382 research outputs found

    Predictors of Success in Advance Higher Education: A Case in Northwest Samar State University, Philippines

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    Teachers play a significant role in the preparation of our youth as they make important decisions about education, work, and life.  Existing studies on the correlations between teaching proficiency and academic performance of the students are primarily limited to elementary, secondary, and tertiary levels. Considering the big difference between advance higher education and other educational levels, there is a need to explore the relationship of the teaching proficiency to the academic performance of the students in advance higher education. This study made use of the descriptive-correlation research design. Survey questionnaires were distributed to all advance higher education faculty members and students from School Years 2015 to 2017 at Northwest Samar State University. Statistical tools like frequency and percentage distribution, means, standard deviations, and regression analysis were used for the analysis of the data. Results showed that most of the advance higher education faculty members are male, married, doctorate holders, professionals, research-oriented, very satisfactory performers, and possess good financial status. The best predictor of the academic performance of the advance higher education students is the work experience of the faculty members

    PDB17 BURDEN OF ILLNESS ASSOCIATED WITH SYMPTOMS OF DIABETIC PERIPHERAL NEUROPATHY AND DIABETIC RETINOPATHY

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    Computing prime factors with a Josephson phase qubit quantum processor

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    A quantum processor (QuP) can be used to exploit quantum mechanics to find the prime factors of composite numbers[1]. Compiled versions of Shor's algorithm have been demonstrated on ensemble quantum systems[2] and photonic systems[3-5], however this has yet to be shown using solid state quantum bits (qubits). Two advantages of superconducting qubit architectures are the use of conventional microfabrication techniques, which allow straightforward scaling to large numbers of qubits, and a toolkit of circuit elements that can be used to engineer a variety of qubit types and interactions[6, 7]. Using a number of recent qubit control and hardware advances [7-13], here we demonstrate a nine-quantum-element solid-state QuP and show three experiments to highlight its capabilities. We begin by characterizing the device with spectroscopy. Next, we produces coherent interactions between five qubits and verify bi- and tripartite entanglement via quantum state tomography (QST) [8, 12, 14, 15]. In the final experiment, we run a three-qubit compiled version of Shor's algorithm to factor the number 15, and successfully find the prime factors 48% of the time. Improvements in the superconducting qubit coherence times and more complex circuits should provide the resources necessary to factor larger composite numbers and run more intricate quantum algorithms.Comment: 5 pages, 3 figure

    Generation of Three-Qubit Entangled States using Superconducting Phase Qubits

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    Entanglement is one of the key resources required for quantum computation, so experimentally creating and measuring entangled states is of crucial importance in the various physical implementations of a quantum computer. In superconducting qubits, two-qubit entangled states have been demonstrated and used to show violations of Bell's Inequality and to implement simple quantum algorithms. Unlike the two-qubit case, however, where all maximally-entangled two-qubit states are equivalent up to local changes of basis, three qubits can be entangled in two fundamentally different ways, typified by the states ∣GHZ>=(∣000>+∣111>)/2|\mathrm{GHZ}> = (|000> + |111>)/\sqrt{2} and ∣W>=(∣001>+∣010>+∣100>)/3|\mathrm{W}> = (|001> + |010> + |100>)/\sqrt{3}. Here we demonstrate the operation of three coupled superconducting phase qubits and use them to create and measure ∣GHZ>|\mathrm{GHZ}> and ∣W>|\mathrm{W}> states. The states are fully characterized using quantum state tomography and are shown to satisfy entanglement witnesses, confirming that they are indeed examples of three-qubit entanglement and are not separable into mixtures of two-qubit entanglement.Comment: 9 pages, 5 figures. Version 2: added supplementary information and fixed image distortion in Figure 2

    Integrating evidence, politics and society: a methodology for the science–policy interface

