669 research outputs found

    Second Documented Record Of The Rufous-fronted Antthrush, Formicarius Rufifrons (aves: Formicariidae), In Brazil

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    We present the second documented record of the Rufous-fronted Antthrush Formicarius rufifrons Blake, 1957 in Brazil. The record was made in Ramal do Riozinho do Rola, 45 km north of Rio Branco municipality, Acre state. The recordings were deposited in the archives of Xeno-canto and Wikiaves. Our record represents a distribution extension of 247 km northeast of the closest known location. © 2016 Check List and Authors.12

    The Na+/glucose cotransporters: from genes to therapy

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    Glucose enters eukaryotic cells via two types of membrane-associated carrier proteins, the Na+/glucose cotransporters (SGLT) and the facilitative glucose transporters (GLUT). The SGLT family consists of six members. Among them, the SGLT1 and SGLT2 proteins, encoded by the solute carrier genes SLC5A1 and SLC5A2, respectively, are believed to be the most important ones and have been extensively explored in studies focusing on glucose fluxes under both physiological and pathological conditions. This review considers the regulation of the expression of the SGLT promoted by protein kinases and transcription factors, as well as the alterations determined by diets of different compositions and by pathologies such as diabetes. It also considers congenital defects of sugar metabolism caused by aberrant expression of the SGLT1 in glucose-galactose malabsorption and the SGLT2 in familial renal glycosuria. Finally, it covers some pharmacological compounds that are being currently studied focusing on the interest of controlling glycemia by antagonizing SGLT in renal and intestinal tissues

    Transitioning Adolescents Living With Hiv/aids To Adult-oriented Health Care: An Emerging Challenge

