Post-extubation stridor after prolonged intubation in the pediatric intensive care unit (PICU): a prospective observational cohort study

Purpose: Prolonged endotracheal intubation may lead to laryngeal damage, with stridor being the most relevant clinical symptom. Our objective was to determine the incidence of post-extubation stridor and their clinical consequences in children within a tertiary referral center and to identify contributing factors. Methods: 150 children, aged 0–16 years, intubated for more than 24 h were prospectively enrolled until discharge of the hospital. Potential relevant factors, thought to mediate the risk of laryngeal damage, were recorded and analyzed. Results: The median duration of intubation was 4 days, ranging from 1 to 31 days. Stridor following extubation occurred in 28 patients (18.7%); 3 of them required reintubation due t

Lessons from France: The Cardiovascular Prevention Clinic in the La Pitié-Salpêtrière Hospital in Paris

Cardiovascular disease is the principal cause of morbidity and mortality in the Netherlands. In this background, various initiatives have been launched to reduce the frequency of cardiovascular disease. One of those is the creation of clinical units with a special focus on prevention of cardiovascular disease. Hitherto, the prevention programmes of these clinics have been heterogeneous and therefore difficult to compare with respect to results. Similar developments in creating clinical initiatives concerning prevention of cardiovascular disease are found across Europe. With this in mind, lessons could be learned from each other’s experiences. In our contribution, we would like to present the Cardiovascular Prevention Clinic in the Pitié- Salpêtrière Hospital in Paris, France, as an interesting example of a well-acknowledged cardiovascular prevention clinic that combines both daily clinical care and cardiovascular science. (Neth Heart J 2007;15:22-6.

Lessons from france: the cardiovascular prevention clinic in the la pitie-salpetriere hospital in paris.

Item does not contain fulltextCardiovascular disease is the principal cause of morbidity and mortality in the Netherlands. In this background, various initiatives have been launched to reduce the frequency of cardiovascular disease. One of those is the creation of clinical units with a special focus on prevention of cardiovascular disease. Hitherto, the prevention programmes of these clinics have been heterogeneous and therefore difficult to compare with respect to results. Similar developments in creating clinical initiatives concerning prevention of cardiovascular disease are found across Europe. With this in mind, lessons could be learned from each other's experiences. In our contribution, we would like to present the Cardiovascular Prevention Clinic in the Pitie- Salpetriere Hospital in Paris, France, as an interesting example of a well-acknowledged cardiovascular prevention clinic that combines both daily clinical care and cardiovascular science. (Neth Heart J 2007;15:22-6.)

Center on Disability Studies eNewsletter, March 2024

Welcome to the March 2024 issue of the CDS Quarterly eNewsletter. Join us in celebrating a Developmental Disability Awareness Month (DDAM) and recapping our 39th Annual Pacific Rim International Conference on Disability and Diversity. This issue includes special features that include: DD Council Day at the Capitol; CDS Annual Report (FY 2023); and CDS Project Highlights and Events

Palaeozoic amalgamation of Central Europe: new results from recent geological and geophysical investigations

Multidisciplinary studies of geotransects across the North European Plain and Southern North Sea, and geological reexamination of the Variscides of the North Bohemian Massif, permit a new 3-D reassessment of the relationships between the principal crustal blocks abutting Baltica along the Trans-European Suture Zone (TESZ). Accretion was in three stages: Cambrian accretion of the Bruno-Silesian, Lysogory and Malopolska terranes; end-Ordovician/early Silurian accretion of Avalonia; and early Carboniferous accretion of the Armorican Terrane Assemblage (ATA). Palaeozoic plume-influenced metabasite geochemistry in the Bohemian Massif explains the progressive rifting away of peri-Gondwanan crustal blocks before their accretion to Baltica. Geophysical data, faunal and provenance information from boreholes, and dated small inliers and cores confirm that Avalonian crust extends beyond the Anglo-Brabant Deformation Belt eastwards to northwest Poland. The location and dip of reflectors along the TESZ and beneath the North European Plain suggest that Avalonian crust overrode the Baltica passive margin, marked by a high-velocity lower crustal layer, on shallowly southwest-dipping thrust planes forming the Heligoland-Pomerania Deformation Belt. The "Variscan orocline" of southwest Poland masks two junctions between the Armorican Terrane Assemblage (ATA) and previously accreted crustal blocks. To the easr is a dextrally transpressive contact with the Bruno-Silesian and Malopolska blocks, accreted in the Cambrian , while to the north is a thrust contact with eastemmost Avalonia deeply buried beneath younger sedimentary cover. In the northeast Bohemian and Rhenohercynian Massifs Devonian "early Variscide" deformation dominated by WNW and NW-directed thrusting, records closure of Ordovician-Devonian seaways between "islands" of the ATA and Avalonia