Seismic characterization of fluid migration and Pockmarks formation in the Estremadura Spur, Western Iberian Margin

: A field with more than 30 pockmarks was recently discovered in the Estremadura Spur outer shelf (Lourinhã Monocline). The processing of high-resolution seismic lines permitted the characterization of this pockmark field and of the seismic sequence of the Plio-Quaternary basin where they occur. Results show that this region has been affected by several episodes of fluid migration and fluid escape during the Plio-Quaternary, expressed by the presence of the pockmarks that at the present-time seem to be mainly inactive

Perception of sleep duration in adult patients with suspected obstructive sleep apnea

PURPOSE: Discrepancies between subjective and objective measures of total sleep time (TST) are frequent among insomnia patients, but this issue remains scarcely investigated in obstructive sleep apnea (OSA). We aimed to evaluate if sleep perception is affected by the severity of OSA. METHODS: We performed a 3-month cross-sectional study of Brazilian adults undergoing overnight polysomnography (PSG). TST was objectively assessed from PSG and by a self-reported questionnaire (subjective measurement). Sleep perception index (SPI) was defined by the ratio of subjective and objective values. Diagnosis of OSA was based on an apnea/hypopnea index (AHI) ≥ 5.0/h, being its severity classified according to AHI thresholds: 5.0-14.9/h (mild OSA), 15.0-29.9/h (moderate OSA), and ≥ 30.0/h (severe OSA). RESULTS: Overall, 727 patients were included (58.0% males). A significant difference was found in SPI between non-OSA and OSA groups (p = 0.014). Mean SPI values significantly decreased as the OSA severity increased: without OSA (100.1 ± 40.9%), mild OSA (95.1 ± 24.6%), moderate OSA (93.5 ± 25.2%), and severe OSA (90.6 ± 28.2%), p = 0.036. Using logistic regression, increasing SPI was associated with a reduction in the likelihood of presenting any OSA (p = 0.018), moderate/severe OSA (p = 0.019), and severe OSA (p = 0.028). However, insomnia was not considered as an independent variable for the presence of any OSA, moderate/severe OSA, and severe OSA (all p-values > 0.05). CONCLUSION: In a clinical referral cohort, SPI significantly decreases with increasing OSA severity, but is not modified by the presence of insomnia symptoms.publishersversionpublishe

Fluid escape structures in the Gulf of Cadiz. Evidence of structural control from combined seismic reflection and sidescan sonar interpretation

The Gulf of Cadiz is situated in a tectonically complex and active region, close to a major plate boundary. The tectonic regime in the area is characterized by a combination of important strike-slip movement and compressional tectonics related to the Africa-Eurasia NW-directed convergence, responsible for the formation of the Gibraltar Arc. Extensive mud volcanism, pockmarks, mud diapirism and carbonate chimneys related to hydrocarbon rich fluid venting are observed throughout the area. There is an extensive coverage of seismic reflection profiles in the area that includes industry data, a few deep-multichannel lines (IAM, ARRIFANO and BIGSETS) and many single-channel lines (both Sparker and Airgun data). During the TTR-12 (July/2002) and the GAP (Nov-Dec/2003) cruises, several single and multi channel seismic lines were acquired in this area that complement the existing database collected during previous TTR Cruises. These lines have re-processed to enhance the deeper structure.A combined interpretation of the available side-scan sonar imaging obtained by the Naval Research Laboratory in 1992 and the available seismic lines (both single channel and multichannel) shows clear evidence of the structural control of the mud volcanism in the study area. In particular, it appears that some of the mud volcanoes are located at the intersection between NW-SE strike-slip faults and thrusts of variable orientation, reflecting the curvature of the Gibraltar Arc

Development, validation and comparative study with no-apnea, STOP-bang, and NoSAS

