- S Vavassori
- Sarah E. Bell
- SR Hann
- T Inoue
- TL Dayton
- U Nowak
- X Chang
- Y Ke
- Y Shinkai
- Z Xia
- Publication venue
- Nature Immunology
- Publication date
- 22/01/2018
- Field of study
Antibody affinity maturation occurs in germinal centers (GCs), where B cells cycle between the light zone (LZ) and the dark zone. In the LZ, GC B cells bearing immunoglobulins with the highest affinity for antigen receive positive selection signals from helper T cells, which promotes their rapid proliferation. Here we found that the RNA-binding protein PTBP1 was needed for the progression of GC B cells through late S phase of the cell cycle and for affinity maturation. PTBP1 was required for proper expression of the c-MYC-dependent gene program induced in GC B cells receiving T cell help and directly regulated the alternative splicing and abundance of transcripts that are increased during positive selection to promote proliferation
Mechanism of Splicing Regulation of Spinal Muscular Atrophy Genes
- Author
- A Aartsma-Rus
- A Cléry
- A Echaniz-Laguna
- A Moursy
- B Boda
- B Heinrich
- B Raj
- B Wirth
- BG Burnett
- C Daniel
- C dâYdewalle
- CD Wee
- CE Dominguez
- CF Rochette
- CJ Woo
- CL Lorson
- CL Lorson
- D Germain-Desprez
- D Ronchi
- DM Liang
- EW Ottesen
- EW Ottesen
- EW Ottesen
- EY Osman
- FM Jodelka
- H Miyajima
- H Miyaso
- H-H Chen
- HY Xiong
- I Beusch
- J Glascock
- J Klar
- J Li
- J Schmutz
- J Seo
- J Seo
- J Seo
- J Seo
- J Vitte
- JK Bose
- JM Kiel
- JM Oh
- JR Taube
- K Zarnack
- KJ Hertel
- L Cartegni
- L Cartegni
- L Conti De
- L Wan
- LA Nash
- LC Sutherland
- LIG Acuña
- M Bouttier
- M Bowerman
- M Cucchiarini
- M DeschĂȘnes
- M Vezain
- MC Wahl
- MD DĂaz-Muñoz
- MD Howell
- MD Howell
- MD Howell
- MJA Wood
- ML Hastings
- MV Heck
- N Rodriguez-Muela
- NK Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- NN Singh
- P Deininger
- P Förch
- PJ Shepard
- PJ Young
- R Martinez-Contreras
- R Sorek
- R Spellman
- R Xiao
- RN Singh
- RN Singh
- RN Singh
- RN Singh
- S Ahmad
- S Cho
- S Cho
- S Erkelenz
- S Irimura
- S Lefebvre
- S Pedrotti
- S Sivanesan
- SC Cho
- SC Huelga
- SR Lim
- T AktaĆ
- T Kashima
- T Kashima
- T Kashima
- T Saldi
- T Vanderweyde
- TA Cooper
- TD Baughan
- TKd Doktor
- TY Liu
- UR Monani
- UR Monani
- V Hirsch-Reinshagen
- V Setola
- X Wu
- XD Fu
- Y Hofmann
- Y Hofmann
- Y Hua
- Y Hua
- Y Lee
- Y Mende
- YC Chen
- Z Sheng-Yuan
- Publication venue
- Iowa State University Digital Repository
- Publication date
- 01/01/2018
- Field of study
Spinal muscular atrophy (SMA) is one of the major genetic disorders associated with infant mortality. More than 90% cases of SMA result from deletions or mutations of Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN1, does not compensate for the loss of SMN1due to predominant skipping of exon 7. However, correction of SMN2 exon 7 splicing has proven to confer therapeutic benefits in SMA patients. The only approved drug for SMA is an antisense oligonucleotide (Spinrazaâą/Nusinersen), which corrects SMN2 exon 7 splicing by blocking intronic splicing silencer N1 (ISS-N1) located immediately downstream of exon 7. ISS-N1 is a complex regulatory element encompassing overlapping negative motifs and sequestering a cryptic splice site. More than 40 protein factors have been implicated in the regulation of SMN exon 7 splicing. There is evidence to support that multiple exons of SMN are alternatively spliced during oxidative stress, which is associated with a growing number of pathological conditions. Here, we provide the most up to date account of the mechanism of splicing regulation of the SMN genes
Serotype distribution of remaining pneumococcal meningitis in the mature PCV10/13 period: Findings from the PSERENADE Project
- Author
- Almeida SCG
- Amin-Chowdhury Z
- Ampofo K
- Ang M
- Bar-Zeev N
- Bennett JC
- Born R
- Brandileone MCC
- Bruce MG
- Bruden D
- Byington CL
- Cameron C
- Camilli R
- Castilla J
- ChacĂłn GC
- Chan G
- Chow KH
- Ciruela P
- Cohen AL
- Cohen C
- Corcoran M
- Dagan R
- Dalby T
- Danis K
- de Gouveia L
- de Miguel S
- De Wals P
- Deceuninck G
- Del Manso M
- Desmet S
- Diawara I
- Dimina E
- DĂaz J
- Erlendsdottir H
- Feikin DR
- Gierke R
- Givon-Lavi N
- Guevara M
- Hammitt LL
- Hayford K
- Hilty M
- Ho PL
- Jayasinghe S
- Kellner JD
- Kleynhans J
- Knol MJ
- Knoll MD
- Kristinsson KG
- Ladhani SN
- Lefebvre B
- McGeer A
- Mereckiene J
- Muñoz-Almagro C
- Mwenda JM
- Napoli D
- Nzoyikorera N
- Oishi K
- Pekka Nuorti J
- Pelton SI
- Pennington K
- Peterson ME
- Pilishvili T
- Ploy MC
- Puentes R
- Quesada MG
- Ricketson LJ
- Sanz JC
- Savrasova L
- Setchanova LP
- Smith A
- Suga S
- Sutcliffe CG
- Swarthout TD
- Thoon KC
- Toropainen M
- Valentiner-Branth P
- Valenzuela MT
- van der Linden M
- van Sorge NM
- Varon E
- Vestrheim DF
- von Gottberg A
- Winje BA
- Yang Y
- Yildirim I
- Zeger SL
- Zintgraff J
- Publication venue
- Publication date
- 01/04/2021
- Field of study
Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the serotype distribution of remaining pneumococcal meningitis in countries using PCV10/13 for least 5-7 years with primary series uptake above 70%. The distribution was estimated using a multinomial Dirichlet regression model, stratified by PCV product and age. In PCV10-using sites (N = 8; cases = 1141), PCV10 types caused 5% of cases <5 years of age and 15% among â„5 years; the top serotypes were 19A, 6C, and 3, together causing 42% of cases <5 years and 37% â„5 years. In PCV13-using sites (N = 32; cases = 4503), PCV13 types caused 14% in <5 and 26% in â„5 years; 4% and 13%, respectively, were serotype 3. Among the top serotypes are five (15BC, 8, 12F, 10A, and 22F) included in higher-valency PCVs under evaluation. Other top serotypes (24F, 23B, and 23A) are not in any known investigational product. In countries with mature vaccination programs, the proportion of pneumococcal meningitis caused by vaccine-in-use serotypes is lower (â€26% across all ages) than pre-PCV (â„70% in children). Higher-valency PCVs under evaluation target over half of remaining pneumococcal meningitis cases, but questions remain regarding generalizability to the African meningitis belt where additional data are needed
The management of acute venous thromboembolism in clinical practice. Results from the European PREFER in VTE Registry
