55 research outputs found
Low Reynolds number hydrodynamics of asymmetric, oscillating dumbbell pairs
Active dumbbell suspensions constitute one of the simplest model system for
collective swimming at low Reynolds number. Generalizing recent work, we derive
and analyze stroke-averaged equations of motion that capture the effective
hydrodynamic far-field interaction between two oscillating, asymmetric
dumbbells in three space dimensions. Time-averaged equations of motion, as
those presented in this paper, not only yield a considerable speed-up in
numerical simulations, they may also serve as a starting point when deriving
continuum equations for the macroscopic dynamics of multi-swimmer suspensions.
The specific model discussed here appears to be particularly useful in this
context, since it allows one to investigate how the collective macroscopic
behavior is affected by changes in the microscopic symmetry of individual
swimmers.Comment: 10 pages, to appear in EPJ Special Topic
Out-of-equilibrium evolution of quantum fields in the hybrid model with quantum back reaction
The hybrid model with a scalar "inflaton" field coupled to a "Higgs" field
with a broken symmetry potential is one of the promising models for inflation
and (p)reheating after inflation. We consider the nonequilibrium evolution of
the quantum fields of this model with quantum back reaction in the Hartree
approximation, in particular the transition of the Higgs field from the
metastable "false vacuum" to the broken symmetry phase. We have performed the
renormalization of the equations of motion, of the gap equations and of the
energy density, using dimensional regularization. We study the influence of the
back reaction on the evolution of the classical fields and of the quantum
fluctuations. We observe that back reaction plays an important role over a wide
range of parameters. Some implications of our investigation for the preheating
stage after cosmic inflation are presented.Comment: 35 pages, 16 eps figures, revtex4; v2: typos corrected and references
added, accepted for publication in Physical Review
Non-vacuum Solutions of Bianchi Type VI_0 Universe in f(R) Gravity
In this paper, we solve the field equations in metric f(R) gravity for
Bianchi type VI_0 spacetime and discuss evolution of the expanding universe. We
find two types of non-vacuum solutions by taking isotropic and anisotropic
fluids as the source of matter and dark energy. The physical behavior of these
solutions is analyzed and compared in the future evolution with the help of
some physical and geometrical parameters. It is concluded that in the presence
of isotropic fluid, the model has singularity at and represents
continuously expanding shearing universe currently entering into phantom phase.
In anisotropic fluid, the model has no initial singularity and exhibits the
uniform accelerating expansion. However, the spacetime does not achieve
isotropy as in both of these solutions.Comment: 20 pages, 5 figures, accepted for publication in Astrophys. Space Sc
Dark energy as a mirage
Motivated by the observed cosmic matter distribution, we present the
following conjecture: due to the formation of voids and opaque structures, the
average matter density on the path of the light from the well-observed objects
changes from Omega_M ~ 1 in the homogeneous early universe to Omega_M ~ 0 in
the clumpy late universe, so that the average expansion rate increases along
our line of sight from EdS expansion Ht ~ 2/3 at high redshifts to free
expansion Ht ~ 1 at low redshifts. To calculate the modified observable
distance-redshift relations, we introduce a generalized Dyer-Roeder method that
allows for two crucial physical properties of the universe: inhomogeneities in
the expansion rate and the growth of the nonlinear structures. By treating the
transition redshift to the void-dominated era as a free parameter, we find a
phenomenological fit to the observations from the CMB anisotropy, the position
of the baryon oscillation peak, the magnitude-redshift relations of type Ia
supernovae, the local Hubble flow and the nucleosynthesis, resulting in a
concordant model of the universe with 90% dark matter, 10% baryons, no dark
energy, 15 Gyr as the age of the universe and a natural value for the
transition redshift z_0=0.35. Unlike a large local void, the model respects the
cosmological principle, further offering an explanation for the late onset of
the perceived acceleration as a consequence of the forming nonlinear
structures. Additional tests, such as quantitative predictions for angular
deviations due to an anisotropic void distribution and a theoretical derivation
of the model, can vindicate or falsify the interpretation that light
propagation in voids is responsible for the perceived acceleration.Comment: 33 pages, 2 figs; v2: minor clarifications, results unchanged; v3:
matches the version published in General Relativity and Gravitatio
Dark Energy from structure: a status report
The effective evolution of an inhomogeneous universe model in any theory of
gravitation may be described in terms of spatially averaged variables. In
Einstein's theory, restricting attention to scalar variables, this evolution
can be modeled by solutions of a set of Friedmann equations for an effective
volume scale factor, with matter and backreaction source terms. The latter can
be represented by an effective scalar field (`morphon field') modeling Dark
Energy.
The present work provides an overview over the Dark Energy debate in
connection with the impact of inhomogeneities, and formulates strategies for a
comprehensive quantitative evaluation of backreaction effects both in
theoretical and observational cosmology. We recall the basic steps of a
description of backreaction effects in relativistic cosmology that lead to
refurnishing the standard cosmological equations, but also lay down a number of
challenges and unresolved issues in connection with their observational
interpretation.
The present status of this subject is intermediate: we have a good
qualitative understanding of backreaction effects pointing to a global
instability of the standard model of cosmology; exact solutions and
perturbative results modeling this instability lie in the right sector to
explain Dark Energy from inhomogeneities. It is fair to say that, even if
backreaction effects turn out to be less important than anticipated by some
researchers, the concordance high-precision cosmology, the architecture of
current N-body simulations, as well as standard perturbative approaches may all
fall short in correctly describing the Late Universe.Comment: Invited Review for a special Gen. Rel. Grav. issue on Dark Energy, 59
pages, 2 figures; matches published versio
Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)
BACKGROUND:
Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.
METHODS:
Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights.
FINDINGS:
5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease.
INTERPRETATION:
International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems
AlteraçÔes nas reservas de sementes de Dalbergia nigra ((Vell.) Fr. All. ex Benth.) durante a hidratação
Seed imbibitions is the first stage of the germination process and is characterized by the hydration of tissues and cells and the activation and/or induction of the enzymes responsible for mobilizing reserves for respiration and the construction of new cell structures. The objective of this study was to investigate the alterations in reserve substances during slow hydration of Bahia Rosewood (Dalbergia nigra) seeds in water. Seeds from two different lots (Lot I and II) were placed in saturated desiccators (95-99% RH) to hydrate at 15 and 25 °C until water contents of 10, 15, 20 and 25% were reached. At each level of hydration, changes in lipid reserves, soluble carbohydrates, starch and soluble proteins were evaluated. The mobilization of reserves was similarly assessed in both lots, with no differences being observed between the two hydration temperatures. Lipid contents showed little variation during hydration, while the contents of soluble carbohydrates and starch decreased after the 15% water content level. Soluble proteins showed a gradual tendency to decrease between the control (dry seeds) up to 25% water content
Mouse Chromosome 3
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46995/1/335_2004_Article_BF00648421.pd
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