462 research outputs found
A note on the detection of bean yellow mosaic virus infecting white lupine in Canada
Des symptĂŽmes de mosaĂŻque virale ont Ă©tĂ© observĂ©s dans des champs expĂ©rimentaux de lupin (Lupinus albus) dans Test du Canada. Les plants affectĂ©s montraient des symptĂŽmes de mosaĂŻque, de rĂ©duction et de dĂ©formation des feuilles, et de nanisme du plant. Les symptĂŽmes ont pu ĂȘtre reproduits en serre par inoculation mĂ©canique sur le cultivar de lupin Ultra. Les symptĂŽmes observĂ©s sur des espĂšces diagnostiques, l'observation par microscopie Ă©lectronique, la dĂ©tection sĂ©rologique ELISA et l'analyse immunologique Western ont Ă©tĂ© utilisĂ©s pour identifier le virus prĂ©sent. Un potyvirus, identifiĂ© comme le virus de la mosaĂŻque jaune du haricot (BYMV), a Ă©tĂ© dĂ©tectĂ© dans les plants affectĂ©s. Ces rĂ©sultats sont les premiers Ă caractĂ©riser une maladie virale du lupin au Canada. Puisque le virus est transmis par les pucerons et par la graine, la prĂ©sence du virus peut devenir une limitation Ă la production du lupin.Virus-like symptoms were observed in fields of white lupine (Lupinus albus) in Eastern Canada. Affected plants displayed mosaic, leaf stunting and deformation, and bunchy growth habit. The disease was successfully reproduced in greenhouse by mechanical inoculation of white lupine cv. Ultra. The causal virus was identified as bean yellow mosaic virus (BYMV) by symptomatology on diagnostic species, electron microscopy, enzyme linked immunosorbent assay (ELISA) and immunodetection after Western blotting. This is the first report of a viral disease of lupine in Canada. BYMV may represent a significant limitation to lupine culture since it is transmitted by aphids and through infected seed
Influence of heavy modes on perturbations in multiple field inflation
We investigate linear cosmological perturbations in multiple field
inflationary models where some of the directions are light while others are
heavy (with respect to the Hubble parameter). By integrating out the massive
degrees of freedom, we determine the multi-dimensional effective theory for the
light degrees of freedom and give explicitly the propagation matrix that
replaces the effective sound speed of the one-dimensional case. We then examine
in detail the consequences of a sudden turn along the inflationary trajectory,
in particular the possible breakdown of the low energy effective theory in case
the heavy modes are excited. Resorting to a new basis in field space, instead
of the usual adiabatic/entropic basis, we study the evolution of the
perturbations during the turn. In particular, we compute the power spectrum and
compare with the result obtained from the low energy effective theory.Comment: 24 pages, 13 figures; v2 substantial changes in sec.V; v3 matching
the published version on JCA
Can forest management based on natural disturbances maintain ecological resilience?
Given the increasingly global stresses on forests, many ecologists argue that managers must maintain ecological resilience: the capacity of ecosystems to absorb disturbances without undergoing fundamental change. In this review we ask: Can the emerging paradigm of natural-disturbance-based management (NDBM) maintain ecological resilience in managed forests? Applying resilience theory requires careful articulation of the ecosystem state under consideration, the disturbances and stresses that affect the persistence of possible alternative states, and the spatial and temporal scales of management relevance. Implementing NDBM while maintaining resilience means recognizing that (i) biodiversity is important for long-term ecosystem persistence, (ii) natural disturbances play a critical role as a generator of structural and compositional heterogeneity at multiple scales, and (iii) traditional management tends to produce forests more homogeneous than those disturbed naturally and increases the likelihood of unexpected catastrophic change by constraining variation of key environmental processes. NDBM may maintain resilience if silvicultural strategies retain the structures and processes that perpetuate desired states while reducing those that enhance resilience of undesirable states. Such strategies require an understanding of harvesting impacts on slow ecosystem processes, such as seed-bank or nutrient dynamics, which in the long term can lead to ecological surprises by altering the forest's capacity to reorganize after disturbance
Erratum : estimates of foil thickness, signal, noise, and nuclear heating of imaging bolometers for ITER
Section 3.2.1 last sentence, "channels" should be "channel". Section 3.2.2 first sentence "m/r" should be "ÎŒ/Ï". Section 3.3 end of 3rd line "form" should be "from"
Study of the Linked Dipole Chain Model in heavy quark production at the Tevatron