- Author
- Abbadie F
- Achkar A
- Ackroyd A
- Adamczyk A
- Adarraga Cansino Md
- Addala A
- Adnet F
- Agarwal G
- Ageno W
- Agnelli G
- Agnelli G
- Al Ahmad W
- Al-Refaie F
- Alexandra Jf
- Alikhan R
- Allameddine A
- Altarriba Es
- Amado FernĂĄndez C
- Amitrano M
- Amore M
- Angelini E
- Antignani Pl
- Aquilanti S
- Aranda Blazquez R
- Arden C
- Arellano Rodrigo E
- Armengou Arxe A
- Arone A
- Asaro G
- Attanzio Mt
- Attinasi V
- Austin A
- Axthelm C
- Axthelm P
- Bakhai A
- Balbarini A
- Ballaz Quincoces A
- Banfi E
- Banyai M
- Barcellona D
- Barillari G
- Bartolini C
- Barton T
- Bartone M
- Bauersachs R
- Bauersachs R
- Beato PĂ©rez Jl
- Bedate DĂaz P
- Belhassane A
- Bellanuova I
- Bellisi M
- Bellizzi A
- Benaroya B
- Bergmann K
- Berremili T
- Beschorner U
- Bianchi M
- Bianchini G
- Binias Kh
- Birr V
- Blanco-Molina Ma
- Boari B
- Body R
- Bonnin C
- Boral M
- Bortoluzzi C
- Bosler F
- Bramlage P
- Bratsch H
- Brauer G
- Bresin Durand Mg
- Brisot D
- Brodmann M
- Brousse C
- Brucoli C
- Burghard S
- Calandra G
- Calvo Mijares N
- Camporese G
- Canafoglia L
- Cancellieri E
- Cannavacciuolo F
- Caprioli C
- Carlizza A
- Carnovali M
- Carrasco ExpĂłsito M
- Carrasco Mas A
- Carugati A
- Casarsa C
- Castellote Mc
- Castrodeza Sanz R
- Catalini R
- Cavazza S
- Cayman C
- Cazaubon M
- Cañas Alcåntara I
- Cenci C
- Ceresa F
- Cereto Castro F
- Chacko J
- Champion O
- Chandra D
- Chanut M
- Charters F
- Chevalet P
- Church A
- Ciampa A
- Ciarambino T
- Cillari E
- Cisneros de la Fuente E
- Clemente M
- Clements J
- Clifford P
- Cohen At
- Connault J
- Constans J
- Conti F
- Cordeanu M
- Cosmi B
- Couturaud F
- Cox D
- Crouch M
- Crowther M
- D'Alessandro A
- D'Angelo A
- D'Antoni S
- Davies E
- Davies M
- de Ancos Aracil C
- De Bartolomeo G
- De Campora P
- de Daborenea GonzĂĄlez Md
- De Dedker L
- De Franciscis S
- De Gaudenzi E
- de la Fuente Aguado J
- De La Fuente T
- de las Revillas Fa
- De Santis F
- De Tommaso I
- Decoulx E
- del Carmen FernĂĄndez-CapitĂĄn M
- del Toro Cervera J
- Delgado Bregel Jl
- Delpin S
- Demann C
- Demmig A
- Derrien B
- Di Francesco L
- Di Maggio R
- Di Micco P
- Di Michele D
- Di Minno G
- Di Nisio M
- Di Salvo M
- Diamand Jm
- Diard A
- Dimitri S
- Donadio F
- Douadi Y
- Drebes A
- Dres P
- Dupas S
- Durant C
- DĂez FernĂĄndez F
- DâAvino M
- Eberhad Rieker E
- Eberlein U
- Edhery S
- Eischer L
- Elias HernĂĄndez T
- Emter E
- Enea I
- Enger F
- Eschenburg J
- Eschenburg Ju
- Ewad H
- Fabbian F
- Falanga A
- Falvo N
- Farcas Taralunga C
- Felis S
- FernĂĄndez Iglesias A
- Ferrari E
- Ferri Bataler R
- Fiore V
- Fontanella A
- Forkmann L
- Franco E
- Frank J
- Frank U
- Franklin S
- Frausini G
- Freischmidt H
- Fritsche I
- Fronk Em
- Fuorlo M
- Gaillard C
- Gallerani M
- Gamberini S
- Garcia Ma
- GarcĂa GarcĂa Jm
- GarcĂa Loizaga A
- GarcĂa-Bragado Dalmau F
- Garrigues D
- Gassauer M
- George J
- Gerofke H
- Ghirarduzzi A
- Ghizzi G
- Gianniello F
- Gibbs C
- Gillet Jl
- Giordana P
- Girke F
- Gitt Ak
- Giudice G
- Goebels Mc
- Goh T
- GonzĂĄlez Porras Jr
- GonzĂĄlez Lg
- Grange C
- Grare F
- Grenot Mc
- GrĂŒn-Himmelmann K
- Guarnera G
- Guercini F
- Guggenbichler S
- Guil GarcĂa M
- Gupta S
- Gutierrez Ja
- Hadj Henni A
- Hartmann K
- Heilberger P
- Heinsius A
- Held M
- Herman G
- Hernando LĂłpez E
- Herold J
- Hertrich F
- Heuser S
- Hidden-Henic V
- Hirschl M
- Holmes J
- Holtea D
- Hommel H
- Hottin D
- HĂ€rtel D
- HĂŒtte G
- Imbert B
- Imberti D
- Iosub Di
- Iozzi E
- Irvine N
- Jackson-Voyzey E
- Jacquinandi V
- Jakob D
- Jara Palomares L
- Jaras Mj
- Jeanneret C
- Jiménez Castro D
- JimĂ©nez-RodrĂguez Madridejos R
- Jones N
- Joya Seijo D
- Jungandreas K
- Jurus C
- Jörg Gr
- Kalka C
- Kallat A
- Karcher J
- Karl-Wollweber S
- Keilhau Da
- Kerr P
- Kesteven P
- Kittel K
- Knittel M
- Knolinski T
- Kopplin U
- Kroschel U
- Kröger K
- KubicekâHofmann C
- Köhler C
- Körner I
- La Forgia S
- La Regina M
- Lacoste A
- Lacut K
- Laeis P
- Landolfi R
- Laroche Jp
- Lecumberri R
- Lench T
- Leschke M
- Lester W
- Lewis M
- LluĂs Padierna M
- Lodigiani C
- Lorenzo HernĂĄndez A
- Lowe G
- Lutz A
- LĂłpez Castellanos Gt
- López Jiménez L
- LĂłpez Gt
- LĂłpez-SĂĄez Jb
- LĂŒbbert G
- Madridano Cobo O
- Mainez Saiz C
- Mancuso G
- Manfredini R
- Manzano Espinosa L
- Marchena Yglesias Pj
- Marconi L
- Marcucci R
- Marencke Gh
- Margheriti R
- Marongiu S
- Marra A
- Marrocco F
- Martin M
- Martinelli I
- MartĂn del Pozo M
- MartĂnez N
- Masotti L
- Mazollier C
- McCormack T
- McCoye A
- McGrane F
- Mearelli F
- Mearns B
- Melibovsky L
- Mersel T
- Milesi V
- Millón Caño Ja
- Miserey G
- Mismetti P
- Modeliar Remond Ss
- Mommi V
- Monreal Bosch M
- Monreal M
- Montagna Es
- Monte Secades R
- Mora LujĂĄn Jm
- Moral Moral P
- Moreno Flores A
- Moriarty A
- Morretti T
- Morris W
- Mortensen K
- Mos L
- Moysidis T
- Mugno F
- Muñoz RodrĂguez Fj
- Narayanan M
- Nedey C
- Nelles H
- Nestler K
- Neumeister A
- Nieto RodrĂguez Ja
- Nitti C
- Nou M
- NĂșñez FernĂĄndez Mj
- Oettler W
- Olivieri O
- Oncala Sibajas E
- Onesta M
- Oo N
- Orlandini F
- Ortiz de Saracho J
- Ott I
- Otto A
- Ouvry P
- Pagliara V
- Paiella L
- Pala P
- Palasciano G
- Palla A
- Paoletti O
- Paolucci G
- Parisi R
- Parra Caballero P
- Pasca S
- Pasin M
- Pasligh M
- PatanĂš F
- Pedrajas Navas Jm
- Pennacchioni M
- Pepe C
- Pernod G
- Pertermann A
- Perticone F
- Peter Marschang P
- Peuch B
- Pfister R
- Piccinni Gc
- Pichot O
- Pierri F
- Piloquet Fx
- Pindur P
- Pinto A
- Piovella F
- Pivetti G
- Pizzini Am
- Placentino M
- Poli D
- Pons MartĂn del Campo I
- Porreca E
- Portillo SĂĄnchez J
- Poulain V
- Pourhassan S
- Predel D
- Prisco D
- Pudollek T
- PĂ©rez Rus G
- Quere I
- Quezada Loaiza A
- Quintavalla R
- Ramthor M
- Rancan E
- Ray P
- Reed M
- Reimer D
- Rennebaum C
- Reppel M
- Reynaldo P
- Ria L
- Richter R
- Rief P
- Riera Mestre A
- Rifai A
- Rivera Gallego A
- RodrĂguez BeltrĂĄn Em
- RoldĂĄn Schilling V
- Romero Pizarro Y
- Roncero LĂĄzaro A
- Rose P
- Rossetto V
- RothenbĂŒcher G
- Rothhagen B
- Rovinelli M
- Roy Pm
- Rubino P
- Rudolff S
- Ruiz J
- Rupoli S
- Russo V
- Saby Jc
- Saccullo G
- Sada S
- Saja K
- Sala G
- Salmi R
- Salvi A
- Samaden A
- San RomĂĄn TerĂĄn Cm
- Sangiuolo R
- Santalla Valle Ea
- Santini C