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    There is currently intense debate over expertise, evidence and ‘post-truth’ politics, and how this is influencing policy formulation and implementation. In this article, we put forward a methodology for evidence-based policy making intended as a way of helping navigate this web of complexity. Starting from the premise of why it is so crucial that policies to meet major global challenges use scientific evidence, we discuss the socio-political difficulties and complexities that hinder this process. We discuss the necessity of embracing a broader view of what constitutes evidence—science and the evaluation of scientific evidence cannot be divorced from the political, cultural and social debate that inevitably and justifiably surrounds these major issues. As a pre-requisite for effective policy making, we propose a methodology that fully integrates scientific investigation with political debate and social discourse. We describe a rigorous process of mapping, analysis, visualisation and sharing of evidence, constructed from integrating science and social science data. This would then be followed by transparent evidence evaluation, combining independent assessment to test the validity and completeness of the evidence with deliberation to discover how the evidence is perceived, misunderstood or ignored. We outline the opportunities and the problems derived from the use of digital communications, including social media, in this methodology, and emphasise the power of creative and innovative evidence visualisation and sharing in shaping policy

    Clinical factors associated with high glycemic variability defined by coefficient of variation in patients with type 2 diabetes

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    Antecedentes: La Variabilidad Glucémica Alta (VHG) ha convertirse en un predictor más fuerte de hipoglucemia. Sin embargo, aún se desconocen los factores clínicos asociados con el VHG. Objetivo:Determinar las variables clínicas que se asociaron con un coeficiente de variación (CV) superior al 36% evaluado mediante monitorización continua de glucosa (MCG) en un grupo de pacientes con diabetes mellitus. Métodos: Se evaluó una cohorte de pacientes con diabetes tipo 2 (T2D). Se evaluaron variables demográficas, HbA1c, tasa de filtración glomerular (TFG) y régimen de tratamiento. Se realizó un análisis bivariado, para evaluar la asociación entre la variable resultado (CV > 36%) y cada una de las variables independientes. Se construyó un modelo multivariado para evaluar las asociaciones después de controlar las variables de confusión. Resultados:Se analizaron los datos de MCG de 274 pacientes. CV> 36% estuvo presente en 56 pacientes (20,4%). En el análisis bivariado se incluyeron variables demográficas y clínicas, como tiempo desde el diagnóstico, antecedente de hipoglucemia, A1c, FG y tratamiento instaurado. En el análisis multivariante, FG 9% (OR 2,81; IC 1,05,7,51; p:0,04) y antecedentes de hipoglucemia (OR 2,09; IC 1,02, 4,32; p: 0,04) se asociaron con VHG. El tratamiento con iDPP4 (OR 0,39; IC 0,19, 0,82; p: 0,01) y AGLP1 (OR 0,08; IC 0,01, 0,68; p: 0,02) se asoció inversamente con la VG. Conclusión:Variables clínicas como FG 9% y antecedentes de hipoglucemia se asocian a un VG alto. Nuestros datos sugieren que el uso de tecnología y tratamientos capaces de reducir la variabilidad glucémica podría ser útil en esta población para reducir el riesgo de hipoglucemia y mejorar el control glucémico.Q3Background: High glycemic Variability (HGV) has become a stronger predictor of hypoglycemia. However, clinical factors associate with HGV still are unknown. Objective: To determine clinical variables that were associated with a coefficient of variation (CV) above 36% evaluated by continuous glucose monitoring (CGM) in a group of patients with diabetes mellitus. Methods: A cohort of patients with type 2 diabetes (T2D) was evaluated. Demographic variables, HbA1c, glomerular filtration rate (GFR) and treatment regimen were assessed. A bivariate analysis was performed, to evaluate the association between the outcome variable (CV> 36%) and each of the independent variables. A multivariate model was constructed to evaluate associations after controlling for confounding variables. Results: CGM data from 274 patients were analyzed. CV> 36% was present in 56 patients (20.4%). In the bivariate analysis, demographic and clinical variables were included, such as time since diagnosis, hypoglycemia history, A1c, GFR and treatment established. In the multivariate analysis, GFR 9% (OR 2.81; CI 1.05,7.51; p:0.04) and hypoglycemia history (OR 2.09; CI 1.02,4.32; p:0.04) were associated with HGV. Treatment with iDPP4 (OR 0.39; CI 0.19,0.82; p:0.01) and AGLP1 (OR 0.08; CI 0.01,0.68; p:0.02) was inversely associated with GV. Conclusion: Clinical variables such as GFR 9% and a history of hypoglycemia are associated with a high GV. Our data suggest that the use of technology and treatments able to reduce glycemic variability could be useful in this population to reduce the risk of hypoglycemia and to improve glycemic control.Revista Internacional - Indexad