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    Objective: To review the literature on transition from pediatric to adult-oriented health care and discuss this issue in the specific context of chronic conditions. Sources: MEDLINE and LILACS were searched for relevant English and French-language articles published between 1990 and 2010. Summary of the findings: The transition of adolescents with chronic diseases from pediatric care to adult-oriented services has been a growing concern among pediatric specialties. In recent years, young people living with HIV/AIDS have begun to reach adulthood, giving rise to several challenges. The studies reviewed herein discuss such relevant topics as: the difference between transfer, an isolated event, and transition, a gradual process; the transition models used in different services; the importance of transitioning in a planned and individualized manner; the need for comprehensive interaction between pediatric and adult-oriented care teams; the importance of joint participation of adolescents, their families, and health professionals in the process; barriers to and factors that promote successful transitions; and the special needs of adolescents with HIV/AIDS in this important period of life. Conclusions: Several authors agree that transitioning adolescents to adult-oriented health care should be a gradual process not determined by age alone. It requires a plan established with ample dialogue among adolescents, their families, and pediatric and adult care teams. However, there is little evidence to support any specific model of health care transition. This should prompt researchers to conduct more prospective studies on the theme, especially in more vulnerable groups such as adolescents living with HIV/AIDS. Copyright © 2010 by Sociedade Brasileira de Pediatria.866465472Brown, L.K., Lourie, K.J., Maryland, P., Children and adolescents living with HIV and AIDS: A review (2000) Journal of Child Psychology and Psychiatry and Allied Disciplines, 41 (1), pp. 81-96. , DOI 10.1017/S0021963099004977Gortmaker, S.L., Hughes, M., Cervia, J., Brady, M., Johnson, G.M., Seage III, G.R., Song, L.Y., Oleske, J.M., Effect of combination therapy including protease inhibitors on mortality among children and adolescents infected with HIV-1 (2001) New England Journal of Medicine, 345 (21), pp. 1522-1528. , DOI 10.1056/NEJMoa011157Matida, L.H., Marcopito, L.F., O aumento do tempo de sobrevida das crianças com AIDS - Brasil (2002) Boletim Epidemiológico AIDS, 15 (1), pp. 49-55Candiani, T.M., Pinto, J., Cardoso, C.A., Carvalho, I.R., Dias, A.C., Carneiro, M., Impact of highly active antiretroviral therapy (HAART) on the incidence of opportunistic infections, hospitalizations and mortality among children and adolescents living with HIV/AIDS in Belo Horizonte, Minas Gerais State, Brazil (2007) Cad Saude Publica, 23 (SUPPL. 3), pp. S414-23Miller, T., The next decade: Cardiovascular risks, outcomes, prevention, and treatment in pediatric HIV infection (2010) J Pediatr, 86, pp. 3-5. , Rio J(2008) Boletim Epidemiológico - AIDS e DST. Ano V - no 1 - 27a - 52a - Semanas Epidemiológicas - Julho a Dezembro de 2007. Ano V - No 1-01a - 26a - Semanas Epidemiológicas - Janeiro a Junho de 2008, , Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde - Programa Nacional de DST e Aids. Brasília: Ministério da SaúdeLandau, L.I., Cystic fibrosis: Transition from pediatric to adult physician's care (1995) Thorax, 50, pp. 1031-1032Scal, P., Blum, R.W., Transition for youth with chronic conditions: Primary care physicians' approaches (2002) Pediatrics, 110 (6 II), pp. 1315-1321Shaw, K.L., Southwood, T.R., McDonagh, J.E., User perspectives of transitional care for adolescents with juvenile idiopathic arthritis (2004) Rheumatology, 43, pp. 770-778. , British Paediatric Rheumatology Group. OxfordMcDonagh, J.E., Shaw, K.L., Southwood, T.R., Growing up and moving on in rheumatology: Development and preliminary evaluation of a transitional care programme for a multicentre cohort of adolescents with juvenile idiopathic arthritis (2006) J Child Health Care, 10, pp. 22-42Aberastury, A., Knobel, M., (2000) Adolescência Normal - Um Enfoque Psicanalítico, , Porto Alegre: ArtmedMeleis, A.I., Sawyer, L.M., Im, E.O., Hilfinger Messias, D.K., Schumacher, K., Experiencing transitions: An emerging middle-range theory (2000) ANS Adv Nurs Sci, 23, pp. 12-28Kralik, D., Visentin, K., Van Loon, A., Transition: A literature review (2006) J Adv Nurs, 55, pp. 320-329Rosen, D.S., Blum, R.W., Britto, M., Sawyer, S.M., Siegel, D.M., Transition to adult health care for adolescents and young adults with chronic conditions: Position paper of the Society for Adolescent Medicine (2003) J Adolesc Health, 33, pp. 309-311. , Society for Adolescent Medicine(2009) The World Bank Data & Statistics, , http://go.worldbank.org/K2CKM78CC0, Country ClassificationAccess: 03/01/2010Bell, L.E., Sawyer, S.M., Transition of care to adult services for pediatric solid-organ transplant recipients (2010) Pediatr Clin North Am, 57, pp. 593-610Kipps, S., Bahu, T., Ong, K., Ackland, F.M., Brown, R.S., Fox, C.T., Griffin, N.K., Dunger, D.B., Current methods of transfer of young people with Type 1 diabetes to adult services (2002) Diabetic Medicine, 19 (8), pp. 649-654. , DOI 10.1046/j.1464-5491.2002.00757.xLotstein, D.S., McPherson, M., Strickland, B., Newacheck, P.W., Transition planning for youth with special health care needs: Results from the national survey of children with special health care needs (2005) Pediatrics, 115 (6), pp. 1562-1568. , http://pediatrics.aappublications.org/cgi/reprint/115/6/1562, DOI 10.1542/peds.2004-1262Blum, R.W., Garell, D., Hodgman, C.H., Jorissen, T.W., Okinow, N.A., Orr, D.P., Slap, G.B., Transition from child-centered to adult health-care systems for adolescents with chronic conditions: A position paper of the Society for Adolescent Medicine (1993) Journal of Adolescent Health, 14 (7), pp. 570-576. , DOI 10.1016/1054-139X(93)90143-DSawyer, S.M., Blair, S., Bowes, G., Chronic illness in adolescents: Transfer or transition to adult services? (1997) J Paediatr Child Health, 33, pp. 88-90Forbes, A., While, A., Ullman, R., Lewis, S., Mathes, L., Griffiths, P., (2002) A Multimethod Review to Identify Components of Practice Which May Promote Continuity in the Transition from Child to Adult Care for Young People with Chronic Illness or Disability, , London: NCCSDOBoyle, M.P., Farukhi, Z., Nosky, M.L., Strategies for improving transition to adult cystic fibrosis care, based on patient and parent views (2001) Pediatric Pulmonology, 32 (6), pp. 428-436. , DOI 10.1002/ppul.1154Abdale, B., Kuhl, K., Tullis, D.E., Evaluation of patient satisfaction with the transition from a pediatric hospital to an adult centre (1994) Pediatr Pulmonol, 18 (SUPPL. 