Background: Obstructive sleep apnea (OSA) is a very prevalent disorder. Here, we aimed to develop and validate a practical questionnaire with yes-or-no answers, and to compare its performance with other well-validated instruments: No-Apnea, STOP-Bang, and NoSAS. Methods: A cross-sectional study containing consecutively selected sleep-lab subjects underwent full polysomnography. A 4-item model, named GOAL questionnaire (gender, obesity, age, and loud snoring), was developed and subsequently validated, with item-scoring of 0–4 points (≥2 points indicating high risk for OSA). Discrimination was assessed by area under the curve (AUC), while predictive parameters were calculated using contingency tables. OSA severity was classified based on conventionally accepted apnea/hypopnea index thresholds: ≥5.0/h (OSA≥5), ≥15.0/h (OSA≥15), and ≥30.0/h (OSA≥30). Results: Overall, 7377 adults were grouped into two large and independent cohorts: derivation (n = 3771) and validation (n = 3606). In the derivation cohort, screening of OSA≥5, OSA≥15, and OSA≥30 revealed that GOAL questionnaire achieved sensitivity ranging from 83.3% to 94.0% and specificity ranging from 62.4% to 38.5%. In the validation cohort, screening of OSA≥5, OSA≥15, and OSA≥30, corroborated validation steps with sensitivity ranging from 83.7% to 94.2% and specificity from 63.4% to 37.7%. In both cohorts, discriminatory ability of GOAL questionnaire for screening of OSA≥5, OSA≥15, and OSA≥30 was similar to No-Apnea, STOP-Bang or NoSAS. Conclusion: All four instruments had similar performance, leading to a possible greater practical implementation of the GOAL questionnaire, a simple instrument with only four parameters easily obtained during clinical evaluation.publishersversionpublishe

Relative sit-to-stand power: aging trajectories, functionally relevant cut-off points, and normative data in a large European cohort

Background: A validated, standardized, and feasible test to assess muscle power in older adults has recently been reported: the sit-to-stand (STS) muscle power test. This investigation aimed to assess the relationship between relative STS power and age and to provide normative data, cut-off points, and minimal clinically important differences (MCID) for STS power measures in older women and men. Methods: A total of 9320 older adults (6161 women and 3159 men) aged 60–103 years and 586 young and middle-aged adults (318 women and 268 men) aged 20–60 years were included in this cross-sectional study. Relative (normalized to body mass), allometric (normalized to height squared), and specific (normalized to legs muscle mass) muscle power values were assessed by the 30 s STS power test. Body composition was evaluated by dual energy X-ray absorptiometry and bioelectrical impedance analysis, and legs skeletal muscle index (SMI; normalized to height squared) was calculated. Habitual and maximal gait speed, timed up-and-go test, and 6 min walking distance were collected as physical performance measures, and participants were classified into two groups: well-functioning and mobility-limited older adults. Results: Relative STS power was found to decrease between 30–50 years (-0.05 W·kg-1·year-1; P > 0.05), 50–80 years (-0.10 to -0.13 W·kg-1·year-1; P < 0.001), and above 80 years (-0.07 to -0.08 W·kg-1·year-1; P < 0.001). A total of 1129 older women (18%) and 510 older men (16%) presented mobility limitations. Mobility-limited older adults were older and exhibited lower relative, allometric, and specific power; higher body mass index (BMI) and legs SMI (both only in women); and lower legs SMI (only in men) than their well-functioning counterparts (all P < 0.05). Normative data and cut-off points for relative, allometric, and specific STS power and for BMI and legs SMI were reported. Low relative STS power occurred below 2.1 W·kg-1 in women (area under the curve, AUC, [95% confidence interval, CI] = 0.85 [0.84–0.87]) and below 2.6 W·kg-1 in men (AUC [95% CI] = 0.89 [0.87–0.91]). The age-adjusted odds ratios [95% CI] for mobility limitations in older women and men with low relative STS power were 10.6 [9.0–12.6] and 14.1 [10.9–18.2], respectively. MCID values for relative STS power were 0.33 W·kg-1 in women and 0.42 W·kg-1 in men. Conclusions: Relative STS power decreased significantly after the age of 50 years and was negatively and strongly associated with mobility limitations. Our study provides normative data, functionally relevant cut-off points, and MCID values for STS power for their use in daily clinical practice. © 2021 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders

