9,432 research outputs found

    Monte Carlo simulations of single polymer force-extension relations

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    We present Monte Carlo simulations for studying the statistical mechanics of arbitrarily long single molecules under stretching. In many cases in which the thermodynamic limit is not satisfied, different statistical ensembles yield different macroscopic force-displacement curves. In this work we provide a description of the Monte Carlo simulations and discuss in details the assumptions adopted

    Cost effectiveness analysis of laparoscopic hysterectomy compared with standard hysterectomy: results from a randomised trial

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    Objective: To assess the cost effectiveness of laparoscopic hysterectomy compared with conventional hysterectomy (abdominal or vaginal). Design: Cost effectiveness analysis based on two parallel trials: laparoscopic (n = 324) compared with vaginal hysterectomy (n = 163); and laparoscopic (n = 573) compared with abdominal hysterectomy (n = 286). Participants: 1346 women requiring a hysterectomy for reasons other than malignancy. Main outcome measure: One year costs estimated from NHS perspective. Health outcomes expressed in terms of QALYs based on women's responses to the EQ-5D at baseline and at three points during up to 52 weeks' follow up. Results: Laparoscopic hysterectomy cost an average of pound401 (708;C571)more(95708; C571) more (95% confidence interval pound271 to pound542) than vaginal hysterectomy but produced little difference in mean QALYs (0.0015, 0.0 15 to 0.0 18). Mean differences in cost and QALYs generated an incremental cost per QALY gained of pound267 333 (471789; E380 437). The, probability that laparoscopic hysterectomy is cost effective was below 50% for a large range of values of willingness to pay for an additional QALY. Laparoscopic hysterectomy cost an average of pound186 (328;E265)morethanabdominalhysterectomy,although95328; E265) more than abdominal hysterectomy, although 95% confidence intervals crossed zero -pound26 to pound375); there was little difference in mean QALYs (0.007, - 0.008 to 0,023), resulting in an incremental cost per QALY gained of pound26 571 (46 893; E37 813). If the NHS is willing to pay pound30 0 00 for an additional QALY, the probability that laparoscopic hysterectomy is cost effective is 56%. Conclusions: Laparoscopic hysterectomy is not cost effective relative to vaginal hysterectomy. Its cost effectiveness relative to the abdominal procedure is finely balanced

    Critical chain length and superconductivity emergence in oxygen-equalized pairs of YBa2Cu3O6.30

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    The oxygen-order dependent emergence of superconductivity in YBa2Cu3O6+x is studied, for the first time in a comparative way, on pair samples having the same oxygen content and thermal history, but different Cu(1)Ox chain arrangements deriving from their intercalated and deintercalated nature. Structural and electronic non-equivalence of pairs samples is detected in the critical region and found to be related, on microscopic scale, to a different average chain length, which, on being experimentally determined by nuclear quadrupole resonance (NQR), sheds new light on the concept of critical chain length for hole doping efficiency.Comment: 7 RevTex pages, 2 Postscript figures. Submitted to Phys. Rev.

    Hydrogeology of the Sabatini Volcanic District (Central Italy)

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    This paper supports the 'Hydrogeological map of the Sabatini Volcanic District'. The map provides an overview of the hydrogeological setting of the Sabatini Volcanic District, using experimental water level data integrated with former volcanological and hydrogeological studies. The 1:50,000 scale map was produced in order to provide support to local authorities and professionals working on groundwater management. Fifteen hydrogeological complexes were defined based on volcanological properties and hydrogeological conditions

    Epitaxial growth and thermodynamic stability of SrIrO3/SrTiO3 heterostructures

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    Obtaining high-quality thin films of 5d transition metal oxides is essential to explore the exotic semimetallic and topological phases predicted to arise from the combination of strong electron correlations and spin-orbit coupling. Here, we show that the transport properties of SrIrO3 thin films, grown by pulsed laser deposition, can be optimized by considering the effect of laser-induced modification of the SrIrO3 target surface. We further demonstrate that bare SrIrO3 thin films are subject to degradation in air and are highly sensitive to lithographic processing. A crystalline SrTiO3 cap layer deposited in-situ is effective in preserving the film quality, allowing us to measure metallic transport behavior in films with thicknesses down to 4 unit cells. In addition, the SrTiO3 encapsulation enables the fabrication of devices such as Hall bars without altering the film properties, allowing precise (magneto)transport measurements on micro- and nanoscale devices.Comment: 5 pages, 3 figure

    A Numerical Analysis on Nanofluid Mixed Convection in Triangular Cross-Sectioned Ducts Heated by a Uniform Heat Flux:

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    In this paper, results obtained by the numerical investigation on laminar mixed convection in triangular ducts, filled with nanofluids, are presented in order to evaluate the fluid dynamic and thermal features of the considered geometry by considering Al 2 O 3 /water based nanofluids. The system is heated by a constant and uniform heat flux also along the perimeter of the triangular duct section in H2 mode as thermal boundary condition and the single-phase model has been assigned for a Reynolds number value equal to 100. Results are given for different nanoparticle volume concentrations and Richardson number values ranging from 0% to 5% and from 0 to 5, respectively. Results, presented for the fully developed regime flow, show the enhancement of average convective heat transfer coefficients values for increasing values of Richardson number and particle fractions. However, wall shear stress and required pumping power profiles increase as expected. The PEC analysis showed that the use of nanofluids in mixed convection seems slightly convenient. It should be underlined that, at the moment, experimental data are not available to compare the numerical proposed model for mixed convection in horizontal triangular ducts with nanofluids

    The effect of school design on users' responses: A systematic review (2008-2017)

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    This systematic review focused on the effect of the educational environment design on students and teachers performance, satisfaction, and wellbeing. Starting from a bulk of 1307 articles, a set of N = 68 empirical papers was selected and organized on the basis of four different content clusters, i.e., architectural building design and aesthetic features, indoor environmental features, classroom design, and school green spaces/outdoor spaces. From the analysis of research findings, the key role of pleasant, warm, and flexible learning environments emerged, for promoting both wellbeing and performance of users. More specifically, the presence of charming colors and pictures, ergonomic furniture, and adequate acoustic, thermal comfort, ventilation, and natural lighting have emerged as important features that school designers should care for. Furthermore, an integration of both indoor and outdoor learning situations showed to be effective for improving students learning and wellbeing
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