10), pp. 291-292Betz, C.L., Adolescent transitions: A nursing concern (1998) Pediatr Nurs, 24, pp. 23-28Dommergues, J.P., Alvin, P., Transition from pediatric to adult care in severe chronic diseases (2003) Archives de Pediatrie, 10 (4), pp. 295-299. , DOI 10.1016/S0929-693X(03)00041-1David, T.J., Transition from the paediatric clinic to the adult service (2001) Journal of the Royal Society of Medicine, 94 (8), pp. 373-374Geenen, S.J., Powers, L.E., Sells, W., Understanding the role of health care providers during the transition of adolescents with disabilities and special health care needs (2003) Journal of Adolescent Health, 32 (3), pp. 225-233. , DOI 10.1016/S1054-139X(02)00396-8, PII S1054139X02003968Tucker, L.B., Cabral, D.A., Transition of the Adolescent Patient with Rheumatic Disease: Issues to Consider (2007) Rheumatic Disease Clinics of North America, 33 (3), pp. 661-672. , DOI 10.1016/j.rdc.2007.07.005, PII S0889857X07000415, Pediatric RheumatologyFreed, G.L., Hudson, E.J., Transitioning children with chronic diseases to adult care: Current knowledge, practices, and directions (2006) Journal of Pediatrics, 148 (6), pp. 824-827. , DOI 10.1016/j.jpeds.2006.02.010, PII S0022347606001089Remorino, R., Taylor, J., Smoothing things over: The transition from pediatric to adult care for kidney transplant recipients (2006) Progress in Transplantation, 16 (4), pp. 303-308McCurdy, C., DiCenso, A., Boblin, S., Ludwin, D., Bryant-Lukosius, D., Bosompra, K., There to here: Young adult patients' perceptions of the process of transition from pediatric to adult transplant care (2006) Progress in Transplantation, 16 (4), pp. 309-316Reiss, J.G., Gibson, R.W., Walker, L.R., Health care transition: Youth, family, and provider perspectives (2005) Pediatrics, 115 (1), pp. 112-120. , http://pediatrics.aappublications.org/cgi/reprint/115/1/112, DOI 10.1542/peds.2004-1321Alpay, H., Transition of the adolescent patient to the adult clinic (2009) Perit Dial Int, 29 (SUPPL. 2), pp. S180-2Weissberg-Benchell, J., Wolpert, H., Anderson, B.J., Transitioning from pediatric to adult care: A new approach to the post-adolescent young person with type 1 diabetes (2007) Diabetes Care, 30 (10), pp. 2441-2446. , http://care.diabetesjournals.org/cgi/reprint/30/10/2441, DOI 10.2337/dc07-1249Arnett, J.J., Emerging adulthood. A theory of development from the late teens through the twenties (2000) Am Psychol, 55, pp. 469-480Arnett, J.J., (2004) Emerging Adulthood: The Winding Road from the Late Teens Through the Twenties, , New York: Oxford University PressWojciechowski, E.A., Hurtig, A., Dorn, L., A natural history study of adolescents and young adults with sickle cell disease as they transfer to adult care: A need for case management services (2002) Journal of Pediatric Nursing, 17 (1), pp. 18-27. , DOI 10.1053/jpdn.2002.30930Hauser, E.S., Dorn, L., Transitioning adolescents with sickle cell disease to adult-centered care (1999) Pediatr Nurs, 25, pp. 479-488Viner, R., Transition from paediatric to adult care. Bridging the gaps or passing the buck? (1999) Arch Dis Child, 81, pp. 271-275(2007) Lost in Transition: Moving Young People between Child and Adult Health Services, , Royal College of Nursing. London: RCNLewis-Gary, M.D., Transitioning to adult health care facilities for young adults with a chronic condition (2001) Pediatr Nurs, 27, pp. 521-524(2006) Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection, , The Working Group on Antiretroviral Therapy and Medical Management of HIV-Infected Children. Bethesda, MD: Department of Health and Human Services(2009) Programa Nacional de DST e Aids. Recomendações para Terapia Antirretroviral Em Crianças e Adolescentes Infectados Pelo HIV, , Brasil. Secretaria de Vigilância Em Saúde. Ministério da Saúde. Brasília: Ministério da SaúdeWiener, L.S., Zobel, M., Battles, H., Ryder, C., Transition from a pediatric HIV intramural clinical research program to adolescent and adult community-based care services: Assessing transition readiness (2007) Soc Work Health Care, 46, pp. 1-19Vijayan, T., Benin, A.L., Wagner, K., Romano, S., Andiman, W.A., We never thought this would happen: Transitioning care of adolescents with perinatally acquired HIV infection from pediatrics to internal medicine (2009) AIDS Care, 21, pp. 1222-1229Hosek, S.G., Harper, G.W., Robinson, W.L., Identity development in adolescents living with HIV (2002) Journal of Adolescence, 25 (4), pp. 355-364. , DOI 10.1006/jado.2002.0480Gilliam, P.P., Ellen, J.M., Leonard, L., Kinsman, S., Jevitt, C.M., Straub, D.M., Transition of Adolescents with HIV to Adult Care: Characteristics and Current Practices of the Adolescent Trials Network for HIV/AIDS Interventions (2010) J Assoc Nurses AIDS Care, , Jun 9. Epub ahead of printSchidlow, D.V., Fiel, S.B., Life beyond pediatrics. Transition of chronically ill adolescents from pediatric to adult health care systems (1990) Med Clin North Am, 74, pp. 1113-1120Viner, R.M., Transition of care from paediatric to adult services: One part of improved health services for adolescents (2008) Archives of Disease in Childhood, 93 (2), pp. 160-163. , DOI 10.1136/adc.2006.103721Resnick, M.D., Bearman, P.S., Blum, R., Bauman, K.E., Harris, K.M., Jones, J., Protecting adolescents from harm. Findings from the National Longitudinal Study on Adolescent Health (1997) JAMA, 278, pp. 823-832(2009) AIDS Epidemic Update: November 2009, , http://www.unaids.org/en/KnowledgeCentre/HIVData/EpiUpdate/EpiUpdArchive/ 2009/default.asp, Geneva: UNAIDSAccess: 11/08/201