TOPOGRAFIA DO CONE MEDULAR EM UM GATO MOURISCO, Herpailurus yagouaroundi (Severtzow, 1858)(FELIDAE)

A anestesia caudal foi proposta pela primeira vez em 1926 e diversas técnicas foram desenvolvidas para anestesiar os nervos espinhais lombares e sacrais. Os métodos para anestesia epidural exigem conhecimento da anatomia da região envolvida. O objetivo deste estudo foi determinar a topografia do cone medular do gato mourisco, tornando possível a realização desta técnica anestésica em um felino silvestre de nossa fauna. Uma gata mourisca, adulta, proveniente do Zoológico Parque do Sabiá, Uberlândia-MG, foi encaminhado ao Laboratório de Pesquisa em Animais Silvestres (LAPAS), com o objetivo de determinar a topografia do cone medular para tornar possível a realização desta técnica anestésica em um felino silvestre de nossa fauna. Este animal foi fixado em solução de formol a 10%. Feita incisão de pele, os músculos da coluna vertebral foram retirados, os arcos vertebrais foram seccionados para visualização da medula espinhal e seus envoltórios. O cone medular neste animal iniciou-se na sexta vértebra lombar (L6) e terminou na segunda vértebra sacral (S2), com comprimento total de 50mm. O comprimento corporal deste felino foi de 473mm. Conclui-se que o melhor local para a anestesia epidural do membro pélvico no gato mourisco está entre as vértebras L6 e S2. Topographycal study on the medullar cone in jaguarundi, Herpailurus yagouaroundi (Severtzow,1858)(FELIDAE Abstract Since the caudal anesthesia was first proposed in 1926 many techniques were developed to anesthethize the lumbar and sacral nerves. Such methods for epidural anesthesia require knowledge of the relative anatomical regions. The objetive of the present study was to determine the topographic anatomy of the jaguarundi medullar cone as a morphological basis for application of anesthesis techniques. One adult female jaguarondi that perished by natural death has been obtained form the Sabiá Zoo Park, Uberlândia, MG, Brazil and conducted to tha Wild Animals Laboratory. The animal was fixes in 10% formalin solution. Following skin incision, muscles of the vertebral column were removed and the vertebral arcs sectioned for the visualization of hte spinal cord and its wrappers. Epidural anesthesic drug in the medullar cone. The medullar cone in this jaguarundi startet in the sixth lumbar vertebra (L6) and ended in the second sacral vertebra (S2); the spinal cord length was 50mm. The corporal length of this feline measured 473mm. The best region to perform the pelvic anesthesia in a jaguarundi is between the vertebra L6 and S2

Embryonic dormancy in seeds of Bactris gasipaes Kunth (peach-palm)

Bactris gasipaes is a domesticated palm whose fruits are of great importance for the Amazonian people and whose heart of palm is also receiving economic interest in other brazilian and Latin America regions. The aim of this study was verify embryonic dormancy and its correlation with first cataphyll emergence in B. gasipaes seeds collected from four plants at Manaus city and four others at Coari city, both in the Amazonas state, Brazil. After extraction and cleaning, some of the seeds (4 replications of 25 per plant) were sown in a seedbed with a sawdust and sand mixture as substrate, and embryos (4 replications of 10 per plant), after extraction, were inoculated into half strength Murashige and Skoog cultures. Were used 100 seeds and 40 embryo per treatment. Whole seed and embryo germination varied between the different source plants and locations, with the greatest difference observed for the emergence of first cataphyll from seeds in the seedbed. For the most part of variables, results of seed and embryo were positively associated, namely, as one went up the other also, and vice versa. These results suggesting that, at least in part, seed dormancy in Bactris gasipaes is associated with embryonic dormancy. © 2017, Associacao Brasileira de Tecnologia de Sementes. All rights reserved