2,068 research outputs found

    THE EVALUATION AND IMPACT OF COLIFORM BACTERIAL AND ENTERIC VIRUS POLLUTION IN SOUTHEASTERN NEW HAMPSHIRE

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    Predicting carcinogenicity by using batteries of dependent short-term tests.

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    Among the various methods for predicting carcinogenicity from a battery of short-term tests (STTs), the carcinogenicity prediction and battery selection (CPBS) procedure is the most prominent. A major assumption of CPBS is that the STTs used in the prediction are conditionally independent. Results of recent National Toxicology Program studies of four commonly used in vitro STTs contradict this assumption, thereby necessitating modification of CPBS to accommodate dependencies. This is accomplished via log-linear modeling, which then also yields an important dividend: standard errors for the predicted probabilities of carcinogenicity

    Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa by electroporation: Correction

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    Two mistakes in our article on gene replacement by gene targeting at the his-3 locus (Margolin, B.S. et al., 1997, FGN 44:34-36) have come to our attention

    Improved plasmids for gene targeting at the his-3 locus of Neurospora crassa by electroporation

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    We report two new plasmids, pBM60 and pBM61, and procedures to efficiently generate single- copy transformants targeted to the his-3 locus in Neurospora crassa
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