Medico-Legal Aspects of the Electroencephalogram

Brain injuries are difficult to prove and the lawyer must use all demonstrative evidence available to him to make the jury aware of the injury to his client. The electroencephalogram, though it has only been used as a diagnostic tool and as demonstrative evidence for the last fifteen to twenty years, is becoming more important in this field. It is becoming a more exact science and, it is believed, will be used more widely in the future. There does not appear to be any great problem of admissibility where they are properly identified, performed by competent technicians, using adequate equipment, and which accurately represent the information they are intended to reveal. If they serve the cause of justice and are relevant and material to the medical issues to be determined, courts everywhere will admit them for tha tpurpose

Medico-Legal Aspects of the Electroencephalogram

Brain injuries are difficult to prove and the lawyer must use all demonstrative evidence available to him to make the jury aware of the injury to his client. The electroencephalogram, though it has only been used as a diagnostic tool and as demonstrative evidence for the last fifteen to twenty years, is becoming more important in this field. It is becoming a more exact science and, it is believed, will be used more widely in the future. There does not appear to be any great problem of admissibility where they are properly identified, performed by competent technicians, using adequate equipment, and which accurately represent the information they are intended to reveal. If they serve the cause of justice and are relevant and material to the medical issues to be determined, courts everywhere will admit them for tha tpurpose

AKUNTABILITAS DAN TRANSPARANSI BERBASIS BAGI HASIL (ANALISIS TERHADAP KARyAwAN ToKo DI KoTA BEUREUNUEN)

Research  on  Accountability  and  Transparency  Based  on  the  results  of  this study aims to determine the implementation of Accountability and Transpar- ency Based Revenue in Beureunuen City Store. Some Stores in Beureunuen City implement a profit-sharing system with employees. The study was conducted from March 2016 to February 2017. This research uses qualitative approach. For Collection - to get information about employeesvalidation techniques done by digging information from some informants directly related to the Business. In addition, researchers also con- ducted direct observation at the location of the study to verify the data wheth- er the data obtained from the informant in line with the reality of the field or not. The result of the research analysis shows that the application of Account- ability and Transparency Based on Profit is good. However, there is a weakness in terms of the absence of annual balance sheet. For that researchers offer Bal- ance Sheet report. The implementation of Profit-Based Accountability and Transparency is already well categorized in terms of responsibility to the trustee, providing information to employees and granting the employee rights in accordance with the earn- ings of the company’s profit within one year of Hijriah

Enhanced aging properties of HKUST-1 in hydrophobic mixed-matrix membranes for ammonia adsorption.

Metal-organic frameworks (MOFs) in their free powder form have exhibited superior capacities for many gases when compared to other materials, due to their tailorable functionality and high surface areas. Specifically, the MOF HKUST-1 binds small Lewis bases, such as ammonia, with its coordinatively unsaturated copper sites. We describe here the use of HKUST-1 in mixed-matrix membranes (MMMs) prepared from polyvinylidene difluoride (PVDF) for the removal of ammonia gas. These MMMs exhibit ammonia capacities similar to their hypothetical capacities based on the weight percent of HKUST-1 in each MMM. HKUST-1 in its powder form is unstable toward humid conditions; however, upon exposure to humid environments for prolonged periods of time, the HKUST-1 MMMs exhibit outstanding structural stability, and maintain their ammonia capacity. Overall, this study has achieved all of the critical and combined elements for real-world applications of MOFs: high MOF loadings, fully accessible MOF surfaces, enhanced MOF stabilization, recyclability, mechanical stability, and processability. This study is a critical step in advancing MOFs to a stable, usable, and enabling technology

Adsorption Humidity Effects, Microparticle Rate Behavior, and Thermal Swing Adsorption

Application of adsorption processes for air purification requires an approach, which accounts for the presence of humidity. Four separate but related studies are conducted to examine the adsorption processes. A new pure component adsorption isotherm is developed to describe Type 5 adsorption. The results are used to correlate data of water on activated carbon. This model derives from the concept that capillary condensation accounts for Type 5 behavior and is strongly dependent on the pore size distribution. The new model has the advantage over all other prior models of being invertible in terms of loading and partial pressure. The Henry's law limit and heat of adsorption effects are discussed. A study of coadsorption of water and immiscible organics is also presented. Data for the system chloroethane water on two activated carbons is measured. A new coadsorption model is developed to describe immiscible vapors and water. This model has the advantage of at most one adjustable parameter and can also be solved without iteration. Good agreement is demonstrated between this new model, data measured here and literature data. The use of thermal swing adsorption for air purification is examined in this work. An experimental system is used to perform cycling experiments under dry and humid conditions. A dynamic simulation model is developed to describe several of cycling runs. Using the coadsorption model developed above the good agreement is found between the data and simulation profiles. Optimization of cycle parameters was investigated to show that some moderation of the feed water content is required to obtain high purification of a light vapor challenge at ambient temperature conditions. The internal rate effects of commercial adsorbents have been reported in the literature. There is seldom an attempt to review the many approaches. Data was measured using a gravimetric technique for chloroethane and hexane on BPL activated carbon and 13X molecular sieve. A distributed parameter micropore diffusion model was solved to simulate this data. Regression of the adsorption and desorption data was used to determined micropore diffusion coefficients. These values were shown to compare well with literature values

