22,484 research outputs found

    Comparison of equalisation strategies for multi-carrier CDMA

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    Experience with posttransplant lymphoproliferative disorders in solid organ transplant recipients

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    Nearly 6000 solid organ transplants have been performed at the University of Pittsburgh since 1981. Posttransplant lymphoproliferative disorders (PTLD) have occurred in 131 patients, at a frequency of 2.2%. The majority of cases manifest within 6 months following allograft, but individual lesions may arise several years thereafter. From 1981 to 1989, cyclosporine-A (CsA) served as the primary immunosuppressant in this population. In March of 1989, FK506 was introduced for clinical trials. Since that time, 1421 patients have received FK506 either for primary immunosuppression or as rescue therapy. The frequency of PTLD in this subpopulation is 1.5%. PTLD arising under FK506-containing regimens have clinicopathologic features similar to those arising with CsA immunosuppression. The frequency of PTLD at this point in time is approximately 1%, in kidney allograft patients, 2.7% in liver, 3.3% in heart and 3.8%, in heart/lung or lung recipients. An understanding of the range of histologic appearance is important for the diagnosis of PTLD, especially when it involves the allograft itself. Immunoglobulin heavy chain gene analysis shows that lesions with no rearrangements or with a rearrangement in only a small proportion of cells are more likely to respond to reduced immunosuppression than are those with clonal rearrangement involving a high proportion of cells. However, this distinction is not absolute, and a trial of reduced immunosuppression appears to be indicated regardless of clonal status

    Local majority dynamics on preferential attachment graphs

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    Suppose in a graph GG vertices can be either red or blue. Let kk be odd. At each time step, each vertex vv in GG polls kk random neighbours and takes the majority colour. If it doesn't have kk neighbours, it simply polls all of them, or all less one if the degree of vv is even. We study this protocol on the preferential attachment model of Albert and Barab\'asi, which gives rise to a degree distribution that has roughly power-law P(x)∌1x3P(x) \sim \frac{1}{x^{3}}, as well as generalisations which give exponents larger than 33. The setting is as follows: Initially each vertex of GG is red independently with probability α<12\alpha < \frac{1}{2}, and is otherwise blue. We show that if α\alpha is sufficiently biased away from 12\frac{1}{2}, then with high probability, consensus is reached on the initial global majority within O(log⁥dlog⁥dt)O(\log_d \log_d t) steps. Here tt is the number of vertices and d≄5d \geq 5 is the minimum of kk and mm (or m−1m-1 if mm is even), mm being the number of edges each new vertex adds in the preferential attachment generative process. Additionally, our analysis reduces the required bias of α\alpha for graphs of a given degree sequence studied by the first author (which includes, e.g., random regular graphs)

    Editorial to the Proceedings of the Improving Residential Energy Efficiency International Conference, IREE 2017

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    Editorial to proceedings of Improving Residential Energy Efficiency International Conference, IREE 2017, 16-17 February 2017, Wollongong, Australi
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