    Imbalance of naive and memory T lymphocytes with sustained high cellular activation during the first year of life from uninfected children born to HIV-1-infected mothers on HAART

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    The immune consequences of in utero HIV exposure to uninfected children whose mothers were submitted to highly active antiretroviral therapy (HAART) during gestation are not well defined. We evaluated 45 HIV-exposed uninfected (ENI) neonates and 45 healthy unexposed control (CT) neonates. All HIV-infected mothers received HAART during pregnancy, and the viral load at delivery was <50 copies/mL for 56.8%. Twenty-three ENI neonates were further evaluated after 12 months and compared to 23 unexposed healthy age-matched infants. Immunophenotyping was performed by flow cytometry in cord and peripheral blood. Cord blood lymphocyte numbers did not differ between groups. However, ENI neonates had a lower percentage of naive T cells than CT neonates (CD4+, 76.6 vs 83.1%, P < 0.001; CD8+, 70.9 vs 79.6%, P = 0.003) and higher percentages of central memory T cells than CT neonates (CD4+, 13.9 vs 8.7%, P < 0.001; CD8+, 8.6 vs 4.8%, P = 0.001). CD38 mean fluorescence intensity of T cells was higher in ENI neonates (CD4+, 62.2 vs 52.1, P = 0.007; CD8+, 47.7 vs 35.3, P < 0.001). At 12 months, ENI infants still had higher mean fluorescence intensity of CD38 on T cells (CD4+, 34.2 vs 23.3, P < 0.001; CD8+, 26.8 vs 19.4, P = 0.035). Despite effective maternal virologic control at delivery, HIV-exposed uninfected children were born with lower levels of naive T cells. Immune activation was present at birth and remained until at least 12 months of age, suggesting that in utero exposure to HIV causes subtle immune abnormalities.FAPESPCoordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES

    Efeito de reguladores de crescimento no potencial osmótico de tomateiro (Lycopersicon esculentum Mill. cv. Angela)