- Schafnitzl W
- Schellong S
- Schenone A
- Schiller M
- Schlosser A
- Schmeink P
- Schmeink T
- Schmidt J
- Schnabl S
- Schneider H
- Schnupp S
- Schulze M
- SchÀfer A
- Schön N
- Sciacqua A
- Sechtem U
- Sedl S
- Serra R
- Severino S
- Sevestre Ma
- Signorelli Ss
- Silvestri E
- Silvestris F
- Simon F
- Simonot-Lalandec E
- Siniscalchi V
- Siragusa S
- Sivakumaran M
- Sohal M
- Sollazzo V
- Solomons G
- Sonnenschein K
- Sorvillo S
- Stachowitz J
- Staub D
- Stephan D
- Stoshikj S
- Strafino C
- StĂŒcker M
- Sultanzadeh Sj
- Suriñach Caralt Jm
- SĂĄnchez Fuentes D
- Sånchez Muñoz-Torrero Jf
- SĂĄnchez Ălvarez J
- Talerico A
- Testa S
- Thachil J
- Thieme M
- Tiefenbacher C
- Tirado Miranda R
- Tissot A
- TodolĂ Parra Ja
- Tonello C
- Tosi F
- Tropeano P
- Tsantilas D
- Tufano A
- Usandizaga de Antonio E
- Vallarelli S
- Vaquero de Sedas M
- Venton T
- Verdecchia P
- Vetrano V
- Vieth P
- ViganĂČ S
- Villalta Blanch J
- Villalta S
- Villanueva Montes Ma
- Villaverde Ălvarez I
- Vincentelli Gm
- Violo C
- Vital-Durand D
- Vodoungnon H
- Voigts B
- vom Dahl J
- von Bilderling P
- von Maltik T
- Wakeling J
- Walby C
- Waldron M
- Watt S
- Weber H
- Weinmann S
- Weinrich K
- Werner N
- Werno Hs
- Werth S
- Weyer M
- Willcock W
- Willich Sn
- Wirtz P
- Wittig I
- Wittig K
- Wucherpfennig P
- Zafar A.
- Zanatta N
- Zierock P
- Zingaretti O
- Zorzi F
- zur Nieden T
- Publication venue
- 'Georg Thieme Verlag KG'
- Publication date
- 01/01/2017
- Field of study
Venous thromboembolism (VTE) is a significant cause of morbidity and mortality in Europe. Data from real-world registries are necessary, as clinical trials do not represent the full spectrum of VTE patients seen in clinical practice. We aimed to document the epidemiology, management and outcomes of VTE using data from a large, observational database. PREFER in VTE was an international, non-interventional disease registry conducted between January 2013 and July 2015 in primary and secondary care across seven European countries. Consecutive patients with acute VTE were documented and followed up over 12 months. PREFER in VTE included 3,455 patients with a mean age of 60.8 ± 17.0 years. Overall, 53.0 % were male. The majority of patients were assessed in the hospital setting as inpatients or outpatients (78.5 %). The diagnosis was deep-vein thrombosis (DVT) in 59.5 % and pulmonary embolism (PE) in 40.5 %. The most common comorbidities were the various types of cardiovascular disease (excluding hypertension; 45.5 %), hypertension (42.3 %) and dyslipidaemia (21.1 %). Following the index VTE, a large proportion of patients received initial therapy with heparin (73.2 %), almost half received a vitamin K antagonist (48.7 %) and nearly a quarter received a DOAC (24.5 %). Almost a quarter of all presentations were for recurrent VTE, with >80 % of previous episodes having occurred more than 12 months prior to baseline. In conclusion, PREFER in VTE has provided contemporary insights into VTE patients and their real-world management, including their baseline characteristics, risk factors, disease history, symptoms and signs, initial therapy and outcomes
A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)
- Author
- Abbott TE
- Abdallah RI
- Abdel-Aal IR
- Abdelmonem SA
- Abdo WF
- Abellan AN
- AbellĂĄn AN
- AbellĂĄn AN
- AbellĂĄn AN
- Abrams ST
- Ackerley C
- Acuña M
- Adda M
- Adhikari NK
- Adriano G
- Adrie C
- Affatato R
- Affatato R
- Afonso-Rivero D
- Agarossi A
- Agarwal LK
- Ageeva T
- Agrawal R
- Aguayo-DeHoyos E
- Aguilar AL
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguilar-Alonso E
- Aguirregabyria M
- Ahmadnia E
- Ahn C
- Ahn JY
- Ahn JY
- Ahn MY
- Ahn MY
- Aitken LM
- Akalaev R
- Akbarzadeh A
- Akcan-Arikan A
- Akhlagh SH
- Akhtar N
- AKI Research Group
- Akiduki N
- Akin S
- Akizuki N
- Akkoc T
- Ala-Kokko T
- Alanio A
- Albaiceta GM
- Albaladejo P
- Alberto F
- Albuisson E
- Alcala MA
- AlcĂĄzar L
- Aldabo-Pallas T
- Aldana NN
- Aldecoa C
- AlegrĂa L
- Alejandro R
- Alejo GC
- Alejos RM
- Alexandrova E
- Algarte R
- Algarte R
- Algieri I
- Algora-Weber A
- Alhamdi Y
- Aliaga FA
- Aliberti S
- Alkan A
- Almudena PM
- Almudevar PM
- Almudevar PM
- Almudévar PM
- Altıntas ND
- Alvarez J
- Alves SC
- Alzola LM
- Amargianitakis V
- Amaro R
- Amato MB
- Ambler M
- Amerongen MP
- Amininejad T
- Amor LL
- Amorim V
- Anand RK
- Andersen LW
- Andersson S
- Andoh K
- Andrade AH
- Andrade AH
- Andrade AH
- Andrade G
- Andreis DT
- Andreis DT
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- Anzueto A
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- ARIAM registry of adult cardiac surgery
- ARIAM-ANDALUCIA
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- Bianzina S
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- Calvo CP
- Calvo SA
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- Cambronero JA
- Cameron C
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- Campelo FA
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- Cannesson M
- CAPCRI Study
- Capellier G
- Carbonara M
- Cardellino S
- Cardenas CL
- Cariou A
- Cariou A
- Carlesso E
- Carmona AF
- Carmona SA
- Carmona SA
- Carmona SA
- Carmona SA
- Carone M
- Carpio D
- CarratalĂĄ A
- Carreira MM
- Carrero-GĂłmez F
- Carreño ER
- Carreño R
- Carvalho JP
- Carvalho KV
- Casals XN
- Casals XN
- Cassina T
- Castañeda DP
- Castellana D
- Castellanos A
- Castellanos A
- Castillo-Lorente E
- Castillo-Lorente E
- Catalan M
- CatalĂĄn RM
- Catena E
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- Cavalcanti D
- Cavalheiro AM
- Cavalier E
- Cavicchi FZ
- Cavicchi FZ
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- Champigneulle B
- Champigneulle B
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- Chang CH
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- Charron C
- Chatelon J
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- Chaussard M
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- Chelly J
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- Chen CM
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- Chen GQ
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- Chen YS
- Chen YS
- Chen YS
- Cheng CC
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- Cheng CC
- Cheng CC
- Cheng KC
- Cheng YJ
- Chernyshuk S
