41,990 research outputs found
A note on the predictions of models with modular flavor symmetries
Models with modular flavor symmetries have been thought to be highly predictive. We point out that these predictions are subject to corrections from non–holomorphic terms in the Lagrangean. Specifically, in the models discussed in the literature, the Kähler potential is not fixed by the symmetries, for instance. The most general Kähler potential consistent with the symmetries of the model contains additional terms with additional parameters, which reduce the predictive power of these constructions. We also comment on potential ways of how one may conceivably retain the predictivity
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Intraspinal pressure and spinal cord perfusion pressure predict neurological outcome after traumatic spinal cord injury
Compact printed ultra-wideband antenna: corrugated monopole augmented with parasitic strips
© 2016 Informa UK Limited, trading as Taylor & Francis Group. A novel compact microstrip line-fed ultra-wideband (UWB) antenna is reported in this paper. The antenna consists of a corrugated half-ellipse monopole and three strips that act as near-field resonant parasitic (NFRP) elements. The entire UWB band (3.1–10.6 GHz) is covered from a very compact size: 19 mm × 10 mm. Two of the NFRP strips are utilized to cover more effectively the lower portion of the UWB frequency range; the third one improves the broadside gain values by 3.28 dB in the upper portion. As a consequence, this compact design maintains a stable radiation performance over the entire UWB band
Prototype construction of a compiler for network analysis feasibility study
Feasibility of unified compilers for network analysi
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Visibility graph analysis of intraspinal pressure signal predicts functional outcome in spinal cord injured patients.
To guide management of patients with acute spinal cord injuries, we developed intraspinal pressure monitoring from the injury site. Here, we examine the complex fluctuations in the intraspinal pressure signal using network theory. We analyzed 7,097 hours of intraspinal pressure data from 58 patients with severe cord injuries. Intraspinal pressure signals were split into hourly windows. Each window was mapped into a visibility graph as follows: Vertical bars were drawn at 0.1 Hz representing signal amplitudes. Each bar produced a node, thus totalling 360 nodes per graph. Two nodes were linked with an edge if the straight line through the nodes did not intersect a bar. We computed several topological metrics for each graph including diameter, modularity, eccentricity and small-worldness. Patients were followed up for 20 months on average. Our data show that the topological structure of intraspinal pressure visibility graphs is highly sensitive to pathological events at the injury site including cord compression (high intraspinal pressure), ischemia (low spinal cord perfusion pressure) and deranged autoregulation (high spinal pressure reactivity index). These pathological changes correlate with long graph diameter, high modularity, high eccentricity and reduced small-worldness. In a multivariate logistic regression model, age, neurological status on admission and average node eccentricity were independent predictors of neurological improvement. We conclude that analysis of intraspinal pressure fluctuations after spinal cord injury as graphs, rather than time series, captures clinically important information. Our novel technique may be applied to other signals recorded from injured CNS e.g intracranial pressure, tissue metabolite and oxygen levels
Effects of local hypothermia-rewarming on physiology, metabolism and inflammation of acutely injured human spinal cord.
In five patients with acute, severe thoracic traumatic spinal cord injuries (TSCIs), American spinal injuries association Impairment Scale (AIS) grades A-C, we induced cord hypothermia (33 °C) then rewarming (37 °C). A pressure probe and a microdialysis catheter were placed intradurally at the injury site to monitor intraspinal pressure (ISP), spinal cord perfusion pressure (SCPP), tissue metabolism and inflammation. Cord hypothermia-rewarming, applied to awake patients, did not cause discomfort or neurological deterioration. Cooling did not affect cord physiology (ISP, SCPP), but markedly altered cord metabolism (increased glucose, lactate, lactate/pyruvate ratio (LPR), glutamate; decreased glycerol) and markedly reduced cord inflammation (reduced IL1β, IL8, MCP, MIP1α, MIP1β). Compared with pre-cooling baseline, rewarming was associated with significantly worse cord physiology (increased ICP, decreased SCPP), cord metabolism (increased lactate, LPR; decreased glucose, glycerol) and cord inflammation (increased IL1β, IL8, IL4, IL10, MCP, MIP1α). The study was terminated because three patients developed delayed wound infections. At 18-months, two patients improved and three stayed the same. We conclude that, after TSCI, hypothermia is potentially beneficial by reducing cord inflammation, though after rewarming these benefits are lost due to increases in cord swelling, ischemia and inflammation. We thus urge caution when using hypothermia-rewarming therapeutically in TSCI
Quantum Lightning Never Strikes the Same State Twice
Public key quantum money can be seen as a version of the quantum no-cloning
theorem that holds even when the quantum states can be verified by the
adversary. In this work, investigate quantum lightning, a formalization of
"collision-free quantum money" defined by Lutomirski et al. [ICS'10], where
no-cloning holds even when the adversary herself generates the quantum state to
be cloned. We then study quantum money and quantum lightning, showing the
following results:
- We demonstrate the usefulness of quantum lightning by showing several
potential applications, such as generating random strings with a proof of
entropy, to completely decentralized cryptocurrency without a block-chain,
where transactions is instant and local.
- We give win-win results for quantum money/lightning, showing that either
signatures/hash functions/commitment schemes meet very strong recently proposed
notions of security, or they yield quantum money or lightning.
- We construct quantum lightning under the assumed multi-collision resistance
of random degree-2 systems of polynomials.
- We show that instantiating the quantum money scheme of Aaronson and
Christiano [STOC'12] with indistinguishability obfuscation that is secure
against quantum computers yields a secure quantum money schem
Europium-doped calcium pyrophosphates : allotropic forms and photoluminescent properties
In a search for new luminescent biological probes, we synthesized calcium pyrophosphates doped with europium up to an atomic Eu/(Eu+Ca) ratio of 2%. They were prepared by coprecipitating a mixture of calcium and europium salts with phosphate. After heating at 900°C in air, two phases coexisted, identified as the β calcium pyrophosphate form and EuPO4. Heating near 1250°C in air, during the β→ transformation, europium ions substitute for calcium ions in the * calcium pyrophosphate structure as demonstrated by the spectroscopic study. Europium ions with both valence states (divalent and trivalent) were observed in the samples. Following the synthesis procedure, partial reduction of Eu3+ took place even in an oxidizing atmosphere. The 0.5%-doped compound could serve as a sensitive probe in biological applications. Depending on the excitation wavelength, the luminescence occurs either in the red or in the blue regions, which discriminates it from parasitic signals arising from other dyes or organelles in live cells
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