97 research outputs found
Position-momentum local realism violation of the Hardy type
We show that it is, in principle, possible to perform local realism violating
experiments of the Hardy type in which only position and momentum measurements
are made on two particles emanating from a common source. In the optical
domain, homodyne detection of the in-phase and out-of-phase amplitude
components of an electromagnetic field is analogous to position and momentum
measurement. Hence, local realism violations of the Hardy type are possible in
optical systems employing only homodyne detection.Comment: 10 pages, no figures, to be published in Physical Review
Eosinophils downregulate lung alloimmunity by decreasing TCR signal transduction
Despite the accepted notion that granulocytes play a universally destructive role in organ and tissue grafts, it has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. The mechanism of eosinophil-mediated tolerance, or their role in regulating alloimmune responses in the absence of immunosuppression, remains unknown. Using lung transplants in a fully MHC-mismatched BALB/c (H2d) to C57BL/6 (H2b) strain combination, we demonstrate that eosinophils downregulate T cell-mediated immune responses and play a tolerogenic role even in the absence of immunosuppression. We further show that such downregulation depends on PD-L1/PD-1-mediated synapse formation between eosinophils and T cells. We also demonstrate that eosinophils suppress T lymphocyte responses through the inhibition of T cell receptor/CD3 (TCR/CD3) subunit association and signal transduction in an inducible NOS-dependent manner. Increasing local eosinophil concentration, through administration of intratracheal eotaxin and IL-5, can ameliorate alloimmune responses in the lung allograft. Thus, our data indicate that eosinophil mobilization may be utilized as a novel means of lung allograft-specific immunosuppression
Nine-valent HPV vaccine efficacy against related diseases and definitive therapy:comparison with historic placebo population
Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes
Diasporic Encounters, Sacred Journeys: Ritual, Normativity and the Religious Imagination Among International Asian Migrant Women
This issue highlights recent ethnographic work that discloses migrant womenâs creative engagements with the people and landscapes in the places they migrate to. We challenge a dominant view that construes women international migrants from Asia as docile bodies shaped and constrained by their transnational (re)productive labours. And we reject simplistic contemporary formulations of transnational migration that posit a singular, homogeneous âtransnational social fieldâ. Three key processes, relatively ignored and under theorised are interrogated: diaspora formation, ritual performance and changing normativities. A focus on diaspora encourages us to move beyond a political and economic analysis to consider cultural practices, continuities and discontinuities in migrantsâ relationships with the people and places they travel to, as well as those left behind. A focus on ritual emphasises the significance of religious performance in the making of place and convivial sociality. A focus on normativity foregrounds the ways that peopleâs affective relationships are performatively reworked and transgressed within and across discrepant diasporic spaces
From West Indies to East Indies: Archipelagic Interchanges
In this paper, I work to rethink notions of comparison and area studies by viewing my ethnographic work in Indonesia through the lens of theories developed by anthropologists working in the Caribbean region. In bringing 'East Indies' and 'West Indies' together in this way, I explore the possibility of reconfigured networks of citation, collaboration and interchange that might help anthropology respond in new ways to contemporary dynamics of globalisation. © 2006 Copyright Discipline of Anthropology and Sociology, The University of Western Australia
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