- Chevret S
- Chhor V
- Chiang CC
- Chiang CH
- Chiang CH
- Chiang CH
- Chiappa C
- Chiou KR
- Chiou KR
- Chiou KR
- Chiu LC
- Chiumello D
- Chiurazzi C
- Chiurazzi C
- Cho Y
- Cho YJ
- Cho YJ
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- Choi YJ
- Choi YY
- Chok L
- Cholkraisuwat J
- Cholley B
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- Chou W
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- Chouvarda I
- Christopher KB
- Chrétien JM
- Chrétien JM
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- Chumaev A
- Chung CR
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- Chytas A
- Cinel I
- Cinnella G
- Citerio G
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- Clemente EA
- Clermont G
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- Cohen Y
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- Colino L
- Collange O
- Colombo A
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- Combes A
- Concha P
- Connolly B
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- Contreras KM
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- Cook DJ
- Coombs M
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- Cordero M
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- Cordovilla-Guardia S
- CordĂłn J
- Corona A
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- Corte FD
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- Corzo L
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- Coss-Bu JA
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- Curiel-Balsera E
- Curinga M
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- Cuthbertson BH
- Cutuli SL
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- da Silva VZ
- Daga-Ruiz D
- Dalhuisen A
- Dalorzo M
- Damas P
- Dambrosio M
- DamÄs JK
- Das Neves A
- David H
- Davis C
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- Day A
- de Abreu MG
- De Backer A
- De Brito-Ashurst I
- De Cassai A
- De Freitas FF
- De Gasperi A
- de Hoyos EA
- De la Calle-Pedrosa N
- de la Fuente MV
- De La Fuente-Martos C
- De La Fuente-Martos C
- De La Rica AS
- De la Torre MA
- De Maglie M
- De Maglie M
- de Molina FJ
- De Morton N
- de Oca Sandoval MA
- De Pascale G
- De Rosa S
- De Sanctis F
- De Silva AP
- De Sousa I
- de Vera AP
- de Wilde W
- De Zani D
- Deblier I
- DeBrunnar R
- Del Arco A
- Del Moral OL
- Del Olmo R
- Del Rosario CG
- Del Sorbo L
- Delgado CP
- Delgado MJ
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- Demoule A
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- Descotte E
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- Di Gravio V
- Di Gregorio A
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- Dimitrov BD
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- Dimopoulou IK
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- Dougall PC
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- Durrant J
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- DĂŒnser MW
- E Silva ZC
- E YY
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- Echeverri JE
- EcheverrĂa JG
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- El Hossainy R
- El Sayed E
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- El Sayed I
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- Elbers PW
- Elgendy M
- Eliet J
- Emmanuel J
- Emmerich M
- Encina B
- Endacott R
- Endacott R
- Engelberts D
- ENVIN-HELICS Study Group
- Erb J
- Erdogan M
- Eroles AA
- Escalada SH
- Escalada SH
- Escoval A
- EscribĂĄ A
- EscĂłrcio S
- Eslami S
- Espinasse F
- Espinel E
- Estagnasie P
- Esteban A
- Estella A
- Estenssoro E
- Evelein-Brugman S
- Facchin F
- Faivre V
- Fang M
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- Farias P
- Faulds MC
- Fave G
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- Feijoo AM
- Feliot E
- Ferez MA
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- Fernandes N
- Fernandez NG
- Fernandez R
- Fernandez-Zamora MD
- FernĂĄndez IF
- FernĂĄndez L
- FernĂĄndez MV
- FernĂĄndez PA
- FernĂĄndez-Barat L
- Fernåndez-Mondéjar E
- FernĂĄndez-Ortega JF
- Ferraz AB
- Ferrero-Calleja J
- Ferri F
- Ferry A
- Ferré A
- FerrĂłn FR
- FerrĂłn FR
- Fiks T
- Fiks T
- FilekoviÄ S
- Filho CA
- Filho CA
- Filho CA
- Filipe E
- FINNRESUSCI Study Group
- Fischer G
- Fleischmann E
- Fless K
- Floccard B
- Flowers E
- Follin A
- Follin A
- Fong KY
- Fontaiña LP
- Fontana V
- Fontenot T
- Forel JM
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- Fournel E
- Fox B
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- Francioni JE
- Francioni JE
- Franco JF
- Frantzeskaki F
- Frantzeskaki F
- Frat JP
- Frat JP
- Frat JP
- Freile MT
- Frenzel T
- Frigeni B
- Frithiof R
- Fritz C
- FROG ICU Investigators
- Fromentin M
- Frontera PR
- Fuentes M
- Fumagalli F
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- Fumis RR
- Fushimi K
- GabĂĄn-DĂez Ă
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- Gaizauskas E
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- Galache JA
- Gallego-Corpa AI
- Gameiro J
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- Gandolfi S
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- Garcia IP
- Garcia IP
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- Garcia PK
- Garcia-Alvarez JM
- Garcia-Alvarez JM
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- GarcĂa MF
- GarcĂa-MartĂnez MV
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- Gasparovic V
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- Gavrychenko D
- Gayat E
- Geantot MA
- Gemmell L
- Gemmell LK
- Genc D
- GenĂšve C
- Georgopoulos D
- Geri G
- GETGAG Working Group
- GETGAG/SEMICYUC
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- Ghazal S
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- Ghosh S
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- Giannopoulos A
- Giesinger RE
- Gigorro RG
- Gil EM
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- Gimillo MR
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- Glogoski MZ
- Gobert F
- Godinho I
- Godoy K
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- Golovnya E
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- Gommers D
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- GonzĂĄlez AS
- GonzĂĄlez BS
- GonzĂĄlez JC
- Gonzålez-Jiménez AI
