Sustainable development program at the Faculty of Nautical Studies of Barcelona, Nautical engineering education

Nautical engineering education institutions play an important role and are a key tool in the future sustainable maritime transport and naval world. This paper addresses the role of nautical engineering education in the learning and implementation of the competence of sustainability and social commitment (SSC) in the Nautical Faculty of Barcelona and presents results of the first year of the implementation of the environmental program STEP2015 at the Universitat Politècnica de Catalunya.Postprint (published version

Frailty level prediction in older age using hand grip strength functions over time

This version of the article has been accepted for publication, after peer review and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/978-3-030-85099-9_29.Frailty syndrome can be defined as a clinical state in which there is a rise in individual vulnerability, developing an increase in both the dependence of the person and mortality. Frailty is completely related to age. A fundamental factor to apply rehabilitative interventions successfully resides in having a simple and reliable method capable of identifying frailty syndrome. Frailty indexes (FI) have several sources of uncertainty trough the opinion of the patients, white coat effect and external factors. Moreover, in the clinical practice, the experience of the geriatricians led them to determine an approximation of the frailty level only with a simple handshake. Hand grip strength (HGS) has been widely used in tests by investigators and therapists to be able to diagnose sarcopenia and frailty, as it is a reliable indicator of the overall muscle strength, which decreases with age. Most researches focused mainly on peak HGS, which will not give insight on how the patient’s strength was distributed over time. In the present work it is proposed to evaluate HGS behavior over a period of time, and to develop a system based on Machine Learning for the identification of frailty levels using physiological features, FI and the classical signal processing based on statistics of the HGS signals. The starting hypothesis is that it can be identified the “way” of performing HGS correlated with the level of frailty. To achieve this goal a clinical study was designed and carried out with a cohort of 70 elderly persons, in two Hospitals.This work was partially supported by the Spanish Ministry of Ciencia, Innovación y Universidades under project RTI2018-096701-B-C22, and by the Catalonia FEDER program, resolution GAH/815/2018 under the project, PECT Garraf : Envelliment actiu i saludable i dependència.Peer ReviewedPostprint (author's final draft

Sustainable development program at the Faculty of Nautical Studies of Barcelona, Nautical engineering education

Nautical engineering education institutions play an important role and are a key tool in the future sustainable maritime transport and naval world. This paper addresses the role of nautical engineering education in the learning and implementation of the competence of sustainability and social commitment (SSC) in the Nautical Faculty of Barcelona and presents results of the first year of the implementation of the environmental program STEP2015 at the Universitat Politècnica de Catalunya

Ordago a la pista

Producció: Irene Blay ; Productor ejecutiu: Lucas Martínez; Idea original: Pep Gili; fotografia: Luis S. Martínez ; banda sonora: Tomás Peire; intèrprets: Manel Solàs, Joan Mallofré, German Torme, Manel Tricas

Neoplasias uroteliais papilíferas superficiais da bexiga (pTa e pT1): correlação da expressão do p53, KI-67 E CK20 com grau histológico, recidiva e progressão tumoral

OBJETIVO: Investigar a expressão imunoistoquímica dos marcadores p53, Ki-67, CK20 em neoplasias uroteliais papilíferas superficiais da bexiga e correlacionar com o grau histológico, progressão tumoral e recidiva. MÉTODOS: Foram selecionadas amostras de 43 pacientes portadores de carcinoma de células transicionais superficiais da bexiga. Elas foram distribuídas em dois grupos, um denominado recorrente, de 18 indivíduos e outro não recorrente, com 25 casos. Foram confeccionados blocos multiamostrais. A técnica imunoistoquímica empregada foi de imunoperoxidase e os anticorpos foram: p53 (clone DO7), o Ki-67 (clone SP6) e CK20. RESULTADOS: A expressão do p53 foi observada em 11 casos, todos tumores de alto grau (p=0,0001). A progressão histológica ocorreu em seis indivíduos (p=0,0076). Dos 18 casos recorrentes, seis apresentaram imunorreação para o p53 e 12 foram negativos para este anticorpo (p=0,1715). O Ki-67 foi positivo em 17 dos 18 casos do grupo recorrente (p=0,0001) e dos 20 tumores de alto grau, 18 apresentaram reação para este anticorpo (p=0,0001). Dos 18 indivíduos que tiveram recorrência, 13 apresentaram expressão anômala para CK20 (p=0,0166). Nos carcinomas de alto grau, dos 20 casos, 16 apresentaram expressão anômala para este anticorpo, enquanto que 18 dos 23 indivíduos com tumores de baixo grau mostraram expressão habitual para a CK20 (p=0,0002). CONCLUSÃO: O p53 mostrou boa correlação com a progressão histológica e grau histológico. O Ki-67 apresentou forte associação com a recidiva e grau histológico, e a CK20 também associou-se com estas variáveis