    The impact of COVID-19 on global health journals: An analysis of impact factor and publication trends

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    Background COVID-19 has affected research productivity across all areas of knowledge. Current evidence suggests that COVID-19 has had a blockbuster effect on journal impact factors (JIFs) and publication trends, while little is known on global health journals. Methods Twenty global health journals were included to analyse the impact of COVID-19 on their JIFs and publication trends. Indicator data, including numbers of publications, citations, articles with different types, etc, were extracted from journal websites and Web of Science Core Collection database. The JIFs from 2019 to 2021 were simulated for longitudinal and cross-sectional analyses. Interrupted time-series analysis and non-parametric tests were applied to assess whether COVID-19 had decreased non-COVID-19 publications from January 2018 to June 2022. Results In 2020, 615 out of 3223 publications were COVID-19 related, accounting for 19.08%. The simulated JIFs of 17 out of 20 journals in 2021 were higher than those in 2019 and 2020. Notably, 18 out of 20 journals had a decrease in their simulated JIFs after excluding COVID-19-related publications. Moreover, 10 out of 20 journals decreased their monthly numbers of non-COVID-19 publications after the COVID-19 outbreak. For all the 20 journals as a whole, after the COVID-19 outbreak in February 2020, the total number of non-COVID-19 publications significantly decreased by 14.2 compared with the previous month (p=0.013), and since then, on average, the publications had decreased by 0.6 per month until June 2022 (p<0.001). Conclusions COVID-19 has impacted the structure of COVID-19-related publications, the JIFs of global health journals and their numbers of non-COVID-19 publications. Although journals may benefit from increased JIFs, global health journals should avoid relying on a single metric. More follow-up studies including more years of data with a combination of metrics should be conducted to generate more robust evidence

    Riding the waves of the COVID-19 pandemic in South Korea

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    During the first months of the coronavirus disease 2019 (COVID-19) pandemic in early 2020, South Korea stood as one of the most successful in preventing a nationwide outbreak. The country was unique in that it did so without enforcing massive border restrictions and tight social distancing measures, instead focusing on maximal testing, contact tracing, and treatment. But as the year 2020 went on, the country has suffered second and third waves, each one being larger and harder to combat than the last. The Korean government, however, has been unwilling to impose stringent measures due to potential economic consequences and has still relied on its initial strategies in an attempt to prevent further disease transmission. It is therefore crucial to revisit their position beyond their early successes to re-evaluate the effectiveness of their strategy, and to finally decide if it is time to move on to more drastic measures

    Postharvest management of Heliconia psittacorum x H. spathocircinata cv. Tropics

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    Objetive:&nbsp; Evaluate different techniques to prolong the postharvest life of &nbsp;Heliconia psittacorum x H. spathocircinata cv. Tropics. Design/methodology/approach: Two experiments were carried out; in the first it was evaluated the effect of five pulse solutions [(T1 = control (water); T2 = Hydraflor® 100 (0.5 g L-1); T3 = Hydraflor® 100 (0.5 g L-1) + sucrose (5% w/v); T4 = salicylic acid (1mM) and T5 = salicylic acid (1mM) + sucrose (5% w / v)] prior to storage at 11 ° C and 85 % RH for 10 d. In the second experiment, a wax coating was applied to the heliconia bracts and then maintain at 13 °C and 84% RH for 10 d; after storage the stems were placed in water or salicylic acid solution (1 mM). The results were analyzed by a completely randomized design, 10 replicates were used per treatment, one stem was one experimental unit. An ANOVA and a means comparison test (Tukey, ?=0.05) were performed with the SAS version 9.4. Results: The anatomy of heliconia stems determines their vase life, since they have wide xylem vessels susceptible to cavitation, for which the absorption of water is limited, also and non-functional stomata in the bracts, which increase the loss of moisture from the tissue. The use of pulse solutions or preservatives has little effect in prolonging the life of heliconia stems. Therefore, the application of wax creates a physical barrier that maintains the turgor of the stems, reduces oxidation, maintaining the bracts quality and increased the total postharvest life for 6 d more than the control stems. Study limitations/implications: No limitations were found in this study Findings/conclusions: The postharvest life of heliconia is conditioned by the loss of turgor and low water absorption, which leads to an early wilting of the inflorescences. The application of pulse solutions or preservatives have little effect in prolonging the life of the vase, so the most suitable technique to preserve the quality of the stems is waxing