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- Goodwin S
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- Gouveia J
- Gracia RM
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- Grossestreuer A
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- Guidet B
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- Gutierrez LA
- Gutiérrez-Pizarraya A
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- HernĂĄndez A
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez AA
- HernĂĄndez G
- HernĂĄndez-Tejedor A
- Herpain A
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- Hualde JB
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- Huang WC
- Huang WC
- Huang WC
- Huang WC
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- Hung CY
- Hung WT
- Hung WT
- Hung WT
- Hung WT
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- Hutchings S
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- Hwang GS
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- Ignacio ML
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- Imanaka H
- Inaloo S
- Ince C
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- IPREA Study Group
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- Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group
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- Jayasinghe S
- Jean-Baptiste S
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- Jensen JU
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- JSEPTIC (Japanese Society of Education for Physicians and Trainees in Intensive Care) Clinical Trial Group
- Juan WC
- Juanas CA
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- Juez A
- Juliarena A
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- Junior JM
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- Kumbamu A
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- Olavarria E
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- Palencia E
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- Palomar M
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- Pereira UV
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- Pickkers P
- Picoita F
- PICS- HCPA: Programa Intrahospitalar de Combate Ă Sepse do Hospital de ClĂnicas de Porto Alegre
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- Plug Working Group
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- Preiser JC
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- Prowle JR
- PrÄ«dÄne S
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- Psarologakis C
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- Pugliese F
- Pujol LM
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- Rapid Diagnosis of Infections in the Critically Ill Team
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- ReVA Research Network and the PROVE Network Investigators
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- Santacruz C
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- Santana MC
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- Santiago AI
- Santiago AI
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- Scales DC
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- Shimony JS
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- Shin WJ
- Shinotsuka CR
- Shlyk I
- Shu CW
- Shuinotsuka C
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- Spadaro S
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- Spronk PE
- Spronk PE
- Sprung CL
- St Georgeâs University of London
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- Stubbs C
- Student Research Committee - Shiraz University of Medical Sciences
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- Suchomel P
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- Suh GJ
- Suh GJ
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- SĂĄez VC
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- SĂĄnchez MJ
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- SĂĄnchez PC
- SĂĄnchez PC
- SĂĄnchez-Elvira LA
- Tabatabaei HR
- Tabei SH
- Taccone F
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
- Taccone FS
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- Taggu A
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- Takaki S
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- Takeda M
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- Takei T
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- Tamura T
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- Tapponnier R
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- Tena SA
- Tencé N
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- Terzi N
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- Tjepkema-Cloostermans MC
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- Tofiño AL
- Toh CH
- Tokyo Womens Medical University
- Tomas E
- Tomas E
- Tomic I
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- Torner MM
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- Torrance HD
- Torrent RL
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- Tsukahara K
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- Urbanaviciute I
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- VallverdĂș I
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- Ălvarez JT
- Ălvarez-Lerma F
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Meeting abstrac
Approaches in biotechnological applications of natural polymers
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- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2016
- Field of study
