303 research outputs found

    The Social Acceptability of Personal Carbon Trading in China

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    Whether personal carbon trading (PCT) can be successfully implemented, as a public policy, critically depends on its social acceptability. For China, the biggest carbon emission country, public attitude towards personal carbon trading has a significant impact on its energy strategy or even the world’s. The purpose of this research is to investigate the social acceptability of personal carbon trading in China with the method of focus group and questionnaire. In order to understand Chinese citizens’ evaluations on personal carbon trading and how these attitudes are generated, researchers interviewed 32 individuals in four groups in-depth. Before and after the interview, questionnaires of almost the same content were sent to investigate whether more information on personal carbon trading will change interviewees’ attitudes towards it. A comparison was then made between public attitudes towards personal carbon trading and those towards carbon tax. Two significant conclusions are drawn from this study. First, personal carbon trading has gained more popularity compared with carbon tax. Second, the introduction of personal carbon trading to China still faces great challenges from the social atmosphere. Keywords: Personal carbon trading; PCT; Carbon tax; social acceptability

    Takayasu's arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>The simultaneous presence of Takayasu's arteritis and beta thalassemia trait is a rare combination. To the best of our knowledge, this is the first case report on Takayasu's arteritis and beta thalassemia presenting together.</p> <p>Case presentation</p> <p>This is a case report of a 23-year-old Asian woman of Pakistani descent who presented with a headache, blurred vision and dizziness.</p> <p>Conclusion</p> <p>The correct diagnosis of our patient was based on clinical suspicion, appropriate imaging studies, and deliberation of the differential diagnosis. The management of our patient depended on the correct diagnosis of both the diseases.</p

    Implementation of centralised, numerical busbar protection using distributed photonic current sensors

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    Fast and robust busbar protection is critical to ensuring the reliability and safety of transmission substations and the connected power networks. For the most part, modern numerical busbar protection techniques remain based upon the interrogation of conventional current transformers (CTs) by copper secondary wiring feeding multiple IEDs ("peripheral units") which communicate measured currents to one or more central units using dedicated optical fibre digital communication links. Numerical busbar protection requires copper secondary wiring in the yard that presents safety and cost challenges, particularly during substation refits. With the transition to digital substations, it becomes possible to collect all the measurements in sample value format from different bays on a common network (the process bus) without having dedicated wiring for each measurement, however there is a limited number of sample value streams that busbar protection IEDs available today can handle. Combining multiple active units into a single system and substantially eliminating copper wiring would lead to reductions in civil work, materials, outage times, and therefore to both capital and operational expenditure. In this paper, we report on the design and testing of the first centralised busbar protection scheme that makes use of distributed photonic current sensors. By utilising distributed, passive sensors which are interrogated purely using standard optical fibre, the requirement for active units in the substation yard is completely eliminated. Additionally, the use of copper wiring from CTs to measurement units may be eliminated. The scheme, designed and built for Statnett by Synaptec, will be installed and trialled at Statnett's Furuset R&D substation near Oslo, Norway. A prototype centralised busbar protection algorithm, validated with the University of Strathclyde, will run on the central merger unit to prove the principle of centralised busbar protection using a single active IED. The goal of developing and deploying the presented system is to enhance both redundancy and failure detection probability of busbar protection, and to enable the safe, continued operation of the busbar protection scheme during refurbishment projects for control systems. With further development, or following integration of the instrumentation platform with a conventional protection IED, it is proposed that this technique could be deployed in a business as usual context

    Strategies for Inhibiting Advanced Glycation Endproduct (Age) Induced Vascular Calcification in a Smooth Muscle Cell Culture Model