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    This research deals with the effects of exogenous growth regulators on leaf osmotic potential of tomato cultivar "Angela". To study the influence of growth substances on osmotic potentia, (2-chloroethyl) trimethylammonium chloride (CCC) at concentration of 2,000 ppm, succinic acid-2,2-dirnethylhydrazide (Alar) (3,000 ppm), and potassium gibberellate (Gibrel) (100 ppm) were applied. The leaf osmotic potential established everyday during six days showed that plants treated with Gibrel presented lower (negative) osmotic potential. CCC promoted better equilibrium in the osmotic potential of tomato plants. Leaves of tomato cultivar "Angela" presented higher osmotic potential in the morning in relation to leaves collected in the afternoon.A importância do estudo do potencial osmótico das plantas deve-se ao fato deste parâmetro ser considerado o principal componente do potencial hídrico, refletindo o equilíbrio de água na planta. Determinou-se o potencial osmótico foliar do tomateiro (Lycopersicon esculentum Mill. cv. "Angela") através de osmômetro de precisão. As plantas haviam sido tratadas com cloreto de (2-cloroetil) trimetilamônio (CCC) 2000 ppm, ácido succínico-2,2-dimetilhidrazida (Alar) 3000 ppm e giberelato de potássio (Gibrel) 100 ppm, além do controle. Verificou-se que o Gibrel promoveu uma redução no potencial osmótico; sendo que Alar provocou flutuações no potencial do tomateiro "Angela". O CCC causou maior equilíbrio no potencial osmótico foliar do tomateiro. Observou-se que as folhas da cultivar "Angela'' mostraram potencial osmótico mais alto pela manhã com relação ao período da tarde

    Imaging Spectroscopy of a White-Light Solar Flare

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    We report observations of a white-light solar flare (SOL2010-06-12T00:57, M2.0) observed by the Helioseismic Magnetic Imager (HMI) on the Solar Dynamics Observatory (SDO) and the Reuven Ramaty High-Energy Solar Spectroscopic Imager (RHESSI). The HMI data give us the first space-based high-resolution imaging spectroscopy of a white-light flare, including continuum, Doppler, and magnetic signatures for the photospheric FeI line at 6173.34{\AA} and its neighboring continuum. In the impulsive phase of the flare, a bright white-light kernel appears in each of the two magnetic footpoints. When the flare occurred, the spectral coverage of the HMI filtergrams (six equidistant samples spanning \pm172m{\AA} around nominal line center) encompassed the line core and the blue continuum sufficiently far from the core to eliminate significant Doppler crosstalk in the latter, which is otherwise a possibility for the extreme conditions in a white-light flare. RHESSI obtained complete hard X-ray and \Upsilon-ray spectra (this was the first \Upsilon-ray flare of Cycle 24). The FeI line appears to be shifted to the blue during the flare but does not go into emission; the contrast is nearly constant across the line profile. We did not detect a seismic wave from this event. The HMI data suggest stepwise changes of the line-of-sight magnetic field in the white-light footpoints.Comment: 14 pages, 7 figures, Accepted by Solar Physic

    Efeitos de estimulantes vegetais na germinação do arroz (Oryza sativa L: cv. IAC - 165)

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    The objective of the present work was to study the effect of Triacontanol and Agrostemmin on rice seeds by evalluating germination, coleoptile and seedling root growing, under laboratory conditions. The Petri dishes received 10 ml of solution (ether and benzene) for Triacontanol treatments and distilled water for the Agrostemmin treatments. Results showed that the treatments does not present significant effects in relation to germination percent but a statistically significant effect with respect to seedling root growing was observed.O presente trabalho teve como objetivo estudar o efeito de Triacontanol e Agrostemin em sementes de arroz, através da avaliação da germinação, do crescimento de coleóptiles e raízes das plântulas, em condições de laboratório. As placas de Petri receberam 10 ml de solução (éter e benzeno) correspondente aos tratamentos com Triacontanol, enquanto as dosagens de Agrostemin foram aplicadas em solução de água destilada. Verificou-se que nenhum dos tratamentos mostraram efeitos significativos sobre a porcentagem de germinação, mas provocaram um crescimento diferencial estatisticamente significativo em relação as radículas

    Extreme Ultra-Violet Spectroscopy of the Lower Solar Atmosphere During Solar Flares

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    The extreme ultraviolet portion of the solar spectrum contains a wealth of diagnostic tools for probing the lower solar atmosphere in response to an injection of energy, particularly during the impulsive phase of solar flares. These include temperature and density sensitive line ratios, Doppler shifted emission lines and nonthermal broadening, abundance measurements, differential emission measure profiles, and continuum temperatures and energetics, among others. In this paper I shall review some of the advances made in recent years using these techniques, focusing primarily on studies that have utilized data from Hinode/EIS and SDO/EVE, while also providing some historical background and a summary of future spectroscopic instrumentation.Comment: 34 pages, 8 figures. Submitted to Solar Physics as part of the Topical Issue on Solar and Stellar Flare
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