Natural polymers, such as gums and mucilage, are biocompatible, cheap, easily available and non-toxic materials of native origin. These polymers are increasingly preferred over synthetic materials for industrial applications due to their intrinsic properties, as well as they are considered alternative sources of raw materials since they present characteristics of sustainability, biodegradability and biosafety. As definition, gums and mucilages are polysaccharides or complex carbohydrates consisting of one or more monosaccharides or their derivatives linked in bewildering variety of linkages and structures. Natural gums are considered polysaccharides naturally occurring in varieties of plant seeds and exudates, tree or shrub exudates, seaweed extracts, fungi, bacteria, and animal sources. Water-soluble gums, also known as hydrocolloids, are considered exudates and are pathological products; therefore, they do not form a part of cell wall. On the other hand, mucilages are part of cell and physiological products. It is important to highlight that gums represent the largest amounts of polymer materials derived from plants. Gums have enormously large and broad applications in both food and non-food industries, being commonly used as thickening, binding, emulsifying, suspending, stabilizing agents and matrices for drug release in pharmaceutical and cosmetic industries. In the food industry, their gelling properties and the ability to mold edible films and coatings are extensively studied. The use of gums depends on the intrinsic properties that they provide, often at costs below those of synthetic polymers. For upgrading the value of gums, they are being processed into various forms, including the most recent nanomaterials, for various biotechnological applications. Thus, the main natural polymers including galactomannans, cellulose, chitin, agar, carrageenan, alginate, cashew gum, pectin and starch, in addition to the current researches about them are reviewed in this article.. }To the Conselho Nacional de Desenvolvimento CientfĂico e TecnolĂłgico (CNPq) for fellowships (LCBBC and MGCC) and the Coordenação de Aperfeiçoamento de Pessoal de NvĂel Superior (CAPES) (PBSA). This study was supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UID/BIO/04469/2013 unit, the Project RECI/BBB-EBI/0179/2012 (FCOMP-01-0124-FEDER-027462) and COMPETE 2020 (POCI-01-0145-FEDER-006684) (JAT)
Molecular variability in Amerindians: widespread but uneven information
- Author
- ADAMS EJ
- ADAMS EJ
- AGOSTINI HT
- ANTĂNEZ-DE-MAYOLO G
- ARMOUR JAL
- ARNAIZ-VILLENA A
- ARRUDA VR
- AZOFEIFA J
- BAILLIET G
- BARLEY J
- BASSĂRES DS
- BATISTA O
- BATTILANA J
- BATZER MA
- BELICH MP
- BEVILAQUA LRM
- BIANCHI NO
- BIANCHI NO
- BIANCHI NO
- BLACK FL
- BLAGITKO N
- BOGDAWA HM
- BOISSINOT S
- BONATTO SL
- BONATTO SL
- BORTOLINI MC
- BORTOLINI MC
- BOWCOCK AM
- BRAVI CM
- BRAVI CM
- BRICENO I
- BROWN MD
- BUCHANAN AV
- BUROKER N
- CADAVID LF
- CALAFELL F
- CALAFELL F
- CARBONE MA
- CARVALHO-SILVA DR
- CASTAĂO AR
- CAVALLI-SFORZA LL
- CERNA M
- CHAKRABORTY R
- CHANG F-M
- CHEN JJ
- CHIBA AK
- CHOO SY
- COVAS DT
- CRAWFORD MH
- CREWS DE
- DE ANDRADE FM
- DE ANDRADE FM
- DEAN M
- DEKA R
- DEKA R
- DEKA R
- DEKA R
- DEKA R
- DEMARCHI DA
- DESTRO-BISTROL G
- DI RIENZO A
- DOMENA JD
- DORAN GH
- DORNELLES CL
- DUNCAN G
- EASTON RD
- ERLICH HA
- FAGUNDES NJR
- FERNĂNDEZ-VIĂA MA
- FORSTER P
- FRANCO RF
- FRANCO RF
- FRANCO RF
- FRĂGEAUX CJ
- FULLERTON SM
- GAEDIGK A
- GAMBOA R
- GARBER TL
- GASPAR PA
- GENĂ M
- GINTHER C
- GOLDMAN D
- GOMEZ-CASADO E
- GU X
- GUARINO FD
- GUERREIRO JF
- GUERREIRO JF
- GUĂDEZ YB
- GĂMEZ-CASADO E
- HAMMER MF
- HAMMER MF
- HAMMER MF
- HANDT O
- HARDING RM
- HARDY GH
- HAUSWIRTH WW
- HAUSWIRTH WW
- HEIDRICH EM
- HERRMANN B
- HERRMANN FH
- HIGUCHI R
- HILDEBRAND WH
- HILDEBRAND WH
- HORAI S
- HUOPONEN K
- HUTZ MH
- HUTZ MH
- HUTZ MH
- IMANISHI T
- IWANAGA KK
- JIN L
- JOBLING MA
- JOHNSON MJ
- JORGE LE
- JUUL L
- KARAFET T
- KARAFET T
- KARAFET TM
- KAUFMAN L
- KAUFMAN L
- KAYSER M
- KESSLER D
- KEYEUX G
- KIDD JR
- KIDD JR
- KIDD KK
- KITTLES RA
- KNIGHT A
- KOLMAN CJ
- KOLMAN CJ
- KOLMAN CJ
- KUNST CB
- KUWANO ST
- KVITKO K
- LALUEZA C
- LALUEZA C
- LALUEZA FOX C
- LALUEZA-FOX C
- LAYRISSE Z
- LAZARO AM
- LEBOUTE AP
- LELL JT
- LLEONART R
- LORENZ JG
- LUISELLI D
- MACK SJ
- MARCOS CY
- MARCOS CY
- MARIN GB
- MARTINEZ-LASO J
- MATEU E
- MATEU E
- MATHIAS N
- MATTEVI VS
- MATTEVI VS
- MCCOMB J
- MERCIER B
- MERRIWETHER DA
- MERRIWETHER DA
- MERRIWETHER DA
- MERRIWETHER DA
- MESA NR
- MEYER D
- MINGRONI-NETTO RC
- MITCHELL RJ
- MITCHELL RJ
- MITCHELL RJ
- MITCHELL RJ
- MIURA T
- MONSALVE MV
- MONSALVE MV
- MONSALVE MV
- MOURANT AE
- MOURANT AE
- MOURANT AE.
- MUĂOZ S
- NEEL JV
- NEEL JV.
- NEI M
- NOVICK GE
- O'ROURKE DH
- O'ROURKE DH
- OHTA T
- OHTA T
- OLIVEIRA SF.
- OLIVO A
- OLIVO-DĂAZ A
- OLSSON ML
- OSIER M
- PARHAM P
- PARHAM P
- PARR RL
- PENA SDJ
- PEPE G
- PEPE G
- PETERSON RJ
- PETZL-ERLER ML
- PETZL-ERLER ML.
- PĂĂBO S
- PĂĂBO S
- PĂĂBO S
- PĂĂBO S
- PĂREZ-LEZAUN A
- PĂREZ-LEZAUN A
- RAMON D
- RAMOS M
- RAMOS MD
- RANGEL-VILLALOBOS H
- RIBEIRO-DOS-SANTOS AKC
- RIBEIRO-DOS-SANTOS AKC
- RIBEIRO-DOS-SANTOS AKC
- RICKARDS O
- RIVAS F
- RODRIGUEZ-DELFIN L
- ROEWER L
- ROGAN PK
- ROGAN PK
- ROTHHAMMER F
- ROYCHOUDHURY AK
- RUIZ NARVAEZ EA
- RUIZ-LINARES A
- RUIZ-LINARES A
- RUPERT JL
- RUPERT JL
- RUPERT JL
- SALA A
- SALA A
- SALAMON H
- SALEMI M
- SALZANO FM
- SANTOS EJM
- SANTOS EJM
- SANTOS FR
- SANTOS FR
- SANTOS FR
- SANTOS FR
- SANTOS FR
- SANTOS FR
- SANTOS M
- SANTOS SEB
- SATTEN GA
- SCACCHI R
- SCHNEIDER JA
- SCOTT I
- SCOZZARI R
- SCOZZARI R
- SELVAKUMAR A
- SHEN P
- SHERRY ST
- SHIELDS GF
- SHIMIZU K
- SIMON D
- SMITH DG
- SOTOMAIOR VS
- STEPHENS JC
- STONE AC
- STONE AC
- STONE AC AND STONEKING M
- STONEKING M
- SU B
- SU B
- TARAZONA-SANTOS E
- THEILER GC
- THOMAS R
- TILLS D
- TISHKOFF SA
- TISHKOFF SA
- TISHKOFF SA
- TISHKOFF SA
- TITUS-TRACHTENBERG EA
- TORRONI A
- TORRONI A
- TORRONI A
- TRACHTENBERG EA
- TRACHTENBERG EA
- TRACHTENBERG EA
- UNDERHILL PA
- UNDERHILL PA
- URBANEK M
- VALDES AM
- VALLINOTO ACR
- VALLINOTO ACR
- VARGAS-ALARCĂN G
- VARGAS-ALARCĂN G
- VARGAS-ALARCĂN G
- VARGAS-ALARCĂN G
- VONA G
- VULLO CM
- WALL TL
- WALLACE DC
- WARD RH
- WARD RH
- WATKINS DI
- WEINBERG W
- YAGĂE J
- YAGĂE J
- YORK DS
- YUNIS JJ
- ZAGO MA
- ZERJAL T
- ZERJAL T
- ZHAO W
- ZHIVOTOVSKY LA
- ZIETKIEWICZ E
- ZIETKIEWICZ E
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-GĂłmez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- AntĂłn Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- AraĂșjo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- BarilĂ D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
- Bei R
- Bejarano E
- Bel S
- Belaid A
- Belgareh-Touzé N
- Bellarosa C
- Belleudi F
- Bello-Morales R
- BellĂł PĂ©rez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
- Boesze-Battaglia K
- Boeuf P
- Boland B
- Bomont P
- Bonaldo P
- Bonam SR
- Bonfili L
- Bonifacino JS
- Boone BA
- Bootman MD