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    Vascular calcification is implicated in a range of cardiovascular disease mechanisms, leading to an associated increase in morbidity and mortality. One such trigger are advanced glycation endproducts (AGEs), the tissue accumulation of which increases with age and is more prevalent in diabetic subjects due to oxidative stress and poor glycaemic control. The aim of this study was to investigate the osteogenic potential of AGEs and elucidate mechanisms of inhibiting these processes in a smooth muscle cell (SMC) culture model. Osteogenic differentiation of SMCs was induced using β-glycerophosphate (β-GP), carboxymethyllysine (CML), carboxyethyllysine (CEL) methylglyoxal (MGO) and glycated low density lipoprotein (gly-LDL). The cells were subsequently treated with aminoguanidine (AG), an inhibitor of AGE formation, and novel glycomimetic compounds in order to determine their anti-calcification potential in vitro using qPCR, ELISA, Alkaline phosphatase (ALP) activity and Alizarin red staining. Gly-LDL (10 µg/ml) and CML (2.5nM) increased the level of calcification observed compared to the β-GP (5 mM) positive control after 21 days (p < 0.05), with gly-LDL induced calcification apparent after 14 days. Both AG (250 µM) and the novel glycomimetic compounds reduced the level of mineralisation observed at 21 days compared with osteogenic treatments (p < 0.05). CEL (2.5 nM) and MGO (0.1 mM) both induced calcification, however mineralization was not as extensive as with β-GP. When compared to the structure of CML, the side-chain of CEL contains an extra methyl group, suggesting this group impacts RAGE receptor binding. It was also shown that β-GP combined with increased glucose concentration induced more extensive calcification unlike low glucose levels and β-GP alone. ALP activity, when stimulated with β-GP, CML and gly-LDL was greater at day 4 than at day 7, with AG reducing ALP activity measurements at day 4. Gly-LDL increases gene expression of OCN at day 4 compared with β-GP and CML, however this was reduced at day 7, corresponding with an increased expression of OPN and OPG. NOTCH-3 gene expression was also reduced at day 7. Gene expression of OPN, OPG and NOTCH-3 were reduced at both day 4 and day 7 compared with osteogenic treatments (β-GP, CML and gly-LDL). In summary, we conclude that gly-LDL and CML are potent inducers of calcification compared with β-GP, and that their osteogenic potential can be modulated by both AG and novel glycomimetic compounds

    Progressive Preference Articulation for Decision Making in Multi-Objective Optimisation Problems

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    This paper proposes a novel algorithm for addressing multi-objective optimisation problems, by employing a progressive preference articu- lation approach to decision making. This enables the interactive incorporation of problem knowledge and decision maker preferences during the optimisation process. A novel progressive preference articulation mechanism, derived from a statistical technique, is herein proposed and implemented within a multi-objective framework based on evolution strategy search and hypervolume indicator selection. The proposed algo- rithm is named the Weighted Z-score Covariance Matrix Adaptation Pareto Archived Evolution Strategy with Hypervolume-sorted Adaptive Grid Algorithm (WZ-HAGA). WZ-HAGA is based on a framework that makes use of evolution strategy logic with covariance matrix adaptation to perturb the solutions, and a hypervolume indicator driven algorithm to select successful solutions for the subsequent generation. In order to guide the search towards interesting regions, a preference articulation procedure composed of four phases and based on the weighted z-score approach is employed. The latter procedure cascades into the hypervolume driven algorithm to perform the selection of the solutions at each generation. Numerical results against five modern algorithms representing the state-of-the-art in multi-objective optimisation demonstrate that the pro- posed WZ-HAGA outperforms its competitors in terms of both the hypervolume indicator and pertinence to the regions of interest

    Investigation Outcomes of Tuberculosis Suspects in the Health Centers of Addis Ababa, Ethiopia

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    BACKGROUND: Little is known about the prevalence of tuberculosis (TB) and HIV among TB suspects in primary health care units in Ethiopia. METHODS: In the period of February to March, 2009, a cross sectional survey was done in 27 health centers of Addis Ababa to assess the prevalence of TB and HIV among TB suspects who have > = 2 weeks symptoms of TB such as cough, fever and weight loss. Diagnosis of TB and HIV was based on the national guidelines. Information concerning socio-demographic variables and knowledge of the respondents about TB was collected using pretested questionnaire. RESULTS: Of the 545 TB suspects, 506 (92.7%) of them participated in the study. The prevalence of both pulmonary and extra pulmonary TB was 46.0% (233/506). The smear positivity rate among pulmonary TB suspect was 21.3%. Of the TB suspects, 298 (58.9%) of them were tested for HIV and 27.2% (81/298) were HIV seropositive. Fifty percent of the HIV positive TB suspects had TB. TB suspects who had a contact history with a TB patient in the family were 9 times more likely to have TB than those who did not have a contact history, [OR = 9.1, (95%CI:4.0, 20.5)]. Individuals who had poor [OR = 5.2, (95%CI: 2.3, 11.2)] and fair knowledge [OR = 3.7, (95%CI: 1.3, 10.4)] about TB were more likely to have TB than individuals who had good knowledge. CONCLUSION: In conclusion, the prevalence of TB among TB suspects with duration of 2 or more weeks is high. Fifty percent of the HIV positive TB suspects had TB. Case finding among TB suspects with duration of 2 or more weeks should be intensified particularly among those who have a contact history with a TB patient
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