We present calculations of charm and beauty production at Tevatron within the
framework of kT-factorization, using the unintegrated gluon distributions as
obtained from the Linked Dipole Chain model. The analysis covers transverse
momentum and rapidity distributions and the azimuthal correlations between b
and bbar quarks (or rather muons from their decay) which are powerful tests for
the different unintegrated gluon distributions. We compare the theoretical
results with recent experimental data taken by D0 and CDF collaborations at the
Tevatron Run I and II.Comment: 16 page
Estimates of foil thickness, signal, noise, and nuclear heating of imaging bolometers for ITER
Imaging bolometers have been studied for ITER to serve as a complementary diagnostic to the resistive bolometers for the measurement of radiated power. Two tangentially viewing InfraRed imaging Video Bolometers (IRVB) could be proposed for an ITER equatorial port, one having a view of the entire plasma cross-section (core viewing) and one tilted down 43 degrees from the horizontal to view the divertor (divertor viewing). The IRVBs have 7 cm (horizontal) by 9 cm (vertical) Pt sensor foils, 6 mm Ă 6 mm apertures, 15 Ă 20 pixels and focal lengths of 7.8 cm and 21 cm, respectively. Using SANCO and SOLPS models for a 840 m3 plasma radiating 67.3 MW, synthetic images from the IRVBs are calculated to estimate the maximum signal strengths to be 246 W/m2 and 62 W/m2, respectively. We propagate the X-ray energy spectra from the models through the synthetic diagnostics to give the photon energy spectrum for each IRVB pixel, which are used to calculate the fraction of the power absorbed by the foil as a function of foil thickness. Using a criteria of >95% absorbed power fraction, we selected foil thicknesses of 30 ÎŒm and 10 ÎŒm, respectively. We used these thicknesses and assumed IR systems having 105 fps, 1024Ă1280 pixels and sensitivities of 15 mK, to calculate the IRVB sensitivities of 3.19 W/m2 and 1.05 W/m2, and signal to noise ratios of 77 and 59, respectively. Using the Monte Carlo Nuclear Particle code we calculated for the core viewing IRVB the foil heating by neutrons to be 1.0 W/m2 and by gammas to be 117 W/m2. This indicates that countermeasures may be needed to remove the nuclear heating signal
Features of heavy physics in the CMB power spectrum
The computation of the primordial power spectrum in multi-field inflation
models requires us to correctly account for all relevant interactions between
adiabatic and non-adiabatic modes around and after horizon crossing. One
specific complication arises from derivative interactions induced by the
curvilinear trajectory of the inflaton in a multi-dimensional field space. In
this work we compute the power spectrum in general multi-field models and show
that certain inflaton trajectories may lead to observationally significant
imprints of `heavy' physics in the primordial power spectrum if the inflaton
trajectory turns, that is, traverses a bend, sufficiently fast (without
interrupting slow roll), even in cases where the normal modes have masses
approaching the cutoff of our theory. We emphasise that turning is defined with
respect to the geodesics of the sigma model metric, irrespective of whether
this is canonical or non-trivial. The imprints generically take the form of
damped superimposed oscillations on the power spectrum. In the particular case
of two-field models, if one of the fields is sufficiently massive compared to
the scale of inflation, we are able to compute an effective low energy theory
for the adiabatic mode encapsulating certain relevant operators of the full
multi-field dynamics. As expected, a particular characteristic of this
effective theory is a modified speed of sound for the adiabatic mode which is a
functional of the background inflaton trajectory and the turns traversed during
inflation. Hence in addition, we expect non-Gaussian signatures directly
related to the features imprinted in the power spectrum.Comment: 41 pages, 6 figures, references updated, minor modifications. Version
to appear in JCAP. v4: Equations (4.28) and (4.30) and Figures 5 and 6
correcte
Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas
Diet is associated with cancer prognosis, including head and neck cancer (HNC), and has been hypothesized to influence epigenetic state by determining the availability of functional groups involved in the modification of DNA and histone proteins. The goal of this study was to describe the association between pretreatment diet and HNC tumor DNA methylation. Information on usual pretreatment food and nutrient intake was estimated via food frequency questionnaire (FFQ) on 49 HNC cases. Tumor DNA methylation patterns were assessed using the Illumina Goldengate Methylation Cancer Panel. First, a methylation score, the sum of individual hypermethylated tumor suppressor associated CpG sites, was calculated and associated with dietary intake of micronutrients involved in one-carbon metabolism and antioxidant activity, and food groups abundant in these nutrients. Second, gene specific analyses using linear modeling with empirical Bayesian variance estimation were conducted to identify if methylation at individual CpG sites was associated with diet. All models were controlled for age, sex, smoking, alcohol and HPV status. Individuals reporting in the highest quartile of folate, vitamin B12 and vitamin A intake, compared with those in the lowest quartile, showed significantly less tumor suppressor gene methylation, as did patients reporting the highest cruciferous vegetable intake. Gene specific analyses identified differential associations between DNA methylation and vitamin B12 and vitamin A intake when stratifying by HPV status. These preliminary results suggest that intake of folate, vitamin A and vitamin B12 may be associated with the tumor DNA methylation profile in HNC and enhance tumor suppression
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Pretreatment dietary intake is associated with tumor suppressor DNA methylation in head and neck squamous cell carcinomas
Diet is associated with cancer prognosis, including head and neck cancer (HNC), and has been hypothesized to influence epigenetic state by determining the availability of functional groups involved in the modification of DNA and histone proteins. The goal of this study was to describe the association between pretreatment diet and HNC tumor DNA methylation. Information on usual pretreatment food and nutrient intake was estimated via food frequency questionnaire (FFQ) on 49 HNC cases. Tumor DNA methylation patterns were assessed using the Illumina Goldengate Methylation Cancer Panel. First, a methylation score, the sum of individual hypermethylated tumor suppressor associated CpG sites, was calculated and associated with dietary intake of micronutrients involved in one-carbon metabolism and antioxidant activity, and food groups abundant in these nutrients. Second, gene specific analyses using linear modeling with empirical Bayesian variance estimation were conducted to identify if methylation at individual CpG sites was associated with diet. All models were controlled for age, sex, smoking, alcohol and HPV status. Individuals reporting in the highest quartile of folate, vitamin B12 and vitamin A intake, compared with those in the lowest quartile, showed significantly less tumor suppressor gene methylation, as did patients reporting the highest cruciferous vegetable intake. Gene specific analyses identified differential associations between DNA methylation and vitamin B12 and vitamin A intake when stratifying by HPV status. These preliminary results suggest that intake of folate, vitamin A and vitamin B12 may be associated with the tumor DNA methylation profile in HNC and enhance tumor suppression
Formation and Evolution of Supermassive Black Holes
The correlation between the mass of supermassive black holes in galaxy nuclei
and the mass of the galaxy spheroids or bulges (or more precisely their central
velocity dispersion), suggests a common formation scenario for galaxies and
their central black holes. The growth of bulges and black holes can commonly
proceed through external gas accretion or hierarchical mergers, and are both
related to starbursts. Internal dynamical processes control and regulate the
rate of mass accretion. Self-regulation and feedback are the key of the
correlation. It is possible that the growth of one component, either BH or
bulge, takes over, breaking the correlation, as in Narrow Line Seyfert 1
objects. The formation of supermassive black holes can begin early in the
universe, from the collapse of Population III, and then through gas accretion.
The active black holes can then play a significant role in the re-ionization of
the universe. The nuclear activity is now frequently invoked as a feedback to
star formation in galaxies, and even more spectacularly in cooling flows. The
growth of SMBH is certainly there self-regulated. SMBHs perturb their local
environment, and the mergers of binary SMBHs help to heat and destroy central
stellar cusps. The interpretation of the X-ray background yields important
constraints on the history of AGN activity and obscuration, and the census of
AGN at low and at high redshifts reveals the downsizing effect, already
observed for star formation. History appears quite different for bright QSO and
low-luminosity AGN: the first grow rapidly at high z, and their number density
decreases then sharply, while the density of low-luminosity objects peaks more
recently, and then decreases smoothly.Comment: 31 pages, 13 figures, review paper for Astrophysics Update
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