- Bordi M
- Borner C
- Bornhauser BC
- Borthakur G
- Bosch J
- Bose S
- Botana LM
- Botas J
- Boulanger CM
- Boulton ME
- Bourdenx M
- Bourgeois B
- Bourke NM
- Bousquet G
- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
- Brand-Saberi B
- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
- Buch S
- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- BurĂłn MI
- Bustos V
- Butturini E
- Byrd A
- BĂĄnrĂ©ti Ă
- BĂŒttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
- Cai L
- Cai Q
- CairĂł M
- Calbet JA
- Caldwell GA
- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- CantĂ C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
- Carosi JM
- Carra S
- Carrier A
- Carrier L
- Carroll B
- Carter AB
- Carvalho AN
- Casanova M
- Casas C
- Casas J
- Cassioli C
- Castillo EF
- Castillo K
- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
- Chan ED
- Chan EYW
- Chan H
- Chan HH
- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- ChiurchiĂč V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- ColĂłn-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
- Diederich M
- Dieudé M
- Dikic I
- Ding S
- Ding W-X
- Dini L
- Dinic M
- DiniÄ J
- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
- Dong X
- Dong XC
- Dong Z
- Dorn Ii GW
- Dotsch V
- Dou H
- Dou J
- Dowaidar M
- Dridi S
- Drucker L
- du Toit A
- Du A
- Du C
- Du G
- Du H-N
- Du L-L
- Duan S-B
- Duan X
- Duarte SP
- Dubrovska A
- Dunlop EA
- Dupont N
- DurĂĄn RV
- Dwarakanath BS
- Dyshlovoy SA
- DĂĄvila VA
- DĂaz-Laviada I
- Ebrahimi-Fakhari D
- Eckhart L
- Edelstein CL
- Efferth T
- Eftekharpour E
- Eichinger L
- Eid N
- Eisenberg T
- Eissa NT
- Eissa S
- Ejarque M
- El Andaloussi A
- El-Hage N
- El-Naggar S
- El-Shafey ES
- Eleuteri AM
- Elgendy M
- Eliopoulos AG
- Elizalde MM
- Elks PM
- Elsasser H-P
- Elsherbiny ES
- Emerling BM
- Emre NCT
- Eng CH
- Engedal N
- Engelbrecht A-M
- Engelsen AST
- Enserink JM
- Escalante R
- Esclatine A
- Escobar-Henriques M
- Eskelinen E-L
- Espert L
- Eusebio M-O
- Fabrias G
- Fabrizi C
- Facchiano A
- Facchiano F
- Fadeel B
- Fader C
- Faesen AC
- Fairlie WD
- FalcĂł A
- Falkenburger BH
- Fan D
- Fan J
- Fan Y
- Fang EF
- Fang Y
- Fang Y
- Fanto M
- Farfel-Becker T
- Faure M
- Fazeli G
- Fedele AO
- Feldman AM
- Feng D
- Feng J
- Feng L
- Feng W
- Feng Y
- Feng Y
- Fenz Araujo T
- Ferguson TA
- Fernandez-Checa JC
- Fernie AR
- FernĂĄndez ĂF
- FernĂĄndez-Veledo S
- Ferrante AW
- Ferraresi A
- Ferrari MF
- Ferreira JCB
- Ferro-Novick S
- Figueras A
- Filadi R
- Filigheddu N
- Filippi-Chiela E
- Filomeni G
- Fimia GM
- Fineschi V
- Finetti F
- Finkbeiner S
- Fisher EA
- Fisher PB
- Flamigni F
- Fliesler SJ
- Flo TH
- Florance I
- Florey O
- Florio T
- Fodor E
- Follo C
- Fon EA
- Forlino A
- Fornai F
- Fortini P
- Fracassi A
- Fraldi A
- Franco B
- Franco R
- Franconi F
- Frankel LB
- Friedman SL
- Fröhlich LF
- FrĂŒhbeck G
- Fuentes JM
- Fujiki Y
- Fujita N
- Fujiwara Y
- Fukuda M
- Fulda S
- Furic L
- Furuya N
- Fusco C
- Gack MU
- Gaffke L
- Galadari S
- Galasso A
- Galindo MF
- Gallolu Kankanamalage S
- Galluzzi L
- Galy V
- Gammoh N
- Gan B
- Ganley IG
- Gao F
- Gao H
- Gao M
- Gao P
- Gao S-J
- Gao W
- Gao X
- Garcera A
- Garcia MN
- Garcia VE
- Garcia-Escudero V
- Garcia-Garcia A
- Garcia-Macia M
- Garcia-Ruiz C
- GarcĂa-Del Portillo F
- GarcĂa-Moreno D
- GarcĂa-Sanz P
- Garg AD
- Gargini R
- Garofalo T
- Garry RF
- Gassen NC
- Gatica D
- Ge L
- Ge W
- Geiss-Friedlander R
- Gelfi C
- Genschik P
- Gentle IE
- Gerbino V
- Gerhardt C
- Germain K
- Germain M
- Gewirtz DA
- Ghasemipour Afshar E
- Ghavami S
- Ghigo A
- Ghosh M
- Giamas G
- Giampietri C
- Giatromanolaki A
- Gibson GE
- Gibson SB
- Ginet V
- Giniger E
- Giorgi C
- Girao H
- Girardin SE
- Giridharan M
- Giuliano S
- Giulivi C
- Giuriato S
- Giustiniani J
- Gluschko A
- Goder V
- Goginashvili A
- Golab J
- Goldstone DC
- Golebiewska A
- Gomes LR
- Gomez R
- Gomez-Puerto MC
- Gomez-Sintes R
- Gong Q
- Goni FM
- Gonzalez-Hernandez T
- Gonzalez-Polo RA
- Gonzalez-Reyes JA
- GonzĂĄlez-Gallego J
- GonzĂĄlez-RodrĂguez P
- Goping IS
- Gorbatyuk MS
- Gorbunov NV
- Gorojod RM
- Gorski SM
- Goruppi S
- Gotor C
- Gottlieb RA
- Gozes I
- Gozuacik D
- Graef M
- Granatiero V
- Grasso D
- Gray JP
- Green DR
- Greenhough A
- Gregory SL
- Griffin EF
- Grinstaff MW
- Gros F
- Grose C
- Gross AS
- Gruber F
- Grumati P
- Grune T
- GrÀler MH
- Gu X
- Guan J-L
- Guardia CM
- Guda K
- Guerra F
- Guerri C
- Guha P
- Guillén C
- Gujar S
- Gukovskaya A
- Gukovsky I
- Gunst J
- Guntur AR
- Guo C
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- Guo H
- Guo L-W
- Guo M
- Gupta P
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- Gupta V
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- Gustafsson AB
- Gutterman DD
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- GĂŒnther A
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- Haapasalo A
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- Hanson PI
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- Harhaji-Trajkovic L
- Hariharan N
- Haroon N
- Harris J
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- Hasima Nagoor N
- Haspel JA
- Haucke V
- Hawkins WD
- Hay BA
- Haynes CM
- Hayrabedyan SB
- Hays TS
- HaÄ A
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- He Y-Y
- Heakal Y
- Heberle AM
- Hejtmancik JF
- Helgason GV
- Henkel V
- Herb M
- Hergovich A
- Herman-Antosiewicz A
- Hernandez C
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- Hernandez-Gea V
- HernĂĄndez A
- Herpin A
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- HervĂĄs JH
- Hesselson D
- Hetz C
- Heussler VT
- Higuchi Y
- Hilfiker S
- Hill JA
- Hlavacek WS
- Ho EA
- Ho IHT
- Ho PW-L
- Ho S-L
- Ho WY
- Hobbs GA
- Hochstrasser M
- Hoet PHM
- Hofius D
- Hofman P
- Holmberg CI
- Hombrebueno JR
- Hooper LV
- Hoppe T
- Horos R
- Hoshida Y
- Hsin I-L
- Hsu H-Y
- Hu B
- Hu D
- Hu L-F
- Hu MC
- Hu R
- Hu W
- Hu Y-C
- Hu Z-W
- Hua F
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- Hua Y
- Huan C
- Huang C
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- Huang C
- Huang H
- Huang K
- Huang MLH
- Huang R
- Huang S
- Huang T
- Huang X
- Huang YJ
- Huber TB
- Hubert V
- Hubner CA
- Hughes SM
- Hughes WE
- Humbert M
- Hummer G
- Hurley JH
- Hussain S
- Hussain S