Impact of prior hospital mortality versus surgical volume on mortality following surgery for congenital heart disease

ObjectiveOur objective was to assess the relationships of a hospital’s past adjusted in-hospital mortality and surgical volume with future in-hospital mortality after surgery for congenital heart disease.MethodsUsing the Pediatric Health Information Systems database, we (1) calculated hospital surgical volume and standardized mortality ratio (= observed number of deaths/expected number of deaths adjusted for surgery type) for January 2004 through June 2006 for children (0-18 years) after surgery for congenital heart disease at 38 hospitals and (2) assessed the relationship between these values and subsequent mortality during July 2006 through December 2008. We constructed Poisson regression models to estimate risk of mortality, adjusting for age, race, sex, genetic syndrome, insurance type, and surgery type (using the Risk Adjustment in Congenital Heart Surgery method).ResultsThere were 49,792 hospital encounters during 2004 through 2008 for pediatric patients having surgery for congenital heart disease, with an overall in-hospital mortality of 3.45%. For the 24,112 eligible encounters during July 2006 through December 2008, a hospital’s prior standardized mortality ratio was significantly associated with postoperative in-hospital mortality (P < .0001), and a hospital’s prior surgical volume had only borderline significance (P = .0792). On stratified analysis, past standardized mortality ratio was associated with mortality for both lower- and higher-risk surgical risk categories (P = .0105 and .0015, respectively). Hospital surgical volume was not significantly associated with mortality for lower-risk categories (P = .4122), but it was borderline significant for higher-risk categories (P = .0678).ConclusionsIn this data set, prior hospital surgical volume tended to be associated with improved mortality after higher-risk operations in pediatric patients with congenital heart disease, whereas prior hospital postoperative mortality was significantly associated with mortality across all risk strata of congenital heart surgery

UTILIZATION OF FUNCTIONALIZED CATANIONIC SURFACTANT VESICLES TO INVESTIGATE PROTEIN-GLYCAN INTERACTIONS

Despite the estimate that more than half of the human proteome is glycosylated, the field of glycomics lags substantially behind proteomics and genomics. The ubiquity of carbohydrates in and on the cell is directly related to the extensive roles they play in the folding and stabilization of protein structure, and in cellular recognition processes. The slow progress in deciphering glycan interactions at a molecular level is in large part due to the absence of a functional system to express, on a large scale, carbohydrates of known structure, in the context of a biologically relevant assay system. The goals of my research are to prepare and characterize glycan-functionalized catanionic surfactant vesicles as a platform for glycan synthesis, and to demonstrate that the resulting glycan-functionalized vesicles serve as a scaffold for the interrogation of protein-glycan interactions. To accomplish this goal, a high-yield method for the purification of N. gonorrhoeae lipooligosaccharide (LOS) glycosyltransferase LgtE, an enzyme that catalyzes the addition of galactose onto a terminal glucose found on LOS, was first optimized. Preliminary evidence is presented, suggesting that catanionic vesicles solubilize macromolecules found in inclusion bodies, indicating that surfactant vesicles facilitate the purification of insoluble species. A novel method exploiting differential lectin binding, measured by flow cytometry, was developed to demonstrate LgtE activity on whole cell bacteria and on catanionic vesicles functionalized with LOS or a synthetic glycolipid acceptor substrate. The data from these studies confirm the vesicles' robustness in the highly sensitive assay, and demonstrates LgtE mediated oligosaccharide biosynthesis on vesicles, regardless of acceptor origin. Enzyme activity was then characterized on whole cells and LOS functionalized vesicles. Unexpectedly, LgtE is observed to have approximately the same affinity for both terminal glucose and galactose as acceptor substrates for galactosyl transfer. Finally, enzymatic synthesis and retention of the vesicles by hydrophobically modified chitosan coated electrodes is demonstrated by differential antibody binding. This dissertation presents proof-of-concept that glycan-functionalized catanionic vesicles can be used to create a high-specificity and high-throughput glycan array. This array will allow for the investigation of a variety of protein-glycan interactions, and will undoubtedly have applications in many fields of glycomics