    PCR reveals significantly higher rates of Trypanosoma cruzi infection than microscopy in the Chagas vector, Triatoma infestans: High rates found in Chuquisaca, Bolivia

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    <p>Abstract</p> <p>Background</p> <p>The Andean valleys of Bolivia are the only reported location of sylvatic <it>Triatoma infestans</it>, the main vector of Chagas disease in this country, and the high human prevalence of <it>Trypanosoma cruzi </it>infection in this region is hypothesized to result from the ability of vectors to persist in domestic, peri-domestic, and sylvatic environments. Determination of the rate of <it>Trypanosoma </it>infection in its triatomine vectors is an important element in programs directed at reducing human infections. Traditionally, <it>T. cruzi </it>has been detected in insect vectors by direct microscopic examination of extruded feces, or dissection and analysis of the entire bug. Although this technique has proven to be useful, several drawbacks related to its sensitivity especially in the case of small instars and applicability to large numbers of insects and dead specimens have motivated researchers to look for a molecular assay based on the polymerase chain reaction (PCR) as an alternative for parasitic detection of <it>T. cruzi </it>infection in vectors. In the work presented here, we have compared a PCR assay and direct microscopic observation for diagnosis of <it>T. cruzi </it>infection in <it>T. infestans </it>collected in the field from five localities and four habitats in Chuquisaca, Bolivia. The efficacy of the methods was compared across nymphal stages, localities and habitats.</p> <p>Methods</p> <p>We examined 152 nymph and adult <it>T. infestans </it>collected from rural areas in the department of Chuquisaca, Bolivia. For microscopic observation, a few drops of rectal content obtained by abdominal extrusion were diluted with saline solution and compressed between a slide and a cover slip. The presence of motile parasites in 50 microscopic fields was registered using 400× magnification. For the molecular analysis, dissection of the posterior part of the abdomen of each insect followed by DNA extraction and PCR amplification was performed using the TCZ1 (5' – CGA GCT CTT GCC CAC ACG GGT GCT – 3') and TCZ2 (5' – CCT CCA AGC AGC GGA TAG TTC AGG – 3') primers. Amplicons were chromatographed on a 2% agarose gel with a 100 bp size standard, stained with ethidium bromide and viewed with UV fluorescence.</p> <p>For both the microscopy and PCR assays, we calculated sensitivity (number of positives by a method divided by the number of positives by either method) and discrepancy (one method was negative and the other was positive) at the locality, life stage and habitat level. The degree of agreement between PCR and microscopy was determined by calculating Kappa (<it>k</it>) values with 95% confidence intervals.</p> <p>Results</p> <p>We observed a high prevalence of <it>T. cruzi </it>infection in <it>T. infestans </it>(81.16% by PCR and 56.52% by microscopy) and discovered that PCR is significantly more sensitive than microscopic observation. The overall degree of agreement between the two methods was moderate (Kappa = 0.43 ± 0.07). The level of infection is significantly different among communities; however, prevalence was similar among habitats and life stages.</p> <p>Conclusion</p> <p>PCR was significantly more sensitive than microscopy in all habitats, developmental stages and localities in Chuquisaca, Bolivia. Overall we observed a high prevalence of <it>T. cruzi </it>infection in <it>T. infestans </it>in this area of Bolivia; however, microscopy underestimated infection at all levels examined.</p
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