- Hussey PJ
- Hutabarat M
- Hwang H-Y
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- Hyung-Ryong Kim
- Höhn A
- Ieni A
- Ikeda F
- Imagawa Y
- Imai Y
- Imbriano C
- Imoto M
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- Iovanna J
- Iozzo RV
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- Irazoqui JE
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- Ishikawa M
- Ishimwe N
- Isidoro C
- Ismail N
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- Itakura E
- Ito D
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- Ivanova S
- Iyer AKV
- Izquierdo JM
- Izumi M
- Jabir MS
- Jackson WT
- Jacobo-Herrera N
- Jacomin A-C
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- Jadiya P
- Jaeschke H
- Jagannath C
- Jakobi AJ
- Jakobsson J
- Janji B
- Jansen-DĂŒrr P
- Jansson PJ
- Jantsch J
- Januszewski S
- Jassey A
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- Jeltsch-David H
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- Jensen TE
- Jessen N
- Jewell JL
- Ji J
- Jia L
- Jia R
- Jiang L
- Jiang Q
- Jiang R
- Jiang T
- Jiang X
- Jiang Y
- Jimenez-Sanchez M
- Jin E-J
- Jin F
- Jin H
- Jin L
- Jin L
- Jin M
- Jin S
- Jo E-K
- Joffre C
- Johansen T
- Johnson GVW
- Johnston SA
- Jokitalo E
- Jolly MK
- Joosten LAB
- Jordan J
- Joseph B
- Ju D
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- Yen PM
- Yi C
- Yi-Ren Hong C-WH
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- Zang QS
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- Zhang X
- Zhang X
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- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
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- Zhao X-F
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- Zhong Q
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- Zhou Z-Y
- Zhu B
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- Zhu G-Q
- Zhu H
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- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
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- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
One thousand DNA barcodes of piranhas and pacus reveal geographic structure and unrecognised diversity in the Amazon
- Author
- A Machado-Allison
- A Machado-Allison
- A Riedel
- A Zarske
- A Zarske
- AG Muñoz
- AJ Drummond
- AL Cione
- AW Thompson
- B Lehner
- BC Carstens
- C Hoorn
- CH Eigenmann
- CQ Tang
- CT Philbrick
- D Ahrens
- D Darriba
- DL Rabosky
- E Pante
- E Paradis
- F Roxo
- G Talavera
- G Yu
- GS Lim
- HF JĂșlio JĂșnior
- I Sazima
- I Sazima
- IP Farias
- IP Farias
- J Bergsten
- J DĂaz
- J Pons
- J Sukumaran
- J Zhang
- JA Markert
- JM Padial
- JT Anderson
- K Katoh
- K Lohse
- KO Winemiller
- KO Winemiller
- KP Schliep
- LHG Pereira
- M JĂ©gu
- M JĂ©gu
- M JĂ©gu
- M Kearse
- M Malinsky
- M Mutanen
- M Pentinsaari
- M Pfenninger
- MC Andrade
- MC Andrade
- MC Andrade
- MC Andrade
- MCF Santos
- MD Escobar L.
- MH Sabaj PĂ©rez
- MJ Hickerson
- MT Monaghan
- MV Amado
- MY Stoeckle
- N Hubert
- N Hubert
- N Hubert
- NM Reid
- NTB Mateussi
- NV Ivanova
- OB Vitorino JĂșnior
- P Kapli
- RA Collins
- RD Ward
- RE Reis
- RE Reis
- RG Leite
- RP Ota
- SDJ Brown
- SE Miller
- T Fujisawa
- T Hrbek
- TNA Pereira
- U Saint-Paul
- WL Fink
- WL Fink
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Piranhas and pacus (Characiformes: Serrasalmidae) are a charismatic but understudied family of Neotropical fishes. Here, we analyse a DNA barcode dataset comprising 1,122 specimens, 69 species, 16 genera, 208 localities, and 34 major river drainages in order to make an inventory of diversity and to highlight taxa and biogeographic areas worthy of further sampling effort and conservation protection. Using four methods of species discovery - incorporating both tree and distance based techniques - we report between 76 and 99 species-like clusters, i.e. between 20% and 33% of a priori identified taxonomic species were represented by more than one mtDNA lineage. There was a high degree of congruence between clusters, with 60% supported by three or four methods. Pacus of the genus Myloplus exhibited the most intraspecific variation, with six of the 13 species sampled found to have multiple lineages. Conversely, piranhas of the Serrasalmus rhombeus group proved difficult to delimit with these methods due to genetic similarity and polyphyly. Overall, our results recognise substantially underestimated diversity in the serrasalmids, and emphasise the Guiana and Brazilian Shield rivers as biogeographically important areas with multiple cases of across-shield and within-shield diversifications. We additionally highlight the distinctiveness and complex phylogeographic history of rheophilic taxa in particular, and suggest multiple colonisations of these habitats by different serrasalmid lineages. © 2018 The Author(s)
Sequence analysis of European maize inbred line F2 provides new insights into molecular and chromosomal characteristics of presence/absence variants
- Author
- A Abyzov
- A BelĂł
- A DĂaz
- A Knoll
- AA Golicz
- AJ Sharp
- Alain Charcosset
- AM Phillippy
- AP Dempster
- Aude Darracq
- Aurélie Bérard
- B McClintock
- C Hirsch
- C Trapnell
- C Vitte
- C Vitte
- CC Chang
- Clémentine Vitte
- CN Hirsch
- CĂ©line Chevalier
- D Kim
- D Marie
- DC Koboldt
- DE Cook
- EG Bakker
- ES Buckler
- F Lu
- F Marroni
- FA SimĂŁo
- G Lunter
- G Parra
- GG Faust
- H Fu
- H Li
- J Lai
- J Messing
- J Shen
- J-M Chia
- J-T Brandenburg
- Jean-Philippe Pichon
- Johann Joets
- Jorge Duarte
- JT Simpson
- K Chen
- K Ye
- L Camus-Kulandaivelu
- L Feuk
- LG Maron
- LK McHale
- M Boetzer
- M Boetzer
- M Martin
- M McVey
- M Morgante
- M Muñoz-AmatriaĂn
- Marie-Christine Le Paslier
- MC Schatz
- MD Yandeau-Nelson
- MI Tenaillon
- MR Woodhouse
- MW Ganal
- ND Young
- NM Springer
- P Jones
- P SanMiguel
- P Stankiewicz
- Peter Rogowsky
- PS Schnable
- Q Wang
- R Schmieder
- R Schmieder
- RA Swanson-Wagner
- RC Iskow
- RK Saxena
- S Brunner
- S Kurtz
- S LĂȘ
- SSM Adawy
- Stéphane Nicolas
- T MagoÄ
- T Mary-Huard
- T Winzer
- TP Robbins
- Tristan Mary-Huard
- VM GonzĂĄlez
- W Bao
- WL Brown
- X Gan
- X Xu
- Y Jiao
- Z Zhang
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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